In molecular genetics, a regulon is a group of genes that are regulated as a unit, generally controlled by the same regulatory gene that expresses a protein acting as a repressor or activator. (wikipedia.org)
the genes contained within a regulon are usually organized into more than one operon at disparate locations on the chromosome. (wikipedia.org)
The Ada regulon in E. coli is a well-characterized example of a group of genes involved in the adaptive response form of DNA repair. (wikipedia.org)
Member of the two-component regulatory system EnvZ/OmpR involved in osmoregulation (particularly of genes ompF and ompC) as well as other genes. (string-db.org)
Phosphate2
an often-studied example is the phosphate regulon in E. coli, which couples phosphate homeostasis to pathogenicity through a two-component system. (wikipedia.org)
at low osmolarity OmpR activates ompF transcription, while at high osmolarity it represses ompF and activates ompC transcription. (string-db.org)
Protein1
An example of the effects of different regulatory environments for homologous proteins is the DNA-binding protein OmpR, which is involved in response to osmotic stress in E. coli but is involved in response to acidic environments in the close relative Salmonella Typhimurium. (wikipedia.org)
A modulon is a set of regulons or operons that are collectively regulated in response to changes in overall conditions or stresses, but may be under the control of different or overlapping regulatory molecules. (wikipedia.org)
Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR. (string-db.org)
Response2
Commonly studied regulons in bacteria are those involved in response to stress such as heat shock. (wikipedia.org)
The heat shock response in E. coli is regulated by the sigma factor σ32 (RpoH), whose regulon has been characterized as containing at least 89 open reading frames. (wikipedia.org)
Under these conditions, the anaeroresponsive ArcB/ArcA system, the osmoresponsive EnvZ/OmpR system and the response regulator UvrY showed the most drastic changes. (nih.gov)
Using the OmpR protein, we identify residues in the flexible linker and the C-terminal β-hairpin that enable associations of this archetypical response regulator with thioredoxin, but are dispensable for interactions of this transcription factor to its cognate sensor kinase EnvZ, DNA or RNA polymerase. (nature.com)
In this paper, we reported the characterization of a transcriptional regulator in Azorhizobium caulinodans ORS571, ActR, with an N-terminal receiver domain and one C-terminal OmpR/PhoB-type DNA binding domain. (sciencegate.app)
Operons1
A modulon is a set of regulons or operons that are collectively regulated in response to changes in overall conditions or stresses, but may be under the control of different or overlapping regulatory molecules. (wikipedia.org)
Bacteria2
Commonly studied regulons in bacteria are those involved in response to stress such as heat shock. (wikipedia.org)
In E. coli [313] and in some other bacteria, the putative regulon CRP-Sxy has been identified through microarray analysis [161, 314] . (unam.mx)
Gene2
In molecular genetics, a regulon is a group of genes that are regulated as a unit, generally controlled by the same regulatory gene that expresses a protein acting as a repressor or activator. (wikipedia.org)
An 13375-overexpressing mutant G1-OE13375, which constitutively express C-terminally Myc-tagged ompR-like gene in the 13375-deletion mutant G1Δ13375, was used in this study. (nih.gov)
Proteins1
An example of the effects of different regulatory environments for homologous proteins is the DNA-binding protein OmpR, which is involved in response to osmotic stress in E. coli but is involved in response to acidic environments in the close relative Salmonella Typhimurium. (wikipedia.org)
Coli2
The heat shock response in E. coli is regulated by the sigma factor σ32 (RpoH), whose regulon has been characterized as containing at least 89 open reading frames. (wikipedia.org)
an often-studied example is the phosphate regulon in E. coli, which couples phosphate homeostasis to pathogenicity through a two-component system. (wikipedia.org)
Systems1
Cellular functions such as flagellar synthesis and expression of the RpoS regulon were affected by multiple two-component systems. (nih.gov)