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  • Water
  • Parenterally administrable oil-in-water emulsions formed from nutritive oils, such as soybean and sunflower oils, are improved first by treating the nutritive oil with silicic acid to remove undesirable components such as peroxides, pigments, thermal and oxidative decomposition products, certain unsaponifiable. (google.ca)
  • contacting said nutritive oil with an adsorbant selected from the group consisting of silicic acid and silica gel, to substantially remove non-urea-adduct forming esters and unsaponifiable matter from said nutritive oil, recovering said oil from the adsorbant, and subsequently combining the recovered nutritive oil with sterile water and an emulsifier to produce an improved oil-in-water emulsion. (google.ca)
  • 2. A nutritive oil-in-water emulsion as described in claim 1, wherein said oil is mixed with a solvent at the time it is contacted with said adsorbant. (google.ca)
  • 3. A nutritive oil-in-water emulsion as described in claim 1, wherein said emulsion includes a tocopherol and a metal scavenger to inhibit the autoxidation of the emulsified oil. (google.ca)
  • 4. A nutritive oil-in-water emulsion as described in claim 3, wherein said oil recovered from said adsorbant is sunflower oil and contains no more than about 0.29% of non-urea-adduct-forming esters, and contains no more than about 0.34% unsaponifiable matter. (google.ca)
  • This invention relates to a nutritive oil in water emulsion for use in parenteral administration, wherein said nutritive oil is refined or purified soybean oil or sunflower oil. (google.ca)
  • The invention further relates to the purification of nutritive oils used in oil in water emulsions for parenteral feeding, such as soybean and sunflower oil, and in particular, the invention relates to the removal from such oils of undesirable components such as peroxides, pigments and thermal and oxidative decomposition products and polymers. (google.ca)