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  • coherence
  • To perform this task, specific characteristics of ballistic photons vs. non-ballistic photons are used, such as time of flight through coherence gated imaging, collimation, wavefront propagation, and polarization. (wikipedia.org)
  • Carl Zeiss Medi
  • The global optical imaging market is dominated by Carl Zeiss Meditec AG (Germany), St. Jude Medical, Inc. (U.S.), and Volcano Corporation (U.S.). Together, these players held a collective market share of around 50%-55% in 2013. (marketsandmarkets.com)
  • Abstract
  • Abstract: This study provides a computational scheme to decode intentional arm movement direction using optical imaging of the motor cortex for future implementation on a neuro-prosthetic device that enables physically disabled patients to navigate a wheelchair using brain-derived signals. (unt.edu)
  • Optics
  • The field of optics is involved in much of today's technology, including imaging and photolithography, which is used to make semiconductors and integrated circuits," said Xiang Zhang, UC Berkeley associate professor of mechanical engineering and principal investigator of the study. (eurekalert.org)
  • Traditionally, ray tracing and geometrical optics have provided the basis for imaging. (umn.edu)
  • However, recent optics and photonics research has focused on phenomena at smaller and smaller length scales or multiple scales, so full PDE models and nonlinear imaging techniques have become necessary to adequately capture the useful optical effects. (umn.edu)
  • Topics of particular interest include: inverse scattering problems, optical imaging, hybrid inverse problems, near-field optics, and nano-optics modeling. (umn.edu)
  • intravascular
  • In the field of cardiovascular medicine, intravascular OCT employs light to produce in situ images with resolution that approaches histology, the authors wrote in their introduction. (medpagetoday.com)
  • St. Jude Medical, Inc. and Volcano Corporation have a diversified product portfolio for optical imaging, which includes OCT systems and catheters for intravascular imaging. (marketsandmarkets.com)
  • Intravascular NIRF technology was developed in the MGH Cardiovascular Research Center (CVRC), in collaboration with colleagues at the Technical University of Munich, and uses special imaging agents to detect cells and molecules involved in vascular processes like clotting and inflammation. (bioopticsworld.com)
  • Recognizing the potential advantage of combining both technologies, the Wellman researchers worked with the MGH-CVRC team, led by Farouc Jaffer, MD, Ph.D., of the MGH Heart Center to develop an integrated OFDI-NIRF imaging system incorporated in the same intravascular probe used for OFDI alone. (bioopticsworld.com)
  • tissue
  • Imaging in the near-infrared (NIR) region has advantages of improved tissue penetration and low tissue autofluorescence which enhances target to background ratios . (plos.org)
  • It facilitates both luminescence and fluorescence measurements, which allows them to image disease progression through tissue and in real time. (photonics.com)
  • Endoscopic imaging, or using cameras inserted directly inside the body's organs to investigate symptoms, is an invasive procedure used to examine and diagnose symptoms of deep tissue disease. (eurekalert.org)
  • By using ultrasonic wave patterns, the researchers can effectively "focus" light within the tissue, which allows them to take images never before accessible through noninvasive means. (eurekalert.org)
  • Therefore, current optical imaging methods cannot use light to access deep tissue from the surface. (eurekalert.org)
  • Therefore, the tissue is turned into a lens that helps us capture and relay the images of deeper structures. (eurekalert.org)
  • By placing the device or patch on the skin, the clinician would be able to easily receive optical information from within the tissue to create images of what's inside without endoscopy's many discomforts and side effects. (eurekalert.org)
  • Recent trends in optical imaging technology advancement focus upon improving image resolution, data acquisition speed, tissue penetration, and contrast enhancement features. (pitchengine.com)
  • To improve the ability of clinicians to detect early stage disease and to treat advanced cancers, we developed a multimodal optical imaging system (MMIS) to evaluate tissue structure in vivo at macroscopic and microscopic scales. (aacrjournals.org)
  • The macroscopic imaging component of the MMIS acquires autofluorescence images of tissue with an excitation wavelength of 405 nm, a field of view of 45 mm, and spatial resolution of 0.1 mm. (aacrjournals.org)
  • Regions of tissue that display reduced blue-green autofluorescence are examined further using the high-resolution imaging component of the MMIS, which is a compact fluorescence microscope coupled to a fiber-optic imaging probe with a 720 μm diameter field-of-view and 4.4 μm spatial resolution. (aacrjournals.org)
  • detection
  • They chose the system because of its luminescence and fluorescence detection capabilities, which allow them to image the progression of tuberculosis and the efficacy of treatment in real time. (photonics.com)
  • Such advances have the potential to translate to very valuable insights for practical imaging applications, ranging from breast cancer diagnosis and brain tumor detection to astronomy. (umn.edu)
  • researchers
  • Researchers are using a new imaging system to study tuberculosis in animal models. (photonics.com)
  • The researchers currently are working to improve the sensitivity of the system by optimizing the imaging methods, by using multiple levels of signal amplification and by optimizing reporter expression. (photonics.com)
  • The researchers showed that the properties of the virtual "lens" can be tuned by changing the parameters of the ultrasonic waves, allowing users to "focus" images taken using the method at different depths through the medium. (eurekalert.org)
  • High-intensity lights shine on the heart, then researchers image and intensify specific wavelengths of light that trigger the dyes. (photonics.com)
  • Using a thin film of silver as the lens and ultraviolet (UV) light, the researchers recorded the images of an array of nanowires and the word "NANO" onto an organic polymer at a resolution of about 60 nanometers. (eurekalert.org)
  • With a superlens, optical microscopes could one day reveal the movements of individual proteins traveling along the microtubules that make up a cell's skeleton, the researchers said. (eurekalert.org)
  • The researchers found that Cerenkov radiation can be observed from a range of positron-b- and a-emitting radionuclides using standard optical imaging devices. (healthimaging.com)
  • Spectrum
  • Optical imaging includes a variety of imaging techniques that rely on illumination light in the ultraviolet, visible and infrared regions of the electromagnetic spectrum. (nature.com)
  • To this end, in late 2007, they purchased an IVIS Spectrum imaging system made by Caliper Life Sciences Inc. of Hopkinton, Mass. (photonics.com)
  • Here for the first time is an integrated mathematical view of the physics and numerical modeling of optical projection lithography that efficiently covers the full spectrum of the important concepts. (spie.org)
  • successfully
  • By taking the advantages of low energy window of light (1.2-3.1 eV, 400-1000 nm) resulting from radiation, radionuclides that emit charged particles such as β + and β − can be successfully imaged with an OI instrument. (plos.org)
  • successfully demonstrated that high-energy β + emitters, 18 F and 13 N, could be used for optical imaging . (plos.org)
  • We successfully image biologically relevant organizations that are similar to the collagen organization found as a stabilized state in compact bones. (osapublishing.org)
  • OFDI
  • Developed at the Wellman Center, OFDI utilizes a fiber-optic probe with a constantly rotating laser tip to create detailed molecular images of interior surfaces such as arterial walls. (bioopticsworld.com)
  • interferometric
  • A new concept of acousto-optical imaging is emerging based on an interferometric setup containing a photorefractive crystal as the recombination plate, and a single detector. (spie.org)
  • techniques
  • Due to the exponential reduction (with respect to distance) of ballistic photons in a scattering medium, often image processing techniques are applied to the raw captured ballistic images, to reconstruct high quality ones. (wikipedia.org)
  • Optical imaging (OI) techniques such as bioluminescence and fluorescence imaging have been widely used to track diseases in a non-invasive manner within living subjects. (plos.org)
  • We hypothesized that radionuclide radiation in the low energy window of light (1.2-3.1 eV, 400-1000 nm) could be imaged using OI techniques and be especially valuable for molecular OI. (plos.org)
  • Owing to technological advancements and an increase in the application areas of optical imaging techniques in the pharmaceutical and biotechnological sectors and medical diagnostics & therapeutics, the optical imaging market recorded a healthy growth rate in the last decade. (pitchengine.com)
  • Lens
  • Lens-free imaging removes the pipes altogether by utilizing an entirely new design," he said. (medgadget.com)
  • The end result of this process is an image taken without using a lens. (medgadget.com)
  • Ozcan envisions this lens-free imaging system as one component in a lab-on-a-chip platform. (medgadget.com)
  • A lens-free microscope has both a much larger field of view and depth of field because the imaging is done by the digital sensor array and is not constrained by a lens. (medgadget.com)
  • In this paper, the team shows that this compression and rarefication effect can be used to sculpt a virtual lens in the target medium for optical imaging. (eurekalert.org)
  • contrast
  • In this method, OCT images are first processed with L 1 - L 0 norm minimization based de-noising and smoothing algorithms to increase the signal-to-noise ratio (SNR) and enhance the contrast between adjacent layers. (osapublishing.org)
  • High-resolution imaging is performed at an excitation wavelength of 455 nm following topical application of proflavine, a fluorescent contrast agent which predominantly stains cell nuclei. (aacrjournals.org)
  • A time series of image data sets of an optical contrast substance in the animal is acquired using an optical detector Each image data set is obtained at a selected time and has the same plurality of pixels, with. (google.es)
  • 2. The method of claim 1 , wherein the optical contrast substance is a dye. (google.es)
  • 7. The method of claim 1 , wherein the step of acquiring a time series of image data sets comprises acquiring a time series of image data sets of a plurality of targeted optical contrast substances. (google.es)
  • 9. The method of claim 1 , wherein the step of analyzing the image data sets is achieved using pixel values obtained at a plurality of time points within the time series such that the plurality of time courses are identified based on calculated spatial and temporal patterns of emission from the optical contrast substance. (google.es)
  • 10. The method of claim 1 , wherein the step of determining a plurality of time courses is a calculation based on the temporal pattern of emission of the optical contrast substance at each pixel. (google.es)
  • 11. The method of claim 1 , wherein the optical contrast substance within the animal are used to identify multiple organs within a single image. (google.es)
  • system
  • Using the system, they imaged nonrecombinant tuberculosis in the lungs of mice, facilitating visualization of disease progression and impact of potential therapies in real time. (photonics.com)
  • An optical imaging system small enough to fit onto an opto-electronic chip provides a variety of benefits. (medgadget.com)
  • And, you can count on the reliable data for your in vivo imaging research from the Pearl Trilogy Small Animal Imaging System. (licor.com)
  • The team first confirmed that the system could provide detailed structural images of a stent implanted in a cadaveric human coronary artery and could accurately identify the presence of fibrin on the stent. (bioopticsworld.com)
  • microscope
  • The optical microscope, invented more than 400 years ago, has tended to grow larger and more complex as it has been modified to image ever-smaller objects with better resolution. (medgadget.com)
  • Ozcan, a researcher at the California NanoSystems Institute at UCLA, makes the analogy that a traditional optical microscope is like a huge set of pipes delivering content, in the form of images, to the user. (medgadget.com)
  • Detector
  • By measuring the intensity of the interference pattern with an optical detector that has a finite width and moving the object by use of a rotation stage, one can obtain the angular directionality of the filter. (osapublishing.org)
  • The invention concerns an optical imaging apparatus comprising a light source, sample holding means, an interferometer, reference means, an objective which is adapted to have its sample side focal plane crossing a sample held in said sample holding means, optical or electro-optical means adapted to produce a ring shaped or multi-spot light source in the front focal plane or any conjugated plane of said objective, at least one detector. (epfl.ch)
  • 6. The method of claim 1 , wherein a field of view of the optical detector includes multiple views of the animal. (google.es)
  • novel
  • These results pave the way for further use and development of CLI as a novel optical imaging modality for the rapid, cost effective, high-throughput screening of radiopharmaceuticals," he said. (healthimaging.com)
  • clinical
  • It provides a new molecular imaging strategy and will likely have significant impact on both small animal and clinical imaging. (plos.org)
  • This report service on Optical Imaging devices in clinical medicine is one of its kinds with 75% of its focus on technological understanding and advancement and a 25% of market engineering standards. (pitchengine.com)
  • The combination of optical imaging with nuclear medicine may offer a new path for imaging medical isotopes, the authors noted, and may provide optical imaging with "an array of approved nuclear tracers already in clinical use today, which can be used immediately, as opposed to fluorescent dyes. (healthimaging.com)
  • coherent
  • If efficiently detected, there are many applications for ballistic photons especially in coherent high resolution medical imaging systems. (wikipedia.org)
  • resolution
  • This image is one of the first acquired by Envisat's Medium Resolution Imaging Spectrometer (MERIS) instrument (27 October 2010 around 7:30 UTC), just a few hours after the Earth-observing satellite reached its new orbit. (esa.int)
  • Berkeley -- A group of scientists at the University of California, Berkeley, is giving new relevance to the term "sharper image" by creating a superlens that can overcome a limitation in physics that has historically constrained the resolution of optical images. (eurekalert.org)
  • Shown is a drawing of nano-scale imaging using a silver superlens that achieves a resolution beyond the optical diffraction limit. (eurekalert.org)
  • At top (A) is the higher resolution image of the word NANO created with a silver superlens. (eurekalert.org)
  • Alterations in nuclear size and crowding are quantified by calculating the mean nuclear-to-cytoplasm ratio in high-resolution images. (aacrjournals.org)
  • We show that SHG signals provide highly contrasted images of the three-dimensional texture of cholesteric patterns with submicrometer lateral resolution. (osapublishing.org)
  • APPROACH
  • The revolutionary FieldBrite™ Xi 2 technology approach to imaging in the Pearl Trilogy Imager allows you to detect smaller and deeper targets accurately in a single acquisition. (licor.com)
  • A top-down approach was used to estimate market size of optical imaging. (pitchengine.com)
  • stent
  • OCT images revealed innovative characteristics of atherosclerotic plaque and stent deployment, as reported in the Journal of Endovascular Therapy . (medpagetoday.com)
  • The OCT maneuver was repeated after stent deployment to acquire images before and after stent dilation. (medpagetoday.com)
  • applications
  • Optical imaging is extensively used for several applications including preclinical research, disease diagnosis, and the study of various cellular and molecular processes in vivo such as protein interactions, protein degradation, and protease activity. (pitchengine.com)