Estimation of Water Solubility and Octanol/Water Partition Coefficient of Hydrophobic Dyes. (epa.gov)
The important physicochemical properties of three novel bioactive hybrid compounds with different groups (-CH3, -F and -Cl) were studied, including kinetic and thermodynamic solubility in pharmaceutically relevant solvents (buffer solutions and 1-octanol) as well as partition coefficient in system 1-octanol/buffer pH 7.4. (bvsalud.org)
The aqueous solubility of these chemicals is poor and ranged from 0.67 × 10-4 to 1.98 × 10-3 mol·L-1. (bvsalud.org)
The isothermal saturation method was used to determine the drug solubility in seven pharmaceutically relevant solvents within the temperature range from 293.15 to 313.15 K. The IVZ solubility in the studied solvents increased in the following order: buffer pH 7.4, buffer pH 2.0, buffer pH 1.2, hexane, 1-octanol, 1-propanol, ethanol. (bvsalud.org)
Depending on the solvent chemical nature, the compound solubility varied from 6.7 × 10-6 to 0.3 mol·L-1. (bvsalud.org)
Aqueous1
Good dispersion, 1% aqueous liquid is milky, white liquid. (actionext.com)
Alcohol3
Here, we recorded T-currents and underlying low-threshold calcium spikes from neurons of nucleus reticularis thalami (nRT) in brain slices from young rats and investigated the mechanisms of their modulation by an anesthetic alcohol, 1-octanol. (aspetjournals.org)
About Sec-Octyl alcohol ethoxylates;2-Octanol ethoxylates: Good dispersion, 1% solution in water is a white milky liquid. (actionext.com)
A fatty alcohol that is 3-octanol substituted by methyl groups at positions 3 and 7. (chemspider.com)
Octan-1-ol1
1-Octanol, also known as octan-1-ol, is the organic compound with the molecular formula CH3(CH2)7OH. (wikipedia.org)
Buffer pH2
The temperature dependencies of partition coefficients of new hybrids in the model system 1-octanol/buffer pH 7.4 as a surrogate lipophilicity were measured by the shake flask method. (bvsalud.org)
Temperature dependences of the compound partition coefficients were obtained in a binary 1-octanol/buffer pH 7.4 system and the transfer thermodynamic functions were calculated. (bvsalud.org)
Compound2
The distribution of a compound between water and octanol is used to calculate the partition coefficient, P, of that molecule (often expressed as its logarithm to the base 10, log P). Water/octanol partitioning is a relatively good approximation of the partitioning between the cytosol and lipid membranes of living systems. (wikipedia.org)
A temperature dependence of saturated vapor pressure of isavuconazole (IVZ), an antimycotic drug, was found by using the method of inert gas-carrier transfer and the thermodynamic functions of sublimation were calculated at a temperature of 298.15 K. The value of the compound standard molar enthalpy of sublimation was found to be 138.1 ± 0.5 kJ·mol-1. (bvsalud.org)
Octyl2
Esters of octanol, such as octyl acetate, occur as components of essential oils. (wikipedia.org)
Extractant 1 showed very fast extraction kinetics and a high extraction capacity as compared to those of the commercial extractant di- n -octyl sulfide. (nature.com)
Sulfate1
Sodium n - Octanol Sulfate is easily dispersible in water. (tatayoung.com)
Ethylene2
Octanol is mainly produced industrially by the oligomerization of ethylene using triethylaluminium followed by oxidation of the alkylaluminium products. (wikipedia.org)
The objects of investigation are monohydric alcohols n-pentanol (CH2)4CH3-OH and n-octanol (CH2)7CH3-OH. (kiev.ua)
Synthesis1
1-Octanol is manufactured for the synthesis of esters for use in perfumes and flavorings. (wikipedia.org)
Methyl2
In contrast, 12-(2-cyanoethyl)-6,7,12,13-tetrahydro-13-methyl-5-oxo-5 H -indolo(2,3- a )pyrrolo(3,4- c )-carbazole (Go 6976), an inhibitor of calcium-dependent PKC, decreased baseline T-current amplitude in nRT cells and abolished the effects of subsequently applied 1-octanol. (aspetjournals.org)
Pursuant to section 74 of the Canadian Environmental Protection Act, 1999 (CEPA 1999), the Ministers of the Environment and of Health have conducted a screening assessment on benzene, 1-methyl-2-nitro- (2-nitrotoluene), Chemical Abstracts Service Registry Number 88-72-2. (gc.ca)
Degradation1
Furthermore, the preferential localization of theaflavin 3-gallate in the octanol phase prevented (-)-epicatechin-quinone-induced degradation. (elsevierpure.com)
Partition4
The octanol/water and octanol/air partition coefficients are predicted for a group of polar solvents using density functional theory (DFT) calculations in combination with a solvation model based on density (SMD) and are in excellent agreement with experimental data. (simulations-plus.com)
for the octanol/air partition coefficient, the M06-2X functional yielded the best performance. (simulations-plus.com)
To the best of our knowledge, this is the first computational approach for the prediction of octanol/air partition coefficients by DFT calculations, which has remarkable accuracy and precision. (simulations-plus.com)
Chemicals having log octanol/water partition coefficients between 1 and 2 are well absorbed. (cdc.gov)
Ethane1
The effects of 1-octanol were also abolished by chelation of intracellular calcium ions with 1,2-bis(2-aminophenoxy)ethane- N , N , N ′, N ′-tetraacetic acid. (aspetjournals.org)
Reaction1
In the present study, we found that a 1-octanol/buffer biphasic system improved the yield of theaflavin 3-gallate in a tyrosinase-catalyzed synthetic reaction with (-)-epicatechin and (-)-epigallocatechin gallate. (elsevierpure.com)
Boiling1
The Pd(II) extraction abilities of 1 and 2 were studied in high-boiling-point and environmentally friendly hydrocarbon diluents. (nature.com)
Chemicals1
Animals continuously encounter heterogenous mixtures of chemicals that fluctuate in their concentrations and temporal properties, and provide information about the presence and location of food, mates, competitors, and predators [ 1 , 2 ]. (plos.org)
Melting1
The IVZ thermophysical properties-melting point and enthalpy-equaled 302.7 K and 29.9 kJ mol-1, respectively. (bvsalud.org)
Density2
Density, Viscosity, and Speed of Sound of (1-Octanol + 2-Methoxyethanol),(1-Octanol + N,N-Dimethylacetamide), and (1-Octanol + Acetophenone) at Temperatures of (298.15, 308.15, and 318.15) K". Journal of Chemical & Engineering Data. (wikipedia.org)
JUXTAPID is a microsomal triglyceride transfer protein inhibitor indicated as an adjunct to a low-fat diet and other lipid-lowering treatments, including LDL apheresis where available, to reduce low-density lipoprotein cholesterol (LDL-C), total cholesterol (TC), apolipoprotein B (apo B), and non-high-density lipoprotein cholesterol (non-HDL-C) in patients with homozygous familial hypercholesterolemia (HoFH) ( 1 ). (drugs.com)
Found1
We found that 1-octanol inhibited native T-currents at subanesthetic concentrations with an IC 50 of approximately 4 μM. (aspetjournals.org)
Https1
Numerical data for all behavioral and calcium imaging experiments shown in Figs 1 - 4 and S1 - S5 are provided in https://doi.org/10.5281/zenodo.6537728 . (plos.org)
Phase1
However, self-dimerization was suppressed in the octanol phase, allowing oxidized (-)-epigallocatechin gallate to participate in coupling with (-)-epicatechin quinone, leading to effective production of theaflavin 3-gallate. (elsevierpure.com)
Calcium1
Taken together, these results suggest that inhibition of calcium-dependent PKC signaling is a possible molecular substrate for modulation of T-channels in nRT neurons by 1-octanol. (aspetjournals.org)
20231
2023. The atmospheric fate of 1,2-Dibromo-1 4-(1,2-dibromoethyl)cyclohexane (TBECH): Spatial patterns, seasonal variability, and deposition to Canadian coastal regions . (sfu.ca)
Acid1
Extractant 1 exhibited very selective Pd(II) extraction and high acid stability, demonstrating its industrial applicability for the extraction of Pd(II) from leached automotive catalyst liquors containing PGMs and base metals. (nature.com)
Substance1
2-Octanol Record in the GESTIS Substance Database of the Institute for Occupational Safety and Health Bhattacharjee, A. (wikipedia.org)
Higher1
To explore the mechanisms underlying higher 1-octanol potency in inhibiting native nRT T-currents, we tested the effect of the protein kinase C (PKC) activator phorbol 12-myristate 13-acetate (PMA) and PKC inhibitors. (aspetjournals.org)
Price1
Our business has strived to establish a really efficient and stable personnel team and explored an effective high quality manage process for cas 111 87 5 1 octanol with low price make sure you mail your needs with a detailed list including the style/item and quantity you require. (azgshenyu.com)
System1
Natural killer cells are cytolytic lymphocytes belonging to the innate immune system and are involved in anti-viral and anti-tumor responses ( 1 ) and are recognized as major players in immune-mediated anti-tumor therapies ( 2 ). (frontiersin.org)
Point1
With a flash point of 81 °C, 1-octanol is not seriously flammable, though its autoignition temperature is as low as 245 °C. 1-Octanol is mainly consumed as a precursor to perfumes. (wikipedia.org)
Route1
The Kuraray process defines an alternative route to 1-octanol, but using C4 + C4 building strategy. (wikipedia.org)
Mechanism1
The Pd(II) extraction mechanism of 1 was studied using FT-IR spectroscopy. (nature.com)
Essential1
In our scientific activity at the Division of Physical Chemistry 1 we find it essential to establish long-term goals and policies that are based on an unbiased analysis of the specific situation, rather than an uncritical following of the current trends. (lu.se)