• Numerical simulation of cardiovascular dynamics with different types of VAD assistance, Shi Y, Korakianitis T, Bowles C, 2007. (cellml.org)
  • The simulation results show how similarly these two parameters modify gas mass flow rates, gas velocity fields, aspiration pressures in the melt delivery tube or the size of the recirculation zones below the melt nozzle. (unav.edu)
  • The stable download Windows для профессионалов (программирование в Win32 API position simulation electromagnetic was in its active modern set in 1998 maintained for choosing the possible and cardiovascular diesel of sonar multimedia from system trees, mock as after an metric in a new length page. (taido-hannover.de)
  • GREAT IDEA: Arnoldo Frigessi is the main person behind the new idea of making tens of thousands of virtual copies of the individual cancer patient and then testing all the treatments in a simulation model to find the most optimal treatment. (sciencenorway.no)
  • To study the physical and physiological determinants of transmitral and pulmonary venous flow, a lumped-parameter model of the cardiovascular system has been created, modeling the instantaneous pressure, volume, and influx/efflux of the pulmonary veins, left atrium and ventricle, systemic arteries and veins, right atrium and ventricle, and pulmonary arteries. (northwestern.edu)
  • This unified numericalexperimental programming environment should facilitate model refinement and physiological data exploration, in particular guiding more accurate interpretations of Doppler echocardiographic data. (northwestern.edu)
  • The cardiovascular system is one of the most fascinating and complex physiological systems. (edu.sa)
  • This expansion serves as the foundation for a component fault detection process to detect changes in the physiological parameters of the cardiovascular system which could be associated with cardiovascular anomalies such as atherosclerosis, aneurysm, high blood pressure, etc. (edu.sa)
  • Physiological modeling, tight glycemic control, and the ICU clinician: what are models and how can they affect practice? (springeropen.com)
  • Computational models of human physiology offer the potential, with clinical data, to create patient-specific models that capture a patient's physiological status. (springeropen.com)
  • Such models can provide new insights into patient condition by turning a series of sometimes confusing clinical data into a clear physiological picture. (springeropen.com)
  • This was accomplished using a simplified local model and a validated 3D finite element model. (techno-press.com)
  • Sensitivity analysis has been performed with a Jacobian matrix, representing the proportional change in a group of output indexes (y,-) in response to isolated changes in input parameters (x j ), [(oy i /y j -VCo-4/x i )], demonstrating the complementary nature of mitral and pulmonary venous A-wave velocity for predicting ventricular stiffness and atrial systolic function. (northwestern.edu)
  • Sensitivity analysis has been performed with a Jacobian matrix, representing the proportional change in a group of output indexes (y,-) in response to isolated changes in input parameters (xj), [(oyi/yj-VCo-4/xi)], demonstrating the complementary nature of mitral and pulmonary venous A-wave velocity for predicting ventricular stiffness and atrial systolic function. (northwestern.edu)
  • This model describes the human cardiovascular dynamics under a displacement pump type ventricular assist device (VAD) support using lumped-parameter modelling, based on the concept of hydraulic-electric analogue. (cellml.org)
  • Large animal models and computer simulations indicate that adding non-contractile material to the damaged left ventricular wall can potentially reduce myofiber stress. (ucsf.edu)
  • Department faculty members have teaching and research expertise in areas related to cardiovascular and fluid biomechanics, musculoskeletal biomechanics, biomaterials and tissue engineering, bioinstrumentation, biosystems, biomedical imaging, biological signal analysis, bioinformatics and computational biology, respiratory and pulmonary engineering, and other allied fields. (uiowa.edu)
  • The Biomechanics and Biomaterials Laboratory is equipped to perform experiments relating to the cardiovascular and human musculoskeletal systems as well as the various properties of biomaterials. (uiowa.edu)
  • The lab is used for the course BME:2500 Biomaterials and Biomechanics , elective courses in cardiovascular and musculoskeletal biomechanics, and senior design projects. (uiowa.edu)
  • Mascheroni, P., Penta, R., Merodio, J. (2023) The impact of vascular volume fraction and compressibility of the interstitial matrix on vascularised poroelastic tissues Biomechanics and Modeling in Mechanobiology, 22, pp. 1901-1917. (gla.ac.uk)
  • Miller, L., Penta, R. (2023) Investigating the effects of microstructural changes induced by myocardial infarction on the elastic parameters of the heart Biomechanics and Modeling in Mechanobiology, 22, pp. 1019-1033. (gla.ac.uk)
  • The splitting of the pulmonary and systemic circulation is not fixed, for example, if the interest of the study is in systemic capillaries, the compartment accounting for the systemic capillaries can be added to the lumped parameter model. (wikipedia.org)
  • A lumped parameter cardiovascular model is a zero-dimensional mathematical model used to describe the hemodynamics of the cardiovascular system. (wikipedia.org)
  • Extensive research based on experimental, analytical and numerical methods has sought to quantify the response of the human head to blunt impact in an attempt to explain the likely injury process. (techno-press.com)
  • Nonetheless, it will be shown that the hemodynamic equations developed by Euler about 275 years ago, still undergird the most advanced numerical methods in use today for blood flow analysis in arterial networks. (scirp.org)
  • A focus of this paper is that the model-based methods discussed here can provide patient-specific care that is robust to these intra- and inter-patient variabilities. (springeropen.com)
  • A concentrated parameter model for the human cardiovascular system including heart valve dynamics and atrioventricular interaction, Korakianitis T, Shi Y, 2006. (cellml.org)
  • In this review, we introduce the concept of computational fluid dynamics (CFD) modeling with a clinical perspective and we review the CFD models used to study RE from the fluid mechanics point of view. (unav.edu)
  • In this study, Computational Fluid Dynamics (CFD) techniques are used to model and simulate the gas flow in the melt nozzle area for a convergent-divergent, close-coupled gas atomiser in the absence of the melt stream. (unav.edu)
  • In this study, anatomically ac- curate computational fluid dynamics (CFD) models were used to and respiratory systems (ATSDR, 1999). (cdc.gov)
  • To test this hypothesis, computational fluid dynamics (CFD) models have been de- veloped to describe the uptake of inhaled H2S in rat nasal passages (Moulin et al. (cdc.gov)
  • Mathematical Biology is the application of mathematical modelling to solve problems in biology and physiology. (gla.ac.uk)
  • The lumped parameter model is used to study the hemodynamics of a three-dimensional space (the cardiovascular system) by means of a zero-dimensional space that exploits the analogy between pipes and electrical circuits. (wikipedia.org)
  • Given a set of parameters that have a physical meaning (e.g. resistances to blood flow), it allows to study the changes in blood pressures or flow rates throughout the cardiovascular system. (wikipedia.org)
  • The reduction from three to zero dimensions is performed by splitting the cardiovascular system into different compartments, each of them representing a specific component of the system, e.g. right atrium or systemic arteries. (wikipedia.org)
  • The lumped parameter model consists in a system of ordinary differential equations that describes the evolution in time of the volumes of the heart chambers, and the blood pressures and fluxes through the blood vessels. (wikipedia.org)
  • The lumped parameter model consists in a system of ordinary differential equations that adhere to the principles of conservation of mass and momentum. (wikipedia.org)
  • The system of ordinary differential equations is solved by means of a numerical method for temporal discretization, e.g., a Runge-Kutta method. (wikipedia.org)
  • In this thesis, a methodology for the detection of anomalies in the cardiovascular system is presented. (edu.sa)
  • Therefore, many studies have been devoted to modeling the cardiovascular system in order to better understand its behavior and find new reliable diagnosis techniques. (edu.sa)
  • The lumped parameter model of the cardiovascular system proposed in [1] is restructured using a hybrid systems approach in order to include a discrete input vector that represents the influence of the mitral and aortic valves in the different phases of the cardiac cycle. (edu.sa)
  • It is well known that the modern understanding of the cardiovascular system undoubtedly starts with the work of William Harvey (1578-1657) who published his discovery of the circulation of blood in 1628. (scirp.org)
  • The most important novelty of this study is related to experimental validation of the numerical results using the Particle Image Velocimetry (PIV) technique and through direct measurements of gas mass flow rates, with a clear correlation between simulated and measured data. (unav.edu)
  • Each heart chamber is modeled by means of the elastances that describe the contractility of the cardiac muscle and the unloaded volume, that is the blood volume contained in the chamber at zero-pressure. (wikipedia.org)
  • Wildhirt, S.M. (2015) A closed loop 0D-3D model of patient specific cardiac mechanics for cardiac assist device engineering , 4th Int. Conf. (tum.de)
  • In fact, although in the introduction to the problem (paragraphs 1-8), Euler focuses on the discussion on blood flow through arteries, to such a degree to even proposing adhoc models for the behavior of their elastic cross-sections, surprisingly, and also somehow disappointing, is that the main body of the manuscript (paragraphs 9-34) is devoted to the modeling of flows through rigid tubes, driven by a piston pump. (scirp.org)
  • The National Heart, Lung, and Blood Institute (NHLBI) under the Department of Health and Human Services is requesting that a Cardiovascular Disease Risk Factor Supplement be added to the September 1989 and 1990 Current Population Survey. (cdc.gov)
  • Human exposure to H2S results in dose-related human exposure to low levels of H2S is widespread due to its neurological, respiratory, and cardiovascular effects. (cdc.gov)
  • of rats to 80 ppm resulted in full thickness necrosis of the Scaled kinetic parameters were incorporated into a human CFD model to predict H olfactory mucosa on the dorsal meatus (Brenneman et al. (cdc.gov)
  • The model comprises three main parts: the heart, the systemic loop, and the displacement pump VAD, as illustrated in Fig. 1. (cellml.org)
  • The heart is modelled as a two-chambered pump with variable elastance and two heart valves to control the direction of blood flow. (cellml.org)
  • SPECIAL NOTE OMB Supporting Statement OMB SUPPORTING STATEMENT This statement is submitted by the National Heart, Lung, and Blood Institute (NHLBI), in support of a Cardiovascular Risk Factor Supplement to be added to the Current Population Survey (CPS). (cdc.gov)
  • The download Windows brings developed for a vast potassium, and the order is damped emitted out until method modeling 40000. (taido-hannover.de)
  • For instance, an estimate of 17.3 million people died in 2008 from cardiovascular diseases. (edu.sa)
  • This collection is authorized under 42 of the United States Code 285b-2 and 3, Sections 420 and 421 of the Public Health Service Act, as amended by the Health Research Extension Act (Attachment B). This requires the NHLBI to collect and disseminate information on the prevention and treatment of lung and cardiovascular disease to the public and various agencies, and other groups. (cdc.gov)
  • In the Fall 2019 Quarter, he taught a special study course (BioE 297: Physics-Based Modeling and In Silico Clinical Trials). (ucsf.edu)
  • This article presents the concept of model-based therapeutics, the use of computational models in clinical medicine and critical care in specific, as well as its potential clinical advantages, in a format designed for the clinical perspective. (springeropen.com)
  • The overall review clearly shows the concept and significant clinical potential of using computational models in critical care medicine. (springeropen.com)
  • Modifying the parameters, it is possible to study the effects of a specific disease. (wikipedia.org)
  • In what follows the focus will be on a specific lumped parameter model. (wikipedia.org)
  • These aspects directly address questions concerning what makes a model, how it is made patient-specific, what it can be used for, its limitations and, importantly, what constitutes sufficient validation. (springeropen.com)
  • The first numerical results obtained are presented. (edu.sa)
  • The proposed questions comprise the Cardiovascular Disease Risk Factor Supplement (Attachment A). This supplement will collect data on the prevalence of cigarette smoking and awareness and treatment of the two other major cardiovascular disease risk factors (high blood cholesterol and high blood pressure). (cdc.gov)
  • In each segment, individual components are modelled by representations of the local resistance to blood flow, vessel elasticity and the inertia of the blood. (cellml.org)
  • In this paper the properties and material modeling of the subarachnoid space (SAS) as it relates to Traumatic Brain Injuries (TBI) is investigated. (techno-press.com)
  • First the material modeling of the trabeculae in the Subarachnoid Space (SAS) was investigated and validated, then the validated material property was used in a 3D head model. (techno-press.com)
  • The current CellML model implementation runs in OpenCell. (cellml.org)