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  • incidence
  • In China, which has the largest number of smokers and lung cancer cases in the world, the acinar tissue architectural pattern is by far the most common histological subtype of adenocarcinoma, comprising about 40% of all adenocarcinomas, and its incidence has increased significantly in recent decades. (wikipedia.org)
  • lung
  • It is a common form of cancer occurring in the lung and prostate gland. (wikipedia.org)
  • Adenocarcinoma ("adeno" = "gland", "carcinoma" = cancer of epithelium) is the most common type of lung cancer in the U.S., Japan, and most of Western Europe, although it is the second most common form in Eastern parts of Europe (after squamous cell carcinoma). (wikipedia.org)
  • Acinar adenocarcinoma of the lung is a highly lethal disease. (wikipedia.org)
  • Lung cancer in never-smokers is almost universally NSCLC, with a sizeable majority being adenocarcinoma. (wikipedia.org)
  • Adenocarcinoma of the lung is currently the most common type of lung cancer in "never smokers" (lifelong non-smokers). (wikipedia.org)
  • Historically, adenocarcinoma was more often seen peripherally in the lungs than small cell lung cancer and squamous cell lung cancer, both of which tended to be more often centrally located. (wikipedia.org)
  • LCLC is, in effect, a "diagnosis of exclusion", in that the tumor cells lack light microscopic characteristics that would classify the neoplasm as a small-cell carcinoma, squamous-cell carcinoma, adenocarcinoma, or other more specific histologic type of lung cancer. (wikipedia.org)
  • primary
  • Primary signet-ring cell carcinoma of the urinary bladder is extremely rare and patient survival is very poor and occurs mainly in men ages 38 to 83. (wikipedia.org)
  • lesions occurred
  • Exposure-related significantly increased incidences of nonneoplastic lesions occurred in the respiratory tract of male and female mice, primarily in the 50 and 100 ppm groups. (nih.gov)
  • typically
  • Highly differentiated adenocarcinomas form SRCCs via a loss of adherens and tight junctions that typically separate MUC4, a mucin protein, and ErbB2, an oncogenic receptor. (wikipedia.org)
  • females
  • Significant increases in neutrophil counts occurred in 50 and 100 ppm males and 100 ppm females and were consistent with inflammation. (nih.gov)
  • Usually
  • Stiffness and spasms are usually limited to the legs and hyperlordoisis generally does not occur. (wikipedia.org)
  • NBTE usually occurs during a hypercoagulable state such as system-wide bacterial infection, or pregnancy, though it is also sometimes seen in patients with venous catheters. (wikipedia.org)
  • increases
  • Significant increases in the erythron occurred most consistently in the 100 ppm male and female groups on day 23 and at study termination. (nih.gov)
  • types
  • Both groups occur mainly (but not exclusively) in people over 40, and are slightly more common in men, but some rare sub-types mainly occur in women or children. (wikipedia.org)
  • A number of less common types also occur. (wikipedia.org)
  • The most common types of NSCLC are squamous cell carcinoma, large cell carcinoma, and adenocarcinoma, but there are several other types that occur less frequently. (wikipedia.org)
  • known
  • An anatomical variation can occur, known as a Phrygian cap, which is an innocuous fold in the fundus, named after its resemblance to the Phrygian cap. (wikipedia.org)
  • found
  • Duodenal tumours, adenomas, and adenocarcinomas were found in all treated groups of both sexes, with an even more significant dose relationship. (inchem.org)
  • syndrome
  • Compression of local structures occurs in advanced disease, leading to such problems as upper airway obstruction and superior vena cava syndrome. (wikipedia.org)
  • treatment
  • A dose-limiting toxicity (DLT) was defined as any grade 3 or 4 conatumumab-related or combination (panitumumab and conatumumab)-related adverse event, or grade 3 or 4 laboratory abnormality that occurred during the first 4 weeks (28 days) of treatment with panitumumab and conatumumab. (clinicaltrials.gov)
  • chance
  • The more divisions that have taken place, the greater chance there is for a mutation to occur that is cancerous in nature. (vetinfo.com)
  • A direct way of contracting this cancer is a smoker has a higher chance of CIN3 occurring which has the potential of forming cervical cancer. (wikipedia.org)
  • patient
  • Primary signet-ring cell carcinoma of the urinary bladder is extremely rare and patient survival is very poor and occurs mainly in men ages 38 to 83. (wikipedia.org)
  • another
  • citation needed] Another example occurs in activated T cell lymphocytes, i.e., when a T cell is induced to mature by binding to a peptide:MHC complex on a professional antigen-presenting cell and by the B7:CD28 costimulatory signal. (wikipedia.org)
  • rate
  • DNA damage, due to environmental factors and normal metabolic processes inside the cell, occurs at a rate of 10,000 to 1,000,000 molecular lesions per cell per day. (wikipedia.org)