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  • Pou5f1
  • Examples include: Oct-1 - POU2F1 Oct-2 - POU2F2 Oct-3/4 - POU5F1 Oct-6 - POU3F1 Oct-7 - POU3F2 Oct-8 - POU3F3 Oct-9 - POU3F4 Oct-11 - POU3F4 Petryniak B, Staudt LM, Postema CE, McCormack WT, Thompson CB (1990). (wikipedia.org)
  • pluripotent factors
  • Because the loss of mouse Brd4 has a peri-implantation phenotype (at the time random XCI takes place in the epiblast) and given the tight linkage between XCI and differentiation, we questioned whether BRD4 might interact with pluripotent factors. (nih.gov)
  • nucleosome
  • Nucleosome Remodeling Factor (NURF) is an ATP-dependent chromatin remodeling complex first discovered in Drosophila melanogaster (fruit fly) that catalyzes nucleosome sliding in order to regulate gene transcription. (wikipedia.org)
  • Nanog
  • This effect has also been seen with the Thomson reprogramming factors, reverting human fibroblast cells to iPSCs through Oct-4, along with Sox2, Nanog, and Lin28. (wikipedia.org)
  • Nanog regulates the transcription of Rex1 through 2 strong transactivation domains on the C-terminus which are required to activate the Rex1 promoter. (wikipedia.org)
  • polymerase
  • 1. Dignam, J. D., Lebovitz, R. M., and Roeder, R. G. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. (wikipedia.org)
  • Chromosome
  • The GYG1 gene is located on the long arm of the chromosome 3, between positions 24 and 25, from base pair 148,709,194 to base pair 148,745,455. (wikipedia.org)
  • Cells
  • Composed of the purified RNA polymerases and components extracted from cell nuclei, the systems allow researchers to recreate transcription in a test tube in a way that faithfully mimics the real process in cells. (wikipedia.org)
  • BRN3A (POU4F1) is a class IV POU domain-containing transcription factor highly expressed in the developing peripheral sensory nervous system (dorsal root ganglia, trigeminal ganglion, and hindbrain sensory ganglia), certain regions of the central nervous system, retinal neurons called ganglion cells, and in cells of the B- and T-lymphocytic lineages. (wikipedia.org)