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Cell Line Tumor Cells, Cultured HeLa Cells Cell Line, Transformed Cell Line, Tumor Cells, Cultured Fibroblasts Cell Nucleus 3T3 Cells Chromosomes, Human, Pair 17 COS Cells HEK293 Cells

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Retroviridae Human T-lymphotropic virus 1 Mice, Transgenic Escherichia coli Cercopithecus aethiops Adenoviruses, Human Cricetinae Herpesvirus 8, Human Herpesvirus 4, Human Saccharomyces cerevisiae Mice, Mutant Strains Papillomaviridae Alpharetrovirus HIV-1 Mice, Inbred C57BL Avian leukosis virus

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Breast Neoplasms Ovarian Neoplasms Genetic Predisposition to Disease Cell Transformation, Neoplastic Cell Transformation, Viral Neoplasms Syndrome Neoplastic Syndromes, Hereditary Genetic Diseases, X-Linked Adenocarcinoma Lung Neoplasms Breast Neoplasms, Male Colorectal Neoplasms Chromosome Aberrations Genomic Instability Colorectal Neoplasms, Hereditary Nonpolyposis Chromosome Deletion Carcinoma Disease Models, Animal Retinitis Pigmentosa

Chemicals and Drugs70

BRCA1 Protein BRCA2 Protein Transcription Factors Neoplasm Proteins Rad51 Recombinase DNA-Binding Proteins DNA, Neoplasm Nuclear Proteins RNA, Messenger Tumor Suppressor Protein p53 Codon, Nonsense DNA Primers DNA Proto-Oncogene Proteins Oncogene Proteins, Viral Codon Trans-Activators Viral Proteins Carrier Proteins Membrane Proteins Gene Products, tax Repressor Proteins Tumor Suppressor Proteins Proto-Oncogene Proteins B-raf Proto-Oncogene Proteins c-myc DNA, Viral Adenovirus Early Proteins ras Proteins Proteins Ubiquitin-Protein Ligases DNA, Complementary Recombinant Fusion Proteins Epstein-Barr Virus Nuclear Antigens Cell Cycle Proteins Mutant Proteins Recombinant Proteins Protein-Serine-Threonine Kinases Proto-Oncogene Proteins p21(ras)Adenovirus E1A Proteins RNA, Viral Immediate-Early Proteins Retroviridae Proteins, Oncogenic Mutagens Genetic Markers DNA, Mitochondrial Oncogene Proteins MicroRNAs RNA Protein-Tyrosine Kinases RNA, Neoplasm Papillomavirus E7 Proteins MutS Homolog 2 Protein Bacterial Proteins Adaptor Proteins, Signal Transducing Eye Proteins Cytoskeletal Proteins Oligonucleotide Probes Antigens, Polyomavirus Transforming Oligodeoxyribonucleotides RNA, Small Interfering RNA Splice Sites Oncogene Protein p21(ras)Oncogene Protein p55(v-myc)Retroviridae Proteins Oncogene Proteins v-raf Ethylnitrosourea Receptor, Epidermal Growth Factor DNA Transposable Elements Homeodomain Proteins Tumor Markers, Biological

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Genetic Testing DNA Mutational Analysis Pedigree Polymerase Chain Reaction Transfection Sequence Analysis, DNA Amino Acid Substitution Mutagenesis, Site-Directed Cloning, Molecular Gene Expression Profiling Chromosome Mapping Oligonucleotide Array Sequence Analysis Heterozygote Detection Reverse Transcriptase Polymerase Chain Reaction Models, Genetic Nucleic Acid Hybridization Sequence Alignment Mutagenesis, Insertional Models, Molecular Immunohistochemistry Genetic Complementation Test Blotting, Western Blotting, Southern Restriction Mapping Models, Biological Case-Control Studies Blotting, Northern Prognosis Genetic Association Studies Transduction, Genetic Disease Models, Animal In Situ Hybridization, Fluorescence

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Phenomena and Processes111

Genes, BRCA1 Genes, BRCA2 Oncogenes Mutation Point Mutation Germ-Line Mutation Mutation, Missense Heterozygote Frameshift Mutation Base Sequence Genetic Predisposition to Disease Exons Polymorphism, Single-Stranded Conformational DNA Repair Genes, ras DNA Damage Genes, p53 Transcription, Genetic Phenotype Amino Acid Sequence Promoter Regions, Genetic Transfection Gene Expression Regulation Alleles Gene Expression Regulation, Viral Genotype Mutation Rate Amino Acid Substitution Homozygote Codon, Nonsense Sequence Deletion Cell Transformation, Viral Founder Effect Gene Expression Regulation, Neoplastic Proto-Oncogenes Gene Deletion Mutagenesis Transcriptional Activation Binding Sites Plasmids Codon Genes, Recessive Protein Structure, Tertiary Signal Transduction Protein Binding Genes, Tumor Suppressor Genes, Dominant Genes, myc Gene Expression Genes, Viral Genes Polymorphism, Genetic Gene Amplification Sequence Homology, Amino Acid Nucleic Acid Hybridization Loss of Heterozygosity Gene Frequency Virus Replication Mutagenesis, Insertional Cell Division Introns Recombination, Genetic Penetrance Genetic Linkage Terminal Repeat Sequences Consanguinity Repetitive Sequences, Nucleic Acid Apoptosis Polymorphism, Restriction Fragment Length Cell Cycle Microsatellite Repeats Suppression, Genetic Phosphorylation Genetic Variation Chromosomes, Human, Pair 17 Genetic Vectors Exome RNA Splicing Genes, APC Gene Dosage Polymorphism, Single Nucleotide Gene Silencing Genetic Markers DNA Methylation Genes, Reporter Down-Regulation Kinetics Chromosome Aberrations Time Factors Conserved Sequence Genomic Instability Alternative Splicing Protein Biosynthesis Sequence Homology, Nucleic Acid Cell Proliferation Structure-Activity Relationship Transduction, Genetic Host-Pathogen Interactions Genes, Lethal Virus Integration DNA Mismatch Repair Chromosome Deletion Enhancer Elements, Genetic RNA Splice Sites Open Reading Frames DNA Replication Cell Differentiation Gene Rearrangement DNA Transposable Elements RNA Interference Genes, Neoplasm

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BRCA1 Protein Genes, BRCA1 BRCA2 Protein Genes, BRCA2 Oncogenes Mutation Point Mutation Germ-Line Mutation Mutation, Missense Breast Neoplasms Heterozygote Ovarian Neoplasms Genetic Testing Frameshift Mutation DNA Mutational Analysis Base Sequence Transcription Factors Genetic Predisposition to Disease Neoplasm Proteins Pedigree Molecular Sequence Data Rad51 Recombinase Exons Polymorphism, Single-Stranded Conformational Polymerase Chain Reaction DNA Repair Cell Transformation, Neoplastic Cell Line Genes, ras DNA Damage Genes, p53 DNA-Binding Proteins Transcription, Genetic Phenotype Tumor Cells, Cultured Amino Acid Sequence Promoter Regions, Genetic DNA, Neoplasm Transfection Gene Expression Regulation Alleles Gene Expression Regulation, Viral Genotype Nuclear Proteins Mutation Rate RNA, Messenger Sequence Analysis, DNA Amino Acid Substitution Tumor Suppressor Protein p53 Homozygote Codon, Nonsense DNA Primers Sequence Deletion DNA Cell Transformation, Viral Founder Effect Gene Expression Regulation, Neoplastic Jews Proto-Oncogenes Proto-Oncogene Proteins Gene Deletion Mutagenesis Oncogene Proteins, Viral Transcriptional Activation Mutagenesis, Site-Directed Cloning, Molecular Gene Expression Profiling HeLa Cells Binding Sites Plasmids Codon Cell Line, Transformed Trans-Activators Chromosome Mapping Genes, Recessive Protein Structure, Tertiary Signal Transduction Protein Binding Cell Line, Tumor Oligonucleotide Array Sequence Analysis Cells, Cultured Genes, Tumor Suppressor Genes, Dominant Genes, myc Gene Expression Family Health Heterozygote Detection Viral Proteins Genes, Viral Carrier Proteins Reverse Transcriptase Polymerase Chain Reaction Fibroblasts Membrane Proteins Genes Gene Products, tax Repressor Proteins Models, Genetic Tumor Suppressor Proteins Retroviridae Neoplasms

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