Obesity and metabolic syndrome chronic metabolic. Medical search. Frequent questions

To address variation between professional guidelines, the NHLBI, AHA, International Diabetes Foundation (IDF), and others have proposed a harmonized definition of metabolic syndrome. (medscape.com)
Obesity and diabetes are the main causes of chronic kidney disease (CKD) and end stage renal disease (ESRD). (researchsquare.com)
The objective of this study was to analyze the impact of obesity and diabetes on CKD and ESRD incidence and prevalence. (researchsquare.com)
Notably, the association of obesity and diabetes potentially increases the incidence and prevalence of CKD and ESRD. (researchsquare.com)
Results from the cohort, case-control and cross-sectional studies pointed out a positive association between obesity, diabetes and risks for renal disease outcomes. (researchsquare.com)
Taken together, obesity and diabetes are significantly associated with the increasing incidence and prevalence of CKD and ESRD. (researchsquare.com)
Previous reviews have discussed the relationship between obesity and ESRD or diabetes and ESRD separately. (researchsquare.com)
However, importantly, this review gives an insight on the association between obesity, diabetes and CKD/ ESRD. (researchsquare.com)
Obesity is well known for causing morbidity, mortality, disability and has been associated to an increasing number of cardiovascular and metabolic comorbidities, such as hypertension and diabetes mellitus (DM). (researchsquare.com)
Physical activity is essential for preventing and controlling risk factors and chronic diseases, such as diabetes, high blood pressure (HBP), cardiovascular disease (CVD), obesity, cancer, and depression (1). (cdc.gov)
Metabolic syndrome is a combination of conditions that include insulin resistance/Type II diabetes, HTN, hyperlipidemia, and obesity. (nursingcenter.com)
The primary risk factors of NASH include obesity (body mass index [BMI] >30), insulin resistance, Type II diabetes, "central adiposity" ( Paskos & Paletas, 2009 , para. (nursingcenter.com)
It may also decrease risk factors of metabolic syndrome, a cluster of conditions that raise the risk of heart disease, stroke, and diabetes. (medicalnewstoday.com)
Obesity, diabetes, and metabolic syndrome represent chronic diseases that affect life expectancy. (minervamedica.it)
Cardiovascular risk partly linked to therapies and genetic susceptibility and partly linked to the presence of obesity, diabetes and metabolic syndrome predispose childhood cancer survivors to heart failure, coronary artery disease, valvular disease, arrhythmia. (minervamedica.it)
We already know that the epidemic of obesity, insulin resistance, and diabetes is in large part due to the consumption of high fructose corn syrup in the American diet. (naturalnews.com)
Obesity and metabolic syndrome play a huge part in the epidemic of chronic inflammatory diseases including heart disease, cancer, and diabetes. (naturalnews.com)
This includes patients who are 50 years of age or older and/or have certain medical conditions such as chronic heart or lung disease, obesity, diabetes or a weakened immune response. (snohd.org)
The consequences are real: "Not only does metabolic syndrome increase your risk of heart disease by about twofold, it's a much stronger risk factor for diabetes too-anywhere between three to five times higher for those who have metabolic syndrome compared to those who don't. (oprah.com)
Metabolic syndrome--a combination of risk factors that may lead to high blood pressure, diabetes, heart disease, and stroke--is one of the results of the obesity epidemic. (sciencedaily.com)
Sugar-sweetened soft drinks have been shown to cause obesity, type 2 diabetes, dental decay and metabolic syndrome. (weeksmd.com)
Beyond etiology and severity of liver disease, traditional and metabolic risk factors, such as diabetes mellitus, older age, male gender and tobacco smoking, are not enough for HCC risk stratification for surveillance efficacy and effectiveness in NAFLD. (thieme-connect.com)
Metabolic syndrome is a group of very common obesity-related disorders that can lead to type-2 diabetes, cardiovascular and/or liver diseases. (eurekalert.org)
Additionally, abdominal obesity, prevalent in the U.S. workforce, usually causes restrictive pattern of impairment, and increased risk of metabolic syndrome and cardiovascular disease and diabetes. (cdc.gov)
Obesity can induce type 2 diabetes mellitus, dyslipidemia, cardiovascular disease and other chronic disorders with high social and health costs. (benthamscience.com)
Obesity was firstly described in 2000 as a cardiometabolic disease, even before Metabolic Syndrome, type 2 diabetes mellitus and coronary disease were considered as such. (benthamscience.com)
metabolic syndrome, type 2 diabetes, cardiovascular lesions and malignancies. (benthamscience.com)
As a consequence, there has also been a marked increase in the prevalence of type 2 diabetes all over the world and this chronic metabolic disease is now considered as a coronary heart disease risk equivalent. (researchgate.net)
Nontransmissible chronic diseases, such as diabetes mellitus (DM) and nephropathy, affect a significant portion of the population, often treated due to injuries that require healing and regeneration. (scielo.br)
In addition to accounting for the presence or absence of preexisting coronary heart disease or its equivalents (e.g., diabetes, chronic kidney disease), cardiovascular risk can be further calculated with the Framingham risk score, which is based on age, sex, smoking history, and lipid and blood pressure levels. (aafp.org)
Diseases such as obesity, diabetes, and hypertension have been found to be closely associated with the incidence of NAFLD. (wjgnet.com)
Routine screening is not recommended for other groups of patients, such as those with obesity or diabetes mellitus. (scielo.br)
For those aged 20-39 years, it is reasonable to measure traditional risk factors every 4-6 years to identify major factors (e.g., tobacco, dyslipidemia, family history of premature ASCVD, chronic inflammatory diseases, hypertension, or type 2 diabetes mellitus [T2DM]) that provide rationale for optimizing lifestyle and tracking risk factor progression and need for treatment. (acc.org)
New Horizons: Epidemiology of Obesity, Diabetes Mellitus, and Cancer Prognosis. (medscape.com)
PD has been suggested as a possible risk factor for some of the components of MS, such as diabetes, obesity and dyslipidemia. (bvsalud.org)
Reference ranges of immunoglobulins may vary based on sex and factors such as alcohol use, smoking status, and chronic conditions (eg, diabetes/metabolic syndrome) (see Considerations). (medscape.com)
In recent years, HCC has also been associated with obesity, diabetes, and the metabolic syndrome. (medscape.com)

Metabolic syndrome (syndrome X, insulin resistance) is a multifactorial disease with multiple risk factors that arises from insulin resistance accompanying abnormal adipose deposition and function. (medscape.com)
Obesity causes the amount of cholesterol in bile to rise, in turn the formation of stone can occur Due to its association with insulin resistance, the risk of obesity increases with polycystic ovarian syndrome (PCOS). (wikipedia.org)
They come together as a symbiotic relationship, such as obesity coupled with insulin resistance, and with these come HTN and hyperlipidemia. (nursingcenter.com)
Perhaps, the strongest risk factors for the development of NASH syndrome are obesity and insulin resistance. (nursingcenter.com)
It improves insulin sensitivity, reduces cholesterol and triglyceride production, and suppresses chronic inflammation. (wellnessresources.com)
CR favorably impacted metabolic profiles of obesity (i.e., lower body weight, plasma glucose and plasma insulin) in obese mice, but the addition of Cur and/or Pip into the CR diet resulted in no further measurable benefit on total body weight. (springer.com)
This study is the first to document insulin resistance and metabolic syndrome effects in the brain. (naturalnews.com)
Agrawal R and Gomez-Pinilla F. 'Metabolic syndrome' in the brain: deficiency in omega-3 fatty acid exacerbates dysfunctions in insulin receptor signalling and cognition. (naturalnews.com)
In contrast, in mice with normal immune systems, emulsifiers induced low-grade or mild intestinal inflammation and metabolic syndrome, characterized by increased levels of food consumption, obesity, hyperglycemia and insulin resistance. (eurekalert.org)
Probably even more important, it seems to be a good predictor of insulin resistance or Metabolic Syndrome, and has been used by some (importantly Gerald Reaven) as a surrogate marker for insulin resistance. (ecopolitan.com)
In obese subjects, adipokines and miokines interact to promote reticulum stress, insulin resistance, metabolic inflexibility and endothelial dysfunction. (benthamscience.com)
However, even in the absence of the hyperglycaemic state which characterizes type 2 diabetic patients, non diabetic individuals with a specific form of obesity, named abdominal obesity, often show clustering metabolic abnormalities which include high triglyceride levels, increased apolipoprotein B, small dense low density lipoproteins and decreased high density lipoproteins-cholesterol levels, a hyperinsulinemic-insulin resistant state, alterations in coagulation factors as well as an inflammatory profile. (researchgate.net)
Evidence suggests that obesity and insulin resistance are the major factors that contribute to the development of NAFLD. (wjgnet.com)
A new study finds that adipocyte SLC7A10 impairments may impact lipid accumulation during insulin resistance in patients with obesity. (medscape.com)
Recent studies suggest an association between vitamin D status, metabolic syndrome, insulin resistance, and obesity among Canadians (12,13). (cdc.gov)

The clinical manifestations of this syndrome may include hypertension , hyperglycemia, hypertriglyceridemia, reduced high-density lipoprotein cholesterol (HDL-C), and abdominal obesity . (medscape.com)
Risk estimates indicate that at least two-thirds of people with hypertension can be directly attributed to obesity. (wikipedia.org)
The association between obesity and hypertension has been found in animal and clinical studies, which have suggested that there are multiple potential mechanisms for obesity-induced hypertension. (wikipedia.org)
As of 2007, it was unclear whether there is an association between hypertension and obesity in children, but there is little direct evidence that blood pressure has increased despite increases in pediatric overweight. (wikipedia.org)
He was a 51-year-old man with chronic obstructive pulmonary disease (COPD), hypertension and idiopathic gastroparesis. (weeksmd.com)
Obesity has definitely become a growing problem, but a lot of anti-obesity educations, with fen-peen as the best example, have proven to have very damaging side-effects like lung hypertension and heart valve condition (Fen Peen, 2010). (directcurrentmusic.com)
It is suggested that until the epidemic progression of obesity is stopped and obesity prevented or at least properly managed, cardiologists will be confronted to an evolving contribution of risk factors where smoking, hypercholesterolemia and hypertension may be relatively less prevalent but at the expense of a much greater contribution of abdominal obesity and related features of the metabolic syndrome. (researchgate.net)

Previous research shows that in the past 30 years, artificial sweeteners and diet soda intake have increased, yet the prevalence of obesity has also seen a dramatic increase in the same time period. (sciencedaily.com)
2 ] [ 5 ] [ 6 ] In parallel with the rising prevalence of obesity and metabolic syndrome, nonalcoholic fatty liver disease (NAFLD) has emerged as the leading cause of HCC and is anticipated to result in up to 135,000 HCC cases in the United States between 2015 and 2030. (thieme-connect.com)
Blue-collar workers have the highest prevalence of chronic obstructive pulmonary disease (COPD) in the country. (cdc.gov)
Epidemiological studies suggest that the prevalence and severity of obesity have increased to epidemic proportions worldwide, making it a global public health problem. (molvis.org)
The alarming increase in the prevalence of obesity or MetS is likely to further exacerbate the risk for ophthalmic abnormalities associated with obesity. (molvis.org)
Obesity is a chronic disease with high prevalence and associated comorbidities, making it a growing global concern. (mdpi.com)
Available evidence clearly indicates a rapid progression in the prevalence of obesity worldwide. (researchgate.net)
Since 1975, the prevalence of obesity has tripled . (medscape.com)
The prevalence of Chronic Noncommunicable Disease (CND) are rocketting over the world, including in young adults. (bvsalud.org)
Metabolic syndrome presented a prevalence of 24.0%, with a higher frequency in females (33.8%) (p=0.007). (bvsalud.org)
Concerning chronic kidney disease, a prevalence of 12.1% was observed in both sexes. (bvsalud.org)
Problem: Over 290 million people worldwide suffer from chronic hepatitis B (CHB), with the highest prevalence in the Pacific islands. (who.int)
The prevalence of noncommunicable dis- lance system for risk behaviours and risk eases (NCDs) is rising rapidly and they are factors for chronic diseases. (who.int)

For example, sleep-related breathing disorders, such as obstructive sleep apnea, are becoming increasingly relevant and novel risk factors for metabolic syndrome. (medscape.com)
We then reviewed whether the reported changes in gut bacterial members found to be established by complex carbohydrates would benefit or harm the cardiometabolic and immunological health of the host taking into account the alterations in the microbiome composition and abundance known to be associated with obesity and its associated disorders. (frontiersin.org)
These findings expand the concept of metabolic syndrome affecting the brain and provide the mechanistic evidence of how dietary habits can interact to regulate brain functions, which can further alter lifelong susceptibility to the metabolic disorders. (naturalnews.com)
[ 3-5 ] Major risk factors for HCC include chronic infections with hepatitis B and hepatitis C viruses, excessive alcohol consumption, certain rare metabolic disorders, and consumption of food contaminated with aflatoxin. (medscape.com)

Abdominal obesity is associated with cardiovascular diseases including angina and myocardial infarction. (wikipedia.org)
No studies to date have evaluated the association between feeling comfortable visiting a park and the risk of chronic diseases such as HBP. (cdc.gov)
Dietary supplementation with complex carbohydrates is known to alter the composition of gut microbiota, and optimal implementation of the use of these so called "prebiotics" could be of great potential in prevention and possibly treatment of obesity and associated cardiometabolic and inflammatory diseases via changes in the gut microbiota. (frontiersin.org)
Alterations in gut microbiota composition are associated with metabolic syndrome and chronic inflammatory diseases such as inflammatory bowel disease. (nature.com)
Thus, administration of flagellin, and perhaps other pathobiont antigens, may confer some protection against chronic inflammatory diseases. (nature.com)
An array of chronic inflammatory diseases are associated with dysbiosis in the intestinal microbiota and a breakdown in the normally mutually beneficial host-microbiota relationship. (nature.com)
Such diseases include inflammatory bowel diseases (IBD) and diseases characterized by low-grade inflammation, such as metabolic syndrome. (nature.com)
Through studies, individual counseling, or classes, we teach individuals successful ways to make healthy dietary changes into long-term lifestyle changes to prevent and treat chronic diseases and conditions. (umassmed.edu)
Findings raise concerns about the safety of chronic diet soda consumption, which may increase belly fat and contribute to greater risk of metabolic syndrome and cardiovascular diseases. (sciencedaily.com)
This is a systematic review and meta-analysis to quantify the efficacy and safety of HIIT compared to MICT in individuals with chronic cardiometabolic lifestyle diseases. (scienceopen.com)
HIIT significantly increases CRF by almost double that of MICT in patients with lifestyle-induced chronic diseases. (scienceopen.com)
If similar results are obtained, it would indicate a role for this class of food additive in driving the epidemic of obesity, its inter-related consequences and a range of diseases associated with chronic gut inflammation. (eurekalert.org)
Metabolic syndrome (MetS) is associated with several degenerative diseases, including retinal degeneration. (molvis.org)

Metabolic syndrome linked to abdominal obesity is also predictive of recurrent coronary events both in post-myocardial infarction patients and among coronary artery disease men who underwent a revascularization procedures. (researchgate.net)

Increasing diet soda intake is directly linked to greater abdominal obesity in adults 65 years of age and older. (sciencedaily.com)
A new study published in the Journal of the American Geriatrics Society shows that increasing diet soda intake is directly linked to greater abdominal obesity in adults 65 years of age and older. (sciencedaily.com)
The SALSA study shows that increasing diet soda intake was associated with escalating abdominal obesity, which may increase cardiometabolic risk in older adults," Fowler concludes. (sciencedaily.com)
This agglomeration of abnormalities has been referred to as the metabolic syndrome which can be identified by the presence of three of the five following variables: abdominal obesity, elevated triglyceride concentrations, low HDL-cholesterol levels, increased blood pressure and elevated fasting glucose. (researchgate.net)

Obese (OB) patients are at increased risk of chronic kidney disease, but it is still unclear whether this can be attributed to obesity per se or to the associated metabolic derangements. (karger.com)
The aim of this study was to evaluate the relative impact of obesity and metabolic syndrome (MS) on kidney disease. (karger.com)
This large cross-sectional study suggests that MS and not obesity is associated with kidney damage and that the OB+ MS− phenotype does not seem to carry an increased risk of kidney disease. (karger.com)
Chronic kidney disease (CKD) is a common, progressive condition with a clinical spectrum ranging from mild disease to an end-stage, debilitating state [ 1 ]. (karger.com)
They appear also to increase the risk for osteoporosis, gout, gastroesophageal reflux disease, hypovitaminosis C, albuminuria and chronic kidney disease (CKD). (weeksmd.com)
In underdeveloped countries, diabetic nephropathy, the main glomerular disease, is recognized as one of the main causes for the appearance and evolution of chronic kidney disease (CKD). (scielo.br)

Some obesity-associated medical conditions may be the result of stress caused by medical discrimination against people who are obese, rather than the direct effects of obesity, and some may be exacerbated by the relatively poor healthcare received by people who are obese. (wikipedia.org)
Because of the social stigma of obesity, people who are obese may receive poorer healthcare than people within the normal BMI weight range, potentially contributing to the relationship between obesity and poor health outcomes. (wikipedia.org)
In the present study, we further investigated whether Cur and/or Pip could improve metabolic profiles in obese mice subjected to CR on a HFD. (springer.com)

Dietary bioactive compounds capable of improving metabolic profiles would be of great value, especially for overweight individuals undergoing a caloric restriction (CR) regimen. (springer.com)
Studies showed that 65% of the world's population live in countries where overweight and obesity kills more people than underweight (World Health Organization, 2012). (directcurrentmusic.com)

Incidence of IBD and metabolic syndrome has been markedly increasing since the mid-20th century. (eurekalert.org)
Non-alcoholic fatty liver disease (NAFLD) has grown in incidence to become the most common chronic liver disease worldwide [1] and is projected to surpass alcoholic liver disease as the leading cause of liver transplantation in the United States by 2030 [2]. (termedia.pl)

A number of potential implications for clinical practice are derived from the cardiometabolic state underlying obesity and its comorbidities. (benthamscience.com)

Obesity is a multifactorial disease that is currently developing a threatening tendency towards becoming the main cause of chronic disease in the world. (benthamscience.com)
Obesity is a complex, multifactorial disease and a global pandemic . (medscape.com)

The 2018 Southeastern Pennsylvania Household Health Survey of (CVD), obesity, cancer, and depression (1). (cdc.gov)
Fortunately, the five-years survival rate has progressively improved reaching 80% thanks to the continuing improvement of therapeutic protocols but most of these cancer survivors will have at least one chronic health condition by 40 years of age. (minervamedica.it)
Hence the cardio- metabolic risk of childhood cancer survivors can have a significant impact on their lives, families, and on society at-large. (minervamedica.it)
Therefore, it is very important to know the risk factors that predispose to the development of cardio-metabolic pathologies in childhood cancer survivors, the possible primary and secondary prevention strategies, the methods of surveillance and the therapeutic approaches. (minervamedica.it)

However, overall obesity (as measured by BMI) may lead to false diagnoses of myocardial infarction and may decrease mortality after acute myocardial infarction. (wikipedia.org)
The focus is primary prevention in adults to reduce the risk of ASCVD (acute coronary syndromes, myocardial infarction, stable or unstable angina, arterial revascularization, stroke/transient ischemic attack, peripheral arterial disease), as well as heart failure and atrial fibrillation. (acc.org)

www.cdc.gov/pcd/issues/2023/23_0098.htm Preventing Chronic Disease. (cdc.gov)

Mortality from cardiovascular disease has decreased despite increases in obesity, and at least one clinical trial was stopped early because the weight loss intervention being tested did not reduce cardiovascular disease. (wikipedia.org)
In 2008, European guidelines concluded that 35% of ischemic heart disease among adults in Europe is due to obesity. (wikipedia.org)
This includes obesity-related factors that increase the likelihood of cardiovascular disease. (medicalnewstoday.com)
So, you're dealing with obesity on one end, and estrogen decline on the other, at an age when people start developing heart disease," says Pradhan. (oprah.com)
The burden of metabolic syndrome and cardiovascular disease, along with healthcare costs, is great in the ever-increasing senior population. (sciencedaily.com)
The included studies were required to have a population sample of chronic disease, where poor lifestyle is considered as a main contributor to the disease. (scienceopen.com)
The burden for hepatocellular carcinoma (HCC) attributed to nonalcoholic fatty liver disease (NAFLD) continues to grow in parallel with rising global trends in obesity. (thieme-connect.com)
The quality of current evidence for HCC surveillance in all patients with chronic liver disease is poor, and even lower in those with NAFLD. (thieme-connect.com)
Most HCCs develop in the setting of cirrhosis from chronic liver disease, with hepatitis B virus (HBV) and hepatitis C virus (HCV) as the predominant risk factors worldwide. (thieme-connect.com)
ATLANTA--Emulsifiers, which are added to most processed foods to aid texture and extend shelf life, can alter the gut microbiota composition and localization to induce intestinal inflammation that promotes the development of inflammatory bowel disease and metabolic syndrome, new research shows. (eurekalert.org)
While mortality rates for most chronic illnesses (heart disease, malignancy, stroke) have declined in the U.S., mortality from chronic obstructive pulmonary disease (COPD) has increased over the past 3 decades. (cdc.gov)
Clinicians should refer patients with chronic HCV and decompensated liver disease and patients who are pre- or post-liver transplant to a liver disease specialist. (hivguidelines.org)
Standard treatments remain ineffectual and the disease often runs a chronic relapsing course associated with significant psychosocial trauma for its sufferers. (cassiopaea.org)
A 19-year-old female with an 8-year history of progressively debilitating cicatricial HS disease presented with obesity, profound anemia, leukocytosis, increased platelet count, hypoalbuminemia, and elevated liver enzymes. (cassiopaea.org)
Cushing's disease (CD) is a rare clinical condition that is due to ACTH-producing pituitary adenoma, and it is the most common etiology of endogenous Cushing's syndrome after 6 yrs of age (~70%) ( 2 2. (scielo.br)
Other less common etiologies of endogenous Cushing's syndrome include ectopic ACTH secretion (EAS ~10%), adrenal adenomas and carcinomas and, more rarely, adrenal primary macronodular adrenal hyperplasia (PMAH) or primary pigmented nodular adrenal disease (PPNAD) ( Table 1 ). (scielo.br)
Cushing disease is Cushing syndrome that results from excess pituitary production of adrenocorticotropic hormone (ACTH) secondary to a pituitary adenoma. (msdmanuals.com)
Whereas the term Cushing syndrome denotes the clinical picture resulting from corticosteroid excess from any cause, Cushing disease refers to hyperfunction of the adrenal cortex due to pituitary ACTH excess. (msdmanuals.com)
HIV infection, chronic inflammatory or autoimmune disease, and low socioeconomic levels). (acc.org)
Introduction: Metabolic syndrome (MS) is a complex pathology that combines several risk factors for cardiovascular disease. (bvsalud.org)
Periodontal disease (PD) is a chronic infection that produces a local and systemic inflammatory response. (bvsalud.org)
Objective: The aim of this study was to review the literature about the possible association between periodontal disease and metabolic syndrome and to identify the components of this syndrome that may contribute to this association. (bvsalud.org)
Background Nonsteroidal anti-inflammatory drugs (NSAIDs) have been shown to reduce chronic inflammation and risk of many cancers, but their effect on risk of hepatocellular carcinoma (HCC) and death due to chronic liver disease (CLD) has not been investigated. (medscape.com)
Almost all HCCs occur in persons with preexisting chronic liver disease (CLD). (medscape.com)
Vitamin D may modulate various metabolic processes and may influence cardiometabolic disease risk in Canadians. (cdc.gov)

Post-mortem analyses of coronary arteries have indicated that obesity (associated with a high accumulation of abdominal fat measured at autopsy) was predictive of earlier and greater extent of large vessels atherosclerosis as well as increase of coronary fatty streaks. (researchgate.net)

Objectives Obesity is associated with chronic inflammation, which may impact recovery from mild traumatic brain injury (mTBI). (bmj.com)
Obesity and mild traumatic brain injury (mTBI) are associated with inflammation, but little is known about whether obesity moderates the relationship between mTBI and inflammatory response. (bmj.com)
Curcumin (Cur), a possible anti-obesity compound, and piperine (Pip), a plausible enhancer of Cur's bioavailability and efficacy, may be candidate agents for controlling body fat, metabolism and low grade inflammation. (springer.com)
Here, we set out to investigate whether elicitation of mucosal anti-flagellin antibodies by direct administration of purified flagellin might serve as a general vaccine against subsequent development of chronic gut inflammation. (nature.com)
Hence, we hypothesize that boosting levels of mucosal flagellin-specific IgA might help keep flagellated bacteria in check and, consequently protect against development of chronic gut inflammation. (nature.com)
Transplant of microbiota from emulsifiers-treated mice to germ-free mice was sufficient to transfer some parameters of low-grade inflammation and metabolic syndrome, indicating a central role for the microbiota in mediating the adverse effect of emulsifiers. (eurekalert.org)
NAD has been shown to positively affect both pro and anti-inflammatory cytokines, which helps improve immune cell regulation and helps decrease systemic and chronic inflammation. (holtorfmed.com)
[ 2 ] Chronic hepatic inflammation, secondary to CLD, represents an early stage in the carcinogenesis process. (medscape.com)
In general, chronic inflammation is associated with persistent cell damage and consecutive regeneration, potentially leading to changes such as fibrosis and cirrhosis and eventual hepatocellular carcinoma. (medscape.com)

In an effort to combat obesity, many adults try to reduce sugar intake by turning to nonnutritive or artificial sweeteners, such as aspartame, saccharin, or sucralose. (sciencedaily.com)

Both NAFLD and its progression into NASH are seen almost simultaneously, with at least some of the components of metabolic syndrome. (nursingcenter.com)
In the literature, there is a link that NAFLD is the hepatic component of the metabolic syndrome diagnosis ( Takahashi & Fukosato, 2014 ). (nursingcenter.com)

The first step in the therapeutic strategy against obesity should be the correct diagnosis of its causes and the promotion of lifestyle changes including physical exercise and a healthy diet. (benthamscience.com)
Is metabolic and bariatric surgery a safe and effective therapeutic option for adolescents with severe obesity? (medscape.com)

Clinicians should assess all patients with a confirmed diagnosis of chronic HCV infection, defined as a positive HCV surface antibody test result and detectable HCV RNA, for treatment. (hivguidelines.org)
Magnetic resonance imaging (MRI) of the pituitary, the corticotropin-releasing hormone (CRH) test and the high-dose dexamethasone suppression test are the main tests for the differential diagnosis of ACTH-dependent Cushing's syndrome. (scielo.br)
Newell-Price J, Trainer P, Besser M, Grossman A. The diagnosis and differential diagnosis of Cushing's syndrome and pseudo-Cushing's states. (scielo.br)
Beauregard C, Dickstein G, Lacroix A. Classic and recent etiologies of Cushing's syndrome: diagnosis and therapy. (scielo.br)

Prev Chronic Dis 2023;20:230098. (cdc.gov)
Recommendations From the 2023 International Evidence-based Guideline for the Assessment and Management of Polycystic Ovary Syndrome. (medscape.com)

Future research should take into account the different causes of obesity and its adverse health conditions, which in turn have drastic effects on the microbiome balance. (frontiersin.org)
Include questions to exclude secondary causes of obesity, some of which are rare. (medscape.com)
Secondary causes of obesity. (medscape.com)

Studies comparing ethnically similar populations exposed to different dietary environments have suggested that westernized diets are strongly associated with a higher risk of developing metabolic syndrome. (medscape.com)
Obesity is a risk factor for many chronic physical and mental illnesses. (wikipedia.org)
Obesity increases one's risk of venous thromboembolism by approximately 2.3 fold. (wikipedia.org)
A review in 2013 came to the result that obesity increases the risk of oligospermia and azoospermia in males, with an of odds ratio 1.3. (wikipedia.org)
This group tends to develop the other criteria of metabolic syndrome and run a much greater risk of developing NASH. (nursingcenter.com)
For many patients the benefit of treatment will outweigh the risk of drug side effects, or any risks associated with short-term holding of chronic medications that might interact with COVID-19 therapies. (snohd.org)
COVID-19 continues to cause 2,000 to 3,000 deaths per week in the U.S. High risk patients include those who are moderately to severely immune compromised or pregnant regardless of age, those 65 years or older, and those 50 years or older who have chronic health conditions. (snohd.org)
Here's how to find out if you have metabolic syndrome, and what to do to lower your risk. (oprah.com)
As estrogen levels decline, women are more likely to develop dangerous visceral (belly) fat, which increases the waistline and, as a result, spikes the risk of metabolic syndrome. (oprah.com)
It might seem obvious, but the best ways to reduce your risk of developing metabolic syndrome are to exercise more and to eat more healthfully . (oprah.com)
Sleep deprivation has been associated with alterations of innate and adaptive immune parameters, leading to a chronic inflammatory state and an increased risk for infectious/inflammatory pathologies. (worldhealth.net)

Prev Chronic Dis. (cdc.gov)

Atta-ur-Rahman, M. Iqbal Choudhary , " Anti-Obesity Drug Discovery and Development ", Bentham Science Publishers (2014). (benthamscience.com)
While awaiting the release of new drugs, topiramate, alone or combined with phentermine, has been proposed as a novel anti-obesity drug, showing relevant effects not only on weight loss but also on cardiometabolic alterations and biomarkers, even though new studies should clarify the mechanisms of these findings. (benthamscience.com)
With these information, the researchers hope that snow peas would prove to have significant anti-obesity effects. (directcurrentmusic.com)
Saccharin's pod extract as an anti-obesity agent on male albino mice. (directcurrentmusic.com)
2. Determine the percent anti- obesity activity of the test plant extract based on weight loss. (directcurrentmusic.com)
Significance of the Study If proven effective, the research study can serve as one of the basis for future searches, since not much anti-obesity agents were studied by the students of the Department of Pharmacy of the University of San Carols, Zebu City. (directcurrentmusic.com)

Percent body fat, plasma inflammatory markers associated with obesity (interferon (IFN)-γ, interleukin (IL)-10, IL-12 p70, IL-1β, IL-6 and KC/GRO), plasma Cur metabolites and liver telomere length were measured. (springer.com)
We studied its effects and mechanism of action on a rat model of non-alcoholic fatty liver with metabolic syndrome. (lidsen.com)
We found that YNCRG can reduce the accumulation of lipids in the liver of rats with metabolic syndrome, probably by affecting lipid metabolism and the signaling pathway associated with inflammatory reactions. (lidsen.com)

It is defined by the presence of visceral obesity, elevated triglycerides, decreased HDL, elevated blood pressure and blood glucose. (bvsalud.org)

Such changes in bacteria triggered chronic colitis in mice genetically prone to this disorder, due to abnormal immune systems. (eurekalert.org)
Childhood obesity has wide-ranging adverse effects on immune status, including an impact on responses to vaccination and infection. (worldhealth.net)
The downstream benefits of metabolic health include good mental and immune health. (worldhealth.net)

In the clinical examination, measure anthropometric parameters and perform the standard, detailed examination required in evaluating patients with any chronic, multisystem disorder, such as obesity. (medscape.com)

Sun B, Kudo M, Hayashi M, Qin LL, Wu LL, Liu TH, Gao M. YNCRG Alleviated Hepatic Steatosis in Metabolic Syndrome Model Rats by Improving Lipid Metabolism and Chronic Inflammatory Reaction. (lidsen.com)

We show, in mice, that repeated injection of flagellin elicits increases in fecal anti-flagellin IgA and alterations in microbiota composition, reduces fecal flagellin concentration, prevents microbiota encroachment, protects against IL-10 deficiency-induced colitis, and ameliorates diet-induced obesity. (nature.com)
Herein, we describe that repeated systemic administration of purified flagellin elicits a robust anti-flagellin fecal IgA response that serves to reshape microbiota composition, reduces flagellin expression, and protects against experimental colitis and metabolic syndrome. (nature.com)
Gut microbiota are disturbed in IBD and metabolic syndrome. (eurekalert.org)

High rates of obesity, metabolic syndrome, and co-infection with hepatitis B and hepatitis D in Kiribati make treatment less effective. (who.int)

Metformin and combined oral contraceptive pills in the management of polycystic ovary syndrome: a systematic review and meta-analysis. (medscape.com)

Cushing syndrome is a constellation of clinical abnormalities caused by chronic high blood levels of cortisol or related corticosteroids. (msdmanuals.com)

Metabolic syndrome is a precursor to a lot of bad outcomes," says Pradhan. (oprah.com)

Obesity and metabolic syndrome are being increasingly implicated and associated with younger ages and greater metabolic severity. (cassiopaea.org)

Screening for hypercortisolism is recommended for patients who present multiple and progressive clinical signs and symptoms, especially those who are considered to be more specific to Cushing's syndrome, abnormal findings relative to age ( e.g. , spinal osteoporosis and high blood pressure in young patients), weight gain associated with reduced growth rate in the pediatric population and for those with adrenal incidentalomas. (scielo.br)
In this patient with Cushing syndrome, findings shown include facial rounding, plethora of the cheeks, supraclavicular fat, and striae. (msdmanuals.com)

47 eight-week-old male C57BL/6 mice were fed a high fat diet (HFD) for 23 weeks to induce obesity. (springer.com)

Treatment of associated obstructive sleep apnea may also play a significant role in the management of metabolic syndrome. (medscape.com)

Combination of Cur and Pip has potential to enhance CR effects for the prevention of metabolic syndrome. (springer.com)

In the cases they describe, chronic consumption of 3-10 l of sugar-sweetened cola per day led to severe hypokalaemia, hypokalaemic myopathy, and in some cases, hypokalaemic paralysis. (weeksmd.com)

Renowned pediatric neuroendocrinologist with decades of experience treating childhood obesity, Robert Lustig, MD, brought his expertise in pediatric metabolic health to the stage. (worldhealth.net)
During his session "Helping Kids Thrive In A Metabolical World," Dr. Lustig explored metabolic syndrome as a primary threat to population health, the impact of poor metabolic health on pediatric immunity and development, and the paramount role of proper nutrition. (worldhealth.net)

Obesity is a multifactorial, highly complex medical condition involving abnormal or excessive body fat accumulation that can cause health impairment. (molvis.org)
The possibility of bingeing, purging, lack of satiety, food-seeking behavior, night-eating syndrome, and other abnormal feeding habits must be identified because management of these habits is crucial to the success of any weight-management program. (medscape.com)

About 90 percent of people with depression have sleep complaints such as insomnia, hypersomnia, sleep disordered breathing, or restless leg syndrome. (healthline.com)
A lack of this cellular fuel is common in conditions such as chronic fatigue syndrome (CFS), depression, anxiety, and even addiction issues. (holtorfmed.com)

A recent study found that people who felt stigmatized about their size had six times greater odds of having high triglycerides and were three times more likely to develop metabolic syndrome . (oprah.com)

Brand new research published in the last few weeks reveals important information for people with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) and Fibromyalgia (FM). (wellnessresources.com)

Conclusions Obesity is associated with higher symptomatology at 6 and 12 months and higher concentrations of blood inflammatory markers throughout recovery following mTBI. (bmj.com)

Anatomy12

Organisms5

Diseases84

Chemicals and Drugs39

Analytical, Diagnostic and Therapeutic Techniques and Equipment55

Psychiatry and Psychology12

Phenomena and Processes51

Anthropology, Education, Sociology and Social Phenomena4

Technology, Industry, Agriculture5

Information Science4

Named Groups7

Health Care40

Geographicals13

Diabetes37

Insulin15

Hypertension7

Prevalence13

Disorders4

Diseases13

Coronary artery1

Abdominal obesity4

Kidney6

Obese3

Overweight2

Incidence2

Comorbidities1

Multifactorial disease2

Cancer4

Myocardial infarction2

PREVENTING CHRONIC DISEASE1

Disease25

Atherosclerosis1

Inflammation9

Adults1

NAFLD2

Therapeutic2

Diagnosis4

20232

Causes of obesity3

Risk11

Prev Chronic Dis1

Anti-obesity6

Liver3

Visceral1

Immune3

Disorder1

Hepatic1

Microbiota3

Infection1

Systematic Review and Meta-Analysis1

Abnormalities1

Outcomes1

Severity1

Findings2

Induce1

Obstructive1

Prevention1

Severe1

Pediatric2

Abnormal2

Depression2

Triglycerides1

Fatigue Syndrome1

Inflammatory markers1