Oral lichen planus patients. Medical search. Frequent questions

Oral lichen planus (OLP) is a common, chronic inflammatory dermatologic condition that often involves the skin, oral mucosa and/or genital mucosa. (jcda.ca)
Oral lichen planus (OLP) is a chronic mucocutaneous disorder that presents in a wide range of clinical forms, such as unilateral or bilateral white striations, papules, or plaques on the buccal mucosa, labial mucosa, tongue, and gingiva. (medscape.com)
Plaquelike oral lichen planus on the buccal mucosa on the left side. (medscape.com)
Lichen planus is a chronic systemic disease that commonly involves the mucosa of the oral cavity, most often in the absence of skin lesions. (bvsalud.org)
Oral lichen planus and lichenoid reactions are autoimmune type inflammatory conditions of the oral mucosa with similar clinical and histological characteristics. (ecancer.org)
Lichen planus is a chronic disease that can affect the skin (including scalp), nails and any lining mucosa and it could be oral, esophageal, vaginal, or skin. (dentalproductsreport.com)
The etiology of lichen planus is not completely understood but researchers think that genetics and immunity may be involved and that the body is reacting to an antigen of sorts (like an allergic reaction) within the skin or mucosa. (dentalproductsreport.com)
Compared with healthy mucosa, the oral mucosa affected by oral lichen planus may be more sensitive to C albicans and to the exogenous mutagens found in tobacco, alcohol, and betel quid. (medscape.com)
In 1982, Pelisse and colleagues reintroduced a similar variant of mucosal LP as the vulvovaginal-gingival syndrome with erosive lesions involving the oral and vulvovaginal mucosa [ 10 ]. (hindawi.com)
Lichen planus is a chronic inflammatory disease of unknown origin, which most commonly affects individuals between 30-60 years of age and is characterized by different types of lesions involving the skin and mucosa . (amboss.com)
Lichen planus can affect the skin , mucosa , scalp, genitalia, and nails , and manifests with varying symptoms depending on the subtype of the disease. (amboss.com)
Oral hairy leukoplakia (OHL) is an EBV-associated condition of the oral mucosa, which is often painless. (nih.gov)
Physicians must be aware of the rare but nevertheless possible adverse events associated with topical steroid use, particularly when such medication is prescribed over a long period for inflammatory diseases of the oral mucosa. (nih.gov)
Oral lichen planus (OLP) is a chronic inflammatory disease that causes bilateral white striations, papules, or plaques on the buccal mucosa, tongue, and gingivae. (medscape.com)
Younes F, Quartey EL, Kiguwa S, Partridge M. Expression of TNF and the 55-kDa TNF receptor in epidermis, oral mucosa, lichen planus and squamous cell carcinoma. (medscape.com)
Clinically, these two entities can be quickly differentiated, as recurrent oral aphthae typically occur on the non-keratinized non-attached mucosa, whereas recurrent intra-oral herpes occurs on the attached mucosa, such as the hard palate and gums. (dermatologytimes.com)
Keywords: Oral mucosa, Oral health, Quality of life. (who.int)
to a more patient-centered oral individuals, and the oral mucosa among other health delivery systems that focus on a person's functions, serves as a protective barrier against social, emotional and physical experience. (who.int)

Three OLP patients (3%) developed squamous cell carcinoma or dysplasia. (jcda.ca)
2 Of those who develop OLP, a subset of patients (0-37%, mean 4.59%) may develop oral squamous cell carcinoma. (jcda.ca)
Recent data suggest that OLR present a greater percentage of malignant transformation than OLP and, although the association between cancer and OLP has been documented in scientific reports, there is no association between squamous cell carcinoma and cutaneous lichen planus [ 4 - 6 ]. (ecancer.org)
The most important complication of oral lichen planus (OLP) is the development of oral squamous cell carcinoma (OSCC) but this is a very controversial matter. (ncl.ac.uk)
Biopsy also helps detect squamous cell carcinoma , the risk of which is increased in lichen planus. (amboss.com)
Agha-Hosseini, F, Mirzaii‐Dizgah, I, Farmanbar, N & Abdollahi, M 2012, Oxidative stress status and DNA damage in saliva of human subjects with oral lichen planus and oral squamous cell carcinoma. (ac.ir)

Oral lichen planus treatment offers favorable clinical results over time due to its widespread prevalence. (magiran.com)
The visit was documented in their dental charts, and patients with a clinical diagnosis of OLP were included in the study. (jcda.ca)
Although classic cutaneous LP (CCLP) and oral LP (OLP) are basically known as the different subtypes of the same disease sharing the common histopathological features, they actually have significant differences both in the clinical behavior and in the molecular inflammatory pathogenesis. (deu.edu.tr)
Moreover, oral lichenoid reactions (OLR) is a term used to describe clinical and histopathological lesions similar to OLP but with an identifiable etiologic factor. (ecancer.org)
Patients with OLP had a significantly increased risk of OSCC, irrespective of the clinical type of OLP and therapy. (ncl.ac.uk)
These tests may be of limited clinical value because oral C albicans is present in at least 70% of all healthy persons. (medscape.com)
Oral LP (OLP) can be the sole clinical presentation of the disease or accompanied by cutaneous or other mucosal manifestations including the genital area, gastrointestinal tract, and eyes. (hindawi.com)
It is found predominantly in HIV-positive patients and is considered a clinical indicator of immunosuppression. (nih.gov)
Abe, A, Ito Y, Hayashi H, Momokita M, Taniguchi S & Nakayama, A 2022, Evaluation of the classification and clinical characteristics of oral lichen planus and its treatment effect in different clinical types: a retrospective study. (ac.ir)
Although curcumin has shown significant efficacy in cell culture studies, it has shown limited efficacy in clinical studies when administered in conventional oral formulations. (researchgate.net)
Typically, the clinical diagnosis of lichen planus is made when it presents as the class variant, characterized by purple, polygonal papules. (jcadonline.com)
Wagner G, Rose C, Sachse MM. Clinical variants of lichen planus. (jcadonline.com)
Weston G, Payette M. Update on lichen planus and clinical variants. (jcadonline.com)
Introduction: oral lichen planus (OLP) is a common oral mucosal disease with various clinical manifestations. (bvsalud.org)
By using immunohistochemistry, the expressions of cluster of differentiation 4 (CD4) and cluster of differentiation 8 (CD8) will be evaluated in biopsy samples taken from OLP patients who exhibit various clinical presentations. (bvsalud.org)
Pharmacokinetics of tazarotene cream 0.1% after a single dose and after repeat topical applications at clinical or exaggerated application rates in patients with acne vulgaris or photodamaged skin. (druglib.com)
Oral lichen planus: a preliminary clinical study on treatment with tazarotene. (druglib.com)
A clinical evaluation of tazarotene 0.1% gel, with and without a high- or mid-high-potency corticosteroid, in patients with stable plaque psoriasis. (druglib.com)

The lesions of cutaneous lichen planus typically resolve within 1-2 years, whereas the lesions of oral lichen planus are long lasting and persist for 20 years or longer. (medscape.com)

Reported associations between oral lichen planus and systemic diseases may be coincidental, because (1) oral lichen planus is relatively common, (2) oral lichen planus occurs predominantly in older adults, and (3) many drugs used in the treatment of systemic diseases trigger the development of oral lichenoid lesions as an adverse effect. (medscape.com)
OBJECTIVE: We sought to determine whether viral transcripts were present within the skin of patients with HCV and LP, and if systemic virologic response to interferon alfa and ribavirin correlated with response of the LP.Materials and methods A total of 4 men and 1 woman all presented with cutaneous eruptions of LP, and 1 had oral LP lesions. (thedoctorsdoctor.com)
We herein report three illustrative cases of heart failure due to cardiac sarcoidosis in patients who were or were not diagnosed with preceding systemic sarcoidosis. (go.jp)
Furthermore, underlying systemic diseases need to be ruled out, such as HIV, inflammatory bowel disease or celiac disease, as severe recurrent oral aphthae can be the initial presentation of these diseases. (dermatologytimes.com)
Several autoimmune blistering diseases present with oral ulcerations, and, according to Dr. Morrison, these lesions are generally associated with more serious diseases, such as pemphigus, pemphigoid, systemic diseases and malignancies. (dermatologytimes.com)
6 Treatment is identical to other cutaneous forms of LP. In localized cases, topical corticosteroids are considered first-line therapy, followed by narrowband ultraviolet B. There are numerous options for generalized or refractory cases, including systemic or intramuscular corticosteroids, plaquenil, dapsone, oral retinoids, or apremilast. (jcadonline.com)

The main sites are inner forearm, wrist, legs, ankles, and face.Lichen Planus affecting mucous membranes is termed Mucosal Lichen Planus. (homoeoonline.com)
In Mucosal Lichen Planus, the main presentation is white patches or white, lacy net-like pattern, ulcers or patches of irregular redness.Like for other skin disorders, Homeopathy is very effective as a remedy for Lichen Planus patients too. (homoeoonline.com)

Cutaneous lichen planus (CLP) most commonly involves the flexor surfaces of the extremities and presents as small itchy violaceous Papules in middle-aged adults. (hindawi.com)
Cutaneous Lichen Planus patients with papules and extreme skin dryness respond very well to Sulphur. (homoeoonline.com)
Lichen planus is a recurrent, pruritic, inflammatory eruption characterized by small, discrete, polygonal, flat-topped, violaceous papules that may coalesce into rough scaly plaques, often accompanied by oral and/or genital lesions. (msdmanuals.com)
This image shows small papules with a sheen in cross-lighting typical of lichen planus. (msdmanuals.com)
This image shows papules and plaques resulting from lichen planus. (msdmanuals.com)
This photo shows papules and plaques of lichen planus. (msdmanuals.com)
This image shows violaceous flat-topped papules coalescing into plaques on the dorsal hand of a patient with lichen planus. (msdmanuals.com)

Lichen planus (LP) is a chronic inflammatory and immune mediated disease that affects the skin, nails, hair, and mucous membranes. (hindawi.com)
Lichen Planus is a chronic non-infectious inflammatory condition affecting the skin and mucous membranes inside the mouth.Lichen Planus is an autoimmune disorder. (homoeoonline.com)
This means that the immune system targets cells of the oral mucous membranes. (homoeoonline.com)
Erosive oral lichen planus (OLP) is an auto-immune disease affecting skin and mucous membranes which results in an. (pasteur.fr)

Oral lichen planus predominantly occurs in adults older than 40 years, although younger adults and children can be affected. (medscape.com)

This retrospective study was carried out from 1387 to 1398 on 40 OLP samples (24non-erosive-atrophic and 16 erosive-atrophic forms) in the Oral Pathology Department of Mashhad Dental School. (magiran.com)
Of possible significance, elevated concentrations of interleukin-6 (IL-6) and neopterin in saliva and serum of patients with the erosive-atrophic form of oral lichen planus suggest they may be involved in the etiology of this disease variation. (medscape.com)
Symptomatic oral lichen planus (ie, atrophic or erosive disease) characteristically waxes and wanes, although the associated white patches do not resolve. (medscape.com)
Patients with atrophic (erythematous) or erosive (ulcerative) disease commonly have significant local morbidity. (medscape.com)
Oral lichen planus can present as white streaks and plaques in the mouth or as an atrophic red epithelium in addition to ulcerations (erosive lichen planus). (dermatologytimes.com)
Punch biopsy showed an effaced and markedly thinned epidermis with overlying compact hyperkeratosis, a band-like lymphocytic infiltrate filling the papillary dermis, and numerous colloid bodies and melanophages along the dermal-epidermal junction, all consistent with atrophic lichen planus (LP). The patent was started on topical corticosteroids and showed an improvement in his symptoms at his four-month follow-up appointment. (jcadonline.com)

The burden of the disease is higher in some variants including hypertrophic LP and erosive oral LP, which may have a more chronic pattern. (hindawi.com)

According to a small 2015 study , raspberry leaf extract improved symptoms in people with oral lichen planus, an inflammatory condition that causes sores in the mouth. (greatist.com)

A small percentage of patients may develop malignant transformation and, thus, require long-term monitoring. (jcda.ca)
Recent data suggest that oral lichenoid reactions (OLR) present a greater percentage of malignant transformation than oral lichen planus (OLP). (ecancer.org)
OLP is considered an oral potentially malignant disorder (OPMD) but its malignant transformation is controversial because of the restrictive criteria for diagnosis. (dentalproductsreport.com)

[ 19 ] Research published in 2015 also suggests that osteopontin, CD44, and survivin may be involved in the pathogenesis of oral lichen planus. (medscape.com)
The role of autoimmunity in the pathogenesis is supported by many autoimmune features of oral lichen planus, including its chronicity, onset in adults, predilection for females, association with other autoimmune diseases, occasional tissue-type associations, depressed immune-suppressor activity in patients with oral lichen planus, and the presence of autocytotoxic T-cell clones in lichen planus lesions. (medscape.com)
Although relatively frequent, oral lichen planus is the target of much controversy, mainly in relation to its pathogenesis and possible potential for malignancy. (bvsalud.org)
Oral lichen planus (OLP) is a relatively common mucocutaneous disorder, and its causative factors and pathogenesis are not fully understood. (biomedcentral.com)
The pathogenesis of oral lichen planus. (medscape.com)

The specific antigen that triggers lichen planus is unknown, although it may be a self-peptide (or altered self-peptide), in which case lichen planus would be a true autoimmune disease. (medscape.com)
Current data suggest that oral lichen planus (OLP) is a T-cell-mediated autoimmune disease in which autocytotoxic CD8 + T cells trigger the apoptosis of oral epithelial cells. (medscape.com)
Some researchers view it as an autoimmune disorder, but more research is needed to classify it this way.Severity and subsequent disability caused by lichen planus varies from inconsequential to severe. (dentalproductsreport.com)
In evaluating the current evidence on the prevalence of autoimmune disorders in patients with oral lichen planus (OLP) and their magnitude of association, a comorbidity between autoimmune thyroid diseases and OLP and between diabetes mellitus and OLP was found. (dentalproductsreport.com)
The diagnosis of dysplasia in the OLP poses an additional difficulty due to the fact that the affected oral epithelium per se develops changes related to autoimmune aggression. (ugr.es)
Lichen planus (LP) is thought to be caused by a T cell-mediated autoimmune reaction against basal epithelial keratinocytes in people with genetic predisposition. (msdmanuals.com)

Reticulated, lacy, bluish white, linear lesions (Wickham striae) are a hallmark of oral lichen planus, especially on the buccal mucosae. (msdmanuals.com)

however, 70% to 80% of patients with HCV go on to develop chronic liver disease during a prolonged period of up to 40 years, and up to 50% of them may remain relatively asymptomatic during that time. (thedoctorsdoctor.com)
An 81-year-old HIV-negative woman, treated for 3 months with topical steroids for oral lichen planus, developed an asymptomatic white, corrugated, non-removable plaque with vertical folds on the lateral edge of the tongue. (nih.gov)

Although the occurrence of oral lichen planus is common, an accurate diagnosis is necessary so that the correct treatment can be established. (bvsalud.org)
Objectives Previous studies have shown that patients with lichen planus (LP) have an increased occurrence of inflammation-related dyslipidemia. (deu.edu.tr)
Most recently, many reports appeared of the occurrence of lichen planus after administration of different types of hepatitis B vaccines. (thedoctorsdoctor.com)
San Francisco - Patients presenting with oral ulcers is not an uncommon occurrence, but the precise etiology of these lesions may at times be a source of confusion to the clinician. (dermatologytimes.com)

Ulcerative oral lichen planus on the dorsum of the tongue. (medscape.com)
An REU (reticular/hyperkeratotic, erosive/erythematous, ulcerative) scoring system was adopted and compared between the OLP patients with and without hematinic deficiencies. (biomedcentral.com)
In addition, advise patients to regularly examine their mouths and seek the help of a specialist if persistent red or ulcerative oral mucosal lesions develop. (medscape.com)

Patients in the study who took ignatia saw a reduction in lesions and reported fewer pain symptoms. (healthline.com)
Re-examine patients with oral lichen planus (OLP) during active treatment, and monitor lesions for reduction in mucosal erythema and ulceration and alleviation of symptoms. (medscape.com)
Advise patients with oral lichen planus to pay attention to when symptoms are exacerbated or when lesions change. (medscape.com)
Current immunosuppressive therapies usually control oral mucosal erythema, ulceration, and symptoms in patients with oral lichen planus with minimal adverse effects. (medscape.com)
When these two symptoms are present in addition to the ulcers, then medicine Merc Sol provides a very beneficial treatment.Along with these symptoms, a few patients also feela metallic taste in mouth. (homoeoonline.com)
This may be due to a lack of awareness of the causes, signs, and symptoms of oral cancer, combined with infrequent screenings. (drmarclazare.com)
Oral cancer symptoms can vary widely depending on which area of the mouth is affected. (drmarclazare.com)
Scheduling an appointment with Dr. Lazare to discuss your oral cancer symptoms is of paramount importance due to the critical nature of early detection. (drmarclazare.com)
Symptoms of oral cancer can vary widely based on individual circumstances, making professional evaluation essential. (drmarclazare.com)

In addition to the assessment of the oral cavity, Dr. Lazare has adopted the use of ViziLite Plus® into his Manhattan dental practice for oral cancer testing. (drmarclazare.com)

All patients were diagnosed consecutively from July 2015 to March 2019 at the Department of Oral Medicine, Shanxi Provincial People's Hospital, China. (biomedcentral.com)
Review of the 2019 report reveals that diabetes mellitus remains the most common cause of ESRD, responsible for approximately 42% of all patients on renal replacement therapy. (medscape.com)

The list of offending agents causing a lichenoid reaction is extensive and includes medications, oral hygiene products, and occasionally, metallic filling materials. (dentalproductsreport.com)

Four hundred and two patients with histologically confirmed OLP diagnosed from January 1988 to July 1999, were followed-up to the end of February 2001. (ncl.ac.uk)
Manifests with diffuse lesions that closely resemble lichen planus but are not histologically identical. (amboss.com)
Oral lichen planus was established histologically in forty paraffin-embedded tissue samples. (bvsalud.org)

We conducted retrospective chart reviews of adult patients with OLP who presented to oral medicine and oral pathology clinics in 2 provinces between September 2016 and January 2020. (jcda.ca)
We reviewed the dental charts of patients who presented to oral medicine and oral pathology at the Montreal General Hospital (MGH) in Montréal, Quebec, and to a private oral and maxillofacial pathology clinic, the Atlantic Oral Surgery & Dental Implant Centre in St. John's, Newfoundland. (jcda.ca)
All adult patients (≥18 years of age) who presented to the MGH clinic or the Atlantic Oral Surgery & Dental Implant Centre between 1 Sept. 2016 and 31 Jan. 2020 for an oral pathology appointment were screened for eligibility. (jcda.ca)
The patients were seen by a specialist in oral medicine and oral pathology for diagnosis and management. (jcda.ca)
OLP diagnosis was based on the American Academy of Oral and Maxillofacial Pathology position paper. (jcda.ca)
2 Two oral pathology specialists were involved in the diagnosis of patients. (jcda.ca)
Oral and maxillofacial pathology. (bmj.com)
This practice, widespread among oral pathology professionals, has resulted in the underestimation of the potential for malignancy of OLP. (ugr.es)
[ 22 ] Oral lichen planus is a common noninfectious oral mucosal disorder among adult patients who attend oral pathology and oral medicine clinics. (medscape.com)
Journal of Oral Pathology & Medicine , 41: 736-740. (ac.ir)

Therefore, early in the formation of oral lichen planus lesions, CD8 + T cells may recognize an antigen associated with the major histocompatibility complex (MHC) class I on keratinocytes. (medscape.com)
The expression or unmasking of the lichen planus antigen may be induced by drugs (lichenoid drug reaction), contact allergens in dental restorative materials or toothpastes (contact hypersensitivity reaction), mechanical trauma (Koebner phenomenon), viral infection, or other unidentified agents. (medscape.com)

Lichen planus and diabetes mellitus: systematic review and meta-analysis. (jcadonline.com)
Lichen planus and hepatitis C virus: a multicenter study of patients with oral lesions and a systematic review. (jcadonline.com)

Physical and histopathological examinations were carried out to confirm the diagnosis of oral lichen planus. (bvsalud.org)
Based upon histological findings and in situ hybridisation showing numerous EBV-infected epithelial cells, a diagnosis of oral hairy leucoplakia was made. (nih.gov)
An oral cancer dentist or doctor may be able to make the diagnosis, depending on which area of the mouth is affected. (drmarclazare.com)

Cutaneous examination of patients with ESRD has shown that 50-100% of patients have at least 1 dermatologic condition. (medscape.com)

Our patient was recently diagnosed with diabetes mellitus (DM), which has a long standing, controversial association with LP, as described in a recent meta-analysis that cited contradictory results. (jcadonline.com)

If the GvHD is severe and requires intense immunosuppression involving steroids and additional agents to get under control, the patient may develop severe infections [12] as a result of the immunosuppression and may die of infection. (wikipedia.org)
Treatment primarily consists of high-dose topical steroids but may also include oral steroids and phototherapy in cases of extensive or steroid -refractory disease. (amboss.com)

The prevalence of oral lichen planus in the United States is unknown. (medscape.com)
Prevalence of Oral Mucosal Lesions and Oral Health Related Quality of Life among Adolescents in a Rural Nigerian Population. (who.int)

Lichen planus in children: a possible complication of hepatitis B vaccines. (thedoctorsdoctor.com)
Lichen planus (LP) has been reported as a complication of hepatitis B vaccination in both adults and children. (thedoctorsdoctor.com)
Lichen planus associated with hepatitis C virus: No viral transcripts are found in the lichen planus, and effective therapy for hepatitis C virus does not clear lichen planus. (thedoctorsdoctor.com)
5 Routine screening for hepatitis C has been recommended for patients with recurrent LP, although this association is likely only significant in certain geographic areas. (jcadonline.com)

However, it is believed that a T-cell-mediated response, which triggers the apoptosis of oral epithelial cells, may contribute to the development of this disorder. (bvsalud.org)

oral lesions may occur without cutaneous lesions. (msdmanuals.com)

They are usually symmetrically distributed, most commonly on the flexor surfaces of the wrists, legs, trunk, glans penis, and oral and vaginal mucosae but can be widespread. (msdmanuals.com)

1. Know the risks of oral diseases for people with diabetes. (cdc.gov)
Antioxidants provide a novel way of addressing oral diseases and conditions such as lichen planus, xerostomia, gingivitis, periodontitis, and aphthous ulcers. (dentaleconomics.com)
Health-Related Quality caries and other oral diseases. (who.int)
INTRODUCTION focus on diseases only (such as caries, periodontitis, Oral health is important to the quality of life of al gingivitis et cetera. (who.int)
Quality Of Life (OHRQOL) to serve as adjuncts for Researchers have defined an oral mucosal lesion measuring outcomes associated with (OML) as any abnormal alteration in colour, surface diseases/conditions. (who.int)

Oral Lichen Planus includes inner cheeks, lips, tongue and gums. (homoeoonline.com)
Patients who really benefit from Borax have ulcers inside the cheeks and on tongue. (homoeoonline.com)
Oral HPV or human papillomavirus can cause the development of cancerous lesions on the tongue, tonsils, or back of the throat (oropharynx). (drmarclazare.com)

A total of 236 OLP patients (41 males and 195 females, mean age, 51.70 ± 13.99 years) and 226 gender- and age-matched healthy controls (52 males and 174 females, mean age, 49.46 ± 17.26 years) were enrolled in this retrospective study (Table 1 ). (biomedcentral.com)
In retrospective studies, less than 5% of patients with oral lichen planus who were not using tobacco products developed oral SCC. (medscape.com)

Patients with grade IV GvHD usually have a poor prognosis. (wikipedia.org)
However, a 2016 study found that the prognosis for patients with grade IV GvHD has improved in recent years. (wikipedia.org)
Among patients, those with higher percentages of CD4+CD25high T cells had a poor prognosis than did those with lower percentages. (nel.edu)

Up to 25% of individuals with severe oral dysplasia will progress to developing invasive oral cancer. (ucl.ac.uk)
This proof of concept study will test a novel non-invasive device as diagnostic tool for oral cancer and pre-cancer (dysplasia). (ucl.ac.uk)
Dysplasia in oral lichen planus: relevance, controversies and challenges. (ugr.es)
The presence of epithelial dysplasia has emerged as the most powerful indicator for assessing cancer risk in oral potentially malignant disorders in routine practice. (ugr.es)

Lichen planus only affects about 2% of the population and women over the age of 50 are most often affected. (dentalproductsreport.com)
Lichen planus (LP) is a chronic inflammatory disorder that most often affects middle-aged adults. (hindawi.com)
Oral lichen planus affects approximately 1-2% of the general adult population, although the prevalence of the disease is unknown in many areas. (medscape.com)
Oral lichen planus affects all racial groups. (medscape.com)

In patients with oral lichen planus, the chronic inflammatory response and the simultaneous healing response of epithelial wounds may increase the likelihood of cancer-forming gene mutations. (medscape.com)
Patients with periodontitis have a chronic inflammatory response, which results in chronic oxidative stress. (dentaleconomics.com)

proposed that OLP was one of the leading oral manifestations of iron deficiency anemia (IDA) and could be diagnosed in a third of patients with IDA in their oral mucosal exam [ 16 ]. (biomedcentral.com)
Typical and reverse Takotsubo syndromes as initial manifestations of consecutive Addisonian crises in a 38-year-old patient: the heart has its reasons! (bmj.com)
Dermatologic manifestations of renal disease are not uncommon findings in patients with end-stage renal disease (ESRD). (medscape.com)
A high prevalence of cutaneous disorders is expected, because most patients with ESRD have an underlying disease process with cutaneous manifestations. (medscape.com)

The dense subepithelial mononuclear infiltrate in oral lichen planus is composed of T cells and macrophages, and there are increased numbers of intraepithelial T cells. (medscape.com)

Lichen planus is a pruritic inflammatory dermatosis of unknown origin. (thedoctorsdoctor.com)

The programme is focussed on oral cancer and precancer, facial pain, chronic oral infections and inflammation, salivary gland and jaw bone disorders and dental caries. (ucl.ac.uk)

Hypertension, thyroid disorders and diabetes were present in 32%, 28% and 17% of patients, respectively. (jcda.ca)
Many cutaneous disorders experienced by patients undergoing dialysis have little to do with the uremic syndrome and are related to the same underlying pathologic process that caused the renal disease. (medscape.com)

After fifteen days, both patients presented regression of the lesion. (bvsalud.org)

Among LP subtypes, although the differences were not statistically significant, TG, TC, and LDL-C values were markedly higher in OLP and OLP + CCLP patients compared with CCLP patients. (deu.edu.tr)

In order to examine the role of NFkappabeta in the pathophysiology of CFS, this study examines the production of NFkappabeta p50 in unstimulated, 10 ng/mL TNF-alpha (tumor necrosis factor alpha) and 50 ng/mL PMA (phorbolmyristate acetate) stimulated peripheral blood lymphocy tes of 18 unmedicated patients with CFS and 18 age-sex matched controls. (nel.edu)

If the scalp is affected, patchy scarring alopecia (lichen planopilaris) may occur. (msdmanuals.com)

Thus, the objective of this paper is to report two cases of lichen planus in male patients and to discuss the main aspects of this disease in relation to etiopathogenesis and treatment. (bvsalud.org)
Oral cancer is often diagnosed at an advanced stage, when the disease has spread and curative treatment becomes difficult and complex. (ucl.ac.uk)
Ignatia in the treatment of oral lichen planus. (healthline.com)
Oral lichen planus and its treatment may predispose people to oral C albicans superinfection. (medscape.com)
PURPOSE: Dental anxiety is a common phenomenon influencing the relationship between a patient and a doctor as well as the course of treatment. (who.int)
Incorporating research-based new technologies into our treatment plans enables us to enhance the care we provide for patients in and beyond their oral cavities. (dentaleconomics.com)
It is also of great help in the treatment of lichen Planus. (homoeoonline.com)
Plantago is another natural medicine of great help in the treatment of Oral Lichen Planus. (homoeoonline.com)
A natural medicine that gives wonderful results in the treatment of Lichen Planus is Thuja. (homoeoonline.com)
Thuja proves to be ideal treatment for Lichen Planus of pigmented variety. (homoeoonline.com)
Topical calcineurin inhibitors can also work well, and according to the literature, 88 percent of patients on average respond favorably to topical calcineurin inhibitor treatment. (dermatologytimes.com)
By catching oral cancer early, the treatment process can be more effective and less invasive, leading to better outcomes. (drmarclazare.com)
Randomized comparison of the safety and efficacy of tazarotene 0.1% cream and adapalene 0.3% gel in the treatment of patients with at least moderate facial acne vulgaris. (druglib.com)

Therefore, the present study aimed to investigate the frequency of human papillomavirus (HPV) DNA in oral lichen planus (OLP) tissue samples by the polymerase chain reaction (PCR) method. (magiran.com)
There's 1 other type of lichen planus which is plaque-like and gives the appearance of a dense thickening or the mucosal tissue. (dentalproductsreport.com)
Objective: The present study evaluated the oral tissue expression of micro-RNA (miRNAs) linked to the potential malignant evolution of oral lichen planus (OLP). (researchgate.net)

Conclusions Patients with OLP have a more impaired lipid metabolism and significantly higher atherogenic indexes compared with patients with CCLP. (deu.edu.tr)

This case highlights that 80%-90% recovery is possible in lichen planus with the help of homeopathy. (askdrshah.com)

METHODS: We used mass cytometry with 25 marker panels for T-cell immune profiling in peripheral blood T cells (CD3+) from 22 patients with BEL-treated SLE and 20 controls with non-BEL-treated SLE. (bvsalud.org)

Also, early research suggests that drinking spearmint tea might reduce the severity of male-pattern hair growth based on patient evaluation in women with male-pattern hair growth due to polycystic ovarian syndrome . (medicinenet.com)

Anatomy2

Organisms1

Diseases15

Chemicals and Drugs9

Analytical, Diagnostic and Therapeutic Techniques and Equipment1

Phenomena and Processes1

Mucosa18

Squamous cell carc6

Clinical18

Lesions of oral lichen1

Systemic6

Mucosal Lichen Planus2

Papules7

Mucous membranes4

Predominantly1

Atrophic6

Hypertrophic1

Inflammatory condition that causes1

Malignant transformation3

Pathogenesis5

Autoimmune6

Buccal1

Asymptomatic2

Occurrence4

Ulcerative3

Symptoms9

Cavity1

20192

Lichenoid reaction1

Histologically3

Pathology10

Antigen2

Systematic review2

Diagnosis3

Dermatologic condition1

Diabetes mellitus1

Steroids2

Prevalence of oral2

Hepatitis4

Apoptosis of oral epithelial cells1

Cutaneous lesions1

Glans penis1

Diseases5

Tongue3

Retrospective2

Prognosis3

Dysplasia4

Affects4

Chronic inflammatory response2

Manifestations4

Infiltrate1

Pruritic1

Inflammation1

Disorders2

Lesion1

Subtypes1

Pathophysiology1

Planopilaris1

Treatment13

Tissue3

Lipid metabolism1

Homeopathy1

Immune1

Severity1