• The incidence of phototoxicity associated with sparfloxacin appears to be higher than that observed with ciprofloxacin and ofloxacin but less than that reported for fleroxacin, pefloxacin, enoxacin and nalidixic acid. (wikipedia.org)
  • Another difference between the two drugs is that ofloxacin is a category C drug for pregnant women and cefixime is a category B drug. (wisegeek.com)
  • Ofloxacin is a fluorinated 4-quinolone which differs from other fluorinated 4-quinolones in that there is a six member (pyridobenzoxazine) ring from positions 1 to 8 of the basic ring structure. (drugs.com)
  • While both cefixime and ofloxacin effectively eradicate similar strains of bacteria, ofloxacin's different chemical structure and method of killing bacteria make many microbes less resistant to it. (wisegeek.com)
  • There is no specific information comparing use of ophthalmic ofloxacin in the elderly with use in other age groups. (mayoclinic.org)
  • Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of ofloxacin in the elderly. (mayoclinic.org)
  • However, elderly patients are more likely to have age-related heart or kidney problems, or develop severe tendon problems (including tendon rupture), which may require caution and an adjustment in the dose for patients receiving ofloxacin. (mayoclinic.org)
  • Coadministration with ofloxacin may increase risk of CNS stimulation and seizures. (drugs.com)
  • According to the product package insert, ofloxacin is effective against the following microorganisms. (wikipedia.org)