Ocular tumor patients. Medical search. Frequent questions

A biopsy of the tumor is rarely needed to diagnose intraocular melanoma. (cancer.gov)
Intraocular melanoma of the iris is usually a small tumor that grows slowly and rarely spreads to other parts of the body. (cancer.gov)
Major successes have been achieved in breast cancer metastases, cholangiocarcinoma, neuroendocrine metastases, and ocular melanoma. (diagnosticimaging.com)
Researchers at the Third Annual Symposium on Liver-Directed Microsphere Therapy presented compelling pretreatment and post-treatment PET scans of patients who received internal radiotherapy for unresectable and chemorefractory tumors from breast, colon, bile duct, pancreatic, esophageal, neuroendocrine, and melanoma cancers. (diagnosticimaging.com)
Ocular melanoma is unique in that it almost always metastasizes only to the liver, which in turn is the most common reason for patient death, as so few treatment options are available. (diagnosticimaging.com)
Conversely, echoes with low intensity are common in undifferentiated and more malignant tumors (lymphoma-lymphosarcomas, feline diffuse melanoma. (vin.com)
Accuracy of diagnosis of choroidal melanomas in the Collaborative Ocular Melanoma Study. (helsedirektoratet.no)
Hyperthermic isolated hepatic perfusion using melphalan for patients with ocular melanoma metastatic to liver. (helsedirektoratet.no)
Baseline echographic characteristics of tumors in eyes of patients enrolled in the Collaborative Ocular Melanoma Study: COMS report no. 29. (helsedirektoratet.no)
The Collaborative Ocular Melanoma Study Group (2001). (helsedirektoratet.no)
Assessment of metastatic disease status at death in 435 patients with large choroidal melanoma in the Collaborative Ocular Melanoma Study (COMS): COMS report no. 15. (helsedirektoratet.no)
Efficacy and Safety of Nivolumab Alone or in Combination With Ipilimumab in Patients With Mucosal Melanoma: A Pooled Analysis. (helsedirektoratet.no)
Eye melanoma begins when melanocytes change and grow out of control, forming a mass called a tumor. (cancer.net)
This guide is about primary eye melanoma, which means the tumor started in the eye. (cancer.net)
Specially trained ophthalmologists called ocular oncologists can diagnose and treat eye melanoma. (cancer.net)
These tumors are often larger and are more likely to spread outside the eye compared with iris melanoma (see below). (cancer.net)
As the tumor enlarges, it may cause distortion of the pupil (iris melanoma), blurred vision (ciliary body melanoma), or markedly decreased visual acuity caused by secondary retinal detachment (choroidal melanoma). (cigna.com)
Ciliary body melanoma is a rare tumor. (medscape.com)
Ciliary body melanoma is a subtype of uveal melanoma, the most common primary malignant tumor of the eye. (medscape.com)
Patients who die from ciliary body melanoma die because of distant metastasis rather than local spread. (medscape.com)
BACKGROUND Patients with uveal melanoma can be treated by a number of modalities. (bmj.com)
A short, patient based questionnaire was developed and validated for evaluating outcomes following treatment for uveal melanoma. (bmj.com)
The reliability and validity of the three MOOD scores (total, vision, impact) were evaluated in 176 patients who had been treated for uveal melanoma (75 brachytherapy, 78 proton beam radiotherapy, 23 enucleation). (bmj.com)
CONCLUSIONS The MOOD is a practical and scientifically sound patient based measure which can be used in research and audit to evaluate outcomes following treatment for uveal melanoma. (bmj.com)
Enucleation was the standard treatment for uveal melanoma which has excellent local tumour control rates, but it involves sacrificing the eye. (bmj.com)
Delcath Systems, Inc. (Nasdaq: DCTH), a medical technology company testing its proprietary treatment method for primary and metastatic cancers to the liver, announced today that it has exceeded 90% enrollment reaching 85 patients for its pivotal Phase III Metastatic Melanoma Trial. (news-medical.net)
This clinical study is testing the Delcath PHP System(TM) for the regional delivery of melphalan to the liver to treat patients with metastatic cutaneous and ocular melanoma who have unresectable tumors in the liver. (news-medical.net)
Already, they have made major discoveries that have improved the diagnosis and treatment of many retinal diseases, including AMD, inherited retinal disorders, diabetic retinopathy, and ocular melanoma. (masseyeandear.org)
We have achieved international recognition for our research and treatment of ocular melanoma. (uclahealth.org)
Ocular cancers, such as ocular melanoma and retinoblastoma, are particularly challenging to treat. (justia.com)
Who treats ocular melanoma? (aimatmelanoma.org)
Comparison of Tumor Size and Gene Expression at Presentation in Uveal Melanoma Patients before and during the COVID-19 Pandemic. (cdc.gov)
To assess the influences of race/ethnicity, sex, tumor stage, tumor thickness, and anatomic site on mucosal melanoma survival estimates. (cdc.gov)
Poorer survival in patients with mucosal melanoma was observed in relation to stage and anatomic site, but not tumor thickness (i.e. (cdc.gov)

Patients with corneal and conjunctival tumors improved their ocular symptoms, visual acuity , and the emotional component of their quality of life after surgical excision of the tumor . (bvsalud.org)
The patient had no other ocular signs or symptoms, and her general condition was otherwise good. (cdc.gov)
Review of past cases, patients often do not exhibit many symptoms or obtain a diagnosis until they are around 20 to 40 years old. (wikipedia.org)
If the patient does show symptoms, it is most likely due to pressure from growth of the tumor. (wikipedia.org)
Carcinoid tumor in the liver treated with microspheres has demonstrated excellent response and reversal of clinical symptoms. (diagnosticimaging.com)
The patient experienced 70% reduction in his serum tumor marker value and significant reduction in carcinoid symptoms after a single microsphere treatment. (diagnosticimaging.com)
Ocular tumor identification in dogs and cats often entails diagnosis difficulties, as patients are frequently brought to consultation with rather advanced symptoms and lack of clearness of the structures. (vin.com)
The SF-36, the current gold standard generic measure of quality of life, has been shown to be sensitive to "blurred vision" as a symptom, but it may not be sensitive to other ocular symptoms or to a single eye disease. (bmj.com)
Clinically, patients usually present with focal neurological deficits, signs of increased intracranial pressure or neuropsychiatric symptoms. (pathologyoutlines.com)
None of the patients developed ocular symptoms aggravation after the procedure. (egms.de)
Therefore, the purpose of management is essentially to prevent ocular symptoms in addition to correcting the aesthetic defects, especially for the patient with severe and permanent facial paralysis. (airitilibrary.com)
In general, HRQoL is worse in patients with CD than in healthy individuals, particularly in the presence of cardiovascular and/or gastrointestinal symptoms. (scielo.br)
ABSTRACT Symptoms in post-COVID-19 patients who require hospitalization can persist for months, significantly affecting their health-related quality of life (HRQoL). (scielo.br)
Enucleation is recommended for large uveal melanomas that cannot be effectively treated with radiation, or that are causing symptoms like blindness or pain or tumors with significant extensions outside the eye. (aimatmelanoma.org)

Here, we report a retroocular D. repens nematode infection in a patient in Russia that illustrates the difficulties in clinical management and the inherent risks of surgical procedures to remove the worms. (cdc.gov)
A 64-year-old Hispanic woman with a lesion typical for OSSN in her left eye was followed up with multiple clinical examinations and ocular surface photographs to document changes over time with A. vera-based topical treatment. (nih.gov)
Adjunctive courses were repeated until clinical and cytological tumour regression. (bmj.com)
Ocular oncology has long been a clinical interest of mine, and there are only a few ophthalmologists in the country who diagnose and treat ocular cancer. (castleconnolly.com)
Each tumor type provides a series of echoes which may become rather characteristic, hence they are very helpful in clinical diagnosis. (vin.com)
Ren MY, Li J, Wu YX, Li RM, Zhang C, Liu LM, Wang JJ, Gao Y. Clinical characteristics and prognosis of orbital solitary fibrous tumor in patients from a Chinese tertiary eye hospital. (wjgnet.com)
Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent. (wjgnet.com)
A number of biologic agents have either been approved or are in clinical trials for the treatment of systemic inflammatory diseases such as multiple sclerosis, rheumatoid arthritis, psoriasis, and Crohn's disease, so it is only natural that many of these agents have been used off label in patients with more severe and sight-threatening uveitis. (ophthalmologytimes.com)
The aim of the study was to explore clinical utility of image-guided endoscopy for orbital tumors biopsy. (egms.de)
Eligible patients benefit from access to these treatments through clinical trials. (uclahealth.org)
In conclusion, assessment of HRQoL can provide important information about the health status of patients with CD, and its use in clinical practice is warranted. (scielo.br)
In conclusion, these findings may aid in clinical management and should be considered in the aftercare of patients. (scielo.br)
Patients with mpox benefit from supportive care and pain control that is implemented early in the illness ( Clinical Considerations for Pain Management of Mpox ). (cdc.gov)
Presence of Anti-MDA5 Antibody and Its Value for the Clinical Assessment in Patients With COVID-19: A Retrospective Cohort Study. (cdc.gov)
Patients treated under the CED paradigm should be covered by insurance as long as they are enrolled either in an institutional review board-approved clinical trial or in a multi-institutional patient registry that follows Medicare requirements for CED. (medscape.com)
The patient met the clinical criteria set forth by Cullen in 1987 for MCS. (cdc.gov)

Radiation therapy is an important part of treating many different head and neck tumors, and is often used after surgery. (lifeextension.com)
Increased activity (expression) of the JAG1 gene has been linked to certain cancers, including breast cancer and head and neck tumors. (medlineplus.gov)

Analysis of ocular surface and quality of life in patients with corneal and conjunctival tumors. (bvsalud.org)
To evaluate the impact of corneal and conjunctival tumors on the ocular surface and quality of life of patients before and after surgical treatment . (bvsalud.org)
This prospective study conducted a preoperative and 30- and 90-day postoperative assessment of patients diagnosed with conjunctival and corneal tumors . (bvsalud.org)
Background/aims The aim of this study was to evaluate the long-term corneal toxicity of topical chemotherapy with 1% 5-fluorouracil (5-FU) as a sole or adjuvant treatment of ocular surface squamous neoplasia (OSSN). (bmj.com)
1 However, ocular radiotherapy is not without morbidity 4 5 and charged particle beam radiotherapy 6-12 is associated with side effects including keratitis, cataract, scleral and corneal necrosis, radiation retinopathy, radiation optic neuropathy, retinal detachment, phthisis, rubeosis iridis, and glaucoma. (bmj.com)
There are a multitude of treatments for corneal disease (also called ocular surface disease). (dukehealth.org)

The patients ' visual acuity improved significantly at 1 month and 3 months (p=0.018 and p=0.036, respectively). (bvsalud.org)
Children with brain tumors can present visual impairments like decreased visual acuity and contrast sensitivity (CS), loss of color vision, and visual field loss such as hemianopias ( 1 - 5 ). (frontiersin.org)
The ocular examination disclosed a visual acuity of 20/20 in each eye, equally round and reactive pupils with no afferent pupillary defect, and eyes soft to palpation bilaterally. (aao.org)
The 20 patients with poor visual acuity (≤ 20/400) received 50,000 to 200,000 RPE cells, and the six patients with better vision (≤ 20/100) received 100,000 cells. (medscape.com)
Of the 26 patients, 24 (92%) developed areas of subretinal pigmentation that did not correlate with cell dose or visual acuity outcomes. (medscape.com)
The table shows the 12-month and 24-month best-corrected visual acuity (BCVA) response (10+ letter increase) for 18 patients with AMD and Stargardt disease in the treated and untreated eyes (Table). (medscape.com)

citation needed] Intracranial epidermoid tumors are slow growing lesions, which may recur after incomplete removal during surgery, although it will most likely take many years. (wikipedia.org)
Cutaneous manifestations can occur in up 75% of patients with Behcet disease and can range from acneiform lesions, to nodules and erythema nodosum. (medscape.com)
HSP-65, found in high concentrations in oral ulcers and active skin lesions in patients with Behçet disease, has also been demonstrated to stimulate production of antibodies that exhibit cross-reactivity with streptococcal species present in the mouth. (medscape.com)
In 1938, Cushing and Eisenhardt first used the term "meningioma" to describe these lesions and introduced it as a separate category of extraparenchymal tumors. (medscape.com)
and 80-90% of these patients develop contralateral tumors and intraparenchymal CNS lesions, with invasion of the subretinal pigment epithelial space and vitreous. (pathologyoutlines.com)
We present the group of patients with intraorbital mass lesions in whom transnasal endoscopic biopsy was performed using a videooptic (Medtronic Stealth Station Treon plus) and electromagnetic (Medtronic Fusion ENT Navigation) neuronavigation systems. (egms.de)
Those who evaluate patients with MCS are reminded that meningiomas and other intracranial mass lesions can affect olfaction, and that patients with MCS can have treatable intracranial abnormalities. (cdc.gov)

This paper was partially presented at the International Congress of Ocular Oncology, 8-12 September 2009, Cambridge, UK. (bmj.com)
He is one of the few retina specialists in the United States who treats cancers of the eye (ocular oncology). (castleconnolly.com)
He is a member of professional organizations that include the American Medical Association, American Academy of Ophthalmology, International Society of Ocular Oncology, and The American Society of Retina Specialists. (castleconnolly.com)
This accelerated approval of mirvetuximab soravtansine for [FRα-positive, platinum-resistant epithelial ovarian, fallopian tube, or primary peritoneal cancer] is incredibly meaningful for patients who have this cancer," Ursula A. Matulonis, MD , Chief of the Division of Gynecologic Oncology and the Brock-Wilson Family Chair at Dana-Farber Cancer Institute and co-leader of the SORAYA study. (ascopost.com)
Dr. Cooper is the program director of the radiation oncology resident training program at MUSC, and enjoys working with residents to both improve the care of his patients and educate future radiation oncologists. (wellness.com)
Ocular oncology and pathology 2023 0 0. (cdc.gov)
A vision of immuno-oncology: the Siena think tank of the Italian network for tumor biotherapy (NIBIT) foundation. (cdc.gov)

Internal radiotherapy with yttrium-90 microspheres has demonstrated consistent and useful tumor reductions. (diagnosticimaging.com)
Combined proton beam radiotherapy and transpupillary thermotherapy for large uveal melanomas: a randomized study of 151 patients. (helsedirektoratet.no)
To date, the most advanced photon beam delivery method is intensity-modulated (IM) radiation therapy (IMRT), which can deliver higher doses of radiotherapy to tumour targets while reducing the dose delivered to selected normal tissues. (nature.com)
Of course, the risk of second malignancy is also a risk in adults, but the fact that the median age of adult cancer patients at diagnosis is in the seventh decade, that second malignancies after radiotherapy are uncommon in adults, and that they usually manifest 10-15 years after treatment make them less of a concern. (nature.com)
1 2 Primary tumour control rates are excellent: 100% for those without extraocular extension treated by enucleation, 95% for brachytherapy, and 98% 3 or more for charged particle radiotherapy. (bmj.com)
He underwent a tumor resection followed by postoperative radiotherapy due to squamous cell carcinoma of the right external auditory canal. (airitilibrary.com)

This patient, who presented with right uveal cancer (A) and synchronous liver metastases (B), had a complete response within six months of microsphere treatment in the liver (C), which contained persistent cancer despite 13 prior transcatheter arterial chemoembolization procedures. (diagnosticimaging.com)
They can be classified as anterior uveal melanomas when the tumor arises in the iris and as posterior uveal melanomas when it arises in either the choroid or the ciliary body. (medscape.com)
External-beam charged particle radiation (also called proton-beam radiation), which uses a machine outside of the body to deliver laser beams of charged particles that damage the tumor cells in the eye, is another common approach that may be used to treat large uveal tumors or those growing near the optic nerve. (aimatmelanoma.org)
Stereotactic radiosurgery , where a machine is used to deliver precisely focused beams of high doses of radiation to a small, targeted area containing the tumor cells is also sometimes used to treat large uveal melanomas. (aimatmelanoma.org)

Methods: A nested case control study was conducted among 131 patients with COVID-19 (40 COVID-19 patients with Pulmonary embolism and 91 COVID-19 patients with no PE) who were on follow up from May, 2021 to May, 2022. (bvsalud.org)

Pictures may be taken over time to keep track of changes in the size of the tumor. (cancer.gov)

The mean age at diagnosis of retinal capillary hemangioma in VHL disease is approximately 25 years, and most patients present between the ages of 10 and 40 years. (eyecancer.com)
In this paper a variety of intraocular, orbital and surface tumors are reviewed with their key sign of diagnosis and current treatment modalities. (banglajol.info)
Though most of these tumor present at tertiary eye hospital, the overall knowledge about these tumors can help ophthalmologists in diagnosis and proper referral. (banglajol.info)
Its metastatic potential depends on the phenotype of the tumor cells, and it frequently disseminates before diagnosis. (medscape.com)
Primary diffuse large B-cell lymphoma of the central nervous system is a rare tumor that b y definition, arises exclusively in the CNS with no obvious lymphoma elsewhere at diagnosis. (pathologyoutlines.com)
However, nearly all tumors have a background of reactive T cells that may lead to an erroneous diagnosis of T cell lymphoma. (pathologyoutlines.com)
Histopatological diagnosis of the intraorbital tumors is of crucial value for planning further therapy. (egms.de)
The present disclosure is directed to methods and compositions for the diagnosis and/or treatment of tumors, such as ocular tumors, using virus-like particles conjugated to photosensitive molecules. (justia.com)
The present disclosure provides, at least in in part, methods and compositions for detecting and/or selectively targeting tumor cells, for example, for the diagnosis and/or treatment of cancer (e.g., ocular cancer). (justia.com)
BACKGROUND: The concurrent diagnosis of meningioma with increased intracranial pressure has not been reported previously in a patient who meets diagnostic criteria for multiple chemical sensitivities (MCS). (cdc.gov)

To report a case of ocular surface squamous neoplasia (OSSN) that resolved with topical Aloe vera eye drop treatment. (nih.gov)

Even histologically proven malignant tumors typically do not show ocular invasion or metastasis. (thieme-connect.com)
Echo intensity is the most important piece of information provided by analysis in Mode A, as the most differentiated and least malignant tumors provide echoes with higher intensity (melanomas and adenomas). (vin.com)

and (2) plaque brachytherapy, a type of radiation therapy, where a thin piece of metal (e.g., gold) with radioactive seeds covering one side is sewn onto the outside wall of the eye with the seeds aimed at the tumor. (justia.com)
Radiation retinopathy has been reported to occur in 10-63% of patients treated with plaque brachytherapy, and the mean time from treatment to the development of maculopathy is approximately 25.6 months. (justia.com)
He has also been instrumental in developing programs for MR guided interstitial brachytherapy for gynecologic malignancies, eye plaque brachytherapy for ocular tumors, interstitial brachytherapy for keloids and breath hold treatments for lymphomas of the chest and abdominal radiosurgery. (wellness.com)
Brachytherapy involves implanting a small disk containing radioactive material into the eye socket near the base of the tumor and removing it after several days. (aimatmelanoma.org)

Retinal capillary "Vvon Hippel" hemangioma is one of the most common and often the earliest manifestations of VHL disease and, therefore, ophthalmologists are frequently involved in the care of patients with this disease. (eyecancer.com)
The MOOD showed good content validity, as assessed by review by ophthalmologists and patients. (bmj.com)

Radioactive microsphere therapy is gaining in popularity among specialists who deal with both primary and metastatic solid tumors in the liver. (diagnosticimaging.com)
The main efficacy outcome measures were investigator-assessed overall response rate and duration of response evaluated according to Response Evaluation Criteria in Solid Tumors version 1.1. (ascopost.com)

This type of lymphoma represents 1% of NHLs, 1% of intracranial tumors, and less than 1% of intraocular tumors. (medscape.com)
See The Case of the Middle-Aged Woman with Sudden Unilateral Vision Loss , a Critical Images slideshow, to help identify and treat malignant intraocular tumors. (medscape.com)
This type of lymphoma is estimated to represent 1% of NHLs, 1% of intracranial tumors, and less than 1% of intraocular tumors. (medscape.com)

citation needed] The chances of intracranial epidermoids is about 1% of all brain tumors. (wikipedia.org)
The Ocular presentation of intracranial epidermoid tumors. (wikipedia.org)

She emphasises in particular the passionate cooperation between ophthalmological specialists, radiation physicists, and radiation therapists as well as with the oncologists who pioneered successful proton treatment for patients. (charite.de)
Depending on individual patient cases, both medical oncologists and radiation oncologists can play essential roles in treating ocular cancer. (castleconnolly.com)

But there was no recurrence of CIN/carcinoma in patients who had received a complete tumor resection initially. (thieme-connect.com)
Various surgical approaches have been developed to maximize tumor resection while preserving important neurovascular structures. (medscape.com)

This benign tumor of the brain is made up of normal skin cells (stratified epithelial lining) on the outside, and fatty acids and keratin are on the inside of the tumor or sac. (wikipedia.org)
A benign tumor means the tumor can grow but will not spread. (cancer.net)

Ever since ocular tumour treatments began, every treatment protocol as well as the post-operative care and follow-ups have been documented in order that predictions of long-term outcomes can be made. (charite.de)
The patient refused biopsy of her lesion and traditional treatments and, instead, initiated using A. vera eye drops 3 times daily. (nih.gov)
Observation, surgery, and radiation all are considered among the potential treatments when evaluating patients with meningioma. (medscape.com)
As none of the different treatments offer a survival advantage, a key factor in choosing among treatments is their differential impact on patients' quality of life. (bmj.com)
Doctors also consider the age, overall health, and preferences of the patient in determining what treatments are most appropriate. (aimatmelanoma.org)

In humans, D. repens worms cause subcutaneous dirofilariasis, characterized by the development of benign subcutaneous nodules that mimic skin carcinomas ( 1 ), and ocular dirofilariasis in orbital, eyelid, conjunctival, retroocular, and intraocular locations ( 2 ). (cdc.gov)

Hence, all patients with ocular lymphoma should have a complete workup to rule out systemic lymphoma. (medscape.com)
The systemic manifestations of VHL are multiple and include CNS hemangiomas of the brain and spinal cord, renal cell carcinomas, renal cysts, pheochromocytomas, pancreatic cysts, islet cell tumors, epididymal cystadenomas, endolymphatic sac tumors of the inner ear, and adnexal papillary cystadenomas of the broad ligament. (eyecancer.com)
I refer high-risk patients to an oncologist colleague at the University of Arizona for ongoing systemic tumor surveillance. (castleconnolly.com)
On November 14, the U.S. Food and Drug Administration (FDA) granted accelerated approval to mirvetuximab soravtansine-gynx (Elahere) for adult patients with folate receptor alpha (FRα)-positive, platinum-resistant epithelial ovarian, fallopian tube, or primary peritoneal cancer, who have received one to three prior systemic treatment regimens. (ascopost.com)

Depending on the site of involvement, ocular lymphoma can be intraocular, and adnexal. (medscape.com)
Retinal capillary hemangioma usually manifests as a solitary tumor, but approximately one-third of patients have multiple retinal hemangiomas, and up to half of patients have bilateral involvement. (eyecancer.com)
[ 3 ] The treatment approach depends on the individual patient, severity of disease, and major organ involvement (see Treatment and Medication . (medscape.com)
Sphenoid wing meningiomas also are known as "orbitosphenoid meningiomas," "meningiomas en plaque of the sphenoid wing," and "sphenoid wing meningiomas with osseous involvement. (medscape.com)
The orbital involvement of the tumor causes significant proptosis of the affected eye. (medscape.com)
Access to oral tecovirimat is also available for patients with mpox who meet eligibility criteria (e.g., have severe disease or involvement of anatomic areas that might result in serious sequelae or are at high risk for severe disease) under CDC's expanded access Investigational New Drug (EA-IND) protocol. (cdc.gov)

Central nervous system tumors are the second most common malignancies in childhood ( 1 ). (frontiersin.org)
We also assessed whether the ABO/Rh factor had any effect on prognosis, agressive features and advanced stage of thyroid malignancies.Methods: Medical records of patients who underwent thyroidectomy between December 2006 and September 2014 were evaluated retrospectively. (endocrine-abstracts.org)

A team at Charité - Universitätsmedizin Berlin and the Helmholtz-Zentrum Berlin (HZB) has now treated its 3000th ocular tumour patient with an individualised proton radiation protocol. (charite.de)
Together with medical staff, the HZB team has accomplished outstanding work for years in offering ocular tumour treatment using high-quality proton radiation", says Prof. Anke Kaysser-Pyzalla, Scientific Director of HZB. (charite.de)
When pituitary tumors are surgically inaccessible or recurrent, conventional radiation therapy or Gamma Knife (stereotactic) radiosurgery can be used. (tuftsmedicalcenter.org)
Tumour control is achieved by radiation-induced damage to DNA, which ultimately causes tumour cell death. (nature.com)
In vivo , however, lethal tumour doses are not always achievable because of radiation-induced morbidity in normal tissues. (nature.com)
A study of head and neck cancer patients who received radiation therapy found that stroke rates were five times greater than expected. (lifeextension.com)
For cancer patients treated with radiation therapy who later die of a stroke, the official cause of death is stroke, even though the cancer radiation therapy most probably caused the stroke. (lifeextension.com)
The government brags that radiation therapy is curing cancer patients, yet long-term radiation side effects cause many deaths that are not attributed to cancer. (lifeextension.com)
Local radiation works by damaging the DNA in the cancer cells so that the cells die or lose their ability to divide to make more cancer cells, leading to tumor shrinkage. (aimatmelanoma.org)
Proton beam therapy offers a high degree of precision, allowing an escalated radiation dose to be targeted directly on a tumor while sparing the adjacent healthy tissue. (medscape.com)

Surgery is the primary treatment for removal of the brain tumor. (wikipedia.org)
Using different facilities can result in minor variations in the scan which can result in false measurements of the brain tumor. (wikipedia.org)
This is the first report of a home-based virtual-reality visual rehabilitation program for adult patients with hemianopia consecutive to a pediatric brain tumor. (frontiersin.org)
Brain tumor and its treatment can affect the visual system at different levels, from the optic nerves (through compression or infiltration), to subcortical structures like the superior colliculus (SC) and lateral geniculate nuclei (LGN) to optic tracts, optic radiations, and visual cortices ( 1 - 4 ). (frontiersin.org)
Here, we report, for the first time, the feasibility and potential effectiveness of a visual rehabilitation procedure consecutive to a pediatric brain tumor in two young adult patients with hemianopia. (frontiersin.org)

SIOL results from ocular metastasis originating from outside the CNS. (medscape.com)
At the time of treatment, I take a biopsy (tissue sample) that is genetically tested to stratify patients at risk for metastasis. (castleconnolly.com)

Most patients with diseases affecting the pituitary gland require careful ophthalmic follow-up because of the proximity of the visual apparatus. (tuftsmedicalcenter.org)
The result of pituitary disease may be loss of peripheral vision, which may not always be apparent to the patient. (tuftsmedicalcenter.org)
Also, pituitary diseases (especially tumors in this area) can affect the ocular motor nerves causing double vision. (tuftsmedicalcenter.org)
Introduction: Prolactinoma is a type of pituitary tumor that produces excessive amount of the hormone prolactin. (endocrine-abstracts.org)
It is the most common type of hormonally-active pituitary tumor. (endocrine-abstracts.org)

None of this research or treatment application would be possible without a multidisciplinary approach that incorporates the latest in imaging technology to localize tumors, evaluate extent of disease, assess the safety of future microsphere treatment, and confirm treatment success. (diagnosticimaging.com)
Aim: In this study, we aimed to evaluate ABO blood groups and Rh factor in patients with thyroid cancer. (endocrine-abstracts.org)
The study is designed to evaluate the duration of tumor response in each of the two study arms. (news-medical.net)

Our panel discusses what is now a very limited, but growing, experience with the use of these agents to treat ocular inflammatory disease. (ophthalmologytimes.com)
When do you consider using a biologic agent to treat ocular inflammatory disease? (ophthalmologytimes.com)

A cancerous tumor is malignant, meaning it can grow and spread to other parts of the body. (cancer.net)
In some instances, the methods and compositions provided herein can be used to selectively kill cancerous tumor cells without damaging healthy cells. (justia.com)

[ 5 ] and 34-36.4% of all primary brain tumors, making meningiomas the most common primary brain tumors. (medscape.com)
Aim: It is hypotethically thought that increased frequency of breast cancer in patients with primary hyperparathyroidism(PHPT)may be due to the fact that calcium accumulation in the breast may be higher in patients with PHPT giving rise to more breast-related examinations. (endocrine-abstracts.org)
NCT04296890 ), a single-arm trial of 106 patients with FRα-positive, platinum-resistant epithelial ovarian, fallopian tube, or primary peritoneal cancer. (ascopost.com)
Primary brain lymphomas have scant cytoplasm, high grade nuclei and multiple nucleoli, but less pleomorphism than other high grade CNS tumors. (pathologyoutlines.com)

And as our mission statement says, I provide my patients with the highest-quality retina care available - the same kind of care that I would want for my family members and myself. (castleconnolly.com)
The ocular tissue where these tumors arise, the uvea, is a densely pigmented layer that lies for the most part between the sclera and the retina. (medscape.com)

Occular tumour treatment offers huge benefit to patients. (charite.de)
Chemoradiation is the most effective treatment, but its use is associated with significant ocular and cerebral morbidity. (medscape.com)
The prognosis for ocular lymphoma depends on the tumor's histologic type and stage and the treatment employed. (medscape.com)
citation needed] Treatment to remove these tumors always involve radical surgery. (wikipedia.org)
Twenty-two patients (53.7%) underwent topical 5-FU as a sole treatment, and 19 patients (46.3%) as adjuvant and/or debulking therapy. (bmj.com)
Conclusion Topical 5-FU, as a sole or combined therapy, must be considered a long-term safe and effective treatment for patients affected by OSSN. (bmj.com)
With more than 6000 patients treated in the U.S. alone in the past three years, a significant body of peer-reviewed literature has been published to aid in understanding how and in which patient population to use this treatment, particularly yttrium-90 microspheres. (diagnosticimaging.com)
Key issues in 2007 have been refinement of patient selection and expansion of treatment to a variety of histologic tumor types. (diagnosticimaging.com)
PET imaging greatly assists in treatment planning and assessment of response in a large number of different tumor types affecting the liver in patients receiving radioembolization. (diagnosticimaging.com)
When considering surgical treatment, it is important to recognize patients' lifespan, comorbidities, and physical status to assess whether the surgery may be tolerated. (medscape.com)
Histopathology of the tumor may determine the postoperative treatment course for patients. (medscape.com)
In the more compact super-conducting COMET accelerator, proton beams are created since 2007 especially for the treatment of cancer patients in the PROSCAN facility. (psi.ch)
Because we are a strong multidisciplinary team, we are able to work together to create comprehensive and individualized treatment plans for each of our patients. (tuftsmedicalcenter.org)
METHODS The 21 item measure of outcome in ocular disease (MOOD) assesses the patient's view of outcome in terms of visual function and the impact of treatment. (bmj.com)
Patients in the Phase III trial are randomized into one of two treatment arms, including immediate treatment with melphalan via the Delcath PHP System(TM) or treatment with best alternative care. (news-medical.net)
Following guidelines established by U.S. Food and Drug Administration under a Special Protocol Assessment (SPA), patients are permitted to 'cross-over' from the best alternative care arm to receive treatment with the Delcath System at the time of disease progression. (news-medical.net)
Often, treatment involves surgery to remove the eye tumor. (uclahealth.org)
Confirm the presence of FGFR genetic alterations in tumor specimens prior to initiation of treatment with BALVERSA. (nih.gov)
Treatment decisions require careful discussion between members of the healthcare team who are familiar with all aspects of the case, with input from the patient. (aimatmelanoma.org)
However, the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, is now enrolling patients in the Study of Tecovirimat for Human Mpox Virus (STOMP) , which is designed to assess whether tecovirimat is safe and effective for the treatment of mpox in people with the disease. (cdc.gov)
indiscriminate use could promote resistance and render tecovirimat, first line treatment for orthopoxviruses, ineffective for patients. (cdc.gov)
This policy update reflects the most current knowledge regarding which patients will benefit from - and therefore should have access to - this cutting-edge treatment," said ASTRO Chair David C. Beyer, MD. (medscape.com)

These protons penetrate the healthy tissue and only release their energy in the tumour itself. (charite.de)
Future studies comparing high-resolution echographic characteristics to anatomicopathological tissue characteristics will permit a higher degree of tumor characterization, needed to therapeutically address an ocular tumor. (vin.com)
The technique proved to be particularly advantageous in cases with small, medially localized, retrobulbar tumors and in unclear situations when the structure of the lesion resembled surrounding intraorbital tissue. (egms.de)
Surprisingly, conjugation of photosensitive molecules to viral-like nanoparticles does not interfere with the tissue/tumor tropism of the nanoparticles (e.g., the specificity of the viral-like nanoparticles for a particular host tumor tissue or tumor cell). (justia.com)
Chlamydia psittaci is associated with ocular adnexal mucosa-associated lymphoid tissue (MALT) lymphoma, and this association varies across different geographical areas. (medscape.com)

Ocular disease has the greatest morbidity, followed by vascular disease generally from active vasculitis. (medscape.com)

Erosion of the tumor into blood vessels in adjacent tissues, or areas of necrosis within the tumor, can lead to hyphema or vitreous hemorrhage. (medscape.com)
Anti-angiogenic therapy is an old method to fight cancer that aims to abolish the nutrient and oxygen supply to the tumor cells through the decrease of the vascular network and the avoidance of new blood vessels formation. (mdpi.com)
The increased expression of the JAG1 gene may promote the development of new blood vessels that nourish a growing tumor. (medlineplus.gov)

We can also create biologic tear replacement therapies for severe ocular surface disease. (dukehealth.org)
If your corneas are irregularly shaped due to keratoconus, or if you have severe ocular surface disease, we can custom fit you for vision-correcting hard contact lenses , known as scleral contact lenses. (dukehealth.org)
I have only once used infliximab for acute disease, a case of severe acute HLA-B27-associated anterior uveitis in a patient who was traveling and needed a rapid response. (ophthalmologytimes.com)
The degree of muscle weakness involved in MG varies greatly among patients, ranging from a localized form, limited to eye muscles (ocular myasthenia), to a severe or generalized form in which many muscles - sometimes including those that control breathing - are affected. (doctorbhatia.com)
[ 1 , 2 ] MG is sometimes identified as having an ocular and generalized form, although one is not exclusive of the other and the ocular form is considered an initial, milder form of illness that progresses to the more severe generalized form in most but not all patients. (medscape.com)

Whereas Hodgkin lymphoma rarely causes ocular disease, non-Hodgkin lymphoma (NHL) is the most common type of ocular lymphoma. (medscape.com)
The 12-Item Short-Form Health Survey (SF-12) and Ocular Surface Disease Index (OSDI) questionnaires were applied to assess patients ' quality of life and perception of their vision -related functions. (bvsalud.org)
The incidence of VHL disease is approximately one in 40,000 live births and it is estimated that there are approximately 7,000 patients with VHL disease in the United States. (eyecancer.com)
If a patient has a solitary retinal capillary hemangioma, they do not necessarily have VHL disease. (eyecancer.com)
Visual field loss is frequent in patients with brain tumors, worsening their daily life and exacerbating the burden of disease, and no supportive care strategies exist. (frontiersin.org)
[ 4 ] The disease is named after the Turkish dermatologist Hulusi Behçet, who identified it in a patient in 1924 and published a description of the disease in 1937. (medscape.com)
Through discovery that human HSP-60 and HSP-65 share greater than 50% homology with mycobacterial HSP, enhanced T-cell response has been elicited with exposure to both bacterial and human homogenates in Behçet disease patients compared with controls in United Kingdom, Japanese, and Turkish populations. (medscape.com)
Patients received mirvetuximab soravtansine at 6 mg/kg (based on adjusted ideal body weight) as an intravenous infusion every 3 weeks until disease progression or unacceptable toxicity. (ascopost.com)
In the efficacy-evaluable population of patients who had platinum-resistant, measurable disease and received at least one dose of therapy (n = 104), the confirmed overall response rate was 31.7% (95% confidence interval [CI] = 22.9%-41.6%) and median duration of response was 6.9 months (95% CI = 5.6-9.7 months). (ascopost.com)
For patients with uveitis and Behcet's disease, the data for efficacy with infliximab are particularly strong, and this agent should be considered early in disease management. (ophthalmologytimes.com)
ABSTRACT Chagas disease (CD) is a neglected tropical disease associated with poverty in which patients are surrounded by stigma. (scielo.br)
Patients had the dry form of age-related macular degeneration (AMD) or Stargardt disease and received injections of human embryonic stem-cell (hESC)-derived RPE cells. (medscape.com)
Dr Gregori and her multi-institutional team conducted two phase 1/2 trials using hESC-derived RPE cells, one in dry AMD patients (n = 13) and the other in Stargardt disease (n = 13). (medscape.com)
About 25% of patients have bilateral disease, which is always heritable. (msdmanuals.com)
Another 15% of patients have heritable unilateral disease, and the remaining 60% have nonhereditary unilateral disease. (msdmanuals.com)

No differences in survival have been reported for patients treated by these modalities. (bmj.com)

Patients underwent topical chemotherapy with 1% 5-FU four times/day for 4 weeks (one course). (bmj.com)
Some medications, including chemotherapy drugs and drugs that target the immune systems (immunotherapies) have been used in small groups of patients but have not shown clear benefits in improving survival. (aimatmelanoma.org)

The ocular tumor was treated surgically. (diagnosticimaging.com)

Patients with diabetic retinopathy, vitreous hemorrhage, post-surgical uveitis and tumor associated uveitis were excluded. (pakmedinet.com)

Radiologically, these tumors are generally solitary, homogeneously contrast enhancing and usually have no ring enhancement, in contrast to glioblastoma multiforme and metastases. (pathologyoutlines.com)

Retinal capillary hemangiomas are usually orange red, circumscribed, round, vascular tumors supplied by a pair of dilated and tortuous feeder vessels. (eyecancer.com)

Lacrimal gland malignancy was low on the dif-ferential because he was a healthy boy with a normal physical exam and no radiographic characteristics of tumor. (aao.org)

In three Gantries the proton beam rotates around the patient to precisely target the tumour with excellent recovery rates. (psi.ch)
For irradiation of a tumour, the proton beam energy and intensity are varied in order to achieve the desired dose over the tumour volume. (nature.com)

Objective: Current study aimed at finding the differences in etiology of uveitis among male and female genders among patients presenting to the Uveitis Clinic of AFIO, Rawalpindi. (pakmedinet.com)
Methodology: A total of 182 patients diagnosed to have uveitis were recruited through non-probability consecutive sampling. (pakmedinet.com)

The tumors are often small, grow slowly, and rarely spread outside the eye. (cancer.net)

Tumor-induced glaucoma may be produced by obstruction of outflow pathways by pigment cells (pigment dispersion syndrome), melanin-laden macrophages (melanomalytic glaucoma), or tumor cells. (medscape.com)

Childhood tumor is different from but has a wide range varieties in types and presentation due to its origin from different embryogenic layers. (banglajol.info)
Most childhood ocular tumors are benign but there are also life threatening tumors. (banglajol.info)

Tumor extension was 868.7 ± 344.9 pixels (range, 224.6-1481.6 pixels) and were significantly correlated with the preoperative (p=0.011), 30-day postoperative (p=0.017), and 90-day postoperative (p=0.012) SF-12 mental components, as well as the emotional component at the 30th postoperative day (p=0.016). (bvsalud.org)

However, because prognosis depends on multiple factors, such as initial health status, concurrent illnesses, previous vaccination history, and comorbidities, supportive care and pain control may not be enough for some patients (for example, those with weakened immune systems). (cdc.gov)
Context and objective In intensive care units (ICU), clinicians have little information to identify COVID-19 patients at high risk of poor prognosis requiring intubation. (bvsalud.org)

Data including demographic and ocular history were noted. (pakmedinet.com)

[ 16 ] in both immunocompetent patients and immunocompromised patients. (medscape.com)

There is a slight genetic predisposition: particular HLA types seem to predispose for MG (B8 and DR3 with DR1 more specific for ocular myasthenia). (doctorbhatia.com)

This disclosure relates to the field of tumor diagnostics and therapeutics. (justia.com)

Anatomy4

Organisms2

Diseases37

Chemicals and Drugs17

Analytical, Diagnostic and Therapeutic Techniques and Equipment25

Phenomena and Processes10

Disciplines and Occupations1

Information Science1

Health Care9

Melanoma34

Symptoms14

Clinical16

Head and neck tumors2

Corneal6

Visual acuity6

Lesions7

Oncology7

Radiotherapy6

Uveal4

20221

Size of the tumor1

Diagnosis10

Surface squamous neoplasia1

Malignant tumors2

Brachytherapy4

Ophthalmologists2

Solid tumors2

Intraocular tumors3

Intracranial2

Oncologists2

Resection2

Benign tumor2

Treatments5

Conjunctival1

Systemic4

Involvement6

Malignancies2

Radiation10

Brain tumor5

Metastasis2

Pituitary5

Evaluate3

Treat ocular2

Cancerous tumor2

Primary4

Retina2

Treatment22

Tissue5

Morbidity1

Blood vessels3

Severe5

Disease15

Modalities1

Chemotherapy2

Surgically1

Diabetic retinopathy1

Solitary1

Vascular1

Characteristics1

Proton beam2

Uveitis2

Rarely1

Glaucoma1

Childhood2

Postoperative1

Prognosis2

Demographic1

Immunocompetent patients1

Genetic1

Therapeutics1