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  • pregnancy rate
  • Now the investigators can previously cryopreserved donor oocytes and at the time that the investigators have a compatible receiver, then, plan the donation In this study it will be possible compare the results of oocyte donation cycles in terms of pregnancy rate, implantation and liveborn, depending on whether the recipient has made an artificial cycle of preparation endometrial or a natural cycle. (clinicaltrials.gov)
  • pathway
  • Cheon B, Lee HC, Wakai T, Fissore RA (2013) Ca 2+ influx and the store-operated Ca 2+ entry pathway undergo regulation during mouse oocyte maturation. (springer.com)
  • Addition of glucose-6-phosphate (G6P) or other intermediates in the pentose-phosphate pathway, but not the glycolytic pathway, inhibited activation of caspase-2 and caspase-3, cytochrome c release, and oocyte cell death. (sciencemag.org)
  • Inhibition of G6P dehydrogenase by dehydroisoandrosterone (DHEA), which inhibits the pentose-phosphate pathway, promoted oocyte cell death, increased the rate at which caspase activity rose in the egg extracts, and decreased the concentration of G6P and NADPH production. (sciencemag.org)
  • Thus, these results define a path from metabolic status through the pentose-phosphate pathway that controls oocyte cell survival in a process that relies on the phosphorylation state of caspase-2. (sciencemag.org)
  • embryonic stem
  • Frozen-thawed oocytes could be also later used for producing live offspring for faster multiplication of superior germplasm or for use in reproductive technologies like production of cloned or transgenic livestock or production of embryonic stem cells. (springer.com)
  • This restricts not only certain assisted reproduction procedures in IVF clinics where recipients wait for oocytes from donors, but also development of some promising approaches, like therapeutic nuclear transfer with subsequent derivation of patient compatible embryonic stem cells. (nih.gov)
  • vitro
  • Al-Hasani S, Kirsch J, Diedrich K, Blanke S, Van der Ven H, Krebs D (1989) Successful embryo transfer of cryopreserved and in vitro fertilized rabbit oocytes. (springer.com)
  • Fuku E, Kojima T, Shioya Y, Marcus GJ, Downey BR (1992) In vitro fertilization and development of frozen-thawed bovine oocytes. (springer.com)
  • Gautam SK, Verma V, Palta P, Chauhan MS, Manik RS (2008) Effect of type of cryoprotectant on morphology and developmental competence of in vitro-matured buffalo ( Bubalus bubalis ) oocytes subjected to slow freezing or vitrification. (springer.com)
  • Melatonin improves oocyte maturation and mitochondrial functions by reducing bisphenol A-derived superoxide in porcine oocytes in vitro. (greenmedinfo.com)
  • immature
  • Rather than rely on daily ultrasound tests and injections of fertility medicine, the new technique, immature oocyte retrieval and maturation, removes the egg from the ovary for fertilization and then places it back in the mother, says Gleicher. (thefreedictionary.com)
  • Russell and his colleagues at the Reproductive Endocrine and Fertility Center of Delaware in Newark, say the technique, called immature oocyte retrieval , promises to reduce the risks, costs, and discomforts of IVF. (thefreedictionary.com)
  • prophase
  • Meiotic resumption from the prophase of MI is morphologically characterized by the dissolution of the oocyte nuclear envelope, which is generally termed the "germinal vesicle breakdown" (GVBD). (springer.com)
  • fertilization
  • These data, the data in egg donors, and data from a recent meta-analysis ( 12 ) suggest that specific outcomes of IVF and ICSI (fertilization and pregnancy rates) are similar between fresh oocytes and vitrified oocytes. (acog.org)
  • Collectively, studies provide good evidence that fertilization and pregnancy rates using vitrified oocytes are similar to fresh IVF cycles or fresh ICSI cycles and are consistent with clinical experience with respect to the effect of the age of the oocyte when frozen or vitrified. (acog.org)
  • In the hours preceding fertilization, oocytes prepare to begin development in a process known as maturation. (springer.com)
  • Oocytes, the female germ cells, contain all the messenger RNAs necessary to start a new life but typically wait until fertilization to begin development. (sciencemag.org)
  • zygote
  • How to repair the oocyte and zygote? (nih.gov)
  • The transition from oocyte to fertilized egg (zygote) involves many changes, including protein synthesis, protein and RNA degradation, and organelle remodeling. (sciencemag.org)
  • cyclin
  • The key activity driving meiotic progression is the MPF (maturation-promoting factor), a heterodimer of CDC2 (cell division cycle 2 kinase) and cyclin B. In PI-arrested oocytes, MPF is initially inactive and is activated by the dual-specificity CDC25C phosphatase as the result of new synthesis of Mos induced by progesterone. (genome.jp)
  • Thus
  • Thus, the potential to combine these approaches by identifying the crucial factors in oocytes that mediate SCNT efficiency is reviewed in a new article published in Stem Cells and Development , a peer-reviewed journal from Mary Ann Liebert, Inc., publishers . (news-medical.net)
  • mechanisms
  • Chiba K, Kado RT, Jaffe LA (1990) Development of calcium release mechanisms during starfish oocyte maturation. (springer.com)
  • Kisspeptins are key central regulators of the neuroendocrine mechanisms of human reproduction, who have been shown to effectively elicit an LH surge and to induce final oocyte maturation in IVF cycles. (hindawi.com)
  • retrieval
  • GnRHa triggering elicits a surge of gonadotropins resembling the natural midcycle surge of gonadotropins, without the prolonged action of hCG, resulting in the retrieval of more mature oocytes and a significant reduction in or elimination of OHSS as compared to hCG triggering. (hindawi.com)
  • For each cycle, men whose female partner was undergoing IVF or IUI provided one spot urine sample at the time of oocyte retrieval or insemination, respectively. (thefreedictionary.com)
  • From a medical standpoint, this case of postmortem oocyte retrieval is fraught with difficulty. (thefreedictionary.com)
  • Comparison of different transvaginal ovum pick-up protocols to optimise oocyte retrieval and embryo production over a 10-week period in cows. (thefreedictionary.com)
  • Additionally, it avoids ethical concerns regarding ovarian stimulation and oocyte retrieval in children. (thefreedictionary.com)
  • The drops were prepared in Falcon #3002 Petri dishes (Becton-Dickinson Labware, Lincoln Park, NJ) one to three hours prior to oocyte retrieval with media that were equilibrated overnight in a 36. (thefreedictionary.com)
  • Women who underwent oocyte retrieval at our institution between August 1995 and February 1997 and agreed to participate in the study were enrolled consecutively. (thefreedictionary.com)
  • Table 1 gives an overview of the mean number of days of stimulation, the mean of the total number of ampoules of FSH used during the stimulation, the mean of the final E2 concentrations before oocyte retrieval , and the mean of the daily percent E2 increase. (thefreedictionary.com)
  • cycles
  • Outcomes of four published randomized controlled trials demonstrated that fresh and frozen oocytes yield similar pregnancy rates in IVF cycles, supporting the use of these technologies in well-selected patients aged 35 years and younger ( 8-11 ). (acog.org)
  • outcomes
  • Both clinical trials and observational studies have compared reproductive outcomes after IVF and intracytoplasmic sperm injection (ICSI) with cryopreserved oocytes to IVF and ICSI with fresh oocytes. (acog.org)
  • RNAs
  • Subsequently, 15 cystocytes begin to transport specific RNAs and other components into the remaining cell, the future oocyte. (nih.gov)
  • frozen
  • Several studies have indicated that a more advanced age of the oocyte when frozen or vitrified reduces the odds of success when vitrified oocytes are used for IVF or ICSI. (acog.org)
  • The announcement by Apple and Facebook that they would pay for their employees to place oocytes in frozen storage--so-called social freezing--sparked a heated debate about the creation of such a fertility resource for non-medical reasons. (eurekalert.org)
  • evident
  • For this reason, an increased effort to determine how to repair oocytes is evident in the literature. (nih.gov)
  • eggs
  • Oocyte death ultimately leads to sterility as the animals age and conditions that accelerate death of the eggs cause premature infertility. (sciencemag.org)
  • cell
  • In the present article, we will briefly outline the current methodological approaches that can be used to repair the oocyte or one-cell stage embryo. (nih.gov)
  • reproductive
  • A woman's reproductive life span is finite and depends on the number of oocytes with which she is born ( 2 , 3 ). (acog.org)