AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and ProcessesInformation ScienceNamed GroupsHealth Care
Oocyte DonationOocytesTissue DonorsOvulation InductionFertilization in VitroFollicle Stimulating Hormone, HumanDonor SelectionOvarian Hyperstimulation SyndromeInfertility, FemalePregnancy RateEmbryo TransferAttitudePregnancyGonadotropin-Releasing HormoneBlood DonorsLiving DonorsOogenesisOocyte RetrievalXenopus laevisMeiosisRetrospective StudiesIn Vitro Oocyte Maturation TechniquesXenopusMicroinjectionsFertilizationMetaphaseCumulus CellsBlastocystParthenogenesisCryopreservationOvumSperm-Ovum InteractionsOvaryEmbryonic DevelopmentSperm Injections, IntracytoplasmicSpermatozoaZona PellucidaMaturation-Promoting FactorZygoteNuclear Transfer TechniquesCleavage Stage, OvumEmbryo Culture TechniquesMolecular Sequence DataTissue and Organ HarvestingRNA, ComplementaryCells, CulturedTissue and Organ ProcurementEgg ProteinsRNA, MessengerFollicular FluidCytoplasm
SpermCryopreservationMaturationEggsFertilizationOvariesUltrasound-guided transvaginal oocyte reOvarianRetrievalImmature oocytesCyclesSomatic cellMetaphase II oocytesHuman oocytesBovine oocytesInfertileBlastocystsDonated cryopreservedFreezingRecipientsNucleusGenetically identicalReproductiveCost of donorOutcomesICSIPatient'sMeioticSCNT2000TissueNormal menstrual cycleFrozenVitrificationTransabdominalPotential donorsOutcomeVivoBlastocystMitochondrialOvaryPrimordialViableFertileOocystNuclear transferPregnancyPatientsSuccessfullySpindleGenetic diseaseFertility CenterUndergoRoutineMatureFreshProcedure
Sperm15
  • This study explores the attitudes and experiences of 57 sperm donors who responded to a survey posted online in the United States and indicated that they had had contact with their donor-conceived offspring or the parents of their donor-conceived offspring. (researchgate.net)
  • Donor coverage -- The plan will cover associated donor medical expenses, including collection and preparation of ovum and/or sperm, and the medications associated with the collection and preparation of ovum and/or sperm. (stryker.com)
  • Coverage is limited to: collection of sperm, cryopreservation of sperm, ovarian stimulation and retrieval of eggs, oocyte cryopreservation, InVitro fertilization, and embryo cryopreservation. (stryker.com)
  • This method is also sometimes employed when donor sperm is used. (wikipedia.org)
  • The oocytes (eggs) are removed from the donor and fertilized with sperm in the laboratory, then transferred to the recipient. (bcm.edu)
  • Whereas frozen eggs need to be thawed and fertilized with partner or donor sperm for use at a later date. (uvm.edu)
  • Kallen did add she's "never heard of a clinic requiring contact information for a potential father or sperm donor" and that such requirements sounded "intrusive and unnecessary" and "irrelevant to the decision to freeze eggs. (uvm.edu)
  • Lines are recovered using cryopreserved sperm and C57BL/6NTac oocyte donors. (taconic.com)
  • In terms of insemination, ICSI needs only one sperm cell per oocyte , while IVF needs 50,000-100,000. (wikipedia.org)
  • Resultant matured oocytes were fertilized by intracytoplasmic sperm injection (ICSI). (springer.com)
  • For assisted reproductive techniques, oocytes and sperm are collected from the intended parents or donors, and an embryo or the gametes are transferred to the woman's reproductive tract after culture in vitro. (msdmanuals.com)
  • The semen sample is typically washed several times with tissue culture medium and is concentrated for motile sperm, which are then added to the medium containing the oocytes. (msdmanuals.com)
  • At this point, intracytoplasmic sperm injection-injection of a single sperm into each oocyte-may be done, particularly if spermatogenesis is abnormal in the male partner. (msdmanuals.com)
  • After sperm are added, the oocytes are cultured for about 2 to 5 days. (msdmanuals.com)
  • 4. Use of sperm or oocyte donors. (who.int)
Cryopreservation6
  • Evidence-based outcomes after oocyte cryopreservation for donor oocyte in vitro fertilization and planned oocyte cryopreservation: a guideline. (guidelinecentral.com)
  • Improvements in oocyte cryopreservation techniques and establishment of cryopreserved donor oocyte banks have led to improved access to and lower cost of donor oocytes, upending the traditional practice of fresh oocyte donation. (biomedcentral.com)
  • Improved survival of human oocytes following cryopreservation via the vitrification technique prompted a change in the position of the American Society for Reproductive Medicine (ASRM) on the experimental nature of oocyte cryopreservation in 2013 [ 1 ]. (biomedcentral.com)
  • This conclusion was questioned by colleagues who argued that, as fertility centers gain expertise with oocyte cryopreservation and thawing, success rates would align with those of fresh oocytes [ 3 ]. (biomedcentral.com)
  • Oocyte cryopreservation (egg-freezing), Kallen explained, is when a woman's eggs are removed from the ovaries and stored for future use as "a way of preserving reproductive ability in women (or individuals with ovaries)" and an alternative for "anyone who isn't planning pregnancy immediately" but might want to explore their options in the future. (uvm.edu)
  • Another interesting topic that deserves attention is fertility preservation using oocyte cryopreservation. (pacificfertilitycenter.com)
Maturation8
  • We report the pregnancy and live birth achieved after in vitro maturation (IVM) of oocytes and PGT-A in a 23-year-old patient suffering from ovarian gonadotropin resistance. (springer.com)
  • Galvão A, Segers I, Smitz J, Tournaye H, De Vos M. In vitro maturation (IVM) of oocytes in patients with resistant ovary syndrome and in patients with repeated deficient oocyte maturation. (springer.com)
  • Successful somatic-cell nuclear transfer (SCNT) depends on the quality, availability and maturation of the animal's unfertilized oocytes. (nature.com)
  • 2. Owner agrees to pay ROOD AND RIDDLE EQUINE HOSPITAL $300 for maturation of an oocytes(s) per cycle, $600 per ICSI session for fertilization and embryo culture of fertilized oocyte(s), and $1,000 for each blastocyst produced for each IVF Cycle. (jotform.com)
  • Moreover, in spite of the early success of equine oocyte in vitro maturation [ 2 ], no relevant research on the issue has been reported in the horse for some time. (ivis.org)
  • After 8 days of stimulation, 10000 IU of human chorionic gonadotropin (Pregnyl, NV Organon, Oss, Netherlands) was administered for oocyte maturation. (hindawi.com)
  • In this work, we propose a new strategy to produce bovine parthenogenetic embryos inhibiting the emission of the first polar body during in vitro maturation, and allowing the extrusion of the second polar body during oocyte activation. (techscience.com)
  • In experiment 1, the effect of cytochalasin B on in vitro maturation of bovine oocytes was evaluated. (techscience.com)
Eggs20
  • Egg donation is the process by which a woman provides one or several (usually 10-15) eggs (ova, oocytes) for purposes of assisted reproduction or biomedical research. (ferty9.com)
  • We typically use fresh eggs and donors are stimulated once selected by a couple/patient. (ilaya.com)
  • The procedure typically involves a doctor removing an egg or eggs from the donor, fertilizing them in a laboratory, and then transferring the resulting embryos into the recipient's uterus. (medicalnewstoday.com)
  • The donor will then take a series of fertility drugs that stimulate the ovaries to produce several eggs at once. (medicalnewstoday.com)
  • Donors do have a risk of pregnancy before the eggs are retrieved, so it is a good idea to avoid intercourse or use a barrier contraceptive, such as a condom. (medicalnewstoday.com)
  • Shortly before the retrieval of the eggs, the donor will receive a final injection in preparation for the procedure. (medicalnewstoday.com)
  • The procedures and medications for egg donors are the same as they are for women using their own eggs in the IVF process and carry the same level of risk. (medicalnewstoday.com)
  • under age 55 and using donor oocytes (eggs). (stryker.com)
  • With oocyte donation, any woman with a healthy uterus, regardless of the condition of her own eggs, can potentially bear a child with her partner. (bcm.edu)
  • Between 2000 and 2010, the number of pregnancies using donor eggs increased, resulting in a greater number of healthy IVF births. (medicaldaily.com)
  • When donor eggs were used, the rate-13.1 percent-varied little with maternal age. (aafp.org)
  • A human female embryo develops around 7 million proto-eggs, known as primordial oocytes. (discovermagazine.com)
  • In the United States those voluntary donors receive several thousand dollars for each harvest of eggs, and it is hard-earned pay. (discovermagazine.com)
  • They must inject themselves daily for four weeks with large doses of hormones to encourage their ovaries to produce numerous mature oocytes while simultaneously suppressing the normal menstrual cycle, which would eject the eggs into the fallopian tubes. (discovermagazine.com)
  • By sharing donated eggs with one or two other recipients, you can share the cost of the donor, the most expensive part of treatment. (shadygrovefertility.com)
  • An analysis of more than 2,000 donor egg cycles at Shady Grove Fertility clearly demonstrated that the majority of egg donors will produce enough eggs to share with more than one recipient. (shadygrovefertility.com)
  • Donor eggs (or donor oocytes) include both fresh or frozen eggs. (valleyhealth.com)
  • Freezing eggs (or oocyte freezing) of young(ish) women to preserve fertility options is known as social egg freezing. (creatingafamily.org)
  • We discuss using frozen donor eggs from an egg bank in our section on egg donation . (creatingafamily.org)
  • Donor egg banks are reporting successful pregnancies with eggs frozen from women in their 20s, but most women wanting to freeze their own eggs for future use are in their late 30s. (creatingafamily.org)
Fertilization7
  • The oocyte from a donor can be either recovered as an embryo after it has undergone fertilization within the body (by uterine lavage (washing) in a process called ovum transfer) or recovered as an egg and inseminated in vitro (in the laboratory) to yield an in vitro fertilized embryo. (ferty9.com)
  • With ART, the process of sexual intercourse is bypassed and fertilization of the oocytes occurs in the laboratory environment (i.e., in vitro fertilization ). (wikipedia.org)
  • Round spermatid injection (ROSI) is a technique of assisted reproduction whereby a round spermatid is injected into oocyte cytoplasm in order to achieve fertilization. (wikipedia.org)
  • The results suggest that oocytes obtained with IVM in patients with ROS are capable of meiotic and mitotic division, fertilization, and generation of euploid embryos. (springer.com)
  • In vitro fertilization with donor oocytes and embryo transfer is the most common treatment modality. (wikidoc.org)
  • Ovarian tissue cryobanking and immature oocyte collection followed by fertilization of matured oocytes is another promising approach. (wikidoc.org)
  • Each month, highly coordinated hormonal and ovarian morphological changes develop and release a mature oocyte that is ready for fertilization. (medscape.com)
Ovaries3
  • Poor ovarian reserve is a condition of low fertility characterized by 1): low numbers of remaining oocytes in the ovaries or 2) possibly impaired preantral oocyte development or recruitment. (wikipedia.org)
  • First, they extract immature, unfertilised egg cells called oocytes from the ovaries of ewes. (newscientist.com)
  • Said oocyte recovery from harvested ovaries will be charged at routine cost. (jotform.com)
Ultrasound-guided transvaginal oocyte re2
  • Without gonadotropin priming and HCG trigger, ultrasound-guided transvaginal oocyte retrieval was performed. (springer.com)
  • We report for the first time a case of ureteral injury that presented with delayed massive hematuria without urinary tract signs of peritoneal irritation 4 and 6 days after ultrasound-guided transvaginal oocyte retrieval. (hindawi.com)
Ovarian3
  • Ovarian reserve tests can be used to estimate the anticipated oocyte yield. (guidelinecentral.com)
  • Most clinical IVF programs offer in parallel autologous programs, which utilize the patients' own oocytes, and programs, which utilize oocytes from mostly young oocyte donors, usually under age 30 years, and with normal ovarian reserve. (biomedcentral.com)
  • In contrast to autologous IVF cycles, donor oocyte cycles, therefore, reflect fewer covariates, as age and ovarian reserve of oocyte donors can be assumed to be quite uniform between centers, while still maintaining the important variability of clinical cycle management and IVF laboratory performance, both very basic quality parameters for IVF centers. (biomedcentral.com)
Retrieval13
Immature oocytes1
Cycles8
  • Title : Trends and Outcomes for Donor Oocyte Cycles in the United States, 2000-2010 Personal Author(s) : Kawwass, Jennifer F.;Monsour, Michael;Crawford, Sara;Kissin, Dmitry M.;Session, Donna R.;Kulkarni, Aniket D.;Jamieson, Denise J. (cdc.gov)
  • A retrospective analysis of 2013 through 2015 aggregate U.S. national data reported by the Society for Assisted Reproductive Technology which included 30,160 IVF cycles with either fresh or cryopreserved donor oocytes was performed. (biomedcentral.com)
  • The main outcome measure was correlation between center-specific live birth rates (LBR) in autologous and donor oocyte cycles. (biomedcentral.com)
  • Since center-specific donor and autologous IVF cycle outcomes correlate, and as donor cycles reflect fewer patient covariates, they represent a first comparable performance measure between centers, allowing for internal as well as external quality control. (biomedcentral.com)
  • In a first step, attempting to establish a model to compare performance criteria between IVF centers we assessed whether in individual programs center-specific live birth rates (LBR) in donor oocyte cycles, in principle, correlate with center-specific LBR in autologous IVF cycles. (biomedcentral.com)
  • We reviewed center-specific outcome data from U.S. National Assisted Reproductive Technology Surveillance System (NASS) reported by 451 centers for IVF cycles initiated in 2011 (non-donor and donor oocytes), which progressed to fresh embryo transfers [ 1 ]. (biomedcentral.com)
  • Only clinics performing more than 20 fresh transfers from autologous oocytes per age group in women up to age 40 and more than 20 fresh oocyte donation cycles were included in order to focus on statistically meaningful LBR data. (biomedcentral.com)
  • A 5-10% live birth rate per oocyte in women under the age of 35 years translates to a respectable chance of having a baby in the future from one to two treatment cycles in the present (10-20 oocytes can be expected to be cryopreserved per cycle). (pacificfertilitycenter.com)
Somatic cell2
  • The single cell line generated in the 2004 Science paper resulted from nuclear transfer in which the oocyte and non-reproductive ("somatic") cell came from the same healthy female. (scienceblog.com)
  • if it implants and the pregnancy goes to term, the resulting individual will carry the same nuclear genetic material as the donor of the adult somatic cell. (who.int)
Metaphase II oocytes2
  • The cloning method is based on the fact that cytoplasmic factors in mature, metaphase II oocytes are able to reset the identity of a transplanted adult cell nucleus to an embryonic state. (news-medical.net)
  • Experimental spindle transfer in metaphase II oocytes, also called mitochondrial replacement therapy, is a novel technology for preventing mtDNA transmission from oocytes to pre-implantation embryos. (infertile.com)
Human oocytes2
  • The adult cell nuclei were transferred into metaphase-II stage human oocytes, producing a karyotypically normal diploid embryonic stem cell line from each of the adult male donor cells. (news-medical.net)
  • The therapeutic potential of cloned human cells has been demonstrated by another study using human oocytes to reprogram adult cells of a type 1 diabetic. (news-medical.net)
Bovine oocytes1
  • Previously, intra- and interspecific canine embryos have been constructed by canine SCNT into canine and bovine oocytes, respectively, but this did not result in viable offspring 9 . (nature.com)
Infertile3
  • Are euploidy rates different in blastocysts from donor oocytes and those from young infertile patients? (scrcivf.com)
  • Infertile women should be counseled that, based on a small number of births, neonatal outcomes appear similar after using their own previously cryopreserved oocytes compared with outcomes after the use of fresh oocytes. (guidelinecentral.com)
  • Ovum transfer, the transfer of a normally fertilized egg from a female donor to an infertile recipient. (ferty9.com)
Blastocysts2
  • From the 185 donated oocytes, endowed with the genetic material from a different person (or in one case, the same person), the researchers report development of 31 hollow balls of cells called "human nuclear-transfer blastocysts. (scienceblog.com)
  • ROOD AND RIDDLE EQUINE HOSPITAL shall mature the oocytes, evaluate them and, if presumably mature, fertilize it (them) via ICSI in an attempt to produce viable embryos (blastocysts). (jotform.com)
Donated cryopreserved1
  • Though ASRM recommended against routine donor oocyte banking until more robust clinical data on safety and efficacy of cryopreserved donor oocytes were generated, multiple commercial cryopreserved oocyte donor banks were nevertheless concurrently established in the U.S. Based on 2013 U.S. national data, we previously reported that live birth rates for recipients of donated cryopreserved oocytes were lower than those of fresh oocytes [ 2 ]. (biomedcentral.com)
Freezing2
  • Conceiving, even at a slightly later age with higher success rate, is possible with Oocyte Freezing or Egg Freezing. (artbabyeggdonors.com)
  • As we further perfect our own techniques of vitrification, we will be increasingly more confident in our ability to offer young women with a viable option for future family planning in addition to embryo freezing and donor gametes. (pacificfertilitycenter.com)
Recipients8
  • It is recommended to tell recipients that previously cryopreserved donor oocytes are a reasonable option compared with fresh donor oocytes, given that there is good evidence that there are no significant differences in per transfer pregnancy rates compared with those with fresh donor oocytes. (guidelinecentral.com)
  • Recipients can be counseled that as the number of donor oocytes warmed increases, there is an associated increase in cumulative live birth rate. (guidelinecentral.com)
  • Recipients can be counseled that live birth rates may be greater from vitrified oocytes that derive from donors who had prior successful outcome after a fresh cycle of oocyte donation. (guidelinecentral.com)
  • Recipients can be counseled that the length of time that oocytes have been stored is not associated with differences in oocyte survival or pregnancy rates. (guidelinecentral.com)
  • Recipients can be counseled that, based on limited evidence, neonatal outcomes appear similar between vitrified and fresh donor oocytes. (guidelinecentral.com)
  • Treatment with a new class of drugs, called senolytics, in donors improved the physical fitness of the recipients, a new study has shown. (medicaldaily.com)
  • We collected an average of 12 oocytes from each female, and a total of 1,095 reconstructed canine embryos were transferred into 123 recipients. (nature.com)
  • Donors are selected based on the principles that their health will not be compromised in the process, and the donated materials, such as TISSUES or organs, are safe for reuse in the recipients. (bvsalud.org)
Nucleus4
  • The bound complex is internalized and translocates into the oocyte nucleus thanks to an SV40 nuclear localization signal, enhanced by an adjacent casein kinase phosphorylation site. (biologists.com)
  • Each of the 11 new human embryonic stem cell lines was created by transferring the nuclear genetic material from a non-reproductive cell of a patient into a donated egg, or "oocyte," whose nucleus had been removed. (scienceblog.com)
  • However, an animal created through this technique would not be a precise genetic copy of the source of its nuclear DNA because each clone derives a small amount of its DNA from the mitochondria of the egg (which lie outside the nucleus) rather than from the donor of cell nucleus. (who.int)
  • Thus, the clone would be genetically identical to the nucleus donor only if the egg came from the same donor or from her maternal line. (who.int)
Genetically identical4
  • By transferring adult cell DNA into an embryonic stem cell, it is possible to create a line of immortal embryonic cells that are able to develop into any type of adult cell, genetically identical to the donor. (news-medical.net)
  • Snuppy is genetically identical to the donor Afghan hound. (nature.com)
  • We tested whether the cloned dogs were genetically identical by microsatellite analysis of genomic DNA from the donor Afghan, the cloned dogs and the surrogates (see supplementary information ). (nature.com)
  • Analysis of eight canine-specific microsatellite loci confirmed that the cloned dogs were genetically identical to their donor dog. (nature.com)
Reproductive4
  • Oocyte Donor Program:The use of the female gamete, the egg or oocyte, for the treatment of certain disorders leading to female reproductive failure has only been possible since 1984. (ferty9.com)
  • Transnational reproductive travel is symptomatic of insufficient supplies of reproductive resources, including donor gametes and gestational surrogacy services, and inequities in access to these within domestic health-care jurisdictions. (researchgate.net)
  • Oocyte donors and patients who donated non-reproductive cells were all unpaid volunteers. (scienceblog.com)
  • For underage donors of non-reproductive cells, both parents signed informed-consent agreements. (scienceblog.com)
Cost of donor1
  • It can reduce the cost of donor egg treatment by up to 50 percent and can be combined with our Shared Risk 100% Refund Program for Donor Egg. (shadygrovefertility.com)
Outcomes2
  • Neonatal outcomes appear similar with cryopreserved oocytes. (guidelinecentral.com)
  • In a Science "Policy Forum" related to the team's latest findings, David Magnus and Mildred Cho from Stanford University in Palo Alto, CA discuss international oversight and ethical issues in oocyte donation, including the need to promote realistic expectations of the outcomes of stem cell research. (scienceblog.com)
ICSI2
  • [2] The microinjection procedure for ROSI also differs slightly from that of ICSI, since additional stimuli are needed to ensure proper oocyte activation after spermatid injection. (wikipedia.org)
  • ICSI produced the first pregnancy derived from an in vitro matured oocyte [ 5 ], and it was successfully carried to term. (ivis.org)
Patient's2
Meiotic2
  • Unlike other mammals, dogs ovulate at first meiotic prophase, and their oocytes mature for 2 to 3 days in the oviduct's distal regions. (nature.com)
  • Most oocytes (77%) were arrested at a meiotic stage characterized by the presence of a large internal metaphase plate and absence of polar body. (techscience.com)
SCNT2
  • In 2013, scientists reported a successful SCNT procedure by modifying the protocol for specific human oocyte biology. (news-medical.net)
  • For SCNT, the chromosomes of the unfertilized canine oocytes were removed by micromanipulation, and a single donor cell was transferred into each enucleated oocyte. (nature.com)
20001
Tissue2
  • Avoiding transfusions from family members is important because of possible sensitization against non-HLA (human leukocyte antigen) tissue antigens of potential donors. (medscape.com)
  • Recent news of an impending clinical cell transplantation trial in Parkinson's disease using parthenogenetic stem cells as a source of donor tissue have raised hopes in the patient community and sparked discussion in the research community. (lu.se)
Normal menstrual cycle1
  • Before starting the procedure, most donors will need to take medication that stops their normal menstrual cycle. (medicalnewstoday.com)
Frozen1
Vitrification2
  • The other presentation by a group in New York reported their experience of rewarming 536 cryopreserved oocytes using both slow freeze and vitrification from non-donors with an average age of 32 years. (pacificfertilitycenter.com)
  • PFC s own data with vitrification of oocytes is comparable to, if not better than, the results presented at our national meeting by various groups across the US. (pacificfertilitycenter.com)
Transabdominal1
  • Today, the most practical use of OPU or transabdominal follicle aspiration is to recover in vivo matured oocytes [ 9 ] for oocyte transfer. (ivis.org)
Potential donors1
  • The procedure established to evaluate the health status and risk factors of the potential DONORS of biological materials. (bvsalud.org)
Outcome1
  • To test this hypothesis, we here report two additional years of national outcome data that have become available since our original publication, demonstrating that the par between fresh and cryopreserved oocyte over these 2 years has actually significantly widened. (biomedcentral.com)
Vivo2
  • Here we describe the cloning of two Afghan hounds by nuclear transfer from adult skin cells into oocytes that had matured in vivo . (nature.com)
  • We collected oocytes matured in vivo at metaphase II about 72 hours after ovulation by flushing the oviducts. (nature.com)
Blastocyst2
  • If by December 31, 2023, no blastocyst is produced from the Donor Mare, ROOD AND RIDDLE EQUINE HOSPITAL or Owner shall have the right to declare this Contract terminated. (jotform.com)
  • A male euploid blastocyst was obtained from the reconstituted oocytes, which had only a 5.7% mtDNA mutation load. (infertile.com)
Mitochondrial1
  • The mitochondrial DNA of the stem cells, however, matched the donor egg's mitochondrial DNA. (news-medical.net)
Ovary2
  • Injected intravenously into adult Xenopus females, the protein-DNA complex is rapidly transported through the bloodstream and, within the ovary, the vitellogenin ligand present in the protein binds to the receptors at the surface of the oocytes. (biologists.com)
  • As the oocyte matures in the postnatal mammalian ovary during folliculogenesis it increases exponentially in volume, and the oocyte mitochondria population proliferates to about 100 000 mitochondria per healthy, mature murine oocyte. (cdc.gov)
Primordial1
  • Oocyte mitochondria are unique organelles that establish a founder population in primordial germ cells (PGCs). (cdc.gov)
Viable1
Fertile3
  • Use of oocytes from anonymous, matched, fertile donors for prevention of heritable genetic diseases. (bmj.com)
  • We report our experience in using donor oocytes from anonymous, matched, fertile donors in four women with heritable genetic disorders. (bmj.com)
  • Egg donation is a process in which a fertile woman donates an egg, or oocyte, to another woman to help her conceive. (medicalnewstoday.com)
Oocyst2
  • Wilmut says there were so many failures because it is difficult to ensure that the empty oocyst and the donor cell are at the same stage of the cell division cycle. (newscientist.com)
  • We investigated prevalence of antibodies against the 27-kDa Cryptosporidium oocyst antigen among blood donors in 2 areas of Scotland supplied by drinking water from different sources with different filtration standards: Glasgow (not filtered) and Dundee (filtered). (cdc.gov)
Nuclear transfer3
  • The ten additional new lines resulted from nuclear transfer with skin cells of males or females and oocytes from biologically-unrelated females. (scienceblog.com)
  • Pregnancy was established only after embryo transfer of very-early-stage nuclear-transfer constructs (that is, less than 4 hours after oocyte activation). (nature.com)
  • 2. Nuclear transfer is a technique used to duplicate genetic material by creating an embryo through the transfer and fusion of a diploid cell in an enucleated female oocyte.2 Cloning has a broader meaning than nuclear transfer as it also involves gene replication and natural or induced embryo splitting (see Annex 1). (who.int)
Pregnancy3
  • There are no significant differences in per transfer pregnancy rates with cryopreserved vs. fresh donor oocytes. (guidelinecentral.com)
  • If all requirements for round spermatid selection and injection are successfully met, the injected oocytes develop to early embryos and can be transferred to the mother's uterus to produce pregnancy. (wikipedia.org)
  • G), with a long history of multiple undiagnosed pregnancy losses and deaths of offspring as a result of this disease, who underwent IVF after reconstitution of her oocytes by spindle transfer into the cytoplasm of enucleated donor oocytes. (infertile.com)
Patients7
  • There is insufficient evidence to counsel patients regarding the likelihood of the long-term use of oocytes cryopreserved for planned OC. (guidelinecentral.com)
  • Despite rising popularity of cryopreserved donor oocytes, prospective patients should be counselled that fresh donor oocytes still represent standard of care due to higher live birth rates. (biomedcentral.com)
  • In their new paper, Science author Woo Suk Hwang from Seoul National University in Seoul, Korea and colleagues replaced the nuclei from donated oocytes with nuclei from skin cells from male and female patients, ranging in age from 2 to 56, who had spinal cord injuries, juvenile diabetes and the genetic disease "congenital hypogamma-globulinemia. (scienceblog.com)
  • The authors conclude that spontaneous abortion rates in patients using ART and their own oocytes and freshly fertilized embryos were slightly lower than the expected spontaneous abortion rate in women of comparable age. (aafp.org)
  • Each year hundreds of patients from Canada travel to Shady Grove Fertility for donor egg treatment. (shadygrovefertility.com)
  • The Shared Donor Egg Program was also developed to make treatment even more affordable for our patients. (shadygrovefertility.com)
  • We are well-practiced in synchronizing each recipient's treatment cycle with the donor, without compromising our patients' chances for success. (shadygrovefertility.com)
Successfully1
  • In those men in whom spermatogenesis is blocked at the stage of round spermatids, in which meiosis has already been completed, these round cells can successfully fertilize oocytes after being injected into their cytoplasm. (wikipedia.org)
Spindle2
  • Those were spindle removal, donor cell fusion, and cytoplast activation. (news-medical.net)
  • D) transfer of the removed spindle into the perivitelline space of the enucleated donor oocyte. (infertile.com)
Genetic disease1
  • Oocyte donation is also an option for those who are carriers of genetic diseases and wish to prevent the risk of either conceiving a child affected with the disease or who might be a carrier of a genetic disease. (bcm.edu)
Fertility Center1
  • The Valley Fertility Center coordinates donor egg services as an option for people who wish to become pregnant. (valleyhealth.com)
Undergo2
  • Throughout the donation cycle, a donor will undergo frequent blood tests and ultrasound examinations to monitor their reactions to the medications. (medicalnewstoday.com)
  • Donors must regularly undergo ultrasound and blood tests to monitor their developing oocytes. (discovermagazine.com)
Routine1
  • Said oocyte recovery will be charged at routine cost. (jotform.com)
Mature3
Fresh4
  • The objective of this study was to examine national trends in utilization and live birth rates with fresh versus cryopreserved donor oocytes. (biomedcentral.com)
  • Over the three-year study period fresh donor oocytes produced stable live birth rates per recipient cycle start while those with cryopreserved oocytes significantly declined year-by-year. (biomedcentral.com)
  • Figure 1 demonstrates that live birth rates per recipient cycle start were higher with fresh donor oocytes in each of the studied years. (biomedcentral.com)
  • 20 fresh oocyte donor transfers. (biomedcentral.com)
Procedure4
  • In this article, we look at the criteria for selecting donors, the procedure itself, and legal ramifications following an egg donation. (medicalnewstoday.com)
  • During the procedure, which lasts around 30 minutes, the doctor might give the donor painkillers, sedatives, or an anesthetic. (medicalnewstoday.com)
  • As this is a minor procedure, a donor will not need to stay at the clinic or hospital overnight. (medicalnewstoday.com)
  • The procedure can be undertaken at virtually any time because the rate limiting issue is the age of the oocyte donor. (bcm.edu)