Olfactory and limbic. Medical search. Frequent questions

The mammalian telencephalon, which comprises the cerebral cortex, olfactory bulb, hippocampus, basal ganglia (striatum and globus pallidum), and amygdala, is a highly complex and evolutionarily advanced brain structure. (intechopen.com)
Inhalation through the nose stimulates neurons in areas of the brain (olfactory cortex, amygdala, and hippocampus) tied to emotions and memory. (neurosciencenews.com)
When you breathe in, we discovered you are stimulating neurons in the olfactory cortex, amygdala and hippocampus, all across the limbic system. (neurosciencenews.com)
All the rest interact with the thalamus, the brain's sensory relay, but smell attaches to the limbic system: the hypothalamus, the hippocampus and the amygdala, systems that elicit fear, instinct, vigor. (michigandaily.com)
Another key part of the limbic system is called the hippocampus. (youngliving.com)
Mouse EphA5 is expressed exclusively in brain with the highest levels in the hippocampus and limbic system (5). (rndsystems.com)
I won't bore you by getting into the science of smells, and start mentioning things such as olfactory bulbs, limbic systems, and the hippocampus. (dealerrefresh.com)
Your olfactory bulbs, which record the sense of smell, lie almost on top of your hippocampus. (dummies.com)

Odor-evoked responses are conducted from olfactory receptor neurons at the nasal mucosa toward the olfactory bulb. (jneurosci.org)
As olfactory bulb (OB) circuitry plays a critical role in odour learning, we studied the plausible changes in the OB of ELS mice. (nature.com)
Mammalian olfactory bulb (OB) is a specialised pre-cortical area of the brain that processes smell and can be modulated by the affective states. (nature.com)
The small, unmyelinated axons of the olfactory receptor cells form the fine fibers of the first cranial nerve and travel centrally toward the ipsilateral olfactory bulb to make contact with the second-order neurons. (medscape.com)
The olfactory bulb lies inferior to the basal frontal lobe. (medscape.com)
The olfactory bulb is a highly organized structure composed of several distinct layers and synaptic specializations. (medscape.com)
Mitral cells are second-order neurons contacted by the olfactory nerve fibers at the glomerular layer of the bulb. (medscape.com)
The findings are published in Neuron in an article titled, " Reinstating olfactory bulb-derived limbic gamma oscillations alleviates depression-like behavioral deficits in rodents . (genengnews.com)
Here, we show that transient functional suppression of olfactory bulb neurons or their piriform cortex efferents decreased gamma oscillation power in limbic areas and induced depression-like behaviors in rodents. (genengnews.com)
These regions include the olfactory bulb adjacent to the nasal cavity, which is thought to be a source and "conductor" of brain-wide gamma oscillations. (genengnews.com)
These tests revealed that chronic suppression of olfactory bulb signals, including gamma, not only induced depressive behaviors during the intervention, but for days afterward. (genengnews.com)
The brain's olfactory bulb is part of the limbic system, which includes structures that are vital to our mood, behavior and memory. (bethesdaworkshops.org)
This tells the neurons there to generate a message for the olfactory bulb, which processes the signal and sends information about the smell to the limbic system-the center of emotion and memory. (youngliving.com)
It sends a signal to the brain to decode, which first arrives at the olfactory bulb. (niche-beauty.com)
In the nostrils there is the olfactory mucosa which is responsible for receiving the "odorific message" (the smell or aroma), which will be transported by the olfactory nerve fibers to the olfactory bulb. (botanical-online.com)
Conveniently the limbic brain is co-located with our olfactory bulb, which explains why our sense of smell both heightens our emotional experience and connects us to our memories so powerfully. (goodcleanlove.com)

The olfactory system, which is responsible for smell, is the sense most closed connected to the limbic system. (plt.org)
We know that smell receptors are connected to the limbic system, the same place that processes emotions and memory. (neural.it)
Essential Oils have an effect on the brain via the Olfactory system, which is just above the nose and connected to the Limbic system. (57aromas.com)

Activation of circuits regulating these innate behaviors begins in the periphery with sensory stimulation (primarily via the olfactory system in rodents), and is then processed in the brain by a set of delineated structures that primarily includes the amygdala and hypothalamus. (frontiersin.org)
When you inhale essential oils, their chemical components stimulate olfactory receptor neurons, which then transmit signals to your limbic system and hypothalamus. (naturalnews.com)
The limbic system is the part of your brain involved in emotional and behavioral responses , while the hypothalamus is the part of your brain that produces hormones responsible for controlling your body temperature, heart rate, hunger, mood, sleep and thirst. (naturalnews.com)
The limbic system is located within the hypothalamus. (myalchemilla.com)
In aromatherapy, it is believed that when certain scent molecules are encountered, the limbic system processes the information and determines the actions that the hypothalamus will take. (myalchemilla.com)
The hypothalamus is another helpful figure in our limbic system. (youngliving.com)

This neural network, dubbed the "limbic system" is centered around the amygdala, a small almond shaped structure located deep within the temporal lobe. (frontiersin.org)
Found in the brain's complex limbic system, the amygdala is an almond-shaped mass that deals with emotional responses, especially negative ones like fear and disgust. (youngliving.com)

We first experimentally characterized the neuronal pathway by delivering different sets of electrical stimuli from the lateral olfactory tract (LOT) and by recording the corresponding responses in the lateral entorhinal cortex (l-ERC). (unige.it)
In primary olfactory (piriform) cortex, spatially and temporally dissociable responses were identified along a rostrocaudal axis. (jneurosci.org)
Second-order projections transmit via the lateral olfactory tract and terminate in adjacent structures collectively labeled "primary olfactory cortex. (jneurosci.org)
Piriform cortex is the major recipient of bulbar afferents, but additional targets comprise olfactory tubercle, anterior olfactory nucleus, periamygdaloid cortex, and entorhinal area. (jneurosci.org)
Neuroimaging studies have begun to identify important olfactory structures, but one notable feature is the inconsistent activation of piriform cortex ( Zald and Pardo, 2000 ). (jneurosci.org)
Once the signals reach your olfactory cortex -- the part of your brain concerned with the sense of smell -- they trigger the release of specific brain chemicals, or neurotransmitters, like serotonin. (naturalnews.com)
Moreover, there were significant negative correlations between right UF FA and olfactory cortex FC to both the gyrus rectus and OFC within the nIHH and HC groups. (researchsquare.com)
The results may indicate that a specific structural-functional asymmetry exists in the olfactory cortex pathways in KS patients. (researchsquare.com)
An increasing number of neuroimaging articles on the olfactory system have significantly contributed to the localization of the olfactory cortex. (researchsquare.com)
However, localization of the olfactory cortex has also presented significant challenges to the scientific community. (researchsquare.com)
Yet you also have a large cerebral cortex sitting right on top of this limbic system that tempers and controls those emotions. (dummies.com)

Olfactory receptors. (medscape.com)
The current research team designed a reversible method to avert damage, starting with a single, engineered strand of DNA encapsulated in a harmless virus, which when injected into neurons in the olfactory bulbs of rodents caused the cells to build certain protein receptors on their surfaces. (genengnews.com)
They are received via olfactory receptors, which are highly concentrated in the limbic system, the primitive part of the brain and seat of emotion. (morter.com)
The nose has around 450 olfactory receptors responsible for detecting scent. (niche-beauty.com)
It is a specialized pseudostratified neuroepithelium containing the primary olfactory receptors. (medscape.com)
To stimulate the olfactory receptors, airborne molecules must pass through the nasal cavity with relatively turbulent air currents and contact the receptors. (medscape.com)

However, these effects are tied to inhaling through the nose, not the mouth, and influence the brain's limbic system, which includes regions for emotions and memory. (neurosciencenews.com)

The continuous turnover and new supply of these neurons are unique to the olfactory system. (medscape.com)
In addition to the olfactory neurons, the epithelium is composed of supporting cells, Bowman glands and ducts unique to the olfactory epithelium, and basal cells that allow for the regeneration of the epithelium, including the olfactory sensory neurons. (medscape.com)

Within the nasal cavity , the turbinates or nasal conchae serve to direct the inspired air toward the olfactory epithelium in the upper posterior region. (medscape.com)
The nasal cavity contains olfactory nerves, which are extremely sensitive to airborne molecules that get stuck to the mucous membrane within the nose. (myalchemilla.com)
The olfactory neuroepithelium is located at the upper area of each nasal chamber adjacent to the cribriform plate, superior nasal septum, and superior-lateral nasal wall. (medscape.com)

As the scientific community accepted emotions such as fear, anxiety, reward, and attraction as a result of neural wiring in humans, other species including rodents were gradually accepted as possessing similar circuits and, therefore, similar emotions (see Figure 1 for comparison of human and rodent limbic system structures). (frontiersin.org)
This information is passed on to the limbic system, structures in the brain scientists believe contribute to controlling mood and behavior. (niche-beauty.com)
The limbic system is composed of a set of structures whose function is related to emotional responses, learning and memory . (botanical-online.com)

I will break it down this way: odor molecules make their way high into your nose, stimulating olfactory sensory neurons and sending electrical impulses directly to your limbic system - that's the distinction between smell and all other senses. (michigandaily.com)

The olfactory epithelium consists of 3 cell types: basal, supporting, and olfactory receptor cells. (medscape.com)
As previously mentioned, the trigeminal nerve (cranial nerve V) sends fibers to the olfactory epithelium to detect caustic chemicals, such as ammonia. (medscape.com)
Research shows that the active components of essential oils can stimulate parts of the brain through the olfactory epithelium. (naturalnews.com)
The most important cells in the olfactory epithelium are the olfactory receptor neurons, which help transmit olfactory information to the brain. (naturalnews.com)

The aromas inhaled by the nose reach the limbic system of the brain through the olfactory nerves. (essentialoil.net)
Odorants can also be perceived by entering the nose posteriorly through the nasopharynx to reach the olfactory receptor via retronasal olfaction. (medscape.com)

The Smell Identification Test was performed to evaluate olfactory function ( 14 ). (researchsquare.com)
Simply stated, when a smell arrives at the limbic system, the brain releases unique neurochemicals, triggering a variety of reactions. (youngliving.com)
When we smell a fragrance, our limbic system is activated, and this ignites our olfactory glands, which can evoke an emotion, and even draw us into a memory. (naplesgarden.org)
Abουt aromatherapy, whenever wе smell something, olfactory receptor transmits a note towards thе edge system.Thіѕ instinct limbic system involved wіth feelings аnd feelings. (natural-living-for-women.com)
Trust your sense of smell to excite you and indulge your olfactory in whatever scents turn you on. (goodcleanlove.com)
The sense of smell is mediated through stimulation of the olfactory receptor cells by volatile chemicals. (medscape.com)

The limbic system predominantly controls appropriate responses to stimuli with social, emotional, or motivational salience, which includes innate behaviors such as mating, aggression, and defense. (frontiersin.org)
My research focuses on the often neglected role of expectation and anticipatory attention in prioritization of emotional stimuli both in the visual and olfactory modalities. (psychologicalscience.org)

Head anatomy with olfactory nerve. (medscape.com)
The cribriform plate of the ethmoid bone, separated at the midline by the crista galli, contains multiple small foramina through which the olfactory nerve fibers, or fila olfactoria, traverse. (medscape.com)
The glomerular layer is the most superficial layer, consisting of mitral cell dendritic arborizations (glomeruli), olfactory nerve fibers, and periglomerular cells. (medscape.com)
Each mitral cell is contacted by at least 1000 olfactory nerve fibers. (medscape.com)
Brain infection is thought to occur by means of direct neuronal transmission of the virus from a peripheral site to the brain via the trigeminal or olfactory nerve and indirect immune-mediated processes inducing neuroinflammation. (medscape.com)

What we share, however, is the fact that our olfactory nerves have a direct line of communication to our limbic systems, the part of the brain that deals with emotions and memories. (countrylife.co.uk)

When translating from rodent models to humans, it is important to understand that the sensory inputs of rodents are primarily olfactory, auditory, and somatosensory, with minimal visual inputs. (frontiersin.org)
Early developmental events involving the olfactory and limbic system start and conclude possibly slightly early in primates than rodents, and we find a comparable early conclusion of primate hippocampal neurogenesis (as assessed by the relative number of Ki67 cells) suggesting a plateau to low levels at approximately 2 years of age in humans. (figshare.com)

They also show that brain regions mediating emotional processing are differentially activated by odor valence, providing evidence for a close anatomical coupling between olfactory and emotional processes. (jneurosci.org)
We also discuss how understanding developmental processes of innate circuit formation may inform behavioral alterations observed in neurodevelopmental disorders, such as autism spectrum disorders, which are characterized by limbic system dysfunction. (frontiersin.org)
Activation occurs when odiferous molecules come in contact with specialized processes known as the olfactory vesicles. (medscape.com)

The endless jokes about our olfactory bulbs span across the grade levels. (edutopia.org)

Basal cells are stem cells that give rise to the olfactory receptor cells (seen in the image below). (medscape.com)

This area (only a few centimeters wide) contains more than 100 million olfactory receptor cells. (medscape.com)
The receptor cells are actually bipolar neurons, each possessing a thin dendritic rod that contains specialized cilia extending from the olfactory vesicle and a long central process that forms the fila olfactoria. (medscape.com)

We sought to define the neural substrates of human olfactory information processing and determine how these are modulated by affective properties of odors. (jneurosci.org)
We aimed to compare the resting-state structural and functional connectivity (FC) of olfactory neural pathways in patients with nIHH and KS. (researchsquare.com)
On this basis, we explored the olfactory neural pathways through both rsFC and DTI to examine the olfactory processing mechanism of IHH patients. (researchsquare.com)
In neonates, this area is a dense neural sheet, but, in children and adults, the respiratory and olfactory tissues interdigitate. (medscape.com)

WATER THERAPY has been created to stimulate a similar effect in the body, via the olfactory system. (niche-beauty.com)

The limbic system of the brain regulates a number of behaviors that are essential for the survival of all vertebrate species including humans. (frontiersin.org)
In adult humans with history of childhood maltreatment, which is a type of ELA, OB volume was reduced by 20% with a concomitant decrease in their olfactory detection thresholds and problems in identifying odours [ 13 ]. (nature.com)
As humans age, the number of olfactory neurons steadily decreases. (medscape.com)

Therefore, in this review we focus primarily on chemosensation in the rodent and how it relates to innate limbic responses to social conspecific cues such as mating, maternal care, and territorial behaviors as well as non-social defensive responses to predator cues. (frontiersin.org)
These signals, which are not detected consciously as odors by the olfactory system, mediate human autonomic, psychological, and endocrine responses. (medscape.com)

The olfactory system represents one of the oldest sensory modalities in the phylogenetic history of mammals. (medscape.com)

We used event-related functional magnetic resonance imaging (fMRI) in an olfactory version of a classical conditioning paradigm, whereby neutral faces were paired with pleasant, neutral, or unpleasant odors, under 50% reinforcement. (jneurosci.org)
We have reported significant structural and functional disruptions unilaterally at the right junction of the fronto-limbic system in KS patients. (researchsquare.com)
Combining behavioral and functional MRI (fMRI) techniques, I am examining the role of frontoparietal brain regions (and their interaction with limbic regions) in encoding expectations and integrating top-down spatial and emotional information to guide attention towards the salient targets. (psychologicalscience.org)
Our functional fragrance uses olfactory technology to replicate the sensory feeling of being in or around water, formulated with a marine-inspired blend of calming scent notes: seaweed, salt, cardamom and rose. (niche-beauty.com)

The limbic system links external cues possessing emotional, social, or motivational relevance to a specified set of contextual and species-specific appropriate behavioral outputs. (frontiersin.org)

Fracture of the cribriform plate in traumatic settings can disrupt these fine fibers and lead to olfactory dysfunction. (medscape.com)

In this article, we reviewed the evidence that eating, especially high-caloric foods, stimulates the limbic system, initiating Reward Deficiency Syndrome. (frontiersin.org)

Odorants diffuse into the mucous and are transported to the olfactory receptor. (medscape.com)

Our experiments revealed a mechanistic link between deficient gamma activity and behavioral decline in mice and rat models of depression, with the signal changes in the olfactory and connected limbic systems similar to those seen in depressed patients," said corresponding study author Antal Berényi, MD, PhD, adjunct assistant professor in the department of neuroscience and physiology at NYU Langone Health. (genengnews.com)

In this article we review the current understanding of how limbic circuits regulate sexually dimorphic behaviors and how these circuits are established and shaped during pre- and post-natal development. (frontiersin.org)

By implementing go/no-go odour discrimination paradigm, we observed olfactory learning and memory impairments in early life stressed (ELS) male mice. (nature.com)

Since the limbic system is directly connected to parts of the brain which control heart rate, blood pressure, breathing, memory, stress levels and blood circulation, the aroma of essential oils affect all these parts to a great extent. (essentialoil.net)

It affects the limbic system of the brain in all types of ways. (youngliving.com)

Olfactory bulbectomy, an established model of depression that reduces limbic gamma oscillations, suffers from nonspecific effects of structural damage. (genengnews.com)

We do not yet understand the central processing pathways in the olfactory system, especially regarding these disorders. (researchsquare.com)

More specifically in the limbic area of the brain, which is also responsible for generating our emotions and developing memory. (goodcleanlove.com)

The Limbic system, which is home to emotions, is also a link between the right and left brain, and a link between the voluntary and involuntary nervous systems. (57aromas.com)

Recently, also in retrospect, VSBV-1 was shown to be responsible for fatal limbic encephalitis in a zoo animal caretaker after contact with an exotic Prevost's squirrel ( Callosciurus prevostii ) in northern Germany ( 2 ). (cdc.gov)

Anatomy44

Organisms37

Diseases11

Chemicals and Drugs50

Analytical, Diagnostic and Therapeutic Techniques and Equipment15

Psychiatry and Psychology24

Phenomena and Processes35

Disciplines and Occupations3

Information Science3

Health Care2

Hippocampus8

Bulb16

Connected to the limbic system3

Hypothalamus6

Amygdala2

Cortex11

Receptors6

Brain's1

Unique to the olfactory2

Nasal3

Structures3

Sensory neurons1

Epithelium4

Nose2

Smell6

Stimuli2

Nerve5

Nerves1

Rodents2

Processes3

Bulbs1

Basal1

Receptor cells2

Neural4

Stimulate1

Humans3

Responses2

Modalities1

Functional4

Emotional1

Dysfunction1

Stimulates1

Mucous1

Behavioral1

Behaviors1

Paradigm1

Essential oils1

System of the brain1

Structural1

Disorders1

Memory1

Systems1

Responsible1