• The target audience of the Scout Report for Science & Engineering is faculty, students, staff, and librarians in the life sciences, physical sciences, and engineering. (wisc.edu)
  • In molecular biology, open reading frames (ORFs) are defined as spans of DNA sequence between the start and stop codons. (wikipedia.org)
  • One common use of open reading frames (ORFs) is as one piece of evidence to assist in gene prediction. (wikipedia.org)
  • Some short ORFs (sORFs), also named Small open reading frames, usually (wikipedia.org)
  • These overlooked ORFs are found throughout the genome, in any reading frame of transcripts, mature or non-coding, and can overlap annotated ORFs in a different reading frame. (biomedcentral.com)
  • As Ribo-seq detects mRNA translation events, it revealed signatures outside of annotated open reading frames (ORFs) defined by reference gene annotations [ 2 ]. (biomedcentral.com)
  • Sequence analysis of a 1.2-kb fragment containing the entire coding sequence of A15 revealed three open reading frames (ORFs), only one of which (ORF II) contains sufficient genetic information to encode for A15. (elsevierpure.com)
  • Poleroviruses contain six major open reading frames (ORFs) labelled ORF 0-5. (qld.gov.au)
  • LINE-1 consists of a 5′-untranslated region (UTR), a 3′-UTR and two types of open reading frames (ORFs) translated into protein [ 6 , 9 - 11 ]. (kosinmedj.org)
  • Using genetic variation from 71,702 human genomes, we assess patterns of selection in translated upstream open reading frames (uORFs) in 5'UTRs. (nature.com)
  • In particular, upstream open reading frames (uORFs) are segments of 5′UTR mRNA sequences that can initiate and terminate translation upstream of protein-coding start codons. (nature.com)
  • The research, titled "Circadian ribosome profiling reveals a role for the Period2 upstream open reading frame in sleep," to be published in PNAS , redefines our understanding of how translation and post-transcriptional processes influence the body's internal clock and its impact on sleep patterns. (eurekalert.org)
  • And by trying to answer this basic timing question, we found that ribosomes bind an upstream open reading frame in Period2 which altered the amplitude of circadian rhythms and disrupted sleep in mice," adds lead author Arthur Millius. (eurekalert.org)
  • The researchers found many upstream open reading frames (uORFs) in the 5' untranslated region of circadian mRNAs, which is the part of RNA before the so-called "coding sequence" that gets translated by ribosomes into protein. (eurekalert.org)
  • Upstream open reading frames (uORFs) are important tissue-specific cis-regulators of protein translation. (johnshopkins.edu)
  • The genome of SARS-CoV is 29,727 nucleotides in length and has 11 open reading frames, and its genome organization is similar to that of other coronaviruses. (scienceopen.com)
  • Recent technological advances have revealed thousands of functional open reading frames (ORF) that have eluded reference genome annotations. (biomedcentral.com)
  • On the former, with the introduction of Next-Generation Sequencing techniques, reading one's genome has never been so reliable and affordable, still a fourth of Mendelian phenotypes remain without a known molecular basis ( www.omim.org/statistics ). (biomedcentral.com)
  • Yet, these annotations are used worldwide in fundamental and clinical research, providing the necessary dictionary to read a genome. (biomedcentral.com)
  • Therefore, we developed OpenVar ( https://openprot.org/openvar/ ), an open source tool to annotate and explore the impact of genomic variants using deeper genome annotations, such as OpenProt [ 3 ]. (biomedcentral.com)
  • Here we describe PLATO, an in vitro method for mapping such interactions by affinity enrichment of a library of full-length open reading frames displayed on ribosomes, followed by massively parallel analysis using DNA sequencing. (johnshopkins.edu)
  • A simple gene prediction algorithm for prokaryotes might look for a start codon followed by an open reading frame that is long enough to encode a typical protein, where the codon usage of that region matches the frequency characteristic for the given organism's coding regions. (wikipedia.org)
  • Analyses of the data in GenBank demonstrated a high degree of homology between the product of the 1,218-bp open reading frame, referred to as the adr-1 gene, and Ser (Thr) protein kinases. (psu.edu)
  • Open-reading frames corresponding to the predicted polymerase protein (polymerase 1a, 1b), spike protein (S), small membrane protein (E), membrane protein (M), and nucleocapsid protein (N), plus several other open-reading frames of unknown function, have been identified. (cdc.gov)
  • Kamal Niaz, Muhammad Farrukh Nisar , " Coronavirus Disease-19 (COVID-19): A Perspective of New Scenario ", Bentham Science Publishers (2021). (benthamscience.com)
  • The widespread applications of ribosome profiling and ribosome nascent chain complex sequencing revealed that some short open reading frames of lncRNAs have micropeptide-coding potential. (biomedcentral.com)
  • This Special Issue aims to discuss the role citizen science (CS) can play in monitoring and implementing the United Nations Sustainable Development Goals ( https://www.un.org/sustainabledevelopment/sustainable-development-goals/ ). (mdpi.com)
  • As an example, the Stockholm Environment Institute has stated in its discussion brief ( https://mediamanager.sei.org/documents/Publications/SEI-2017-PB-citizen-science-sdgs.pdf ) that citizen science can contribute to defining targets and metrics on different levels, monitoring progress and implementing action. (mdpi.com)
  • In the context of gene finding, the start-stop definition of an ORF therefore only applies to spliced mRNAs, not genomic DNA, since introns may contain stop codons and/or cause shifts between reading frames. (wikipedia.org)
  • By itself even a long open reading frame is not conclusive evidence for the presence of a gene. (wikipedia.org)
  • In order to verify whether the ferritin gene contributed to swimming crab salinity adaptation, ferritin (PtFer) cDNA open reading frame (ORF) was cloned. (trjfas.org)
  • Their simple modular structure and single open reading frame format are highly amenable to gene therapy-mediated delivery. (frontiersin.org)
  • The course is offered at the first-cycle level as a compulsory course within the Bachelor of Science in Development Studies with a major in Political Science. (lu.se)
  • The three tracks differ as specified below but all include compulsory readings and assignments. (lu.se)
  • The course is offered as a single subject course in sociology of law and is a compulsory course within the programme Master of Science in Sociology of Law - European Law (SELA). (lu.se)
  • The College of Computer, Mathematical and Physical Sciences will hold an Open House for admitted students March 25, 2010. (umd.edu)
  • The faculty, students and staff of the College of Computer, Mathematical and Physical Sciences are eager to answer your questions about our undergraduate programs and the many opportunities we provide. (umd.edu)
  • communicate results of learning and research processes within given time frames, both in writing and orally. (lu.se)
  • In other words, if we were to re-frame climate change in terms of localized impacts that people personally experience and can understand--such as vulnerability to extreme heat or poor air quality--could we shift public thinking on the issue? (scienceblogs.com)
  • In his appearance last week on NPR Science Friday (audio), Columbia University's Jeffrey Sachs framed the climate challenge not in terms of regulating pollution but rather as an energy and technology problem. (scienceblogs.com)
  • The Chicago based think tank seeks to frame climate change in a way that is consistent with their free market ideology and mission. (scienceblogs.com)
  • We are organising and participating in events on climate litigation, science and activism, and the role of the arts in the climate crisis. (lu.se)
  • Resumption of scanning leads to translation of downstream reading frames only if the necessary translation initiation factors are reacquired by the 40 s subunit before reaching the downstream start codon. (nature.com)
  • The disciplinary home of the research group is the intersection of International Relations and Peace Research broadly conceived, and we discuss and read theoretical as well as empirical work. (lu.se)
  • abg a Freie Universität Berlin, Department of Mathematics and Computer Science, Berlin, Germany. (rsc.org)
  • Vladimir Eidelman has been awarded the National Science Foundation Graduate Research Fellowship (NSF GRF) and the National Defense Science and Engineering Graduate Fellowship (NDSEG). (umd.edu)
  • The winners from Sweden will then compete in an International Mathematical and Science Creativity Competition in Seoul South Korea. (lu.se)
  • All articles published by MDPI are made immediately available worldwide under an open access license. (mdpi.com)
  • For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. (mdpi.com)
  • It may apply directly to our services.Open Access JournalsCloser to home is the recent announcement by the science and medical libraries of Yale University to discontinue their subsidy of author charges for BioMed Central journals. (dltj.org)
  • Bill is decidedly pro-Open Access -- as am I -- and we have a running discussion in the commentary of this posting on DLTJ. (dltj.org)
  • This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( http://creativecommons.org/licenses/by-nc/4.0/ ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. (kosinmedj.org)
  • Yet, sustainability is still often framed and understood through a growth paradigm. (lu.se)
  • Each biweekly issue offers a selective collection of Internet resources covering topics in the sciences, and related fields such as math and engineering, that have been chosen by librarians and content specialists in the given field of study. (wisc.edu)
  • The syllabus was approved by the board of the Department of Political Science on 2011-11-08 and was last revised on 2016-02-02. (lu.se)
  • For one part of this segment, as I have argued, you re-frame the issue as a moral and religious matter. (scienceblogs.com)
  • Reading - for education and for pleasure - may be framed as a personal indulgence, a moral virtue, or even a civic duty. (bepress.com)
  • The Divisional Fellow position that we are advertising (in Nature and Science, attached) is equivalent to a tenure-track faculty position at a university, and is appropriate for highly-qualified scientists with a Ph.D. or M.D. degree, who have completed post-doctoral training or equivalent experience. (blogspot.com)
  • A challenge to my readers and fellow science bloggers! (scienceblogs.com)
  • Harnessing computational principles to build systems that operate in the open world can also teach us about the sufficiency of existing models, and frame new directions for research. (umd.edu)
  • Usually, this is considered within a studied region of a prokaryotic DNA sequence, where only one of the six possible reading frames will be "open" (the "reading", however, refers to the RNA produced by transcription of the DNA and its subsequent interaction with the ribosome in translation). (wikipedia.org)
  • The ORF Finder (Open Reading Frame Finder) is a graphical analysis tool which finds all open reading frames of a selectable minimum size in a user's sequence or in a sequence already in the database. (wikipedia.org)
  • NIOSH researchers have developed several direct-reading methods and real-time monitors in recent years. (cdc.gov)
  • Read the full article here . (who.int)
  • The final option open to the students is to take a literature course. (lu.se)
  • Back in November, when Missouri passed a constitutional amendment protecting the ability of scientists to conduct embryonic stem cell research in the state, it was heralded as one more political victory for science, and a sign that even in the Midwest, proponents had turned the corner on conservative opposition. (scienceblogs.com)
  • Established in 2014, the Center's work on direct reading methodologies and sensors is based on decades of NIOSH research in this area. (cdc.gov)
  • design, execute and reflect on all stages of the research process within a predetermined time frame. (lu.se)
  • Ribosome-profiling has uncovered pervasive translation in non-canonical open reading frames, however the biological significance of this phenomenon remains unclear. (nature.com)
  • RÉSUMÉ Une analyse documentaire des informations publiques disponibles a été entreprise afin de passer en revue les connaissances et les lacunes actuelles sur le coronavirus du syndrome respiratoire du Moyen-Orient (MERS-CoV), notamment sur son origine, la transmission, les mesures de lutte efficaces et la prise en charge. (who.int)
  • Two blogs have been published on the selection of the right technology and its adoption in the frame of fatigue risk management plan. (cdc.gov)
  • The knowledgeable selection and adoption of direct-reading methodologies and sensors for health and safety is an aspect of great interest for the Center. (cdc.gov)
  • The Scout Report for Science & Engineering is also provided via email once every two weeks. (wisc.edu)
  • Direct reading technologies and devices using sensors play an important role in several activities of health and safety in the workplace including detecting the presence of a chemical or physical hazard, identifying a hazardous physical condition, evaluating the performance of work practices and engineering controls, and improving worker engagement via training and awareness. (cdc.gov)
  • Since 2012, the Center for Science and the Imagination at Arizona State University has worked on transdisciplinary projects to inspire collective imagination for better futures. (litsciarts.org)
  • This study sought to overcome methodological problems (e.g., sampling frame, lack of blinding) in the earlier pilot study. (cdc.gov)
  • It will be followed by a longer paper tomorrow, at which time this link will work and you will be able to read it. (scienceblogs.com)
  • Open the red and blue taps - one at a time. (lu.se)
  • In order to avoid crowding, please arrive and register during the time frame alotted to your group. (lu.se)
  • Please keep within the time frame of your group. (lu.se)
  • The National Institute for Occupational Safety and Health's (NIOSH) Center for Direct Reading and Sensor Technologies is the centralized hub for all things related to sensor and direct reading technology. (cdc.gov)
  • The first step towards the creation of the Center was the 2008 NIOSH Direct Reading Exposure Assessment Methods (DREAM) Workshop . (cdc.gov)