• Nuclear Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (uams.edu)
  • Below are the most recent publications written about "Nuclear Proteins" by people in Profiles over the past ten years. (uams.edu)
  • Proto-Oncogene Proteins c-mdm2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (umassmed.edu)
  • This graph shows the total number of publications written about "Proto-Oncogene Proteins c-mdm2" by people in this website by year, and whether "Proto-Oncogene Proteins c-mdm2" was a major or minor topic of these publications. (umassmed.edu)
  • Below are the most recent publications written about "Proto-Oncogene Proteins c-mdm2" by people in Profiles. (umassmed.edu)
  • Many of these proteins are similar in structure to known NUCLEAR RECEPTORS but appear to lack a functional ligand-binding domain, while in other cases the specific ligands have yet to be identified. (nih.gov)
  • Do not confuse with NUCLEOPROTEINS which are proteins conjugated with nucleic acids, that are not necessarily present in the nucleus. (uams.edu)
  • Rel frequently combines with other related proteins (NF-KAPPA B, I-kappa B, relA) to form heterodimers that regulate transcription. (bvsalud.org)
  • MeSH D12.776.503.280.249.500 - mannose-binding lectin MeSH D12.776.503.280.249.600 - pulmonary surfactant-associated protein a MeSH D12.776.503.280.249.625 - pulmonary surfactant-associated protein d MeSH D12.776.503.499.968.900 - wheat germ agglutinin-horseradish peroxidase conjugate See List of MeSH codes (D12.776.543). (wikipedia.org)
  • Immunoglobulin J Recombination Signal Sequence-Binding Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (harvard.edu)
  • It contains an N-terminal RING FINGER DOMAIN and is a PROTEIN PHOSPHATASE 1 regulatory subunit. (jefferson.edu)
  • These complexes function in DNA repair pathways, primarily DNA MISMATCH REPAIR , where MutL/MLH1 and the MUTS DNA MISMATCH-BINDING PROTEIN are targeted to damaged DNA . (nih.gov)
  • Members of this family of proteins are often found associated with histone-modifying enzymes and protein complexes that regulate gene expression. (bvsalud.org)
  • The protein plays a role in regulating DNA topology and activation of RIBOSOMAL RNA transcription. (childrensmercy.org)
  • Below are the most recent publications written about "Leucine-Responsive Regulatory Protein" by people in Profiles. (rush.edu)
  • A family of endogenous regulatory proteins that associate with RETINOBLASTOMA PROTEIN via a specific high-affinity binding domain. (bvsalud.org)
  • In normal cells the BRCA1 protein is localized in the nucleus, whereas in the majority of breast cancer cell lines and in malignant pleural effusions from breast cancer patients, it is localized mainly in the cytoplasm. (jefferson.edu)
  • A broad category of receptor-like proteins that may play a role in transcriptional-regulation in the CELL NUCLEUS . (nih.gov)
  • Proteins found in the nucleus of a cell. (uams.edu)
  • we conditionally induced self-renewal efficiently within neural progenitors solely by introducing v-myc tightly regulated by a tetracycline (Tet)-on gene expression system. (nih.gov)
  • A LEUCINE and DNA-binding protein that is found primarily in BACTERIA and ARCHAEA. (rush.edu)
  • A highly abundant DNA binding protein whose expression is strongly correlated with the growth phase of bacteria. (childrensmercy.org)
  • A ubiquitously expressed sequence-specific transcriptional repressor that is normally the target of signaling by NOTCH PROTEINS. (harvard.edu)
  • This graph shows the total number of publications written about "Immunoglobulin J Recombination Signal Sequence-Binding Protein" by people in Harvard Catalyst Profiles by year, and whether "Immunoglobulin J Recombination Signal Sequence-Binding Protein" was a major or minor topic of these publication. (harvard.edu)
  • A DNA-binding protein that consists of 5 polypeptides and plays an essential role in DNA REPLICATION in eukaryotes. (childrensmercy.org)
  • Proteins containing AT-HOOK MOTIFS that are rich in arginine and glycine residues. (uchicago.edu)
  • To describe the clinical features, muscle pathological characteristics, and molecular studies of a patient with a mutation in the gene encoding the accessory subunit (p55) of polymerase gamma (POLG2) and a mutation in the OPA1 gene. (nih.gov)
  • We analysed the epigenomic consequences of rearrangements between the super-enhancers of the immunoglobulin heavy locus () and proto-oncogene that are common in B cell malignancies. (babraham.ac.uk)
  • MeSH D12.776.503.280.249.500 - mannose-binding lectin MeSH D12.776.503.280.249.600 - pulmonary surfactant-associated protein a MeSH D12.776.503.280.249.625 - pulmonary surfactant-associated protein d MeSH D12.776.503.499.968.900 - wheat germ agglutinin-horseradish peroxidase conjugate See List of MeSH codes (D12.776.543). (wikipedia.org)
  • Inner nuclear protein Matrin-3 coordinates cell differentiation by stabilizing chromatin architecture. (umassmed.edu)
  • A set of nuclear proteins in SACCHAROMYCES CEREVISIAE that are required for the transcriptional repression of the silent mating type loci. (uams.edu)
  • A nuclear and cytoplasmic protein that associates with KINETOCHORES and contains a C-terminal TUDOR DOMAIN. (jefferson.edu)
  • A nuclear protein and tumor suppressor that contains a C-terminal PHD ZINC FINGER. (bvsalud.org)
  • This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. (nih.gov)
  • Probe Set ID Ref Seq Protein ID Signal Strength Name Gene Symbol Species Function Swiss-Prot ID Amino Acid Sequence 1367452_at NP_598278 16.52 small ubiquitin-related modifier 2 precursor Sumo2 Rattus norvegicus " Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. (nih.gov)
  • Regulates E3 ubiquitin-protein ligase activity of RNF19A (By similarity). (nih.gov)
  • A DNA-binding protein and AAA ATPase that consists of 5 polypeptides and plays an essential role in DNA REPLICATION in eukaryotes. (ucdenver.edu)
  • It may also function in M PHASE CELL CYCLE CHECKPOINTS and as an enhancer of TUMOR SUPPRESSOR PROTEIN P53-mediated transcriptional activation. (jefferson.edu)
  • Point mutations in the cellular ras gene (c-ras) can also result in a mutant p21 protein that can transform mammalian cells. (uams.edu)
  • What does this gene/protein do? (cancerindex.org)
  • What pathways are this gene/protein implicaed in? (cancerindex.org)
  • Inhibition of apoptosis by pentachlorophenol in v-myc-transfected rat liver epithelial cells: relation to down-regulation of gap junctional intercellular communication. (nih.gov)
  • To test the hypothesis that both inhibition of GJIC and apoptosis contribute to tumor promotion, we investigated the effect of PCP on both GJIC and serum deprivation-induced apoptosis in v-myc-transfected rat liver epithelial cells. (nih.gov)
  • PknB-IN-2 (Compound 10) is a Mycobacterium tuberculosis protein kinase B ( PknB ) inhibitor with an IC 50 of 12.1 μM. (medchemexpress.com)
  • Cdc7-IN-5 (compound I- B ) is a potent Cdc7 kinase inhibitor extracted from patent WO2019165473A1, compound I- B . Cdc7 is a serine-threonine protein kinase enzyme which is essential for the initiation of DNA replication in the cell cycle. (medchemexpress.com)
  • B -Raf IN 5 (compound 3 b ) is a potent inhibitor of protein kinase B-Raf with an IC 50 of 2.0 nM. (medchemexpress.com)
  • OTS964 hydrochloride is an orally active, high affinity and selective TOPK (T-lymphokine-activated killer cell-originated protein kinase ) inhibitor with an IC 50 of 28 nM. (medchemexpress.com)
  • ROCK-IN-5 (compound I- B -37) is a potent inhibitor of ROCK , ERK , GSK , and AGC protein kinases . (medchemexpress.com)
  • Se expresa en diferentes isoformas en diversos tejidos e interacciona con la PROTEÍNA SUPRESORA DE TUMOR P53 para regular negativamente el crecimiento celular. (bvsalud.org)
  • It is expressed in different isoforms in various tissues and interacts with TUMOR SUPPRESSOR PROTEIN P53 to negatively regulate cell growth. (bvsalud.org)
  • It interacts directly with FANCG PROTEIN and helps stabilize a complex with FANCA PROTEIN and FANCC PROTEIN . (nih.gov)
  • 13. Spectral karyotyping and fluorescence in situ hybridization detect novel chromosomal aberrations, a recurring involvement of chromosome 21 and amplification of the MYC oncogene in acute myeloid leukaemia M2. (nih.gov)
  • Protein kinase affinity probe 1 is a novel protein kinase affinity probe for the functional identification of protein kinases (PKs) . (medchemexpress.com)
  • Protein kinase affinity probe 1 is a modified Purvalanol B (HY-18299) probe with 50% beads loading (Compound S3). (medchemexpress.com)
  • MS5033 is a potent PROTAC-based AKT ( protein kinase B) degrader, with a DC 50 of 430 nM in PC3 cells. (medchemexpress.com)
  • The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. (nih.gov)
  • Chromosomal Proteins, Non-Histone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (umassmed.edu)
  • Silent Information Regulator Proteins, Saccharomyces cerevisiae" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (uams.edu)
  • Oncogene Protein p21(ras)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (uams.edu)
  • Replication Protein C" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (ucdenver.edu)
  • Chromosomal translocations are important drivers of hematological malignancies whereby proto-oncogenes are activated by juxtaposition with super-enhancers, often called enhancer hijacking. (babraham.ac.uk)
  • CCAAT enhancer binding protein delt. (gsea-msigdb.org)
  • Loss of LXR-beta function is associated with an increase in the expression of UNCOUPLING PROTEIN 1 as well as OBESITY. (bvsalud.org)
  • 9. Glucocorticoids induce G1 arrest of lymphoblastic cells through retinoblastoma protein Rb1 dephosphorylation in childhood acute lymphoblastic leukemia in vivo. (nih.gov)
  • adaptor related protein complex 2 s. (gsea-msigdb.org)
  • Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (nih.gov)
  • As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. (cancerindex.org)
  • Epigenomic translocation of H3K4me3 broad domains over oncogenes following hijacking of super-enhancers. (babraham.ac.uk)
  • This graph shows the total number of publications written about "Chromosomal Proteins, Non-Histone" by people in this website by year, and whether "Chromosomal Proteins, Non-Histone" was a major or minor topic of these publications. (umassmed.edu)
  • Below are the most recent publications written about "Chromosomal Proteins, Non-Histone" by people in Profiles. (umassmed.edu)
  • Below are the most recent publications written about "Silent Information Regulator Proteins, Saccharomyces cerevisiae" by people in Profiles over the past ten years. (uams.edu)
  • Below are the most recent publications written about "Oncogene Protein p21(ras)" by people in Profiles over the past ten years. (uams.edu)
  • Below are the most recent publications written about "Replication Protein C" by people in Profiles. (ucdenver.edu)
  • Oncogene protein p21(ras) has been directly implicated in human neoplasms, perhaps accounting for as much as 15-20% of all human tumors. (uams.edu)
  • The cytosine deaminase APOBEC proteins have been implicated in the mutational signatures of more than 70% of human cancers. (bvsalud.org)