• Chlamydiae are gram-negative, obligate intracellular bacteria. (medscape.com)
  • Chlamydia bacteria, which are present in (dried) excreta or feather dust, are transmitted through direct contact or inhalation. (cdc.gov)
  • A better understanding of C. trachomatis basic biology is important to eventually develop new ways to combat infections caused by these bacteria. (europa.eu)
  • Chlamydiae are nonmotile, obligate intracellular bacteria. (msdmanuals.com)
  • She subsequently became an independent NIH-funded investigator and Assistant Professor at Harvard, continuing to investigate host-pathogen relationships in the genital tract, but primarily focusing on the unique obligate intracellular bacteria, Chlamydia trachomatis . (lsuhsc.edu)
  • Chlamydiae are obligate intracellular bacteria responsible for pulmonary infections, ocular trachoma, sexually transmitted diseases, and infections of the genital tract in the pediatric and adult population. (unboundmedicine.com)
  • 15) Which of the following bacteria is responsible for the infection 'psittacosis' that is transmitted from the parrots to humans? (medicalbiochemist.com)
  • Members of the genus Chlamydia are obligate intracellular gram-negative bacteria that belong to the family Chlamydiaceae . (thenativeantigencompany.com)
  • Chlamydia trachomatis is a type of bacteria that can cause sexually transmitted infections (STIs) in both men and women. (drvikram.com)
  • Chlamydia is a sexually transmitted infection caused by bacteria. (virtualpsychcentre.com)
  • What bacteria causes Chlamydia trachomatis? (virtualpsychcentre.com)
  • It is caused by bacteria called Chlamydia trachomatis . (virtualpsychcentre.com)
  • Is chlamydia a virus or bacteria? (virtualpsychcentre.com)
  • Chlamydia (klah-MID-e-a) are obligate intracellular bacteria that are propagated and maintained through a phylum defining bi-phasic developmental cycle. (ku.edu)
  • We have identified a previously uncharacterized protein, CT622, unique to the Chlamydiaceae, in the absence of which most bacteria failed to establish a successful infection. (hal.science)
  • General Information: Bacteria belonging to the Chlamydiales group are obligate intracellular parasites of eukaryotic cells. (up.ac.za)
  • Pathogens, including fungi, viruses, parasites, or intracellular bacteria can induce and may benefit from lipid droplets in infected cells. (microbiologyresearch.org)
  • Some types of this bacteria cause the genital infection chlamydia. (diseasesdic.com)
  • However, the same bacteria that cause genital Chlamydia does not cause LGV. (diseasesdic.com)
  • The bacteria enter through a moist mucosal surface - most commonly, the rectum or vagina, but infections in the penis or mouth are also possible. (diseasesdic.com)
  • For Mukherjee, the paper was a revelation: not only did it identify the fastest way yet to target Golgi biology, it suggested that scientists could use intracellular bacteria "as a lens to understand basic processes inside the cell. (the-scientist.com)
  • And she gained a new appreciation for the myriad other types of intracellular bacteria, a diverse group that includes many medically significant pathogens such as Salmonella , Listeria, and Chlamydia , as well as the causative agents of tuberculosis and leprosy. (the-scientist.com)
  • Research on how intracellular bacteria take control of their hosts is not only informing scientists about how these microbes cause disease, but revealing secrets of mammalian biology, says Mukherjee, who now heads up a lab at the University of California (UC), San Francisco. (the-scientist.com)
  • Intracellular bacteria vary considerably in how dependent they are on their hosts. (the-scientist.com)
  • So-called facultative intracellular bacteria such as Listeria monocytogenes and Legionella pneumophila do not need to be inside a host cell to reproduce. (the-scientist.com)
  • By contrast, obligate intracellular bacteria such as Chlamydia trachomatis and Mycobacterium leprae do, and this trait makes them a challenge to culture and study in the lab. (the-scientist.com)
  • Chlamydiae are obligate intracellular bacteria with a biphasic developmental cycle that involves cell types adapted for extracellular survival and intracellular multiplication. (nih.gov)
  • The research in the Division of Microbiology & Parasitology comprises a wide range of topics including: bacterial motility and flagellar biogenesis, mechanisms of entry of bacteria into mammalian cells, bacterial toxin export and multi-drug efflux, regulation of gene expression during host-pathogen interaction, transmission, cell-cycle dynamics and virulence mechanisms in malaria parasites, host modulation by parasitic organisms and dynamics of parasitic worm infection in human populations. (cam.ac.uk)
  • Thus, intracellular bacteria frequently encode the capacity to regulate host lipogenesis as well as to modulate the lipid composition of host membranes. (microbialcell.com)
  • Microscopy analyses indicate that cholesterol regulates a step in L. pneumophila intracellular lifecycle that occurs after bacteria begin to replicate within an established intracellular niche. (microbialcell.com)
  • The obligate intracellular bacteria Chlamydia replicate within an intracellular vacuole, termed an inclusion. (pasteur.fr)
  • Yet, the chlamydiae are a much larger group of evolutionary ancient obligate intracellular bacteria that includes predominantly symbionts of protists and diverse animals. (univie.ac.at)
  • Genome Dynamics and Temperature Adaptation During Experimental Evolution of Obligate Intracellular Bacteria. (univie.ac.at)
  • Our results provide insights into the molecular evolution of intracellular bacteria under the constraints of strict host dependance and highly structured populations and suggest that for chlamydial symbionts of protists, temperature adaptation was facilitated through attenuation of symbiont infectivity as a tradeoff to reduce host cell burden. (univie.ac.at)
  • Researchers have catalogued »465 bird species affected by this pathogen, which mainly causes subclinical infections but sometimes results in acute disease and death ( 1 ). (cdc.gov)
  • Chlamydia trachomatis is an obligate intracellular human pathogen that exhibits stage-specific gene transcription throughout a biphasic developmental cycle. (plos.org)
  • Thus, it is thought that the success of C . trachomatis as a human pathogen may lie in its ability to survive these immunological stress situations by slowing growth and development until conditions in the cell have improved. (plos.org)
  • The postdoc project involves the implementation of a CRISPR/Cas9 screening approach to dissect the molecular composition of a recently identified novel pathway of programmed cell death induced during infection with the obligate intracellular bacterial pathogen Chlamydia trachomatis. (fems-microbiology.org)
  • Chlamydia trachomatis (C. trachomatis) is an obligate intracellular gram-negative pathogen with a significantly reduced genome. (uni-wuerzburg.de)
  • The present work is the first study describing a global interactome of RNAs and proteins in C. trachomatis providing the basis for future interaction studies in the field of this pathogen. (uni-wuerzburg.de)
  • C. trachomatis has been most extensively studied because of its association with ocular trachoma and its prevalence as a sexually transmitted pathogen. (dergisi.org)
  • Chlamydia trachomatis, an obligate intracellular human pathogen, is one of four bacterial species in the genus Chlamydia. (chlamydiaexplained.com)
  • Rather, it was produced by a tiny intracellular bacterium known as Legionella pneumophila , the pathogen behind a serious lung infection called Legionnaire's disease. (the-scientist.com)
  • Nineteen serotypes of this pathogen can cause infection in pregnant women and neonates. (analesdepediatria.org)
  • Due to its capability of causing systemic infection with acute to chronic course in poultry, pet birds and some mammals, as well as its worldwide dissemination [ 2 ], it is probably the most important veterinary chlamydial pathogen. (biomedcentral.com)
  • Here, we used the Acanthamoeba symbiont Protochlamydia amoebophila, a distant relative of the human pathogen Chlamydia trachomatis and representative of a large group of protist-associated environmental chlamydiae, as a model to study how obligate intracellular symbionts evolve and adapt to elevated temperature, a prerequisite for the pivotal evolutionary leap from protist to endothermic animal hosts. (univie.ac.at)
  • Although C pneumoniae infections occur every year, epidemiologic studies suggest a 4-year cycle in the incidence of C pneumoniae pneumonia. (medscape.com)
  • 8) What is the most sensitive laboratory diagnostic tests for Chlamydia pneumoniae ? (medicalbiochemist.com)
  • There are three main species of Chlamydia causing human infection: Chlamydia trachomatis, Chlamydia pneumoniae (also known as Chlamydophila pneumoniae), and Chlamydia psittacci. (virtualpsychcentre.com)
  • C. trachomatis and C. pneumoniae, have an immense impact on public health in the US and globally. (ku.edu)
  • C. pneumoniae infections are a common cause of community acquired pneumonia. (ku.edu)
  • While the association between athlerosclerosis and C. pneumoniae infections is still under investigation, numerous observations support this and include animal studies, shared immuno-pathology, and organism associated with athlerosclerotic lesion. (ku.edu)
  • Chlamydophila pneumoniae (formerly known as Chlamydia pneumoniae) causes respiratory infections with a mild course. (athenslab.gr)
  • In the present study we have identified a selective inhibitor of PknD and show that this compound blocks phosphorylation of CdsD in vitro, retards the intracellular growth rate and decreases Mizoribine solubility dmso the number of infectious C. pneumoniae produced following infection of HeLa cells. (mek-inhibitors.com)
  • The high prevalence of asymptomatic gonococcal and chlamydial infections is one of the greatest obstacles to STI control, especially in developing countries, where partner notification is difficult. (bmj.com)
  • To study the function of known effectors, we focused on the C. trachomatis Inc proteins, an important group of potential chlamydial virulence factors. (europa.eu)
  • Those guidelines highlighted the prevalence and morbidity of chlamydial infections and stressed the need to include antibiotics effective against chlamydia when treating patients for urethritis, mucopurulent cervicitis, and pelvic inflammatory disease. (cdc.gov)
  • In addition, these recommendations propose a national strategy for reducing the morbidity of chlamydial infections by detection and treatment and through the prevention of transmission to uninfected persons. (cdc.gov)
  • Because chlamydial infections are common among adolescents and young adults throughout the United States, health-care providers and other agencies serving these groups should become more involved if a sufficiently large proportion of the chlamydia-infected population is to be reached. (cdc.gov)
  • More than 4 million chlamydial infections occur annually (2,3). (cdc.gov)
  • In the United States, published studies of sexually active females screened during visits to health-care providers indicate that age is the sociodemographic factor most strongly associated with chlamydial infection. (cdc.gov)
  • The prevalence of chlamydial infection also has been higher among those patients who live in inner cities, have a lower socioeconomic status, or are black (5-11). (cdc.gov)
  • LGV is distinct from other chlamydia serovars causing either common genital chlamydial disease (serovars D-K) or trachoma (serovars A-C). (hopkinsguides.com)
  • Chlamydial species can cause persistent infection, which is often subclinical. (msdmanuals.com)
  • It can also be transmitted from a mother with an untreated chlamydial cervical infection to her newborn during childbirth (1). (genetrack.ca)
  • Chlamydial infections can also facilitate the transmission of HIV infection (6), and in rare cases can cause reactive arthritis (7). (genetrack.ca)
  • 2) Which of the following is a common specimen used for the diagnosis of sexually transmitted chlamydial infections that occur in both men and women? (medicalbiochemist.com)
  • In women, chlamydial infection can spread to the uterus or fallopian tubes and cause pelvic inflammatory disease (PID), according to the CDC. (virtualpsychcentre.com)
  • In men, chlamydial infection of the lower genital tract causes urethritis and, on occasion, epididymitis. (chlamydiaexplained.com)
  • Respiratory infections are probably the most common of all chlamydial infections. (athenslab.gr)
  • Massive perinatal infection of the newborn can lead to interstitial chlamydial pneumonia. (athenslab.gr)
  • Understanding the initial events in chlamydial differentiation, including the transition in properties of the endocytic vesicle to one which intersects an exocytic pathway, remains a significant challenge in deciphering the pathogenic mechanisms of chlamydiae. (nih.gov)
  • Our data also rule out an effect of compound D7 on the MEK/ERK signaling pathway required for chlamydial infection and intracellular growth. (mek-inhibitors.com)
  • Most C. avium and C. gallinacea infections in birds are subclinical, and the zoonotic potential of these species is unknown ( 3 ). (cdc.gov)
  • In 2016, an outbreak of C. avium infection occurred among 11 Picazuro pigeons ( Patagioenas picazuro ) housed in an aviary with other bird species in the Netherlands. (cdc.gov)
  • To screen for novel T3S effectors of C. trachomatis, we used Yersinia enterocolitica as a genetically tractable surrogate bacterial species assembling a T3S apparatus, which has been shown to recognise heterologous T3S substrates. (europa.eu)
  • As some C. trachomatis isolates are reported not to carry cryptic plasmid or have deletion(s) in it [7], "RealLine Chlamydia trachomatis/ Neisseria gonorrhoeae" assay kit detects two DNA fragments from gyrA gene and cryptic plasmid, specific to C. trachomatis species. (roboscreen.com)
  • Three species of Chlamydia cause human disease, including sexually transmitted infections and respiratory infections. (msdmanuals.com)
  • This species causes infection that leads to blindness and sexually transmitted diseases in humans. (up.ac.za)
  • Here we identify SNARE-like motifs in the inclusion protein IncA, which are conserved among most Chlamydia species. (pasteur.fr)
  • The "Ca. Clavichlamydia salmonicola" genome harbors genes that so far have been exclusively found in Chlamydia species suggesting that basic mechanisms important for the interaction with chordate hosts have evolved stepwise in the history of chlamydiae. (univie.ac.at)
  • Examples of these pathogens include Chlamydiae, Chlamydophila species, and rickettsiae. (msdmanuals.com)
  • Neonates born of infected mothers can develop inclusion conjunctivitis, nasopharyngeal infections and pneumonia due to C. trachomatis [5]. (roboscreen.com)
  • C trachomatis can also cause pneumonia, primarily in infants and young children. (medscape.com)
  • Reports document cases of pneumonia due to C trachomatis in immunocompromised adults and laboratory workers. (medscape.com)
  • For patient education information, see eMedicineHealth's Sexual Health Center, as well as Chlamydia and Bacterial Pneumonia. (medscape.com)
  • Although primary infection pneumonia is more common in persons aged 7-40 years, reinfection pneumonia is more common in elderly persons. (medscape.com)
  • Neonatal Pneumonia Neonatal pneumonia is lung infection in a neonate. (msdmanuals.com)
  • C. trachomatis can cause afebrile pneumonia in 10-20% of infants born to infected mothers. (unboundmedicine.com)
  • Pneumonia may develop in up to 30% of infants with nasopharyngeal infection. (unboundmedicine.com)
  • 12) When do the symptoms of neonatal pneumonia in babies start to show caused by Chlamydia trachomatis ? (medicalbiochemist.com)
  • Psittacosis is a systemic infection that frequently causes pneumonia. (dergisi.org)
  • C. trachomatis can also be transmitted to babies born to infected untreated mothers during childbirth, causing conjunctivitis or pneumonia. (thenativeantigencompany.com)
  • It is primarily transmitted through sexual contact and can also be passed from mother to child during childbirth, causing eye infections or pneumonia in newborns. (drvikram.com)
  • Pregnant women can pass chlamydia to their baby, who may develop an eye infection or pneumonia. (chlamydiaexplained.com)
  • Infection occurs when filarial parasites are transmitted to humans through mosquitoes. (who.int)
  • This phylum includes obligate intracellular parasites, such as Chlamydia trachomatis, responsible for various human infections, including sexually transmitted diseases. (microbiologynote.com)
  • Chlamydiae are obligate intracellular parasites with a unique biphasic life cycle. (dergisi.org)
  • The Host-Parasite Interactions Section studies the basic molecular and cellular biology of chlamydiae and other obligate intracellular parasites. (nih.gov)
  • Whereas the majority of intracellular parasites are thought to block maturation of the endocytic vesicle to a lysosome, chlamydiae rapidly dissociate themselves from this pathway and establish a functional interaction with an exocytic pathway that delivers sphingolipids and cholesterol from the Golgi apparatus to the plasma membrane. (nih.gov)
  • A widely available diagnostic test which allowed prompt and effective treatment of asymptomatic patients could reduce the prevalence of these infections, prevent complications, and reduce the incidence of HIV infection, whose transmission they facilitate. (bmj.com)
  • As many people in the population are infected and the significant proportion of infection is asymptomatic, the diagnosis is often established by screening, which is recommended to perform regularly in sexually active young women, in other people from higher risk groups, and at the first prenatal visit [6]. (roboscreen.com)
  • Symptoms include purulent exudates from penis and painful urination in men, and abnormal vaginal discharge in women, although often the infection is asymptomatic. (roboscreen.com)
  • Lymphogranuloma Venereum (LGV) Lymphogranuloma venereum (LGV) is a disease caused by 3 unique strains of Chlamydia trachomatis and characterized by a small, often asymptomatic skin lesion, followed by regional lymphadenopathy. (msdmanuals.com)
  • However, 70-80% of women with C. trachomatis genital tract infection remain asymptomatic. (thenativeantigencompany.com)
  • are asymptomatic (person infected and contagious but haven't developed symptoms yet to encourage clinical interactions and diagnosis) indicating well over two million new infections annually in the US. (ku.edu)
  • Gonococcal infection in women is often asymptomatic. (pediagenosis.com)
  • Clinically, asymptomatic infections are common. (athenslab.gr)
  • Infection can also be asymptomatic. (health.mil)
  • It is an obligate intracellular parasite, for which humans are the only host [1]. (roboscreen.com)
  • Chlamydia trachomatis is a gram-negative, obligate intracellular bacterium that infects humans. (drvikram.com)
  • The origins of both sexually transmitted and ocular C. trachomatis are unclear, but it seems likely that they evolved with humans and shared a common ancestor with environmental chlamydiae some 700 million years ago. (virtualpsychcentre.com)
  • While the developmental cycle is intriguing, it is also essential for Chlamydia to cause disease in humans. (ku.edu)
  • Chlamydia trachomatis are pathogenic microorganisms that affect exclusively humans. (athenslab.gr)
  • Subsequently meat, dairy products and water serve as key vehicles in the transmission of MAP infection to humans (from farm to fork) who have a genetic predisposition, thus leading to the development of CD. (wjgnet.com)
  • Infection with the obligate intracellular organism Chlamydia trachomatis (immunotypes D-K) frequently associates with other lower genitourinary (GU) tract infections. (medscape.com)
  • Infection by this organism is insidious -- symptoms are absent or minor among most infected women and many men. (cdc.gov)
  • In addition, Grad-seq for C. trachomatis was established to obtain a global interactome of the RNAs and proteins of this intracellular organism. (uni-wuerzburg.de)
  • When pregnant women have a C trachomatis infection of the cervix, the organism is transmitted when the infant passes through the infected birth canal. (medscape.com)
  • The new Swedish variant of C trachomatis, which eluded NAATs, was detected because the organism could be cultured. (medscape.com)
  • 10) Name the organism given below which is frequently associated with urethritis apart from Chlamydia trachomatis ? (medicalbiochemist.com)
  • Due to antibiotic resistence profiles, a parenteral cephalosporin plus doxycycline or azithromycin is currently first-line therapy for uncomplicated infections, but the choice of antibiotic evolves with resistence profiles and the propensity for the organism to be associated with other STDs. (pediagenosis.com)
  • R. rickettsii is a small, obligate, intracellular, Gram-negative organism maintained in its tick host through transovarial transmission. (nih.gov)
  • However, these symptoms are nonspecific and may also be associated with infection of the lower genitourinary tract (urethra, vagina) or with noninfectious conditions such as bladder carcinoma, urethral diverticulum, and calculi. (medscape.com)
  • Complications from untreated genital-tract-localized infection can cause pelvic inflammatory disease, ectopic pregnancy and infertility in women, and epididymitis and infertility in men [12, 13]. (roboscreen.com)
  • Adequate surveillance and treatment of C. trachomatis colonizing the genital tract of pregnant women is the best way of preventing disease in the infant. (unboundmedicine.com)
  • Serovars D-K are responsible for bacterial sexually transmitted genital tract infections in women and men. (thenativeantigencompany.com)
  • This is the most common type of chlamydia that affects the genital tract, including the cervix, urethra, anus, and throat. (drvikram.com)
  • Chlamydia trachomatis causes both genital tract and ocular diseases. (ku.edu)
  • There are also non-STI causes such as a lower urinary tract infection or, in women, endometriosis. (chlamydiaexplained.com)
  • Pelvic inflammatory disease (PID) is a term used to describe infection of the upper genital tract, including endometritis, salpingitis and peritonitis. (pediagenosis.com)
  • The surface damage caused by the gonococcus allows other pathogens, such as chlamydia, to gain access to the upper reproductive tract and cause multiorganism PID. (pediagenosis.com)
  • It is an infection of the urinary tract, throat and/or rectum. (diseasesdic.com)
  • Several characteristics of the female genital tract make it suitable for inoculation, establishment of infection, and systemic spread of the virus, which causes local changes that may favor the development of infections by other pathogens, often called sexually transmitted diseases (STDs). (hindawi.com)
  • 23-55% of all cases of nongonococcal urethritis in men are caused by C. trachomatis . (unboundmedicine.com)
  • These infections can lead to acute (e.g. urethritis), chronic (e.g. pelvic inflammatory disease), and life threatening/preventing disease pathologies (e.g. ectopic pregnancies and sterility). (ku.edu)
  • Urethritis is secondary to C. trachomatis infection in approximately 15 to 55 percent of men, although the prevalence is lower among older men. (chlamydiaexplained.com)
  • The diagnosis of nongonococcal urethritis can be confirmed by the presence of a mucopurulent discharge from the penis, a Gram stain of the discharge with more than five white blood cells per oil-immersion field, and no intracellular gram-negative diplococci. (chlamydiaexplained.com)
  • Between 20 and 30% of heterosexual men with symptomatic gonococcal urethritis are simultaneously infected with Chlamydia trachomatis . (pediagenosis.com)
  • Uncomplicated urogenital gonococcal infection in women may present as dysuria from urethritis, vaginal discharge from cervicitis, or purulent drainage from the Skene or Bartholin glands at the vaginal introitus. (pediagenosis.com)
  • Chlamydia trachomatis is responsible for 30-60% of non-gonococcal urethritis (NGU) cases in men. (athenslab.gr)
  • Urethral discharge, dysuria, and exposure to a sexually transmitted infection (STI) are frequent presentations of urethritis in the male population. (medscape.com)
  • 9] Recurrent urethritis may occur from reinfection, therapeutic failure, or "venereophobia," an old term describing fear of recurrence where men can induce urethral inflammation and drainage (negative by white blood cell or Gram stain criteria) by repeatedly milking the urethra, checking for infection. (medscape.com)
  • The most common cause of nongonococcal urethritis (NGU) is Chlamydia trachomatis (15-40% of cases), followed by Mycoplasma genitalium (15-20% of cases). (medscape.com)
  • Neisseria gonorrhoeae, the cause of gonococcal urethritis, is a gram-negative intracellular diplococcus. (medscape.com)
  • 5) Which of the following antibiotics are the drug of choice or are the first line treatment for chlamydia infection? (medicalbiochemist.com)
  • The main Ayurvedic treatment for chlamydia involves balancing these doshas through a combination of diet, lifestyle changes, and herbal remedies. (drvikram.com)
  • Because the liver and kidney samples of 7 pigeons tested positive for antibodies against Chlamydia , we submitted samples from all 11 pigeons and the 3 pooled fecal samples for further testing with real-time PCR selective for the 23S gene of Chlamydiaceae ( 5 ) and a duplex real-time PCR selective for C. gallinacea and C. avium ( 3 , 6 ). (cdc.gov)
  • Members of the Chlamydiaceae family are small, non-motile, Gram-negative, obligate intracellular organisms that grow in the host cell cytoplasm. (athenslab.gr)
  • Chlamydia trachomatis is the leading cause of both bacterial sexually transmitted infection and infection-derived blindness world-wide. (plos.org)
  • This is the most common reportable sexually transmitted infection in the United States. (unboundmedicine.com)
  • Chlamydia, or more specifically a chlamydia infection, is a sexually transmitted infection caused by the bacterium Chlamydia trachomatis. (virtualpsychcentre.com)
  • Older women at increased risk for an infection, such as those with a new sex partner, more than one sex partner, a sex partner with concurrent partners, or a sex partner who has a sexually transmitted infection, should also be screen regularly. (chlamydiaexplained.com)
  • You can have more than one sexually transmitted infection at the same time, so you will need to be tested for other infections. (chlamydiaexplained.com)
  • RealLine Chlamydia trachomatis / Neisseria gonorrhoeae" assay kit is intended for the detection of Chlamydia trachomatis and Neisseria gonorrhoeae DNA in human specimens: urine, semen, prostate fluid, swabs of the epithelial cells (urethral, cervical, vaginal), using the method of real-time polymerase chain reaction (PCR) with fluorescence detection of amplified product. (roboscreen.com)
  • LGV strains infect macrophages and spread to lymph nodes which are different from other C. trachomatis strains that are usually restricted to the epithelial cells of the conjunctiva and urogenital mucosa. (hopkinsguides.com)
  • Chlamydiae are small gram-negative obligate intracellular microorganisms that preferentially infect squamocolumnar epithelial cells. (virtualpsychcentre.com)
  • Invasion of epithelial cells by the obligate intracellular bacterium Chlamydia trachomatis results in its enclosure inside a membrane-bound compartment termed an inclusion. (hal.science)
  • Chlamydiae access the body by invading the same epithelial cells of the endocervix, urethra, endometrium, fallopian tubes, rectum and conjunctivae that are host to the gonococcus. (pediagenosis.com)
  • This bacterium shares a unique biphasic lifecycle in which it alternates between the infectious, metabolically inert elementary bodies (EB) and the non-infections, metabolically active replicative reticular bodies (RB). (uni-wuerzburg.de)
  • Discussion Chlamydiae are obligate intracellular pathogens that have a unique biphasic developmental cycle. (mek-inhibitors.com)
  • Most C. trachomatis strains have a multicopy extrachromosomal cryptic plasmid, which is widely used as the target for PCR testing. (roboscreen.com)
  • This tropism likely accounts for the differing clinical features and severity of LGV infection when compared with other strains. (hopkinsguides.com)
  • Rectal infection with L2 strains can cause severe proctocolitis that can mimic acute inflammatory bowel disease in MSM who are HIV-positive. (msdmanuals.com)
  • Chlamydia trachomatis strains are divided into three biovars, which are further divided into fifteen serovars A, B, Ba, serovars C-K and serovars L1-L3. (thenativeantigencompany.com)
  • Antibiotic resistance is a major public health threat and while two major classes of antibiotics (e.g., macrolides and tetracyclines) are effective at clearing Chlamydia infections, resistance to one of these has already been observed in pigs strains (yes…there is pig Chlamydia ! (ku.edu)
  • Lymphogranuloma venereum (LGV) is a sexually transmitted disease (STD) caused by three strains of the bacterium chlamydia trachomatis . (diseasesdic.com)
  • If not diagnosed and treated properly, infection with R. rickettsii results in a severe and potentially life threatening disease, although strains of R. rickettsii vary dramatically in their virulence in animal model systems and severity of human disease. (nih.gov)
  • Molecular testing for Chlamydia is used for the rapid and highly accurate laboratory diagnosis of all infections caused by these microorganisms. (athenslab.gr)
  • In 1994 the Rockefeller Foundation offered a prize of US$1 million for the development of a simple, rapid point of care test for Neisseria gonorrhoeae and Chlamydia trachomatis infection. (bmj.com)
  • A recent inventory carried out by the SDI, which is presently based in the UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases (TDR) at the World Health Organization, found that over 40 rapid tests for syphilis, C trachomatis , and N gonorrhoeae are on the market in 2001. (bmj.com)
  • RealLine Chlamydia trachomatis / Neisseria gonorrhoeae" assay kit detects a part of PivNG (pilin gene inverting protein homolog) gene sequence, specific to N. gonorrhoeae . (roboscreen.com)
  • Neisseria gonorrhoeae and C. trachomatis are the two pathogens most commonly isolated from women with positive cultures for PID. (pediagenosis.com)
  • There are many similarities between the infections caused by N. gonorrhoeae and Chlamydia trachomatis (CT) . (pediagenosis.com)
  • Rescreening for C trachomatis and N gonorrhoeae is recommended 3 months after treatment. (medscape.com)
  • Eosinophilic cystitis, a rare condition, can be associated with allergic and autoimmune diseases such as lupus, parasitic infection, and systemic peripheral eosinophilia, such as in idiopathic hypereosinophilic syndrome . (medscape.com)
  • May cause systemic disease rather than superficial mucosal infection. (hopkinsguides.com)
  • LGV is a rare type of chlamydia that can cause a systemic infection, including swollen lymph nodes, ulcers, and abscesses. (drvikram.com)
  • LGV is an invasive, systemic infection, and if it is not treated early, LGV proctocolitis can lead to chronic, colorectal fistulas and strictures. (diseasesdic.com)
  • What is life cycle of chlamydia? (virtualpsychcentre.com)
  • The life cycle of chlamydia can be divided into two distinct phases: an extracellular phase , in which they do not proliferate and are infectious, and a mandatory intracellular phase , during which they multiply and are non-infectious. (athenslab.gr)
  • Chlamydia can infect both men and women and can affect various parts of the body, including the cervix, urethra, anus, throat, and eyes. (drvikram.com)
  • Rarely, disseminated gonococcal infection develops in untreated patients resulting in infectious arthritis and endocarditis [14]. (roboscreen.com)
  • According to the CDC, C. trachomatis has the highest incidence of infection among ALL reportable infectious diseases in the US! (ku.edu)
  • They share a unique hydrophobic motif thought to target them to the membrane of the large vacuole where Chlamydia resides intracellularly. (europa.eu)
  • Chlamydiae undergo their developmental cycle entirely within a parasitophorous vacuole, termed an inclusion, that is isolated from established routes of endocytic vesicle trafficking. (nih.gov)
  • Granulomatous cystitis due to Mycobacterium tuberculosis infection is often secondary to primary kidney involvement. (medscape.com)
  • 2 Moreover, immediate treatment will reduce the risk of complications and prevent further transmission of the infection. (bmj.com)
  • What are the long-term complications of chlamydia? (genetrack.ca)
  • If left untreated, chlamydia can live in the body and lead to a variety of complications. (chlamydiaexplained.com)
  • It is often caused by an untreated STD infection, such as chlamydia, which moves upwards from the vagina/cervix into the reproductive organs. (genetrack.ca)
  • In women, C. trachomatis infects the cervix which may lead to cervicitis. (thenativeantigencompany.com)
  • Chlamydia can be diagnosed through a simple test that involves collecting a urine sample or swab from the cervix, urethra, anus, or throat. (drvikram.com)
  • This disease causes a chronic keratoconjunctivitis resulting from the obligate intracellular bacterium Chlamydia trachomatis . (medscape.com)
  • The tendency to chronic inflammation is typical, and chronic persistent infection may occur if neonatal infections remain untreated. (medscape.com)
  • Since chronic Ctr infections are extremely difficult to treat, there is an urgent need for more effective therapeutics. (bvsalud.org)
  • Some infections can lead to infertility and chronic debilitating disease. (lecturio.com)
  • It is estimated that 400 million people suffer from chronic infection (they are carriers) and that it has caused blindness in 6 million. (athenslab.gr)
  • Chlamydia infections of the rectum may lead to proctitis, rectal pain, discharge and/or bleeding (2). (genetrack.ca)
  • The Chlamydia developmental cycle is fascinating and there are many fundamental aspects that are still poorly understood. (ku.edu)
  • Then, we selected 48 genes that may encode uncharacterised effectors (e. g. no detectable amino acid identity to other proteins or with a particular putative biochemical activity) from the genome of C. trachomatis strain L2/434/Bu. (europa.eu)
  • Chlamydia trachomatis is a gram-negative, obligate intracellular parasite that is linked to several diseases. (medscape.com)
  • Chlamydia trachomatis is a small gram-negative, obligate intracellular parasite that is deficient in energy metabolism. (medscape.com)
  • These are small, gram-negative, obligate intracellular organisms. (medscape.com)
  • Reactive Arthritis Reactive arthritis is an acute spondyloarthropathy that often seems precipitated by an infection, usually genitourinary or gastrointestinal. (msdmanuals.com)
  • Bacterial cystitis is most commonly the result of an ascending infection through the urethra caused by the patient's own enteric microbiota. (medscape.com)
  • In men, the most common manifestation of C. trachomatis infection is inflammation of the urethra (about 50% of cases) [4]. (roboscreen.com)