[15] Another PABA derivative, Et-PABA, disrupts estrogenic and androgenic activity. (safecosmetics.org)
Compounds5
Estradiol is one of the more potent of the known estrogenic compounds, identical with the primary estrogenic hormone produced by the human ovary. (drugs.com)
It is believed to have compounds that have estrogenic expression but in significantly reduced potency as human estrogens in the ratio of 1:400. (naturalnews.com)
there is a point to be made claiming that the research is biased, as the lead researcher has a large stake in a company that produces competing products that do not leech estrogenic compounds. (techdirt.com)
There are safety concerns over the estrogenic properties of all parabens but especially two specific compounds, butylparaben and propylparaben. (theecologist.org)
The variability in estrogenic activity among the compounds makes setting acceptable safety standards much harder and as a result a more drawn out process. (theecologist.org)
Antibacterial1
Estrogenic activity, antibacterial action and some pharmacodynamic properties of Cyperus rotundus Linn. (rug.nl)
Hormones2
Their presence in both vertebrates and insects suggests that estrogenic sex hormones have an ancient evolutionary history. (absoluteastronomy.com)
The administration of estrogenic hormones in feed increases the rate of growth in livestock, but concern has been raised about the consumption of meat products containing these hormones. (who.int)
Coumestrol1
The crystal structures of the 17β-HSDcl apo, holo and coumestrol-inhibited ternary complex, and the active-site Y167F mutant reveal subtle conformational differences in the substrate-binding loop that probably modulate the catalytic activity of 17β-HSDcl. (rcsb.org)
Endocrine3
BPA has estrogenic and other endocrine disrupting activities [4] , [5] . (plos.org)
[8] Padimate O may also disrupt endocrine activity. (safecosmetics.org)
A variety of assays have been developed for measure endocrine related activity. (mdpi.com)
Evaluation2
We conclude that evaluation of global estrogenic activity, as opposed to activation of a specific target gene, provides a more accurate read-out for osteoblast stimulation. (bath.ac.uk)
The evaluation of the functional symmetry of the orofacial complex, involves the pattern of the mandibular movement and the masticatory muscles activity. (bvsalud.org)
Stimulation3
As well as inhibiting bone remodelling, this effect may involve stimulation of osteoblast activity, in light of evidence from recent in vivo studies. (bath.ac.uk)
Data from both in vivo and in vitro experiments demonstrated that glabridin and glabrene are similar to estradiol-17β in their stimulation of the specific activity of creatine kinase, although at higher concentrations, but differ in their extent of action and interaction with other drugs. (tau.ac.il)
Raloxifene, in combination with glabridin or estradiol-17β, demonstrated the phenomenon of mutual annihilation of stimulation of creatine kinase specific activity in both epiphysis and diaphysis. (tau.ac.il)
Estrogen6
In Particular, ERGR-mediated GRE-luc activity provides a high signal response to estrogen agonists and SERMs, in a cell context dependent manner closely resembling that observed in vivo. (bath.ac.uk)
To answer this question, we first investigated the ability of ellagic acid to influence the activity of the estrogen receptor subtypes ERalpha and ERbeta in HeLa cells. (nutrimedical.com)
At low concentrations (10(-7) to 10(-9) M), this compound displayed a small but significant estrogenic activity via ERalpha, whereas it was a complete estrogen antagonist via ERbeta. (nutrimedical.com)
In some species (e.g., bovine), evidence indicates that decreases in IGFBP-4 and -5 levels in estrogen-dominant preovulatory follicles are likely due, in part, to increased protease activity, whereas lower levels of IGFBP-2 are not due to increased proteolysis. (bioone.org)
The PABA derivative Padimate O appears to be weakly anti-estrogenic (meaning it suppresses estrogen pathways). (safecosmetics.org)
They have estrogenic activity, cause toxicity in livestock as feed contaminant, and have been used as anabolic or estrogen substitutes. (bvsalud.org)
Antioxidant4
Antioxidant and apoptosis-inducing activities of ellagic acid. (nutrimedical.com)
BACKGROUND: Antioxidant, antiproliferative and apoptosis inducing activities of a natural polyphenolic compound, ellagic acid, were studied. (nutrimedical.com)
Activities of antioxidant enzymes, superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX) were measured in ellagic acid-treated V79-4 cells. (nutrimedical.com)
CONCLUSION: Ellagic acid exhibited both antioxidant activity in V79-4 cells and apoptosis-inducing activity in HOS cells through the up-regulation of Bax and activation of caspase-3. (nutrimedical.com)
Pathways1
The aim of this article is to discuss the regulatory pathways by which E2 orchestrates the activity of several components of mitochondrial dynamics in the cardiovascular and nervous systems in health and disease. (ucl.ac.uk)
Extract1
Antiviral activity of ginseng extract against respiratory syncytial virus infection. (naturalnews.com)
Ovary1
Whether the hormonal control of PAPP-A production/activity by the ovary differs between monotocous and polytocous animals will require further study. (bioone.org)
TCDD1
TCDD for every step of the mechanism described for 2,3,7,8-TCDD carcinogenesis in humans including receptor binding, gene expression, protein activity changes, cellular replication, oxidative stress, promotion in initiation-promotion studies and complete carcinogenesis in laboratory animals. (who.int)
Vivo1
Some of the estrogenic contaminants of technical grade methoxychlor are the same as those formed by metabolism in vivo (Bulger et al. (cdc.gov)
Protein2
For apoptotic inducing activity, human osteogenic sarcoma (HOS) cell proliferation, chromosomal DNA degradation and changes in apoptosis-related protein levels were measured. (nutrimedical.com)
This protease activity has recently been ascribed to serine metalloprotease(s), including pregnancy-associated plasma protein-A (PAPP-A), which was first detected in human follicular fluid nearly 20 yr ago. (bioone.org)
Compound1
Whether this compound has estrogenic/antiestrogenic activity, however, remains largely unknown. (nutrimedical.com)
Tissue1
Studies performed on rats and on thyroid tissue samples suggest that PABA may disrupt thyroid activity. (safecosmetics.org)
Chemicals2
An environmental group claims that BPA-free containers can still leach out chemicals with "estrogenic activity" under normal use conditions. (techdirt.com)
But there are a lot of chemicals that might exhibit "estrogenic activity" - and be perfectly harmless at low concentrations. (techdirt.com)
Increases1
Indeed, transcriptional responses to SERMs in osteoblast-like cells were considerably greater with the ERGR/GRE-luc than the ER alpha/ERE-luc system, 4-HT inducing 300 and 25% increases in reporter activity respectively. (bath.ac.uk)
Significantly1
SOD, CAT and GPX activities were significantly increased in ellagic acid-treated V79-4 cells. (nutrimedical.com)
Biological2
It is important to recognize that because of the biological activity of these contaminants, dose-response relationships obtained using technical grade methoxychlor may not be directly applicable to pure methoxychlor. (cdc.gov)
Wedelolactone possesses a wide range of biological activities and is used for the treatment of hepatitis and cirrhosis, as an. (diagnose-me.com)
Cellular1
We investigated cellular compartmentalisation of these constructs by fluorescence microscopy, nuclear mobility by fluorescence recovery after photobleaching (FRAP), and global activation of estrogenic transcription using a ERE-luc reporter. (bath.ac.uk)
Human1
1999. Transactivation activity of human, zebrafish, and rainbow trout aryl hydrocarbon receptors expressed in COS-7 cells: Greater insight into species differences in toxic potency of polychlorinated dibenzo- p -dioxin, dibenzofuran, and biphenyl congeners. (cdc.gov)
Hormonal1
The HPG axis is primarily responsible for governing all the hormonal events related to reproductive activity. (intechopen.com)
Research1
Some research links PABA with thyroid-disrupting activity, raising concerns about long-term health effects. (safecosmetics.org)
Products1
Most of a sample of 455 commercially available products tested positive for EA [estrogenic activity]. (culturechange.org)
Specific3
Both glabridin and glabrene stimulated creatine kinase specific activity in diaphyseal bone and epiphyseal cartilage of prepubertal female rats. (tau.ac.il)
Daily feeding (3-14 days) of prepubertal female rats with glabridin, estradiol-17β or their combination, also stimulated creatine kinase specific activity. (tau.ac.il)
Glabridine, similarly to estradiol-17β, also stimulated creatine kinase specific activity in ovariectomized female rats. (tau.ac.il)
Components1
[6] Morohoshi K, Yamamoto H, Kamata R, Shiraishi F, Koda T, and Morita M. "Estrogenic activity of 37 components of commercial sunscreen lotions evaluated by in vitro assays. (safecosmetics.org)
Greater2
Increased IGFBP-4 and -5 protease along with lower amounts of IGFBP-4 binding activity and greater amounts of free IGF-I are some of the earliest developmental changes documented in bovine growing antral follicles. (bioone.org)
Results: There was greater symmetry of the masseter muscle electrical activity after ultrasound associated with stretching (p=0.03). (bvsalud.org)
Levels1
2006). The serum levels of workers engaged in sealant removal were 2-10 times higher at the end of these activities than they had been one year before (Kontsas et al. (who.int)
Higher1
The muscle electrical activity at rest is higher in TMD patients, while the EMG potentials during the voluntary maximal contraction are reduced, compared to healthy subjects. (bvsalud.org)
High1
RESULTS: Ellagic acid showed high DPPH radical scavenging and lipid peroxidation inhibition activities. (nutrimedical.com)
Cells2
SERMs caused a modest increase in ERE-luc activity in osteoblast-like cells (but not in breast cells), and a reduction in nuclear mobility in breast (but not osteoblast-like) cells. (bath.ac.uk)
Interestingly, SERMs increased both cytoplasmic to nuclear translocation of ERGR-GFP, and GRE-luc reporter activity, in osteoblast-like (but not breast) cells. (bath.ac.uk)