Occur gene expression. Medical search. Frequent questions

Differential gene expression analysis revealed that the extent of differentiation between species and the set of differentially expressed genes varied across tissues. (hal.science)
Because of the recent development of new methods (especially microarrays) for identifying differentially expressed genes, a burst of research on caste differentiation is predicted. (europa.eu)
We have investigated potential mechanisms of regulation of rotavirus gene expression by functional evaluation of two differentially expressed viral mRNAs. (microbiologyresearch.org)
These differentially expressed genes are primarily involved in electron transport, the TCA cycle, and ATP synthesis. (usda.gov)
Differentially expressed genes also included ribosomal proteins (85 of 109) as well as mitochondrial ribosomal proteins (40 of 77), suggesting an increase of translational capacity. (usda.gov)
The peroxisome proliferator- activated receptor gamma coactivator 1-alpha ( Ppargc1a ) gene was found to be involved in the networks generated using Ingenuity Pathway Studio (IPA) from the differentially expressed transcript cluster lists of week 2 versus 1, week 3 versus 2, week 6 versus 3, and week 8 versus 6. (molvis.org)

In contrast to the early expression of CD44 in small adenomas, mutations of K-ras and p53 were detected preferentially in large adenomas and late-stage adenomas containing carcinoma. (johnshopkins.edu)
Hyperferritinemia-cataract syndrome is caused by mutations in the FTL gene. (medlineplus.gov)
The mutations that cause hyperferritinemia-cataract syndrome are found in a segment of the gene called the iron responsive element (IRE). (medlineplus.gov)
Mutations in the IRE segment of the FTL gene prevent it from binding with IRP, interfering with the mechanism by which ferritin production is matched to iron levels and resulting in excess ferritin being formed. (medlineplus.gov)
Mutations in the gene for cardiac myosin-binding protein C account for approximately 15 percent of cases of familial hypertrophic cardiomyopathy. (nih.gov)
The spectrum of disease-causing mutations and the associated clinical features of these gene defects are unknown. (nih.gov)
The genotypes of these family members were determined, and the clinical status of 212 family members with mutations in the gene for cardiac myosin-binding protein C was assessed. (nih.gov)
eight defects (insertions, deletions, and splice mutations) were predicted to truncate cardiac myosin-binding protein C. The clinical expression of either missense or truncation mutations was similar to that observed for other genetic causes of hypertrophic cardiomyopathy, but the age at onset of the disease differed markedly. (nih.gov)
Survival was generally better than that observed among patients with hypertrophic cardiomyopathy caused by other mutations in the genes for sarcomere proteins. (nih.gov)
The clinical expression of mutations in the gene for cardiac myosin-binding protein C is often delayed until middle age or old age. (nih.gov)
Delayed expression of cardiac hypertrophy and a favorable clinical course may hinder recognition of the heritable nature of mutations in the cardiac myosin-binding protein C gene. (nih.gov)
Mutations in the human gene that encodes Tbx5 result in congenital heart disease and, in particular, defects in the ventricular septum, the muscular wall that separates the ventricle into two sections. (sciencedaily.com)
SCID results from mutations in any of more than 15 known genes. (medscape.com)
Scope includes mutations and abnormal protein expression. (cancerindex.org)
In the remaining cases, the genetic basis is not well-understood, but in tissue from some patients, other mutations in the same gene are involved. (msdmanuals.com)
During our lifetime, spontaneous mutations can occur in the cells. (lu.se)
Mattias Höglund and his staff have drawn up a classification system for bladder cancer based on information on genetic mutations and changes in gene expression in both the genome and the epigenome. (lu.se)

1%) of genes are imprinted, meaning that gene expression occurs from only one allele (some recent studies have questioned this assertion, claiming that the number of regions of parent-of-origin methylation in, for example, the human genome, is much larger than previously thought). (stackexchange.com)
The frequent expression of CD44 prior to K-ras and p53 gene alterations in colorectal neoplasia suggests that activation of CD44 gene expression is related to earlier events in the adenoma-carcinoma sequence, possibly cell activation and proliferation following APC gene mutation or alteration of DNA methylation. (johnshopkins.edu)
These small siRNAs act as guides to where methylation will occur, silencing gene expression. (sciencedaily.com)
To explore the effect of DNA methyltransferase, demethylase and methyl-CpG binding protein MeCP2 on the expressions and methylation of hMSH2 and proto-oncogene in human gastric cancer. (wjgnet.com)
Promoter methylation of p16 INK4A , c-myc and hMSH2 genes was assayed by methylation-specific PCR (MSP) and sequencing (mapping). (wjgnet.com)
Methylation occurs a billion times a second throughout the body, affecting everything from fetal development to brain function. (healthyplace.com)
Just over 30 years ago, researchers discovered that there was a connection between DNA methylation and gene expression. (lu.se)

The proteins are produced under instruction from genes. (edu.au)
Switching different genes on or off affects which particular proteins are produced. (edu.au)
Gene expression in living cells is strictly self-regulated to ensure that the correct amounts of proteins are made at the most appropriate timing and location for maintaining cellular homeostasis. (nature.com)
ELISA for 3 proteins (HSPA6, CCL21 and EPB42) with gene expression fold changes of 5.1, 2.94 and 4.4 at 48 hours showed protein content changes of 88.01%, 42.19% and -37.17% at 48 hours, respectively. (usda.gov)
miRNAs regulate proteins expressions by arresting or degrading the mRNAs. (cancerindex.org)
Using an RNA FISH-Flow HIV-1 reactivation assay, we demonstrate that SLFN12 expression is enriched in infected cells positive for HIV-1 transcripts but negative for HIV-1 proteins. (bvsalud.org)
Our results uncover a crosstalk between the three major stages of gene expression coordinated by Xrn1 to maintain appropriate levels of membrane proteins. (bvsalud.org)
To occur the adhesion of CAMs to the biomaterial, it is necessary their interaction with some components of extracellular matrix, such as proteoglycans, collagen and proteins 23 . (bvsalud.org)

The objectives of this study were to determine changes in gene expression within the postmortem interval and relate these affected genes and pathways to QTL for pork quality. (usda.gov)
The aim of this study was to identify the genes and pathways underlying the growth of the mouse sclera during postnatal development. (molvis.org)
What pathways are this gene/protein implicaed in? (cancerindex.org)
they can combine with the promoter regions of key genes in signaling pathways to regulate their transcription levels and, in turn, plant resistance to stress. (biomedcentral.com)

In this study we examined the relationship of CD44 expression to somatic genetic events in the adenoma-carcinoma sequence: point mutation of K-ras in codons 12 and 13 and overexpression of p53 protein as a marker of gene mutation. (johnshopkins.edu)
For ASP0312-Sp, the sequence corresponding to the downstream region of nsik up to the 5′ terminus of the gene encoding the cell wall binding repeat protein in osk_001 was replaced by a fragment of ≈30 kb from pneumococcus. (cdc.gov)
Tau ist ein neuronales Protein, das sowohl im Zytoplasma, wo es Mikrotubuli bindet, als auch im Kern, wo es unkonventionelle Funktionen wie die Modulation von Alzheimer-Gene ausübt. (jove.com)
This gene provides instructions for making the ferritin light chain, which is one part (subunit) of the protein ferritin . (medlineplus.gov)
We measured the levels of gene 5 and gene 6 mRNA and showed that they were not significantly different, and protein analysis indicated no difference in stability of NSP1 compared with VP6. (microbiologyresearch.org)
Nucleotide sequence and expression in Escherichia coli of the gene encoding the nonstructural protein NCVP2 of bovine rotavirus. (microbiologyresearch.org)
Cloning and nucleotide sequence of the simian rotavirus gene 6 that codes for the major inner capsid protein. (microbiologyresearch.org)
On the other hand, mechanisms that impair the circadian clock genes, such as circadian locomotor output cycles kaput ( CLOCK ), brain and muscle Arnt-like protein 1 ( BMAL1 ), and period genes ( PER1 , PER2 , and PER3 ), contribute to defective beta-cell function and development of type 2 diabetes [ 7 - 12 ]. (hindawi.com)
The expression level from luc 25.7k is 1000-times higher than that with luc 1.7k, indicating that the protein yield per target gene is increased by 1000-times of magnitude for a longer template, luc 25.7k (Fig. 1 d). (nature.com)
These results imply that gene expression and protein translation continue to occur in postmortem muscle and could impact meat quality. (usda.gov)
The research shows how a specific protein that turns on genes is involved in heart formation in turtles, lizards and humans. (sciencedaily.com)
Tbx5 is a transcription factor, a protein that turns other genes on or off. (sciencedaily.com)
The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. (cancerindex.org)
What does this gene/protein do? (cancerindex.org)

To gain insight into the molecular mechanisms and determinants of gene expression evolution in natural populations, we analyzed the transcriptome from multiple tissues of two recently diverged Ficedula flycatcher species and their naturally occurring F 1 hybrids. (hal.science)
Nickel is a naturally occurring element in water, soil, air, and living organisms, and is essential to microorganisms and plants. (mdpi.com)
Elemental lead is a soft, malleable, dense, blue-gray metal that occurs naturally in soils and rocks. (cdc.gov)
Federal law permits the unregulated sale of naturally occurring substances as long as marketers avoid therapeutic claims. (healthyplace.com)

In general, mRNA levels of ECM and collagen genes have been found to be downregulated in both the adult mouse sclera [ 6 ] and cornea [ 7 ] when compared with samples from an earlier developmental stage. (molvis.org)
We identified a large number of genes whose mRNA levels are modulated during differentiation of MPRO cells. (yale.edu)

For the vast majority of autosomal genes, expression occurs from both alleles simultaneously. (stackexchange.com)
Common to all tissues, a higher proportion of Z-linked genes than autosomal genes showed differential expression, providing evidence for a fast-Z effect. (hal.science)
Autosomal Dominant Genetic disorders determined by a single gene (Mendelian disorders) are easiest to analyze and the most well understood. (msdmanuals.com)

Instead, we found evidence that cis -regulatory changes play a significant role in the evolution of gene expression in testis, which illustrates the tissue-specific nature of cis -regulatory evolution bypassing constraints associated with pleiotropic effects of genes. (hal.science)
These data define a regulatory mechanism for the difference in amounts of VP6 and NSP1 and provide evidence for post-transcriptional control of rotavirus gene expression mediated by the translational efficiency of individual viral mRNAs. (microbiologyresearch.org)
one includes structural genes encoding enzymes that directly participate in the formation of anthocyanins and other flavonoids, and the other comprises regulatory genes controlling the transcription of structural genes. (scirp.org)
A case study of homologues of the shoot meristem identity gene TFL1 reveals differences in cis-regulatory elements that could explain this divergence. (jic.ac.uk)
Such differences in the expression dynamics of duplicated genes highlight the challenges involved in translating gene regulatory networks from diploid model systems to more complex polyploid crop species. (jic.ac.uk)
During evolution, new genetic regulatory elements evolved to tell the Tbx5 gene to form a sharp boundary of Tbx5 expression. (sciencedaily.com)
Important regulatory factors, TFs bind to the promoter regions of target genes and activate or inhibit their transcription. (biomedcentral.com)

Gene regulation can occur at any point in gene expression, from the start of the transcription phase to the translation phase. (nature.com)
Due to the complexity of gene regulation, unveiling the complete mechanism of gene regulation has been a long-standing quest. (nature.com)
To elucidate the complex mechanism of gene regulation in living cellular systems, it is necessary to closely investigate each phase of gene expression and also to shed light on the cooperative effects between transcription and translation. (nature.com)
The aforementioned complex factors have made it difficult to investigate the impact of the DNA length on gene regulation, which has been an unexplored topic. (nature.com)
SCIENCE TRANSLATIONAL MEDICINE Scientists at Massachusetts General Hospital and Harvard Medical School have-for the first time-imaged epigenetic regulation of gene expression in the living human brain. (the-scientist.com)
The up-regulation of proto-oncogene may be the consequence of epigenetic control of gene expression by demethylase, and mbd2 is involved in the regulation of hMSH2 expression in human gastric cancer. (wjgnet.com)
Changes in expression with maze task occurred in 789 genes: up-regulation in 96 genes and down-regulation in 208 genes. (umich.edu)
Claimed to be the premier team to actually exhibit a mechanical effect that could be at play in this process, these findings could hold new meaning to understanding gene regulation. (healthjockey.com)
There's more to gene regulation than biochemistry. (healthjockey.com)
Seen as a common mechanism for gene regulation, it may also occur in complex organisms including humans. (healthjockey.com)

The human genome encodes 54 functional keratin genes , located in two clusters on chromosomes 12 and 17. (wikipedia.org)
Also known as "jumping genes" for their ability to be expressed and then re-insert themselves at random into a different area of the genome, transposons are dangerous because they can cause damage to DNA and disrupt genetic function. (sciencedaily.com)
We show that flowering time genes are preferentially retained relative to other genes in the OSR genome. (jic.ac.uk)
To understand the molecular-genetic basis of functional specialization and identify potential drug targets specific to each neuron subtype, we performed a genome wide assessment of both gene expression and splicing across EXC, PV, SST and VIP neurons from male and female mouse brains. (jneurosci.org)
We used a genome-wide analysis which not only examined differential gene expression levels but could also detect differences in splice isoform usage. (jneurosci.org)
Genome-wide identification and expression analysis of the bZIP transcription factor family genes in response to abiotic stress in Nicotiana tabacum L. (biomedcentral.com)

Most gene expression studies for identification of meat quality candidate genes involve tissues collected at death, though studies have reported many genes to be upregulated postmortem (thanatotranscriptome). (usda.gov)
We picked up 12 candidate genes in conjunction with the memory. (umich.edu)

Contrary to Horton's representation of our motives for doing this work, we, in fact, accidentally stumbled onto this rather startling find while carrying out experiments designed to understand the role certain genes play in Drosophila brain development. (nybooks.com)
Bipolar disorder, ASD, and schizophrenia all seem to activate certain genes in astrocytes, which are star-shaped brain cells that perform many essential functions in the central nervous system. (medicalnewstoday.com)

Therefore, caste differentiation must involve the differential expression of genes that are shared by all castes. (europa.eu)

Gene-expression tests like this, that analyze a small number of genes at a time, are widely available for breast, prostate and some other cancers, and they've proven to be a very accurate and inexpensive alternative to other types of tests," said Chen. (ucsf.edu)
We used an oligonucleotide chip containing 13,179 probe sets corresponding to about 7000 murine genes to analyze patterns of mRNA expression in the same RNA samples used for DD. (yale.edu)
Using ribosome footprinting, we analyze translational changes that occur upon CHIKV infection. (bvsalud.org)

Neoplastic progression of colorectal epithelial cells from benign adenomas to malignant carcinomas appears to result from a series of genetic alterations involving both oncogenes and tumor suppressor genes. (johnshopkins.edu)
Can Gene Expression Predict if a Brain Tumor Is Likely to Grow Back? (ucsf.edu)
Using samples from 1,856 meningioma patients at 12 medical centers in the U.S., Europe and Hong Kong, Raleigh's team came up with a set of 34 genes whose gene expression patterns had the potential to predict whether a tumor would return. (ucsf.edu)
In 15% of cases, this type is familial and related to a germline mutation in the SMARCB1 gene, a tumor suppressor gene located at 22q11.23, very close to the NF2 gene. (msdmanuals.com)

Furthermore, mRNA expression of circadian clock genes is dampened in peripheral leucocytes of subjects with poor sleep quality. (hindawi.com)
2001), with overt encephalopathy, seizures, and peripheral neuropathy generally occurring at much higher levels (e.g., higher than 100-200 µg/dL). (cdc.gov)

The aims of this research work were to determine the patterns of antibiotic resistance in Escherichia coli isolates from the meat of wild or domestically reared pigeons from Spain, to detect the presence of virulence and antibiotic resistance genes, and to carry out a phylogenetic classification of the isolates. (mdpi.com)
Antibiotic resistance gene distribution in Community and Hospital Isolates of Bacteroides spp. (cdc.gov)

However, while testis showed the highest divergence of gene expression among tissues, it showed no clear signature of misexpression in F 1 hybrids, even though these hybrids were found to be sterile. (hal.science)
Using a transcriptome time series in two tissues (leaf and shoot apex) across development we show that 67% of these retained flowering time genes are expressed. (jic.ac.uk)
The transcriptional levels of p16 INK4A and MeCP2 genes did not display any difference between gastric cancerous and matched non-cancerous tissues. (wjgnet.com)
Likely other tissues, many events occur when a given biomaterial is in contact with the biological bone environment, with molecular and cellular interactions influencing on the tissue features surrounding the biomaterial. (bvsalud.org)

It is remarkable that white is one of the most studied genes in man's quest to understand genetic control and function in Drosophila (described in 1910 by Thomas Hunt Morgan as the first example of sex-linked inheritance in flies) and yet this phenomenon had not previously been reported. (nybooks.com)
ASD and bipolar disorder do appear to share specific genetic expression patterns in the brain. (medicalnewstoday.com)
Thus modern developmental biology views development as the expression of a preformed genetic program which controls the epigenetic development of an undifferentiated egg into a morphologically complex adult. (encyclopedia.com)
With the advances in BMT and gene therapy, patients now have a better likelihood of developing a functional immune system in a previously lethal genetic disease. (medscape.com)
These effects are attributed not only to genetic changes but to epi genetic changes (ie, post-DNA modifications that occur throughout the lifespan) that modulate gene expression. (medscape.com)

The molecular steps in the replication pathway that regulate the levels of viral gene expression are not well defined. (microbiologyresearch.org)

Exon 8 of the mouse α 6 subunit gene was disrupted by homologous recombination. (jneurosci.org)

DAVID was used to perform the Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway analysis for the different expression genes (DEGs). (medscimonit.com)

Its inhibition maintains the opening of those genes and promotes their transformation into long-lived memory CAR-Ts. (unige.ch)
Here we demonstrate that similar activity amplification occurs in mice, and that this is related to suppressed inhibition to PB neurons from the central nucleus of the amygdala (CeA) in animals of either sex. (iasp-pain.org)

Therefore, during development female cells apply epigenetic changes to permanently close down all the genes on one X chromosome. (edu.au)
Our researchers are using X-inactivation as a model of epigenetic changes, to discover new ways that genes are switched on and off. (edu.au)
The body responds to the environment in which we live and epigenetic changes occur. (lu.se)
What was also discovered was that the body also responds to the environment in which we live - epigenetic changes occur as a result of environmental and lifestyle factors that affect us over a long period of time. (lu.se)

By epigenetics we mean permanent changes to gene expression that are not caused by changes in the DNA sequence", says Mattias Höglund, Professor of Oncology at Lund University. (lu.se)

As scientific tools for probing genes become increasingly powerful, research into human differences has exploded. (gnxp.com)
These results reveal numerous examples where neuron subtype-specific gene expression, as well as splice-isoform usage, can explain functional differences between neuron subtypes, including in presynaptic plasticity, postsynaptic receptor function, and synaptic connectivity specification. (jneurosci.org)
In another example, the researchers found that only one out of the four types of immune cells detected showed major differences in gene expression. (newswise.com)

It was suggested that Tgfβ1 could possibly act as a signaling molecule in controlling collagen gene expression and modulate ECM during ocular growth. (molvis.org)

The work also has important implications for the understanding of congenital heart defects, which are the most common human birth defect, occurring in one out of every one hundred births worldwide. (sciencedaily.com)

Multiple carboxylase deficiency (MCD) is one of many metabolic disorders that occur in the absence of the coenzyme activity of biotin. (medscape.com)
Biotin is also important for cell signaling, gene expression, and chromatin structure. (medscape.com)
More than 2000 human genes depend on biotin for expression. (medscape.com)
The resulting cDNA was fragmented, labeled with biotin, and hybridized to a Mouse Gene 1.0 ST Array. (molvis.org)

Identifying caste-specific patterns of gene expression thus offers a special opportunity to study the generation of adaptive morphological variation by a fundamental biological process, and is the key to profound understanding of the evolution of sociality. (europa.eu)
Now, researchers at UC San Francisco and Northwestern Medicine, in collaboration with 10 other medical centers, have found a highly accurate way to predict the best treatment for patients based on patterns of gene expression - which genes are turned on and off - in their tumors. (ucsf.edu)

These dispersed bacteria have distinct phenotypic properties different from those of both biofilm and broth-grown, planktonic bacteria, with the dispersed population showing differential virulence gene expression characteristics resulting in a significantly increased ability to disseminate and cause infection of otherwise sterile sites, such as the middle ear, lungs, and bloodstream. (lu.se)
In this study, we determined that changes in the nasopharyngeal environment result in the release of bacteria from colonizing biofilms with a gene expression and virulence phenotype different not only from that of colonizing biofilm bacteria but also from that of the broth-grown planktonic bacteria commonly used for pathogenesis studies. (lu.se)

In order to identify the memory-related gene expression by behavioral test, we performed DNA microarray analysis to investigate the changes in gene expression in the hippocampus. (umich.edu)

Additional mechanisms include generating reactive oxygen species and altering gene expression (ATSDR, 2007). (cdc.gov)
Approximately 1200 RNA species were clustered in various patterns of expression. (cdc.gov)
Further clustering highlighted >400 species with increased expression after treatment in one or more of the cell strains, including metabolic enzymes and transcription factors. (cdc.gov)
A team of international scientists, including researchers from the Milner Centre for Evolution at the University of Bath, have discovered that evolution has used a kind of universal formula for turning non-monogamous species into monogamous species - turning up the activity of some genes and turning down others in the brain. (bath.ac.uk)
The researchers compared gene expression in male brains of all 10 species to determine what changes occurred in each of the evolutionary transitions linked to the closely related animals. (bath.ac.uk)
Arranging genes from distantly related species - such as a fish and a mammal - into groups based on sequence similarities, the team was able to identify a common evolutionary formula that led to pair bonds and co-parenting in the five species that behave monogamously. (bath.ac.uk)
We further studied the collinearity between these genes and related genes of six other species. (biomedcentral.com)

This normally occurs when iron levels are low, because under those circumstances less ferritin is needed to store the iron. (medlineplus.gov)
Transcript levels of circadian clock genes ( BMAL1 , PER1 , PER2 , and PER3 ) were determined by real-time quantitative polymerase chain reaction. (hindawi.com)
These changes in RNA levels are known as changes in "gene expression. (newswise.com)
interacting genes at different noise levels or temperatures. (lu.se)

It regulates the expression of genes. (healthyplace.com)
Ample evidence indicates that codon usage bias regulates gene expression. (bvsalud.org)
The highly conserved 5'-3' exonuclease Xrn1 regulates gene expression in eukaryotes by coupling nuclear DNA transcription to cytosolic mRNA decay. (bvsalud.org)

This process is mediated by various enzymes modifying chromatin structures to achieve the diversity of epigenetic space and the intricacy in gene expression files. (frontiersin.org)

The stx1 gene abundance was only detected in tissue samples collected in year 2 and did not differ among breeds. (frontiersin.org)
Expression of stx2 was detected in 13 RAJ tissue samples (2014: n=6, 2015: n=7), while expression of stx1 was not detected. (frontiersin.org)
The average mRNA level of Dnmt1 gene from cancerous tissue was higher and that of mbd2 gene from cancerous tissue was lower than that from non-cancerous tissue, respectively. (wjgnet.com)

Data Mining Tool software (Affymetrix, Santa Clara, CA) was used to separate genes in clusters based on their expression patterns over time. (cdc.gov)

This suggests that they originated from a series of gene duplications on these chromosomes. (wikipedia.org)
Additionally, the identified relationship between expressions of host immune genes and stx2 suggests that the host animal may regulate stx2 expression in colonizing STEC through immune functions. (frontiersin.org)
The finding suggests a level of order in how complex social behaviours come about through the way that genes are expressed in the brain. (bath.ac.uk)

Consequently, various anomalous clinical and laboratory findings occur. (medscape.com)
Although the function of these genes varied, these findings provide insight into the effects of OTQ, and emphasize the role of inter-individual variation in gene expression profiles. (cdc.gov)
We discuss a possible mechanism for the observed unusual interruption of sexual behavior of the gynandromorph by reference to the fru expression pattern and our recent findings on the sexually dimorphic response to female-derived pheromones. (springer.com)

6 ], the transforming growth factor beta 1 ( Tgfβ1 ) gene and several collagen genes were significantly downregulated in 8-week-old B6 mice scleras when compared with 3-week-old B6 mice scleras. (molvis.org)

Disruption of these clock genes affects locomotor activity, feeding behavior, metabolism, and glucose homeostasis [ 14 ]. (hindawi.com)
For example, the fat mass and obesity-associated (FTO) gene polymorphism affects the susceptibility to obesity but accounts for less than 0.5% of the overall variance in body mass index (BMI). (medscape.com)

The team added their newest data on noise-induced hearing loss to gEAR - Gene Expression Analysis Resource - a tool developed by her laboratory that allows researchers not trained in informatics to browse gene expression data ( published earlier this summer ). (newswise.com)
After making their study known to other researchers in their field, the team heard from scientists at Decibel Therapeutics (led by Joe Burns, PhD) and the Karolinska Institute (led by Barbara Canlon, PhD), who had the gene expression data from the inner ear's neurons, side wall and immune cells from before and after noise damage. (newswise.com)
The researchers seem to have observed that tension on DNA molecules could influence the expression of genes. (healthjockey.com)

We propose an underlying mechanism for the favorable effect of longer DNA on gene expression in terms of the enhancement of access of RNA polymerase to the shrunken conformation. (nature.com)
It is expected that the enhancement of gene expression efficiency with a shrunken DNA conformation would also be a rather general mechanism in living cellular environments. (nature.com)
However, as potentially carcinogenic exposures have already occurred, its mechanism of action is of interest. (cdc.gov)
To further understand the mechanism of action of OTQ, gene expression was studied in four strains of primary normal human mammary epithelial cells. (cdc.gov)
As a result, scientists have been working to understand the mechanism behind how the damage to hearing actually occurs. (newswise.com)
Afterwards, the specific mechanism of miR-543 and Smad7 in PA were determined with the use of ectopic expression, depletion and reporter assay experiments. (cancerindex.org)

Here we investigate the retention and spatio-temporal expression dynamics of duplicated genes predicted to regulate the floral transition in Brassica napus (oilseed rape, OSR). (jic.ac.uk)

A cross-talk between metabolism and gene expression. (unige.ch)

Within angiosperms such events have occurred repeatedly in many plant lineages. (jic.ac.uk)

On the other hand, the gene expressions of enzymes involved in proanthocyanidin synthesis were drastically decreased at véraison and remained extremely low even with ABA treatment. (scirp.org)

The DNA sequence from which a functional non-coding RNA is transcribed is often called an RNA gene. (wikipedia.org)

Antimicrobial drug resistance and capsule expression studies have demonstrated that gene transfer can occur from oral Streptococcus spp. (cdc.gov)
Similar evolutionary reasoning may explain why many people in malaria-prone parts of Africa carry gene variants linked to malaria resistance. (gnxp.com)
Can members of the microflora serve as reservoirs of resistance genes? (cdc.gov)

When T cells are activated, histone modifications take place which, on one hand, condense DNA and prevent transcription of genes ensuring longevity, while on the other hand open up and allow transcription of genes driving their inflammatory and killing function. (unige.ch)

The gene involved, Tbx5, is also implicated in human congenital heart disease, so our results also bring insight into human disease. (sciencedaily.com)
pendent of those associated with cretory ducts, columnar epithelia the KRAS gene is more frequent- other key mechanistic characteris- lining the gastrointestinal tract and ly mutated in human cancer, which tics of IARC Group 1 carcinogens. (who.int)

Unlike other brain tumors, meningiomas occur most often in female, Black and elderly patients. (ucsf.edu)
In a paper appearing Nov. 9, 2023 in Nature Medicine , the team concluded that just 1 in 5 patients with low-grade tumors (those less likely to regrow) may need radiation, while around 2 in 5 with higher-grade tumors may be better off without radiation, based on the results of the new gene-expression test. (ucsf.edu)
Raleigh, along with Magill and lead author William Chen , MD, decided to look at classifying tumors according to which of their genes are turned on and off, thereby offering clues to how aggressive they might be. (ucsf.edu)

However, the transcription level of the above genes was not associated with biological behaviours of gastric cancers. (wjgnet.com)

We found that the runaway expression of a single gene, white , which we used as a "utility tool" in our experiments, induces homosexual courtship among mature males. (nybooks.com)

Anatomy26

Organisms16

Diseases4

Chemicals and Drugs70

Analytical, Diagnostic and Therapeutic Techniques and Equipment34

Phenomena and Processes101

Disciplines and Occupations4

Information Science8

Health Care3

Differentially expressed6

Mutations17

Methylation7

Proteins8

Pathways4

Protein14

Naturally4

MRNA levels2

Autosomal3

Regulatory7

Regulation10

Genome6

Candidate genes2

Certain genes2

Differential expression1

Analyze3

Tumor4

Peripheral2

Antibiotic2

Tissues4

Genetic5

Molecular1

Homologous1

Ontology1

Inhibition2

Epigenetic changes4

Epigenetics1

Differences3

Modulate1

Defects1

Biotin4

Patterns of gene2

Virulence2

Microarray Analysis1

Species7

Levels4

Regulates3

Chromatin1

Tissue3

Clusters1

Suggests3

Findings3

Significantly1

Affects2

Researchers3

Mechanism6

Investigate1

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Repeatedly1

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Functional1

Resistance3

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Human2

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Single gene1