• We have now investigated whether a sciatic nerve crush injury alters the behavioral response in rats to tactile stimuli and whether this is associated with a change in the pattern of c-Fos expression in the dorsal horn and the parabrachial area of the brainstem. (nih.gov)
  • Nigrostriatal lesions alter oral dyskinesia and c-Fos expression induced by the serotonin agonist 1-(m-chlorophenyl)piperazine in adult rats. (mendeley.com)
  • In intact rats, Fos expression was increased by m-CPP (1 mg/kg, i.p.) in the striatum and the subthalamic nucleus. (mendeley.com)
  • We show that light alters the immunoreactive levels of a transcriptional regulatory protein, Fos, in the suprachiasmatic nuclei of albino rats. (umassmed.edu)
  • Specifically, the effects of unilateral lesions of nigrostriatal DA neurons on oral dyskinesia and Fos protein expression induced by the non-selective 5-HT(2C) agonist 1-(m-chlorophenyl)piperazine (m-CPP) were examined. (mendeley.com)
  • Dura-sensitive neurons were recorded in the Vc and the production of c-Fos-like immunoreactivity was quantified. (elsevier.com)
  • Results In chronic morphine-treated animals, naloxone methiodide microinjections produced a significant increase both in ongoing and facial heat-evoked activity and an increase in Fos-positive neurons in the Vc and in the nucleus reticularis dorsalis, a brainstem region involved in diffuse noxious inhibitory controls. (elsevier.com)
  • Double labeling for c-Fos and CTb revealed a significant recruitment of LH-projecting neurons in nucleus accumbens shell (AcbSh) during reinstatement. (edu.au)
  • However, some recent studies challenge this view as they indicate that c-fos has tumor suppressor activity. (por.hu)
  • The above findings suggest that loss of c-fos expression has tumor suppressor activity in gastric cancer and we suspect that this suppressor activity might be related to the pro-apoptotic function of c-fos. (por.hu)
  • The FBJ-MSV v-fos gene encodes a p55-kDa protein and the FBR-MSV v-fos gene encodes a p75-kDa fusion protein. (definitions.net)
  • p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence. (uniprot.org)
  • p>Describes annotations that are concluded from looking at variations or changes in a gene product such as mutations or abnormal levels and includes techniques such as knockouts, overexpression, anti-sense experiments and use of specific protein inhibitors. (uniprot.org)
  • Wog, but not N-Wog, significantly inhibits LPS- or LTA-induced NO production through suppressing iNOS gene expression at both protein and mRNA without affecting NO donor sodium nitroprusside-induced NO production, NOS enzyme activity, and cells viability. (elsevier.com)
  • Jun dimerization protein 2 (JUNDM2) is a protein that in humans is encoded by the JDP2 gene. (wikipedia.org)
  • Stimulation of the VTA resulted in increased levels of c-Fos immunostaining in several target regions of the mesolimbic dopaminergic system (such as the frontal cortex, olfactory tubercle, islands of Calleja and amygdala), with the notable exception of the nucleus accumbens. (edu.au)
  • These proteins have been found in the Finkel-Biskis-Jinkins (FBJ-MSV) and Finkel-Biskis-Reilly (FBR-MSV) murine sarcoma viruses which induce osteogenic sarcomas in mice. (definitions.net)
  • By contrast, JDP2-knockout mice exhibit in downregulation of p53 and p21 proteins. (wikipedia.org)
  • Black dots represent c-Fos immunopositive nuclei. (nih.gov)
  • In contrast, the lateral mammillary nuclei lesions were found to decrease retrosplenial c-Fos levels. (bireme.br)
  • a) The diagrams indicate the location of brain regions selected for c-Fos quantification. (nih.gov)
  • The effect of olcegepant, L-nitro-arginine methyl ester (L-NAME) and neurokinin (NK)-1 receptor antagonist L-733060 were analysed on Fos activation. (forskningsdatabasen.dk)
  • While most Fos proteins exist as a single isoform, the FosB protein exists as two isoforms: full-length FosB and a shorter form, FosB2 (Delta FosB), that lacks the carboxy-termil 101 amino acids (1-3). (acris-antibodies.com)
  • Phosphorylation of FRA1 at Ser252 and Ser265 by Erk1/2 increases protein stability and leads to overexpression of FRA1 in cancer cells (6). (acris-antibodies.com)
  • CCAAT/enhancer-binding protein gamma (C/EBPγ), HDAC3 and HDAC6 have also been demonstrated to associate with JDP2. (wikipedia.org)
  • We then used the retrograde neuronal tracer cholera toxin b subunit (CTb) combined with detection of the c-Fos protein to identify activated afferents to LH during context-induced reinstatement of beer seeking. (edu.au)
  • It contains putative SUMO modification of lysine (Lys) residue at position 65, and recruits interferon regulatory factor 2 binding protein 1 (IRF2BP1), which acts as an E3 ligase. (wikipedia.org)
  • Other proteins such as interferon regulatory factor-2-binding protein-1 (IRF2BP1). (wikipedia.org)
  • After 27 days, we evaluated the central nervous system (CNS) pathways involved in the effect induced by experimental drugs through immunofluorescence protocol to Fos protein. (nih.gov)