Obligate intracellular bacterium chlamydia trachomatis chlamydial chlamydia trachomatis. Medical search. Frequent questions

Chlamydia psittaci is a bacterium that can be transmitted from pet birds to humans. (cdc.gov)
Chlamydia (C.) psittaci , the causative agent of avian chlamydiosis and human psittacosis, is a genetically heterogeneous species. (biomedcentral.com)
Chlamydia (C.) psittaci is known as the etiological agent of avian chlamydiosis and human psittacosis [ 1 ]. (biomedcentral.com)
Like other chlamydiae, C. psittaci can also cause asymptomatic infections. (biomedcentral.com)
Like all chlamydial organisms, C. psittaci is an obligate intracellular bacterium distinguished by a biphasic developmental cycle comprising extracellular and intracellular stages. (biomedcentral.com)
7) All of the statements given below are correct about Chlamydia psittaci , EXCEPT ? (medicalbiochemist.com)
They include the genera Chlamydia (of which the type species is Chlamydia trachomatis) and Chlamydophila (eg, Chlamydophila pneumoniae and Chlamydophila psittaci). (virtualpsychcentre.com)
The suspension array correctly identified antibodies against various Chlamydia species in sera from experimentally infected mice, and was also able to differentiate between antibodies against C. psittaci and C. gallinacea in sera from experimentally infected chickens. (biomedcentral.com)
In birds, C. psittaci infections can result in mild to severe disease, depending on the avian species and the Chlamydia strain, whereas an infection in humans can lead to severe pneumonia, i.e. psittacosis [ 7 ]. (biomedcentral.com)
The goal of this study is to investigate if it is possible to develop a serological test that, in chicken serum, can differentiate between antibodies against different Chlamydia species, particularly C. psittaci and C. gallinacea , using peptides as antigens. (biomedcentral.com)
Chlamydia psittaci infection among humans (psittacosis) and pet birds (avian chlamydiosis), also known as parrot disease, parrot fever, and ornithosis, is a zoonotic bacterial disease. (health.mil)
Recently Chlamydia psittaci has been identified in Ocular Adnexa MALT lymphomas, with variable frequence dependently from geographic areas. (biomedcentral.com)
Moreover Chlamydia psittaci could promote chromosomal aberration either through genetic instability as a consequence of induced proliferation and probably through DNA oxidative damage. (biomedcentral.com)
In this review we analyse the most relevant features of Ocular adnexa MALT lymphomas, underlining specific biological characteristics mainly related to the potential role of Chlamydia psittaci in lymphomagenesis. (biomedcentral.com)

citation needed] Clinical signs and symptoms of C. trachomatis infection in the genitalia present as the chlamydia infection, which may be asymptomatic or may resemble a gonorrhea infection. (wikipedia.org)
C. trachomatis in the lungs presents as the chlamydia pneumoniae respiratory infection and can affect all ages. (wikipedia.org)
Lymphogranuloma venereum (LGV) is a sexually transmitted infection (STI) caused by specific serovars of Chlamydia trachomatis (L1, L2, L3). (medscape.com)
Chlamydial species can cause persistent infection, which is often subclinical. (msdmanuals.com)
It can also be transmitted from a mother with an untreated chlamydial cervical infection to her newborn during childbirth (1). (genetrack.ca)
Chlamydial infections can also facilitate the transmission of HIV infection (6), and in rare cases can cause reactive arthritis (7). (genetrack.ca)
It is often caused by an untreated STD infection, such as chlamydia, which moves upwards from the vagina/cervix into the reproductive organs. (genetrack.ca)
Untreated chlamydia during pregnancy is associated with a 50-70% risk of passing the infection to the newborn during childbirth. (genetrack.ca)
Chlamydia trachomatis is the leading cause of both bacterial sexually transmitted infection and infection-derived blindness world-wide. (plos.org)
Some types of this bacteria cause the genital infection chlamydia. (diseasesdic.com)
Due to its capability of causing systemic infection with acute to chronic course in poultry, pet birds and some mammals, as well as its worldwide dissemination [ 2 ], it is probably the most important veterinary chlamydial pathogen. (biomedcentral.com)
5) Which of the following antibiotics are the drug of choice or are the first line treatment for chlamydia infection? (medicalbiochemist.com)
15) Which of the following bacteria is responsible for the infection 'psittacosis' that is transmitted from the parrots to humans? (medicalbiochemist.com)
OBJECTIVES: To measure the effectiveness of chlamydia control strategies, we must estimate infection incidence over time. (cdc.gov)
CONCLUSIONS: Our method can be used to estimate the number of chlamydia infections each year, and thus whether infection incidence increases or decreases over time and after policy changes. (cdc.gov)
Furthermore, our results suggest that clearance via medical intervention may lead to short-term or no seroconversion, and the duration of untreated chlamydial infection may vary with age, underlining the complexity of chlamydial infection dynamics. (cdc.gov)
Chlamydia is a sexually transmitted infection caused by bacteria. (virtualpsychcentre.com)
There are three main species of Chlamydia causing human infection: Chlamydia trachomatis, Chlamydia pneumoniae (also known as Chlamydophila pneumoniae), and Chlamydia psittacci. (virtualpsychcentre.com)
In women, chlamydial infection can spread to the uterus or fallopian tubes and cause pelvic inflammatory disease (PID), according to the CDC. (virtualpsychcentre.com)
Chlamydia, or more specifically a chlamydia infection, is a sexually transmitted infection caused by the bacterium Chlamydia trachomatis. (virtualpsychcentre.com)
According to the CDC, C. trachomatis has the highest incidence of infection among ALL reportable infectious diseases in the US! (ku.edu)
Despite excellent educational and awareness programs, conditional prevention strategies are insufficiently addressing the public health challenge associated with Chlamydia infection rates. (ku.edu)
The available differentiating tests for Chlamydia are based on detection of genetic material and only give information about the actual infection status, but reveal nothing of past infections. (biomedcentral.com)
Infection with Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), or both, may lead to PID and associated morbidities including infertility, ectopic pregnancy, and chronic pelvic pain. (microbialcell.com)
Transcriptional profiling that compared systemic responses of women with chlamydial PID to women with local cervical infection, identified specific, disease-associated inflammatory pathways [6] and revealed how NG co-infection depressed developing immunity. (microbialcell.com)
Gonorrhea is a sexually transmitted infection (STI) caused by the gram-negative bacteria Neisseria gonorrhoeae (N. gonorrhoeae). (lecturio.com)
Although specific immune responses are provoked after a chlamydial infection, persistent infection often occurs ( 22 , 23 ). (silverchair.com)
Differences in somatometric measurements and clinical variables in newborns with respiratory distress and infection between different Chlamydia trachomatis genotypes. (analesdepediatria.org)
We tested 1062 bronchial lavage samples from neonates with respiratory distress syndrome for Chlamydia infection. (analesdepediatria.org)

Neisseria gonorrhoeae and C. trachomatis are the two pathogens most commonly isolated from women with positive cultures for PID. (pediagenosis.com)
The surface damage caused by the gonococcus allows other pathogens, such as chlamydia, to gain access to the upper reproductive tract and cause multiorganism PID. (pediagenosis.com)
1) Which of the following Chlamydia spp are human pathogens? (medicalbiochemist.com)
4) Chlamydia is one of the major pathogens that cause sexually transmitted diseases. (medicalbiochemist.com)
Obligate intracellular pathogens (e.g. (amboss.com)
Pathogens, including fungi, viruses, parasites, or intracellular bacteria can induce and may benefit from lipid droplets in infected cells. (microbiologyresearch.org)
We report that chlamydiae, which are obligate intracellular bacterial pathogens, can inhibit interferon (IFN)-γ-inducible major histocompatibility complex (MHC) class II expression. (silverchair.com)
Many intracellular pathogens have evolved various strategies for inhibiting MHC molecule expression on infected cells to avoid T lymphocyte recognition. (silverchair.com)
This is because IFN-γ induction is often required to upregulate MHC class II molecules on nonprofessional APCs, such as epithelial cells, that are usually the natural targets of intracellular pathogens. (silverchair.com)
It has been demonstrated that IFN-γ- inducible MHC class II expression is inhibited in cells infected with various intracellular pathogens ( 13 - 18 ), which suggests that suppression of IFN-γ-inducible MHC class II may represent an immune evasion strategy used by intracellular pathogens. (silverchair.com)
Chlamydiae are bacterial pathogens of very significant public health concern due to extensive morbidity, especially associated with female reproductive health. (biomedcentral.com)

In addition to the chromosome that contains most of the genome, nearly all C. trachomatis strains carry a 7.5 kilobase plasmid that contains 8 genes. (wikipedia.org)
The role of this plasmid is unknown, though strains without the plasmid have been isolated, suggesting it is not required for survival of the bacterium. (wikipedia.org)
C. trachomatis strains are generally divided into three biovars based on the type of disease they cause. (wikipedia.org)
Lymphogranuloma Venereum (LGV) Lymphogranuloma venereum (LGV) is a disease caused by 3 unique strains of Chlamydia trachomatis and characterized by a small, often asymptomatic skin lesion, followed by regional lymphadenopathy. (msdmanuals.com)
Plaque assays have been used to clonally segregate laboratory-adapted C. trachomatis strains from mixed infections, but no assays have been reported to segregate clones from recent clinical samples. (cdc.gov)
Although a few studies have described methods for segregating clones of laboratory-adapted C. trachomatis clinical and reference strains ( 12 , 15 , 16 ), none has clonally purified all 19 C. trachomatis reference strains nor determined optimal methods to clonally segregate clinically mixed samples. (cdc.gov)
Lymphogranuloma venereum (LGV) is a sexually transmitted disease (STD) caused by three strains of the bacterium chlamydia trachomatis . (diseasesdic.com)
Antibiotic resistance is a major public health threat and while two major classes of antibiotics (e.g., macrolides and tetracyclines) are effective at clearing Chlamydia infections, resistance to one of these has already been observed in pigs strains (yes…there is pig Chlamydia ! (ku.edu)
LGV strains infect macrophages and spread to lymph nodes which are different from other C. trachomatis strains that are usually restricted to the epithelial cells of the conjunctiva and urogenital mucosa. (hopkinsguides.com)

C. trachomatis along with C. pneumoniae have been found to infect humans to a greater extent. (wikipedia.org)
8) What is the most sensitive laboratory diagnostic tests for Chlamydia pneumoniae ? (medicalbiochemist.com)
C. trachomatis and C. pneumoniae, have an immense impact on public health in the US and globally. (ku.edu)

C. trachomatis are bacteria in the genus Chlamydia, a group of obligate intracellular parasites of eukaryotic cells. (wikipedia.org)
Zweytick D , Athenstaedt K , Daum G . Intracellular lipid particles of eukaryotic cells. (microbiologyresearch.org)
C. trachomatis is an obligate, aerobic, intracellular parasite of eukaryotic cells. (virtualpsychcentre.com)
Infectious chlamydial particles (known as elementary bodies (EBs)) attach to, and internalize within, host eukaryotic cells. (biomedcentral.com)

About 70-90% of women with endocervical infections due to C. trachomatis are asymptomatic and thereby do not seek medical treatment and become a reservoir for transmission. (unc.edu.ar)
To a lesser extent, genital infections due to C. trachomatis in males may also be asymptomatic and chronic, which also contributes to spreading and sometimes lead to complications like epididymitis and prostatitis. (unc.edu.ar)

Chlamydia trachomatis is an obligate intracellular human pathogen that exhibits stage-specific gene transcription throughout a biphasic developmental cycle. (plos.org)
Thus, it is thought that the success of C . trachomatis as a human pathogen may lie in its ability to survive these immunological stress situations by slowing growth and development until conditions in the cell have improved. (plos.org)
Chlamydia trachomatis is a ubiquitous human pathogen that is responsible for the most prevalent bacterial sexually transmitted diseases (STDs) worldwide ( 1 ). (cdc.gov)
18) A vaginal swab specimen was taken from the 23 year old patient with symptoms of painful urination, a laboratory diagnosis of the chlamydial pathogen was performed. (medicalbiochemist.com)
In our laboratory, we are interested in the study of cell and molecular events associated to virulence, pathogenesis and host-pathogen interactions of C. trachomatis , which is an obligate intracellular bacterium with a high impact in public health globally. (unc.edu.ar)
These results reveal a novel immune evasion strategy used by the intracellular bacterial pathogen chlamydia that improves our understanding of the molecular basis of pathogenesis. (silverchair.com)
Chlamydia is an obligate intracellular bacterial pathogen ( 19 ) and the causative agent of many important human diseases ( 20 , 21 ). (silverchair.com)

Three species of Chlamydia cause human disease, including sexually transmitted infections and respiratory infections. (msdmanuals.com)
Chlamydia infections of the rectum may lead to proctitis, rectal pain, discharge and/or bleeding (2). (genetrack.ca)
There are many similarities between the infections caused by N. gonorrhoeae and Chlamydia trachomatis (CT) . (pediagenosis.com)
Chlamydia and LGV are quite different infections. (diseasesdic.com)
The bacteria enter through a moist mucosal surface - most commonly, the rectum or vagina, but infections in the penis or mouth are also possible. (diseasesdic.com)
2) Which of the following is a common specimen used for the diagnosis of sexually transmitted chlamydial infections that occur in both men and women? (medicalbiochemist.com)
3) What type of methods are important laboratory approaches for the diagnosis of genital Chlamydia spp infections? (medicalbiochemist.com)
Bacterial infections include chlamydia, gonorrhea, and syphilis. (virtualpsychcentre.com)
Development of a vaccine has been hindered by the lack of vertebrate animal models that more closely mimics human immune responses as well as characterization of the correlates for immunity to human Chlamydia infections. (ku.edu)
C. trachomatis is the main bacterial cause of sexually transmitted infections and of infectious blindness worldwide. (unc.edu.ar)
The ability of this bacterium to cause recurrent and persistent infections results in serious complications such as pelvic inflammatory disease, ectopic pregnancy, abortion and infertility, mainly in young women. (unc.edu.ar)
Chlamydial persistence has been linked to the capacity of causing chronic/ recurrent infections both in women and men and with increased antimicrobial resistance, making this a highly relevant phenomenon in chlamydial pathogenesis. (unc.edu.ar)
One hundred thirty million Chlamydia trachomatis infections are reported worldwide each year. (analesdepediatria.org)

As an obligate intracellular bacterium, it has a distinctive biphasic developmental cycle ( 2 ). (cdc.gov)
Chlamydiae are obligate intracellular bacteria with a biphasic developmental cycle that involves cell types adapted for extracellular survival and intracellular multiplication. (nih.gov)
Chlamydiae undergo their developmental cycle entirely within a parasitophorous vacuole, termed an inclusion, that is isolated from established routes of endocytic vesicle trafficking. (nih.gov)
Chlamydia (klah-MID-e-a) are obligate intracellular bacteria that are propagated and maintained through a phylum defining bi-phasic developmental cycle. (ku.edu)
The Chlamydia developmental cycle is fascinating and there are many fundamental aspects that are still poorly understood. (ku.edu)
While the developmental cycle is intriguing, it is also essential for Chlamydia to cause disease in humans. (ku.edu)
The chlamydial developmental cycle involves the alternation between the metabolically inert elementary body (EB) and the replicating reticulate body (RB). (biomedcentral.com)
The model uses knowledge and data of the biological system wherever available and simulates the chlamydial developmental cycle under the assumptions of the hypothesis in order to predict various outcomes and implications under a number of scenarios. (biomedcentral.com)

C. trachomatis propagates through a biphasic cycle involving the elementary body (EB) and the reticulate body (RB). (unc.edu.ar)

Between 20 and 30% of heterosexual men with symptomatic gonococcal urethritis are simultaneously infected with Chlamydia trachomatis . (pediagenosis.com)
10) Name the organism given below which is frequently associated with urethritis apart from Chlamydia trachomatis ? (medicalbiochemist.com)
The most common cause of nongonococcal urethritis (NGU) is Chlamydia trachomatis (15-40% of cases), followed by Mycoplasma genitalium (15-20% of cases). (medscape.com)
Neisseria gonorrhoeae, the cause of gonococcal urethritis, is a gram-negative intracellular diplococcus. (medscape.com)

Gonococci enter the body by attaching to nonciliated columnar mucosal epithelial cells using specialized surface structures on the bacteria known as pili (Fig. 46.1). (pediagenosis.com)
Chlamydiae access the body by invading the same epithelial cells of the endocervix, urethra, endometrium, fallopian tubes, rectum and conjunctivae that are host to the gonococcus. (pediagenosis.com)
Chlamydiae are small gram-negative obligate intracellular microorganisms that preferentially infect squamocolumnar epithelial cells. (virtualpsychcentre.com)

Rescreening for C trachomatis and N gonorrhoeae is recommended 3 months after treatment. (medscape.com)

Increasingly, isolates representing single clones are needed for in vitro and in vivo research, including genomic, murine, and translational studies, to advance our understanding of chlamydial pathogenesis. (cdc.gov)
Here we review biogenesis of lipid droplets as well as the role of lipid droplets in the pathogenesis of selected viruses, bacteria, protists and yeasts. (microbiologyresearch.org)
Besides persistence, we are also interested in studying other key aspects of C. trachomatis pathogenesis such as nutrient acquisition, immune evasion and Chlamydia -induced reprogramming of the host cell machinery during the infectious cycle. (unc.edu.ar)

Like other Chlamydia species, the C. trachomatis life cycle consists of two morphologically distinct life stages: elementary bodies and reticulate bodies. (wikipedia.org)
Like other Chlamydia species, C. trachomatis has a life cycle consisting of two morphologically distinct forms. (wikipedia.org)
C. trachomatis is thought to have diverged from other Chlamydia species around 6 million years ago. (wikipedia.org)
As the use of serological methods increases the window of detection, the goal of this study was to investigate if it is possible to develop a differentiating serological test for antibodies against Chlamydia species in chicken sera. (biomedcentral.com)
Nevertheless, results of the suspension array with field sera are supported by published data on the occurrence of C. gallinacea in Dutch layers, thereby demonstrating the proof of concept of multiplex serology for Chlamydial species in poultry. (biomedcentral.com)

All chlamydia, including those serovars causing LGV, are obligate intracellular microorganisms but LGV serovars are lymphotropic. (hopkinsguides.com)

LGV due to Chlamydia trachomatis L1, L2 and L3 serovars. (hopkinsguides.com)
LGV is distinct from other chlamydia serovars causing either common genital chlamydial disease (serovars D-K) or trachoma (serovars A-C). (hopkinsguides.com)

C. trachomatis exclusively infects humans. (wikipedia.org)
Infected birds shed the bacteria through feces and nasal discharges, and humans become infected from exposure to these materials. (cdc.gov)
Chlamydia trachomatis is the etiological agent of several significant diseases of humans, including trachoma, the leading cause of infectious blindness worldwide. (nih.gov)
The origins of both sexually transmitted and ocular C. trachomatis are unclear, but it seems likely that they evolved with humans and shared a common ancestor with environmental chlamydiae some 700 million years ago. (virtualpsychcentre.com)

Chlamydia trachomatis is a gram-negative bacterium that can replicate only within a host cell. (wikipedia.org)
R. rickettsii is a small, obligate, intracellular, Gram-negative organism maintained in its tick host through transovarial transmission. (nih.gov)
It is a Gram-negative bacteria and has a coccoid or rod shape. (virtualpsychcentre.com)
It has a cytoplasmic membrane and outer membrane similar to Gram-negative bacteria (thus, it being classified as Gram-negative) but, it lacks a peptidoglycan cell wall. (virtualpsychcentre.com)

The Host-Parasite Interactions Section studies the basic molecular and cellular biology of chlamydiae and other obligate intracellular parasites. (nih.gov)
Whereas the majority of intracellular parasites are thought to block maturation of the endocytic vesicle to a lysosome, chlamydiae rapidly dissociate themselves from this pathway and establish a functional interaction with an exocytic pathway that delivers sphingolipids and cholesterol from the Golgi apparatus to the plasma membrane. (nih.gov)

Because gonorrhea and chlamydia are reportable to the state health departments in the United States,[11] confirmatory diagnostic testing is recommended. (medscape.com)
Nucleic acid amplification testing of a first-catch urine specimen is the most sensitive test (in a male) for gonorrhea or chlamydia. (medscape.com)

C. trachomatis is the single most important infectious agent associated with blindness (trachoma), and it also affects the eyes in the form of inclusion conjunctivitis and is responsible for about 19% of adult cases of conjunctivitis. (wikipedia.org)
Trachoma Trachoma is a chronic conjunctivitis caused by Chlamydia trachomatis and is characterized by progressive exacerbations and remissions. (msdmanuals.com)
Sexually acquired chlamydial conjunctivitis can also occur in both males and females (3). (genetrack.ca)

These include global regulation of chlamydial gene expression via histone-like proteins, vesicular trafficking, cytoskeletal interactions, cell signaling, chlamydial modification of the inclusion membrane, and interactions mediated by Type III secreted protein effectors, which control entry and subsequent events. (nih.gov)
To enable differentiating serology, a bead-based Luminex suspension array was constructed, using peptides as antigens, derived from known immunoreactive Chlamydia proteins. (biomedcentral.com)
Additionally, we are interested in characterizing the proteome of persistent forms in order to identify chlamydial proteins that are differentially expressed during this state. (unc.edu.ar)

hence why prompt diagnosis and treatment of chlamydia is very important. (genetrack.ca)
The diagnosis of Chlamydia was made by plasmid detection with an in-house PCR assay, and genotypes were identified using a PCR-RFLP assay for the ompA gene. (analesdepediatria.org)

Lymphogranuloma venereum (LGV) is an uncommon sexually transmitted disease (STD) caused by Chlamydia trachomatis . (medscape.com)
Chlamydia is a common sexually transmitted disease. (virtualpsychcentre.com)
Chlamydia is the most common bacterial sexually transmitted disease in the country. (virtualpsychcentre.com)

Association between Chlamydia trachomatis genotypes and clinical features of the newborn. (analesdepediatria.org)

Chlamydia trachomatis causes both genital tract and ocular diseases. (ku.edu)

C. trachomatis also is the leading cause of preventable blindness (trachoma) worldwide. (ku.edu)

16) Which of the following syndrome is most commonly associated with complications of pelvic inflammatory disease caused by Chlamydia trachomatis ? (medicalbiochemist.com)

If not treated, chlamydia can lead to damage to the reproductive system. (virtualpsychcentre.com)

C. trachomatis is the most common infectious cause of blindness and the most common sexually transmitted bacterium. (wikipedia.org)

What are the characteristics of Chlamydia trachomatis? (virtualpsychcentre.com)

If during replication Chlamydia encounters stress factors, like those resulting from exposure to INF-gamma (a key cytokine in the immune response) or beta-lactam antibiotics, these bacteria enter in a viable/ non-culturable state which is also known as "persistent form" or "aberrant body", usually much bigger than the RBs. (unc.edu.ar)
If during replication Chlamydia encounters stressing conditions, like those resulting exposure to gamma-interferon (INFγ) or β-lactam antibiotics, RBs can reversibly differentiate into "persistent forms" or "aberrant bodies", which sometimes exhibit striking morphological differences like increased size and an irregular shape. (unc.edu.ar)

These serotypes are more virulent and invasive compared to other chlamydial serotypes. (medscape.com)

Interaction with this secretory pathway is thought to constitute a novel pathogenic mechanism whereby chlamydiae establish themselves in a site not destined to fuse with lysosomes. (nih.gov)
Understanding the initial events in chlamydial differentiation, including the transition in properties of the endocytic vesicle to one which intersects an exocytic pathway, remains a significant challenge in deciphering the pathogenic mechanisms of chlamydiae. (nih.gov)
This article provides an overview of the most important human pathogenic bacteria. (amboss.com)
The following table provides an overview of the nomenclature of important human pathogenic bacteria, according to their form and Gram staining properties. (amboss.com)

This mode of growth is known as persistence and how C . trachomatis senses stress and responds in this manner is an important area of research. (plos.org)
In this context, we are interested in studying the poorly characterized factors involved in chlamydial persistence. (unc.edu.ar)
In order to identify the chlamydial genes involved in persistence induced by INF-gamma or beta-lactam antibiotics we are using a genomics approach based on chemical mutagenesis and whole genome sequence analysis. (unc.edu.ar)

Within the inclusion, C. trachomatis transforms into a larger, more metabolically active form called the reticulate body. (wikipedia.org)
The reticulate body substantially modifies the inclusion, making it a more hospitable environment for rapid replication of the bacteria, which occurs over the following 30 to 72 hours. (wikipedia.org)
After directing entry into a eukaryotic cell, the EBs quickly modifies the early endosome into a Chlamydia specific vessicle termed an inclusion. (ku.edu)
We have proposed a hypothesis to explain key chlamydial developmental events whereby RBs are replicating strictly whilst in contact with the host cell membrane-derived inclusion via type three secretion (T3S) injectisomes. (biomedcentral.com)

What are the long-term complications of chlamydia? (genetrack.ca)

Inflammation associated with chlamydia increases the risk of ectopic pregnancy, which is when the fertilized egg implants and grows outside the main cavity of the uterus (14). (genetrack.ca)

Over the course of the C. trachomatis life cycle, the bacteria take on two distinct forms. (wikipedia.org)

Following endocytosis of the bacteria, vacuoles containing viable and replicating gonococci pass through the cell from the mucosal surface to the subepithelial membrane. (pediagenosis.com)

We therefore developed a novel method for estimating chlamydial incidence. (cdc.gov)

Chlamydial cells cannot carry out energy metabolism and they lack biosynthetic pathways. (wikipedia.org)
However, the IFN-γ-induced IFN regulatory factor-1 (IRF-1) and intercellular adhesion molecule 1 (ICAM-1) expression is not affected, suggesting that chlamydia may selectively target the IFN-γ signaling pathways required for MHC class II expression. (silverchair.com)

The bacteria are transmitted between cells and hosts as small, metabolically inert, Elementary Bodies (EB). (ku.edu)

A model is proposed where the relative levels of active antagonist (RsbV1) and switch-protein anti-sigma factor (RsbW) control the availability of σ 66 and subsequently act as a molecular 'throttle' for Chlamydia growth and development. (plos.org)

Anatomy3

Organisms12

Diseases16

Chemicals and Drugs4

Analytical, Diagnostic and Therapeutic Techniques and Equipment1

Psittaci14

Infection29

Pathogens11

Strains9

Pneumoniae3

Eukaryotic cells4

Asymptomatic2

Pathogen7

Infections13

Developmental cycle8

Biphasic1

Urethritis4

Epithelial cells3

Gonorrhoeae1

Pathogenesis3

Species5

Microorganisms1

Serovars2

Humans4

Gram-negative4

Parasites2

Gonorrhea2

Conjunctivitis3

Proteins3

Diagnosis2

Sexually transmi3

Clinical1

Ocular1

Trachoma1

Pelvic1

Reproductive1

Infectious1

Characteristics1

Persistent2

Serotypes1

Pathogenic4

Persistence3

Inclusion4

Complications1

Ectopic1

Distinct1

Mucosal1

Incidence1

Pathways2

Metabolically1

Molecular1