• Once sedation or anesthesia begins, they'll stay with you the entire time to monitor your breathing and other vital signs and your comfort level. (asda.org)
  • This narrative review describes the main applications of de la ultrasonografía en ultrasound in anesthesia, ultrasound-guided techniques, and current trends in the perioperative anesthetic management of anestesia the surgical patient. (bvsalud.org)
  • May cause postoperative agitation during emergence from anesthesia in children. (nih.gov)
  • We hypothesize that electroacupuncture at distal-proximal and regional acupoints prior to OP-CABG will reduce the dosage of anesthesia required during OP-CABG, and minimize postoperative complications. (clinicaltdd.com)
  • Secondary outcomes are cardiac troponin I content, inotropic score, dose of propofol used for anesthesia, duration of mechanical ventilation, duration of stay in the intensive care unit, length of postoperative hospital stay, incidence of overall complications within 30 days of surgery, and incidence of overall mortality within 30 days of surgery. (clinicaltdd.com)
  • Emergence times are generally short following sevoflurane anesthesia. (medicines.org.uk)
  • Patients treated with dexmedetomidine had better quality and more extended postoperative analgesia but longer postoperative anesthesia recovery and higher postoperative sedation scores when compared with remifentanil. (springeropen.com)
  • Each of these conditions puts the brain at risk of cerebral ischemia or ischemic stroke. (medscape.com)
  • Cerebral vascular insufficiency, typically caused by extracranial or intracranial steno-occlusive disease (any arterial occlusion or severe extracranial or intracranial stenosis in symptomatic arterial territory), is the leading cause of ischemic stroke . (medscape.com)
  • People who are suffering an ischemic stroke may be able to receive a clot-busting drug called tissue plasminogen activator (tPA) to dissolve the clot if they reach a hospital within 3 to 4.5 hours of symptom onset. (adam.com)
  • Nonetheless, the post-transplant course is often marked by complications that threaten both the quality and duration of the recipient's life. (ersjournals.com)
  • While offering a vital therapeutic option for patients with advanced lung disease, LTx remains fraught with complications that threaten both the quality and duration of the recipient's life. (ersjournals.com)
  • This trial protocol will determine whether acupuncture at distal-proximal or regional acupoints can reduce anesthetic dose and postoperative complications in OP-CABG surgery, with the purpose of ensuring patient safety in the perioperative phase. (clinicaltdd.com)
  • It is well known in the literature that having several chronic diseases impacts people's lives in several ways, such as the quality of life, psychological difficulties, higher mortality but also longer hospital stays, higher treatment costs, and more postoperative complications. (biomedcentral.com)
  • Transient global cerebral ischemia, such as that which occurs during cardiac arrest and resuscitation, is a major cause of serious neurologic morbidity. (silverchair.com)
  • METHODS: The authors conducted a retrospective cohort study of all consecutive patients younger than 18 years of age at the time of recommendation for invasive evaluation with SEEG who were treated from July 2009 to June 2020. (bvsalud.org)
  • METHODS: We evaluated patients with ES from the CDKL5 Centers of Excellence and the National Infantile Spasms Consortium (NISC), with onset from 2 months to 2 years, treated with adrenocorticotropic hormone (ACTH), oral corticosteroids, vigabatrin, and/or the ketogenic diet. (bvsalud.org)
  • Experimentally inducing SE by diverse methods is sufficient to induce late onset TLE in species ranging from rodents to nonhuman primates ( Pitkänen, 2010 ). (jneurosci.org)
  • The aim of this study was to investigate whether preoperative NT-proBNP can predict postoperative New York Heart Association (NYHA) functional class and hospital readmission in addition to morbidity and mortality. (limkinase-signal.com)
  • Postoperative functional class, morbidity, and hospital readmission were obtained through telephone interviews. (limkinase-signal.com)
  • Cerebral edema is a major cause of brain damage and contributes significantly to the mortality of ischemic strokes and traumatic brain injuries. (wikipedia.org)
  • No significant side effects or increase in postoperative mortality or morbidities were observed with iNO treatment. (biomedcentral.com)
  • Hypoxemia prolongs postoperative mechanical ventilation and intensive care unit (ICU) stay and increases postoperative mortality. (biomedcentral.com)
  • To accomplish this goal, cardiopulmonary bypass (CPB), often coupled with either deep hypothermic circulatory arrest (DHCA) or antegrade cerebral perfusion (ACP), is usually required. (medscape.com)
  • An ideal hypotensive agent can achieve the desired level of controlled hypotension with rapid onset, rapid offset, without affecting vital organ perfusion and without toxic metabolites (Standing et al. (springeropen.com)
  • The extent and severity of the symptoms of cerebral edema depend on the exact etiology but are generally related to an acute increase of the pressure within the skull. (wikipedia.org)
  • Acute invasive fungal rhinosinusitis (AIFRS) is defined by a time course of less than 4 weeks' duration, with predominant vascular invasion. (actaitalica.it)
  • Postoperative hypoxemia in acute type A aortic dissection (AADA) is a common complication and is associated with negative outcomes. (biomedcentral.com)
  • The incidence of this disorder should be considered in terms of its potential causes and is present in most cases of traumatic brain injury, central nervous system tumors, brain ischemia, and intracerebral hemorrhage. (wikipedia.org)
  • Those with left sided obstructive lesions, such as coarctation of the aorta, have an increased risk of cerebral hemorrhage. (medscape.com)
  • As the skull is a fixed and inelastic space, the accumulation of cerebral edema can displace and compress vital brain tissue, cerebral spinal fluid, and blood vessels, according to the Monro-Kellie doctrine. (wikipedia.org)
  • A sample of cerebral spinal fluid in those subjects demonstrated increased levels of dynorphin A. (medscape.com)
  • These data show that nimesulide protects against permanent focal cerebral ischemia, even with a 2 h post-treatment delay. (biomedcentral.com)
  • Many centers are switching to normothermic CPB because of shorter CPB and operating room times and improved myocardial protection. (asahq.org)
  • This simple classification helps guide medical decision making and treatment of patients affected with cerebral edema. (wikipedia.org)
  • They concluded that cerebral revascularization may be done safely at high-volume cerebrovascular centers for high-risk patients for whom optimal medical therapy has failed, and that further research must be done to develop an improved method of risk stratification for patients with symptomatic atherosclerotic cerebrovascular steno-occlusive disease to determine which patients may benefit from intervention. (medscape.com)
  • Transplantation of patients with underlying cystic fibrosis (CF), whose native airways and sinuses are chronically infected with virulent bacterial pathogens, initially raised unique concerns about the potential excessive risk of postoperative infections. (ersjournals.com)
  • OBJECTIVE: The objective of this paper was to investigate the factors associated with successful epileptogenic zone (EZ) identification and postsurgical seizure freedom in pediatric patients with drug-resistant epilepsy who underwent first-time stereoelectroencephalography (SEEG). (bvsalud.org)
  • Patients with an older onset of epilepsy (OR 1.20/year, p = 0.04) or epilepsy etiology suspected to be due to a developmental lesion (OR 8.38, p = 0.02) were more likely to have proposed EZ identification. (bvsalud.org)
  • Patients with a preimplantation bilateral seizure-onset hypothesis (OR 0.29, p = 0.047) and those who underwent longer periods of monitoring (OR 0.86/day, p = 0.006) were somewhat less likely to have proposed EZ identification. (bvsalud.org)
  • This could explain the discrepancies between the above-cited human studies [9-12] concerning the relation between MAP and renal function as they included patients regardless of the existence or not of AKI at the time of inclusion. (igfprotein.com)
  • Patients with postoperative hypoxemia were classified as iNO and control groups. (biomedcentral.com)
  • In this study, we found that low-dose iNO improved oxygenation in patients with hypoxemia after AADA surgery and shortened the durations of mechanical ventilation and ICU stay. (biomedcentral.com)
  • Herein, we retrospectively analyzed the effects of low-dose iNO therapy in patients with postoperative hypoxemia after AADA and evaluated its efficacy and safety. (biomedcentral.com)
  • 3 Males and patients with later age of onset tend to have more severe disease and poorer prognosis. (lww.com)
  • However, it is important to acknowledge that our current understanding of prognosis is based on treatment approaches guided by clinical risk factors such as postoperative residual tumor volume and the presence of metastatic disease. (neurosurgery.directory)
  • Background: This study aimed to analyse the incidence and risk factors associated with postoperative cognitive dysfunction (POCD) after malignant tumour resection and cervical lymphatic dissection in older adults undergoing oral and maxillofacial surgery. (researchsquare.com)
  • The Ca 2+ -related activation of intracellular second messenger systems, the increase in reactive oxygen species formation, as well as hypoxia itself triggers the expression of a large number of pro-inflammatory genes following cerebral ischemia. (biomedcentral.com)
  • Hypoxia inducible factor-1α (HIF) is a transcriptional activator of genes, implicated in cerebral oedema formation in cerebral ischemic/reperfusion injury and controlled cortical impact models, but its role in BBI is not well defined. (naccs.org.uk)
  • The treatment of cerebral edema depends on the cause and includes monitoring of the person's airway and intracranial pressure, proper positioning, controlled hyperventilation, medications, fluid management, steroids. (wikipedia.org)
  • Younger age Higher severity of symptoms on the National Institutes of Health Stroke Scale Signs of current ischemia on clinical exam Decreased level of consciousness Hyper dense artery sign and larger affected area on CT imaging Higher blood glucose Cerebral edema has been traditional classified into two major sub-types: cytotoxic and vasogenic cerebral edema. (wikipedia.org)
  • We include updates from clinical trial findings that were not available at the time of these publications. (e-jnc.org)
  • In modern clinical practice, it is commonly used to assess the "intrinsic pathway" of hemostasis and is performed by adding calcium, phospholipid, and an activator such as kaolin to citrated blood, and the time to coagulation is measured. (e-jnc.org)
  • Postoperative cognitive dysfunction (POCD) is a postoperative central nervous system complication that often occurs hours to days after surgery. (researchsquare.com)
  • Additionally, the duration of surgery can be greatly increased as a result of such complication (De Castro et al. (springeropen.com)
  • and (3) normoglycemic, dexamethasone- and insulin-treated rats (group DI) received the same treatment as group D, plus an intravenous insulin infusion shortly before ischemia. (silverchair.com)
  • In contrast, all group D rats died of cerebral ischemia. (silverchair.com)
  • Cerebral revascularization is surgery that restores blood flow to the brain, decreasing the chance of stroke or other damage to brain tissue. (medscape.com)
  • Treatments that can reperfuse the ischemic brain regions as early as possible after stroke onset are critical for the prevention of brain-cell death. (en-journal.org)
  • Cerebral edema is excess accumulation of fluid (edema) in the intracellular or extracellular spaces of the brain. (wikipedia.org)
  • Extensive cerebral edema can also be treated surgically with a decompressive craniectomy. (wikipedia.org)
  • As cerebral edema is present with many common cerebral pathologies, the epidemiology of the disease is not easily defined. (wikipedia.org)
  • For example, malignant brain edema was present in roughly 31% of people with ischemic strokes within 30 days after onset. (wikipedia.org)
  • The following were reliable predictors for development of early cerebral edema in ischemic strokes. (wikipedia.org)
  • Some studies report that POCD still exists at three months after surgery, and can progress from chronic disease to long-term cognitive impairment [5].At the same time, POCD has the same pathological manifestations as dementia (Alzheimer Dementia, AD). (researchsquare.com)
  • In contrast, the presence of Burkholderia cepacia has been associated with a high risk of severe and often lethal postoperative infections, and consequently, with inferior survival rates. (ersjournals.com)
  • We examined the effects of the anesthetics isoflurane and pentobarbital, or hypothermia (30 degrees C), on the ability of rabbits to acquire an eyeblink conditioned response after 6.5 min of cerebral ischemia. (silverchair.com)
  • Animals in the hypothermia group were cooled to 30 degrees C before ischemia. (silverchair.com)
  • Prothrombin time. (lookformedical.com)
  • Common (or conventional) coagulation tests (CCT) include prothrombin time/international normalized ratio (PT/INR), activated partial thromboplastin time (aPTT), platelet count, D-dimer, and fibrinogen levels. (e-jnc.org)
  • Clotting time of PLASMA recalcified in the presence of excess TISSUE THROMBOPLASTIN. (lookformedical.com)
  • In later experiments we investigated the therapeutic time window of protection of nimesulide by delaying its first administration 0.5-4 h after the ischemic insult. (biomedcentral.com)
  • However, postoperative hypoxemia in AADA was different with ARDS in etiology and pathophysiology. (biomedcentral.com)
  • This prospective observational study aimed to measure pre- and postoperative plasma ascorbic acid levels and examine their association with delirium. (mdpi.com)
  • In a 15-year prospective cohort study of 132,250 Japanese subjects, Xu et al found that anemia and chronic kidney disease, alone and in combination, were associated with an increased risk of new-onset AF. (medscape.com)
  • If a person shows any of these symptoms, time is essential. (adam.com)
  • Further studies exploring associations between timing and tier of treatment initiation and longitudinal outcomes are needed. (bvsalud.org)
  • The advantages of ultrasound include (typically two to 15 MHz, but modern waves real-time visualization of the target structure, probes up to 22 MHz) being above the the distribution of the drug along and about frequency of waves that the human ear can the tissue, and the ability to control its distri- hear (20 to 20 000 Hz)7. (bvsalud.org)
  • Plasma glucose concentration immediately before ischemia was as follows: group P = 129 +/- 8 mg/dl (mean +/- SD), group D= 344 +/- 29 mg/dl, and group DI = 123 +/- 17 mg/dl. (silverchair.com)
  • The time required for the appearance of FIBRIN strands following the mixing of PLASMA with phospholipid platelet substitute (e.g., crude cephalins, soybean phosphatides). (lookformedical.com)
  • Clotting time of PLASMA mixed with a THROMBIN solution. (lookformedical.com)
  • Initial attempts to perform lung transplantation (LTx) were marred by technical limitations that often resulted in early postoperative death. (ersjournals.com)
  • Comparing initial audit (n=15) and re-audit (n=9), guidelines suggest targets to be achieved within a certain period of time. (naccs.org.uk)
  • The fifth-digit 1 is assigned regardless of the number of times a patient may be transferred during the initial episode of care. (theodora.com)
  • Similar lacking associations were observed in subgroup analysis based on ethnicity and age of onset. (limkinase-signal.com)
  • Increased pressures within the skull can cause a compensatory elevation of blood pressure to maintain cerebral blood flow, which, when associated with irregular breathing and a decreased heart rate, is called the Cushing reflex. (wikipedia.org)
  • The PT is a laboratory test developed to assess the function of the "extrinsic pathway" whereby calcium and tissue factor (TF) are added to citrated blood and the time to coagulation is measured. (e-jnc.org)
  • OBJECTIVE: We aimed to assess the treatment response of infantile-onset epileptic spasms (ES) in CDKL5 deficiency disorder (CDD) vs other etiologies. (bvsalud.org)
  • We compared the two cohorts for time to treatment and ES remission at 14 days and 3 months. (bvsalud.org)
  • However, this modality of therapy continues to be highly controversial because of uncertainty regarding the mechanism of action by which therapy is achieved and a lack of consensus protocols for certain applications because of the large number of parameters (e.g., frequency, energy, treatment timing, positioning) that can be selected. (surgicalneurologyint.com)
  • This study demonstrates that a brief episode of cerebral ischemia results in the impairment of associative learning. (silverchair.com)
  • RESULTS: We evaluated 59 individuals with CDD (79% female, median ES onset 6 months) and 232 individuals from the NISC database (46% female, median onset 7 months). (bvsalud.org)
  • In addition to the immunosuppressed status of the recipient, other factors that predispose to early bacterial pneumonias include the need for prolonged mechanical ventilatory support, blunted cough due to postoperative pain and weakness, disruption of lymphatics, and ischaemic injury to the bronchial mucosa with resultant impairment in mucociliary clearance. (ersjournals.com)
  • We previously found that iNO improved oxygenation after AADA and tended to decrease the time to extubation [ 11 ]. (biomedcentral.com)
  • Although not truly elective, autografting of the burn can usually be delayed for a short time if other problems need to be resolved. (renalandurologynews.com)
  • Three main reasons can be identified: (i) analyzing comorbidity depends on the type of available data (e.g., the type of detected diseases in the surveillance/study considered, study objective, target population), (ii) the burden of disease on a person's health depends on the severity or duration of the diseases or conditions, (iii) the presence of multiple morbidities must be aggregated in some way to offer a measure of comorbidity. (biomedcentral.com)