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  • distal esophagus
  • These groups are (1) gastric adenocarcinomas, (2) adenocarcinomas of the distal esophagus and GE junction with background intestinal metaplasia, and (3) adenocarcinomas of the distal esophagus and GE junction without background intestinal metaplasia. (redorbit.com)
  • Expression of PIgR and CDX2 in nonneoplastic mucosa, intestinal metaplasia, and adenocarcinomas was examined by immunohistochemistry in 42 cases: 14 gastric and 28 from the distal esophagus and GE junction, including 13 with esophageal or GE junction intestinal metaplasia. (redorbit.com)
  • PIgR is uniformly expressed in intestinal metaplasia and in a subgroup of adenocarcinomas of the distal esophagus, GE junction, and stomach. (redorbit.com)
  • citation needed] In most cases of Boerhaave's syndrome, the tear occurs at the left postero-lateral aspect of the distal esophagus and extends for several centimeters. (wikipedia.org)
  • stratified squamous e
  • It is characterized by the replacement of the normal stratified squamous epithelium lining of the esophagus by simple columnar epithelium with goblet cells (which are usually found lower in the gastrointestinal tract ). (wikipedia.org)
  • The mucosa, which is the inner most layer and lining of the esophagus, is composed of stratified squamous epithelium, lamina propria, and muscularis mucosae. (wikipedia.org)
  • chronic
  • Adult with progressive dysphagia to solids and eventually to all foods, caused by a narrowing of the lower esophagus, usually as a result of chronic inflammatory disease. (brainscape.com)
  • Chronic diseases might include congenital diseases such as Zenker's diverticulum and esophageal webbing, and oesophageal motility disorders including the nutcracker oesophagus, achalasia, diffuse oesophageal spasm, and oesophageal stricture. (wikipedia.org)
  • acute
  • Acute disease might include infections such as oesophagitis, trauma caused ingestion of corrosive substances, or rupture of veins such as oesophageal varices, Boerhaave syndrome or Mallory-Weiss tears. (wikipedia.org)
  • columnar
  • In this paper, Barrett suggested that the finding of an oesophagus lined with columnar epithelium (rather than the usual squamous epithelium) was due to the presence of a congenitally shortened oesophagus leading to a tubular portion of stomach being trapped in the chest. (wikipedia.org)
  • duodenum
  • Diagnosis requires endoscopy (more specifically, esophagogastroduodenoscopy , a procedure in which a fibreoptic cable is inserted through the mouth to examine the esophagus, stomach, and duodenum ) and biopsy . (wikipedia.org)
  • Destruction of the myenteric plexus of the esophagus, duodenum, colon and ureter caused by a flagellate protozoa. (brainscape.com)
  • mucosa
  • Thin membranes of normal esophageal tissue consisting of mucosa and submucosa that can partially obstruct the esophagus. (brainscape.com)
  • The esophagus is made up of four different layers: serosa, muscularis externa, submucosa, and the mucosa. (wikipedia.org)
  • The wall of the esophagus from the lumen outwards consists of mucosa, submucosa (connective tissue), layers of muscle fibers between layers of fibrous tissue, and an outer layer of connective tissue. (wikipedia.org)
  • commonly
  • Congenital esophageal webs commonly appear in which segment of the esophagus? (brainscape.com)
  • Spontaneous perforation of the esophagus most commonly results from a full-thickness tear in the esophageal wall due to a sudden increase in intraesophageal pressure combined with relatively negative intrathoracic pressure caused by straining or vomiting (effort rupture of the esophagus or Boerhaave's syndrome). (wikipedia.org)
  • In case of iatrogenic perforation common site is cervical esophagus just above the upper sphincter whereas spontaneous rupture as seen in Boerhaave's syndrome perforation commonly occurs in the lower (1/3)rd of esophagus. (wikipedia.org)
  • The esophagus (American English) or oesophagus (British English) (/ɪˈsɒfəɡəs/), commonly known as the food pipe or gullet, is an organ in vertebrates through which food passes, aided by peristaltic contractions, from the pharynx to the stomach. (wikipedia.org)
  • Diagnosis
  • In addition to his work on oesophageal disease, Barrett also worked with Leonard Dudgeon, Professor of Pathology at the University of London, on the cytology of sputum in the diagnosis of pulmonary malignancy. (wikipedia.org)
  • mucosal
  • In healthy (immunocompetent) persons, candidiasis is usually a localized infection of the skin, fingernails or toenails (onychomycosis), or mucosal membranes, including the oral cavity and pharynx (thrush), esophagus, and the genitalia (vagina, penis, etc. (wikipedia.org)
  • Infections
  • In immunocompromised individuals, Candida infections in the esophagus occur more frequently than in healthy individuals and have a higher potential of becoming systemic, causing a much more serious condition, a fungemia called candidemia. (wikipedia.org)
  • rupture
  • Spontaneous effort rupture of the cervical esophagus, leading to localized cervical perforation, may be more common than previously recognized and has a generally benign course. (wikipedia.org)
  • As the intra-oesophageal pressure increases, the bolus within the oesophagus has nowhere to go superiorly (as the cricopharyngeus fails to relax) which causes the oesophagus to rupture. (wikipedia.org)
  • thoracic
  • Barrett was a lecturer in surgery for the University of London (1935-1970), Surgeon to King Edward VII Sanatorium in Midhurst, Sussex (1938-1970), and Consulting Thoracic Surgeon to both the Royal Navy and the Ministry of Social Security (1944-1970). (wikipedia.org)
  • In humans, the esophagus generally starts around the level of the sixth cervical vertebra behind the cricoid cartilage of the trachea, enters the diaphragm at about the level of the tenth thoracic vertebra, and ends at the cardia of the stomach, at the level of the eleventh thoracic vertebra. (wikipedia.org)
  • The lower esophagus lies behind the heart and curves in front of the thoracic aorta. (wikipedia.org)
  • The thoracic duct, which drains the majority of the body's lymph, passes behind the esophagus, curving from lying behind the esophagus on the right in the lower part of the esophagus, to lying behind the esophagus on the left in the upper esophagus. (wikipedia.org)
  • passes
  • From the bifurcation of the trachea downwards, the esophagus passes behind the right pulmonary artery, left main bronchus, and left atrium. (wikipedia.org)
  • contrast
  • If esophageal perforation is suspected, even in the absence of physical findings,chest xray, water soluble contrast radiographic studies of the esophagus and a CT scan should be promptly obtained. (wikipedia.org)