Nucleus of a somatic cell cell lines genetically clone cells. Medical search. Frequent questions

Some prohibit only cloning for reproductive purposes and allow the creation of cloned human embryos for research, whereas others prohibit the creation of cloned embryos for any purpose. (who.int)
In humans, a major roadblock in achieving successful SCNT leading to embryonic stem cells has been the fact that human SCNT embryos fail to progress beyond the eight-cell stage. (news-medical.net)
They derived several human embryonic stem cell lines from these cloned embryos whose DNA was an exact match to the adult cell that donated the DNA. (news-medical.net)
First, while stem-cell experimentation could involve the creation of embryos with the express purpose of destroying them, this is not the only means available for obtaining embryos. (jewishvaluesonline.org)
Thus, there is broad halakhic (Jewish legal) agreement that stem cell research is permitted on "excess" embryos. (jewishvaluesonline.org)
Most (but not all) authorities would forbid the creation of embryos with the express purpose of killing them in the pursuit of stem cell research. (jewishvaluesonline.org)
The controversy over stem cell research is focused specifically on the use of stem cells taken from embryos. (jewishvaluesonline.org)
These scientists destroyed the embryos and derived stem cell lines. (nationalrighttolifenews.org)
Most embryos…formed one or two pronuclei at the time of removal from TSA, whereas a slightly higher portion of embryos cleaved…suggesting that some SCNT embryos did not exhibit visible pronuclei at the time of examination… Most cleaved embryos developed to the eight-cell stage…but few progressed to compact morula…and blastocyst. (nationalrighttolifenews.org)
Activation of embryonic genes and transcription from the transplanted somatic cell nucleus are required for development of SCNT embryos beyond the eight-cell stage…Therefore, these results are consistent with the premise that our modified SCNT protocol supports reprogramming of human somatic cells to the embryonic state. (nationalrighttolifenews.org)
A story in News.Com.Au-which runs stories from several Australian newspapers celebrates the cloning breakthrough because it means no embryos are used in the process! (nationalrighttolifenews.org)
But it is an important step in research because it doesn't require the use of embryos in creating the type of stem cell capable of transforming into any other type of cell in the body. (nationalrighttolifenews.org)
The Los Angeles Times has waded in to the junk biology game, assuring us that no embryos are threatened in human cloning-WHEN THE WHOLE POINT OF HUMAN CLONING IS TO CREATE AN EMBRYO! (nationalrighttolifenews.org)
And now Washington joins the infamous list with Senate Bill 5594, a thoroughly disingenuous piece of legislation that purports to outlaw the cloning of human beings, but by manipulating language and redefining terms, actually permits human cloning and gestation of the resulting cloned embryos through the ninth month. (cbc-network.org)
Most human embryos reproduced by most human cloning techniques would actually be genetically unique -- i.e., having never existed before. (lifeissues.net)
Scientists have applied somatic cell nuclear transfer to clone human and mammalian embryos as a means to produce stem cells for laboratory and medical use. (asu.edu)
Stem cells may be derived from adult tissues but the most potent are extracted from developing human embryos. (edu.au)
Citizens disagree about whether we should destroy human embryos for their stem cells-and if so, which embryos, with whose money, under what regulatory guidelines. (eppc.org)
The holy grail of regenerative medicine-whatever one's ethical beliefs about destroying embryos-is to "reprogram" regular cells from one's own body so that individuals can be the source of their own rejection-proof therapies. (eppc.org)
That is to say, we risk turning developed cells into developing embryos, and thus risk engaging in the very activities of embryo destruction and human cloning that we seek to avoid. (eppc.org)
But we need to proceed carefully, recognizing that we are gaining new powers over human origins even when we do not use human embryos, and recognizing the danger of blurring the line between cellular parts and embryonic wholes. (eppc.org)
Far more controversial-and for good reason-are stem cells derived from destroyed human embryos. (eppc.org)
The somatic cell and the oocyte is then fused (f) and the embryos is allowed to develop to a blastocyst in vitro (g). (biomedcentral.com)
Currently, the efficiency for nuclear transfer is between 0-10%, i.e., 0-10 live births after transfer of 100 cloned embryos. (biomedcentral.com)
Stem cell technologies have been dogged by controversy because of objections over the morality of sacrificing human embryos to produce the first human embryonic stem cell lines. (schlich.co.uk)
There are three major ways to obtain stem cells with unlimited proliferation and differentiation capabilities, including 1) isolating embryonic stem cells (ESCs) from embryos, 2) isolating adult stem cells from adult tissues, and 3) in vitro reprogramming of differentiated somatic cells into induced pluripotent stem cells (iPSCs). (bvsalud.org)
Tetraploid embryos could be produced by electrofusion at the stage of two-cell embryos, which could develop to blastocysts followed by fusion of cytoplasm and nucleus and cleavage in vitro. (bvsalud.org)
Animals (or embryos) composed of cells of different genetic origin. (nationalacademies.org)
Cell lines derived from early embryos that have the potential to differentiate into all types of somatic cells as well as to form germ line cells, and hence whole animals, when injected into early embryos. (nationalacademies.org)
Patterns are ubiquitous in living systems and underlie the dynamic organization of cells, tissues, and embryos. (mpi-cbg.de)
Efficient generation of embryonic stem cells from single blastomeres of cryopreserved mouse embryos in the presence of signalling modulators. (axonmedchem.com)

The artificial cloning of organisms, sometimes known as reproductive cloning, is often accomplished via somatic-cell nuclear transfer (SCNT), a cloning method in which a viable embryo is created from a somatic cell and an egg cell. (wikipedia.org)
In the first 4 - 5 days after fertilization, the early-stage embryo (or blastocyst) is comprised of about 150 cells, within which there is a region called the Inner Cell Mass containing the stem cells. (jewishvaluesonline.org)
The controversy arises for some people because, in the course of harvesting these cells, the embryo is destroyed. (jewishvaluesonline.org)
In this process, all the DNA in a fertilized egg is taken out and the DNA from an edited cell line is transferred in to make an gene-edited embryo. (innovativegenomics.org)
After many divisions in culture, this single cell forms a blastocyst (an early stage embryo with about 100 cells) with almost identical DNA to the original donor who provided the adult cell - a genetic clone. (eurostemcell.org)
The early mammalian embryo consists of the extra-embryonic cell layers-the trophoblast and a body of cells called the inner cell mass (ICM), which eventually become the embryo proper. (thefutureofthings.com)
Park Se-pill, head of Seoul-based fertility clinic Maria Biotech, said the tests can silence Hwang's critics who have suggested the dog might be a twin created from a split embryo rather than a clone. (blogspot.com)
creates a cloned embryo. (nationalrighttolifenews.org)
A cloned embryo-like a natural embryo-is an individual organism, a member of its (in this case, human) species. (nationalrighttolifenews.org)
After that, the question becomes not whether to clone, but what to do with the embryo that was created through the cloning process. (nationalrighttolifenews.org)
A little shot of electricity comes next, and if all goes well, a new human cloned embryo comes into being and begins to develop in the same way as a sexually created embryo. (cbc-network.org)
Cloning of a human being" means asexual reproduction by implanting or attempting to implant the product of nuclear transplantation [e.g., an embryo] into a uterus or substitute for a uterus with the purpose of producing a human being. (cbc-network.org)
Embryonic stem (ES) cells are derived from the embryo and are pluripotent, thus possessing the capability of developing into any organ, cell type or tissue type. (justia.com)
Thus to use the phrase "of an existing or previously existing human being" to refer to the product of human cloning would not be a scientifically accurate description of the cloned or genetically engineered human embryo -- thus creating yet another loophole in the bill or treaty. (lifeissues.net)
Research advocates attack President Bush for "banning stem cell research," while pro-life advocates lament a Republican administration and Congress that have banned nothing-not embryo destruction, not human cloning, not fetal farming, not genetic engineering. (eppc.org)
Before leaving office, President Clinton sought to get around the existing law without actually changing it, by funding research on embryonic stem cells so long as the actual embryo destruction was paid for with private dollars. (eppc.org)
… "embryo" means a human organism during the first 56 days of its development following fertilization or creation, excluding any time during which its development has been suspended, and includes any cell derived from such an organism that is used for the purpose of creating a human being. (hinxtongroup.org)
… "human clone" means an embryo that, as a result of the manipulation of human reproductive material or an in vitro embryo, contains a diploid set of chromosomes obtained from a single - living or deceased - human being, fetus, or embryo. (hinxtongroup.org)
It is also our view that there are no sound reasons for treating the early-stage human embryo or cloned human embryo as anything special, or as having moral status greater than human somatic cells in tissue culture. (wikiquote.org)
Blastocyst -A preimplantation embryo of about 150 cells. (cellmedicine.com)
Embryonic germ cells -Cells found in a specific part of the embryo/fetus called the gonadal ridge that normally develop into mature gametes. (cellmedicine.com)
Embryonic stem cells -Primitive (undifferentiated) cells from the embryo that have the potential to become a wide variety of specialized cell types. (cellmedicine.com)
These cells give rise to the embryonic disk of the later embryo and, ultimately, the fetus. (cellmedicine.com)
Although the efficiency of nuclear transfer has been dramatically improved from the initial success rate of one live clone born from 277 embryo transfers [ 1 ], none of the aforementioned efforts abolished the common problems associated with nuclear transfer. (biomedcentral.com)
Mouse naive embryonic stem cells have recently been shown to give rise to embryonic and extra-embryonic stem cells capable of self-assembling into post-gastrulation structured stem-cell-based embryo models with spatially organized morphogenesis (called SEMs) 3 . (nature.com)
This question had been asked by embryologists since 1886 ( Rauber, 1886 ), and Spemann ( Spemann, 1938 ) had demonstrated by an egg ligation experiment that the nuclei of an eight-cell frog embryo are developmentally totipotent. (biologists.com)
However, Briggs and King ( Briggs and King, 1957 ) had also found that the nucleus of an endoderm cell from a neurula embryo could no longer support normal development ( Fig. 2 ). (biologists.com)
But it is perhaps not auspicious to quote him for purposes of the scientific debates on human cloning, because Ramsey agreed with and supported the scientific myth of the "pre-embryo" 47 made famous by Jesuit Richard McCormick and frog embryologist Clifford Grobstein. (lifeissues.net)
Perhaps Ramsey would give other extraordinarily powerful arguments as to why human cloning is unethical, but he obviously would not be able to base it on his unscientific "pre-embryo" position. (lifeissues.net)
Otherwise, such a treaty would not recognize the inherent human nature of the early human embryo or fetus until after birth , and thus cloning them and using them for research - both "therapeutic" and "reproductive" -- would not be banned, and women undergoing "infertility treatments" could surely be put in danger. (lifeissues.net)
Again, Saunders is referring to SCNT as "THE" cloning procedure, when there are many other ways to clone a human being as well, and he is scientifically mis-defining the product of SCNT (i.e., the cloned human embryo). (lifeissues.net)
Revealing cell populations catching the early stages of the human embryo development in naïve pluripotent stem cells. (axonmedchem.com)

The use of embryonic stem cells, which can be produced through SCNT, in some stem cell research has attracted controversy. (wikipedia.org)
Indeed, if passed, Hatch/Feinstein/Kerry would explicitly legalize doing in humans the very cloning procedure -- somatic cell nuclear transfer (SCNT) -- that was used to make Dolly the sheep . (lifeissues.net)
Comment: Indeed, if passed, "total cloning bans" H.R. 534, H.R. 234, H.R. 916, and S. 245 would not ban anything either - not even the SCNT cloning technique that was used to make Dolly the sheep. (lifeissues.net)
One cloning technology that has been developed for mammalian and human cells is somatic cell nuclear transfer (SCNT). (news-medical.net)
SCNT is a method of cloning mammalian cells that can be used to create personalized embryonic stem cells from an adult animal or human. (news-medical.net)
This has led to a lot of interest in SCNT, which is best known as the method used to pioneer whole animal cloning technology, such as Dolly the sheep. (news-medical.net)
But SCNT can also be used to clone human cells for transplant or other therapies. (news-medical.net)
This was the first successful reprogramming of human somatic cells into embryonic stem cells using a cloning technique, SCNT. (news-medical.net)
Another successful attempt at human SCNT was made using cells from two adult males. (news-medical.net)
Cloning, or somatic cell nuclear transfer (SCNT), is the technique used to produce Dolly the sheep, the first animal to be produced as a genetic copy of another adult. (eurostemcell.org)
Once the SCNT is done, the cloning is over. (nationalrighttolifenews.org)
The cloning is completed when the SCNT is accomplished. (nationalrighttolifenews.org)
The primary cloning technique is called "somatic cell nuclear transfer" (SCNT). (cbc-network.org)
If the authors of this bill really meant what they appear to have written, their legislation would ban all human cloning, since as we have seen, biologically, a new human organism, that is, a new human being, comes into existence with the completion of SCNT. (cbc-network.org)
This is junk biology since implanting isn't the act of asexual reproduction: SCNT cloning is. (cbc-network.org)
Somatic cell nuclear transfer (SCNT) is a technology applied in cloning, stem cell research and regenerative medicine. (asu.edu)

Elaboration of an international convention against reproductive cloning of human beings has been under consideration in the United Nations since December 2001 when the subject was included in the agenda of the fifty- sixth session as a supplementary agenda item at the request of France and Germany. (who.int)
When the cloning process is used in this way, to produce a living duplicate of an existing animal, it is commonly called reproductive cloning. (eurostemcell.org)
In most countries, it is illegal to attempt reproductive cloning in humans. (eurostemcell.org)
If it is to be brought to birth, the process is usually called "reproductive cloning. (cbc-network.org)
Many of these accurate definitions can also be used in bills and treaties concerning related issues, e.g., human embryonic stem cell research, human genetic engineering, abortion, the use of abortifacients, conscience clauses, IVF and other artificial reproductive technology research and regulation, etc. (lifeissues.net)
Note that each and every individual "loophole" discussed below that permits human cloning by default (and most bills have literally dozens of such loopholes) thus permits it for both "therapeutic" and for "reproductive" human cloning. (lifeissues.net)
and the general public debate about reproductive cloning. (edu.au)
Reproductive cloning is expensive and highly inefficient. (wikiquote.org)
Reproductive Cloning - Use of a donor cell to create a new human genetically identical to the donor. (schlich.co.uk)
Since the term "born" has been used as an essential part of the definition of " reproductive cloning " used by Weissman, the National Academy of Sciences, etc., then it is critical to use the accurate term with the proper meaning. (lifeissues.net)

The therapeutic potential of cloned human cells has been demonstrated by another study using human oocytes to reprogram adult cells of a type 1 diabetic. (news-medical.net)
Although attempts have not yet been made to create a therapeutic transplant from embryonic stem cells, the methods have been developed to allow the creation of functional, mature cells using human cell cloning technology. (news-medical.net)
In therapeutic cloning, the blastocyst is not transferred to a womb. (eurostemcell.org)
Another long-term hope for therapeutic cloning is that it could be used to generate cells that are genetically identical to a patient. (eurostemcell.org)
To date, no human embryonic stem cell lines have been derived using therapeutic cloning, so both these possibilities remain very much in the future. (eurostemcell.org)
A number of large biotech companies and scientists are looking toward stem cells as the basis for a therapeutic solution to cure such illnesses as blindness, diabetes and spinal cord injuries. (thefutureofthings.com)
If the cloned human organism is to be experimented upon and destroyed, the process is often called "therapeutic cloning. (cbc-network.org)
The present invention also provides methods of using the differentiated cells of the present invention for therapeutic purposes. (justia.com)
In particular, the induction of stem cells to differentiate into muscle cells (myocytes) is useful for muscle transplantation and therapeutic purposes, as well as providing potential human disease models in culture (e.g. for testing pharmaceuticals). (justia.com)
The induction of cardiomyocyte differentiation in stem cells is especially useful in developing therapeutic methods and products for heart disease and abnormal heart conditions. (justia.com)
But adult stem cells also raise some interesting ethical dilemmas alongside their great therapeutic promise. (eppc.org)
Therapeutic Cloning - Use of a donor cell to create pluripotent stem cells suitable for growing tissues for implantation into the donor or other patient. (schlich.co.uk)
Studies have increasingly focused on the potential therapeutic effects of stem cell transplantation for neurological diseases [ 10 ]. (hindawi.com)
Conventional therapeutic approaches for tumor angiogenesis, which are primarily focused on the inhibition of active angiogenesis to starve cancerous cells, target the vascular endothelial growth factor signaling pathway. (biomedcentral.com)
Direct neuronal reprogramming of a somatic cell into therapeutic neurons, without a transient pluripotent state, provides new promise for the large number of individuals afflicted by neurodegenerative diseases or brain injury. (lu.se)

Scientists were initially interested in somatic-cell nuclear transfer as a means of determining whether genes remain functional even after most of them have been switched off as the cells in a developing organism assume their specialized functions as blood cells, muscle cells, and so forth. (who.int)
It may also be part of asexual reproduction, which is a process where a single parent organism produces genetically identical offspring by itself. (wikipedia.org)
If artificial cloning and natural cloning both lead to the same result, which is the formation of a clone, that is, an organism with identical or nearly identical genes to another organism, then the plight of This creation is very different between the two creatures. (wikipedia.org)
These stem cells are genetically matched to the donor organism, holding promise for studying genetic disease. (eurostemcell.org)
At the top of the list comes the zygote-a fertilized egg, which of course has the ability to divide and differentiate into all cell types in the body and create a new organism. (thefutureofthings.com)
The first three divisions of the zygote give birth to eight totipotent cells, each of which also has the ability to become an entire organism. (thefutureofthings.com)
At that point - and this is important to understand - there is no more cloning to be done since a new human organism now exists. (cbc-network.org)
Or to put it the other way around, cloning, not implantation, is what produces a new and distinct human organism. (cbc-network.org)
What surprises many people is that every body cell of an animal - indeed, of any multicellular organism - carries its entire genome. (learner.org)
If it doesn't, daughter cells won't form properly (or at all) and this may have a negative impact on the entire organism. (learner.org)
This is important because male and female sex cells ultimately join to become a fertilized egg, which gives rise to a new organism, or offspring. (learner.org)
XI - embryonic stem cells: embryonic cells that are capable of modifying the cells of any organism tissue. (hinxtongroup.org)
Microenvironment -The molecules and compounds such as nutrients and growth factors in the fluid surrounding a cell in an organism or in the laboratory, which are important in determining the characteristicsof the cell. (cellmedicine.com)
On the other hand, a chimera is defined as an organism in which cells from two or more different organisms have contributed. (frontiersin.org)

That is what New Jersey legislators did when they passed and then Governor James McGreevey signed S-1909 last year, a law that was sold to the public as outlawing human cloning but which actually permits the creation of cloned human life, and its implantation and gestation up to and including the very moment prior to the emergence of the cloned baby from the birth canal. (cbc-network.org)

Most natural cloning occurs in those species that produce their descendants asexually, that is, without combining the male and female genetic material. (who.int)
if it implants and the pregnancy goes to term, the resulting individual will carry the same nuclear genetic material as the donor of the adult somatic cell. (who.int)
However, an animal created through this technique would not be a precise genetic copy of the source of its nuclear DNA because each clone derives a small amount of its DNA from the mitochondria of the egg (which lie outside the nucleus) rather than from the donor of cell nucleus. (who.int)
Natural cloning is the production of clones without the involvement of genetic engineering techniques. (wikipedia.org)
The main difference between the two is that natural cloning does not involve any human intervention, whereas artificial cloning is a genetic engineering technique. (wikipedia.org)
The university has been conducting a probe on Hwang and his research since Dec. 16, including genetic tests on stem cells being stored at the laboratories. (blogspot.com)
Lytic cycle - the replication process in viruses in which the virus's genetic material uses the copying machinery of the host cell to make new viruses. (edrawmind.com)
Replication - the fundamental process of all cells, in which the genetic material is copied before the cell reproduces. (edrawmind.com)
Succesful cloning from a cancer cell, succesful cloning from old adult organisms, repeated cloning of old adult organisms without compromising health(that is clones from clones from clones, second and third generation clones), and the like have shown, unless I missed some news, that IMHO it seems no permanent or at least significantly impairing damage at a genetic level seems to be occuring with aging. (fightaging.org)
Even some cancers seem to be unable to significantly do damage that permanently impairs genetic function given the healthy clone obtained out of a cancer cell. (fightaging.org)
The laboratory technique of maintaining live cell lines (a population of cells descended from a single cell and containing the same genetic makeup) separated from their original tissue source became more robust in the middle 20th century. (wikipedia.org)
In the field of agriculture, the efficient purification, culture and establishment of livestock and poultry stem cell lines are expected to significantly improve the efficiency of somatic cell cloning and genetic modification of cells. (bvsalud.org)

The term applies not only to entire organisms but also to copies of molecules (such as DNA) and cells. (who.int)
Cloning is the process of producing individual organisms with identical genomes, either by natural or artificial means. (wikipedia.org)
In the field of biotechnology, cloning is the process of creating cloned organisms of cells and of DNA fragments. (wikipedia.org)
Natural cloning occurs through a variety of natural mechanisms, from single-celled organisms to complex multicellular organisms. (wikipedia.org)
Sex cells, or gametes, are unique to organisms that reproduce sexually. (learner.org)
In the second half of the twentieth century, scientists learned how to clone organisms in some species of mammals. (asu.edu)
In biology , cloning is the process of producing similar populations of genetically identical individuals that occurs in nature when organisms such as bacteria , insects or plants reproduce asexually . (wikiquote.org)
Cloning in biotechnology refers to processes used to create copies of DNA fragments ( molecular cloning ), cells (cell cloning), or organisms . (wikiquote.org)
I think, we've seen several hints that the cellular machinery of life is far more powerful and versatile than most believed, it certainly doesn't seem like something that would just decay, Multi-celled organisms seem quite capable of faithfully preserving their genes(even after going through aging several times, third gen clones) and seems to have vast innate regeneration potential. (fightaging.org)

Cloning of human cells is a technology that holds the potential to cure many diseases and provide a source of exactly matched transplant tissues and organs. (news-medical.net)
In the normal course of gestation, these cells will divide and split off from one another to become every cell in the human body, forming the various organs and tissues. (jewishvaluesonline.org)
In the other, gold-plated DNA is projected at plant tissues at high speeds and pressures to penetrate into the plant cell. (innovativegenomics.org)
They are found mainly in renewing tissues, such as the skin, the inner lining of the gastrointestinal tract and blood tissues. (thefutureofthings.com)
In addition to their ability to supply cells at the turnover rate of their respective tissues, they can be stimulated to repair injured tissue caused by liver damage, skin abrasions and blood loss. (thefutureofthings.com)
The ability of our body to regenerate some of its tissues is largely owed to the reserves of adult stem cells. (thefutureofthings.com)
Dec. 29, 2005 -- South Korean laboratories used by scientist Hwang Woo Suk no longer have any stem cells created from patients' tissues, the result of the researcher's landmark May 2005 paper, the Seoul National University said. (blogspot.com)
This long-sought technique may eventually let doctors create replacement cells for a wide variety of tissues from bits of a patient's own skin. (nationalrighttolifenews.org)
Today, we can derive stem cells from a range of adult and newborn tissues: liver cells, kidney cells, brain cells, fat cells, and umbilical cord blood. (eppc.org)
Astrocyte -One of the large neuroglia cells of neural tissues. (cellmedicine.com)
Cell-based therapies -treatment in which stem cells are induced to differentiate into the specific cell type required to repair damaged or depleted adult cell populations or tissues. (cellmedicine.com)
Stem cell technologies promise to be the next transformative medical technology offering therapies for conditions and diseases that are currently beyond medical science by creating replacement or supplementary tissues for a patient. (schlich.co.uk)
reagents made using a patient's own cells used to regenerate disease or damaged tissues 14,15 , once the stuff of science fiction, may become science fact. (schlich.co.uk)
Much of this process relies on the morphogenesis of the extra-embryonic tissues and the effect this has on the organization of embryonic cells. (nature.com)
Tissue culture commonly refers to the culture of animal cells and tissues, with the more specific term plant tissue culture being used for plants. (wikipedia.org)
[12] He suggested that the potentialities of individual cells via tissue culture as well as that the reciprocal influences of tissues on one another could be determined by this method. (wikipedia.org)
Transplantation of cells, tissues, or organs from another member of the same species. (nationalacademies.org)
Mechanochemical Principles of Spatial and Temporal Patterns in Cells and Tissues. (mpi-cbg.de)
The wide range of manifestations observed in patients with mitochondrial disease results from varying fractions of abnormal mtDNA molecules in different cells and tissues, a phenomenon termed heteroplasmy. (jci.org)
However, the landscape of heteroplasmy across cell types within tissues and its influence on phenotype expression in affected patients remains largely unexplored. (jci.org)

For instance, it may be possible one day to produce cardiac tissue to repair a heart damaged in a heart attack, nerve tissue to repair spinal cord injuries and cell therapies to treat people suffering from Alzheimer's or ALS. (jewishvaluesonline.org)
Methods of inducing differentiation in stem cells and muscle cells produced therefrom may be used for the study of cellular and molecular biology of tissue development, for the discovery of genes and proteins such as differentiation factors that play a role in tissue development and regeneration. (justia.com)
The uniqueness of tissue engineering is that it can restore normal structure in addition to repairing tissue function, and is often accomplished using stem cells. (asu.edu)
The first type of tissue engineering using stem cells was hematopoietic stem cell transplantation (HSCT), a surgical procedure in which hematopoietic stem cells (HSCs) are infused into a host to treat a variety of blood diseases, cancers, and immunodeficiencies. (asu.edu)
If there are intact cells in this tissue they have been 'stored' frozen. (wikiquote.org)
A blastocyst (cloned or not), because it lacks any trace of a nervous system, has no capacity for suffering or conscious experience in any form - the special properties that, in our view, spell the difference between biological tissue and a human life worthy of respect and rights. (wikiquote.org)
Adult stem cell -An undifferentiated cell found in a differentiated tissue that can renew itself and (with certain limitations) differentiate to yield all the specialized cell types of the tissue from which it originated. (cellmedicine.com)
Bone marrow stromal cells -A stem cell found in bone marrow that generates bone, cartilage, fat, and fibrous connective tissue. (cellmedicine.com)
Mesenchymal stem cells -Cells from the immature embryonic connective tissue. (cellmedicine.com)
It demonstrated that genes inactivated during tissue differentiation can be completely re-activated by a process called nuclear reprogramming: the reversion of a differentiated nucleus back to a totipotent status. (biomedcentral.com)
Cell culture or tissue culture is the process by which cells are grown under controlled conditions, generally outside of their natural environment. (wikipedia.org)
After the cells of interest have been isolated from living tissue , they can subsequently be maintained under carefully controlled conditions. (wikipedia.org)
In practice, the term "cell culture" now refers to the culturing of cells derived from multicellular eukaryotes , especially animal cells, in contrast with other types of culture that also grow cells, such as plant tissue culture , fungal culture, and microbiological culture (of microbes ). (wikipedia.org)
The historical development and methods of cell culture are closely interrelated to those of tissue culture and organ culture . (wikipedia.org)
Since Haberlandt's original assertions, methods for tissue and cell culture have been realized, leading to significant discoveries in biology and medicine. (wikipedia.org)
Optical techniques for actuation and sensing provide instant parallelism, enabling contactless dynamic HT testing of cells and small-tissue constructs, not affordable by other means. (nature.com)
However, obtaining primary neuronal cells from adult tissue is difficult and faces major ethical issues in clinical practice. (hindawi.com)
Here, we identify nonrandom distribution of a pathogenic mtDNA variant across a complex tissue using single-cell RNA-Seq, mitochondrial single-cell ATAC sequencing, and multimodal single-cell sequencing. (jci.org)
Transplantations of fetal tissue in the 1980s and 1990s provided proof-of-concept for the potential of cell replacement therapy for PD and some patients benefitted greatly from their transplants. (lu.se)
However, post-mortem analysis of transplanted tissue revealed accumulation of pathological Lewy bodies in a small subset of transplanted cells over time, revealing a host-to-graft disease propagation. (lu.se)

In the case of asexually creating a human, the biotechnologist removes the nucleus from a mature human egg (an oocyte). (cbc-network.org)
Somatic cell cloning (cloning or nuclear transfer) is a technique in which the nucleus (DNA) of a somatic cell is transferred into an enucleated metaphase-II oocyte for the generation of a new individual, genetically identical to the somatic cell donor (Figure 1 ). (biomedcentral.com)
A matured oocyte (c) is then enucleated (d) and a donor cell is transferred into the enucleated oocyte (e). (biomedcentral.com)
7. "[footnote 16]: The cloning procedure supplies the oocyte with a complete set of chromosomes, all of which are contained in the nucleus which is transferred into the denucleated oocyte. (lifeissues.net)

In rodents, and even in some preliminary trials in humans, human embryonic stem cells have been shown to bridge gaps in spinal cord injuries , allowing restoration of motor functions. (thefutureofthings.com)
For humans, we know there are 46 chromosomes in body cells existing as 23 pairs. (learner.org)
Scientists use immortal human cell lines in their research to investigate how cells function in humans. (asu.edu)
Stem cell technology in humans derives from earlier and complementary work in animal studies. (edu.au)
Here we extend those findings to humans using only genetically unmodified human naive embryonic stem cells (cultured in human enhanced naive stem cell medium conditions) 4 . (nature.com)

Although many species produce clonal offspring in this fashion, Dolly, the lamb born in 1996 at a research institute in Scotland, was the first asexually produced mammalian clone. (who.int)
Somatic-cell nuclear transfer, the technique by which Dolly was created, was first used 40 years ago in research with tadpoles and frogs. (who.int)
In 1996, Dolly the sheep achieved notoriety for being the first mammal cloned from a somatic cell. (wikipedia.org)
To produce Dolly, the cloned blastocyst was transferred into the womb of a recipient ewe, where it developed and when born quickly became the world's most famous lamb. (eurostemcell.org)

It is the policy of Washington state that research involving the derivation and use of human embryonic stem cells, human embryonic germ cells, and human adult stem cells from any source, including somatic cell nuclear transplantation , is permitted upon full consideration of the ethical and medical implications of this research. (cbc-network.org)
The induction of a specific differentiated cell type can be useful for transplantation or drug screening and drug discovery in vitro. (justia.com)
To take human organ generation via BC and transplantation to the next step, we reviewed current emerging organ generation technologies and the associated efficiency of chimera formation in human cells from the standpoint of developmental biology. (frontiersin.org)
As a brand new graduate student starting in October 1956, my supervisor Michail Fischberg, a lecturer in the department of Zoology at Oxford, suggested that I should try to make somatic cell nuclear transplantation work in the South African frog Xenopus laevis . (biologists.com)
this limitation has been overcome via ectopic expression of human telomerase reverse transcriptase (hTERT), the catalytic component of telomerase, to produce large quantities of these cells as an attractive source for cellular transplantation [ 16 - 18 ]. (hindawi.com)

By transferring adult cell DNA into an embryonic stem cell, it is possible to create a line of immortal embryonic cells that are able to develop into any type of adult cell, genetically identical to the donor. (news-medical.net)

The second way to reproduce is a strictly human invention - known as "asexual" reproduction - or more commonly, cloning. (cbc-network.org)

Occasionally, the term cloning is misleadingly used to refer to the identification of the chromosomal location of a gene associated with a particular phenotype of interest, such as in positional cloning. (wikipedia.org)
The big difference between animals and plants is how the gene-editing machinery is delivered into cells. (innovativegenomics.org)
During differentiation the expression of stem cell specific genes and markers are often lost and cells acquire gene expression profiles of somatic cells or their precursors. (justia.com)
It notes the link between gene expression and cell differentiation by addressing how referencing extracellular signals having have a key role in differentiation, as they by triggering intracellular signalling pathways that impact gene expression. (oxfordsciencetrove.com)
Bone marrow stem cells, including the pluripotent hematopoietic stem cells (HSCs) and bone mesenchymal stem cells (BMSCs), are being considered as potential targets for cell and gene therapy-based approaches against a variety of different diseases. (hindawi.com)
We found that Dusp4 loss alone is insufficient in mediating tumorigenesis, but alternatively converges with loss in Trp53 and MYC amplification to induce tumorigenesis primarily through chromosome 5 amplification, which specifically upregulates Dbf4 , a cell cycle gene that promotes cellular replication by mediating cell cycle checkpoint escape. (biomedcentral.com)
Positional cloning efforts revealed that this locus contains the SWI/SNF related, matrix-associated, actin-dependent regulator of chromatin, subfamily B, member 1 ( SMARCB1 ) gene, also known as human sucrose non-fermenting gene number 5 ( hSNF5 ), integrase interactor 1 ( INI1 ) , or 47-Kd Brg1/Bam -associated factor ( BAF47 ). (medscape.com)

Another example of artificial cloning is molecular cloning, a technique in molecular biology in which a single living cell is used to clone a large population of cells that contain identical DNA molecules. (wikipedia.org)
Molecular cloning refers to the process of making multiple molecules. (wikipedia.org)
However, a number of other features are needed, and a variety of specialised cloning vectors (small piece of DNA into which a foreign DNA fragment can be inserted) exist that allow protein production, affinity tagging, single-stranded RNA or DNA production and a host of other molecular biology tools. (wikipedia.org)
However, the molecular pathways that lead to specification and terminal differentiation of specific cell types, such as myocytes, from embryonic stem cells during development are not entirely clear. (justia.com)
Defines both molecular clones and whole-animal clones. (nationalacademies.org)
Furthermore, the Spätzle (Spz) family ligands for the Toll receptor are transcriptionally upregulated by activated JNK signalling in a non-cell-autonomous manner, providing a molecular mechanism for JNK-induced Toll pathway activation. (sdbonline.org)
Molecular Cell , 82 (1), 190-208. (axonmedchem.com)
Molecular cell, 82(1), 106-122. (axonmedchem.com)

If embryonic stem-cell research offers real possibilities for future cures then, from a Jewish point of view, it may be pursued with caution, humility, and strict supervision. (jewishvaluesonline.org)
While regarded by many top scientists as the Holy Grail of medicine, others consider embryonic stem-cell research sacrilegious. (thefutureofthings.com)
Experts from around the world are assessing the difficult issue of the extent to which embryonic stem cell research should be allowed to proceed, and to date there is little international consensus on this matter. (edu.au)
How, then, should embryonic stem cell research be regulated in Australia? (edu.au)
In this article we examine embryonic stem cell research and explore the current regulatory framework associated with this research in Australia, with particular reference to the Andrews Report . (edu.au)

As the embryonic cells divide and the daughter cells differentiate, they become increasingly specific. (thefutureofthings.com)
The ICM continues to differentiate into three germ layers-ectoderm, mesoderm and endoderm, each of which follows a specific developmental destiny that takes them along an ever-specifying path at which end the daughter cells will make up the different organs of the human body. (thefutureofthings.com)
These adult stem cells are considered multipotent, having the ability to differentiate into different cell types, albeit with a more limited repertoire than embryonic stem cells. (thefutureofthings.com)
A particular field encouraged by the foundation is stem-cell research, with the great hope that it will result in the ability to get cells to differentiate into neurons and support cells to bridge the gap of a spinal cord injury. (thefutureofthings.com)
Generally, when a stem cell culture is induced to differentiate, the differentiated population is analysed for particular cell types by expression of genes, markers or phenotypic analysis. (justia.com)
Stem cells are undifferentiated cells that can shift, or differentiate, into specialized types of cells and serve as a repair system in the body by dividing indefinitely to replenish other cells. (asu.edu)

In this procedure, the nucleus of an egg cell is removed and replaced by the nucleus of a cell from another adult. (eurostemcell.org)
Various strategies have been employed to modify donor cells and the nuclear transfer procedure in attempts to improve the efficiency of nuclear transfer. (biomedcentral.com)

This chapter discusses the radial glial cells that serve as the neural stem cells in the embryonic and fetal brain. (oxfordsciencetrove.com)

The present report gives an overview of the terms and methods used in cloning and summarizes the debates in the General Assembly. (who.int)
The present invention relates to methods of inducing differentiation of stem cells. (justia.com)
In particular, the invention relates to methods of inducing differentiation of embryonic stem cells into muscle cells or vascular endothelial cells. (justia.com)
The invention also includes cells, cell lines, testing models and culture systems used in the methods of the present invention and differentiated cells produced therefrom. (justia.com)
Therefore there remains a need for providing effective methods of inducing differentiation of stem cells into specific cell types, such as myocytes or endothelial cells. (justia.com)
Cell Reports Methods. (reprocell.com)

These developmental defects have been attributed to incomplete reprogramming of the somatic nuclei by the cloning process. (biomedcentral.com)
Developmental defects, including abnormalities in cloned fetuses and placentas, in addition to high rates of pregnancy loss and neonatal death have been encountered by every research team studying somatic cloning. (biomedcentral.com)

Cloning has been proposed as a means of reviving extinct species. (wikipedia.org)
depictions commonly involve themes related to identity, the recreation of historical figures or extinct species, or cloning for exploitation (i.e. cloning soldiers for warfare). (wikipedia.org)
Bacterium (plural bacteria) - an individual prokaryotic cell or a single species that is in the domain. (edrawmind.com)
Given that we have an efficiency of 1% cloning for livestock species and if only one in a thousand cells are viable then around 100,000 cells would need to be transferred. (wikiquote.org)
However, somatic cloning has been inefficient in all species in which live clones have been produced. (biomedcentral.com)
Because cattle are a species widely used for nuclear transfer studies, and more laboratories have succeeded in cloning cattle than any other specie, this review will be focused on somatic cell cloning of cattle. (biomedcentral.com)

Briggs and King ( Briggs and King, 1952 ) had already succeeded in transplanting a blastula cell nucleus into an enucleated egg and obtaining normal tadpoles in the frog Rana pipiens . (biologists.com)
Even advanced donor cells from the endoderm of Xenopus tadpoles have nuclei that can sometimes yield normal individuals after nuclear transfer [data taken from Briggs and King ( Briggs and King, 1957 ) for Rana and from Gurdon ( Gurdon, 1962 ) for Xenopus ]. (biologists.com)

It was believed that the epigenetic signature and age-related changes such as shortened telomeres and oxidative DNA damage might hinder reprogramming of mature adult nuclei. (news-medical.net)

The mitochondrial DNA of the stem cells, however, matched the donor egg's mitochondrial DNA. (news-medical.net)
The nucleus of a body cell from the DNA donor is removed, and put into the place formerly occupied by the egg's nucleus. (cbc-network.org)

In sexual reproduction, clones are created when a fertilized egg splits to produce identical (monozygous) twins with identical genomes. (who.int)
Developments in biotechnology have raised new concerns about animal welfare, as farm animals now have their genomes modified (genetically engineered) or copied (cloned) to propagate certain traits useful to agribusiness, such as meat yield or feed conversion. (wikiquote.org)

your supposed cloning ban actually authorizes human cloning, implantation, and gestation through the ninth month. (cbc-network.org)
The blastocyst can then be transferred to a recipient (h) and cloned animals are born after completion of gestation (i). (biomedcentral.com)

The fact that the DNA of a fully differentiated (adult) cell could be stimulated to revert to a condition comparable to that of a newly fertilized egg and to repeat the process of embryonic development demonstrates that all the genes in differentiated cells retain their functional capacity, although only a few are active. (who.int)
Embryonic stem cells are immortal, and have the potential to develop into any type of adult cell, even after months growing in culture dishes. (news-medical.net)
The cloning method is based on the fact that cytoplasmic factors in mature, metaphase II oocytes are able to reset the identity of a transplanted adult cell nucleus to an embryonic state. (news-medical.net)
The adult cell nuclei were transferred into metaphase-II stage human oocytes, producing a karyotypically normal diploid embryonic stem cell line from each of the adult male donor cells. (news-medical.net)
After being inserted into the egg, the adult cell nucleus is reprogrammed by the host cell. (eurostemcell.org)
For example, stem cells could be generated using the nuclear transfer process described above, with the donor adult cell coming from a patient with diabetes or Alzheimer's. (eurostemcell.org)

article: Now, he's done it again by signing up as a co-sponsor (along with Senators Orin Hatch and Dianne Feinstein) of what could be called the Human Cloning Legalization and Legitimization Act of 2003 (S. 303) . (lifeissues.net)
The cloning "bans" being supported in his article could likewise be called "the Human Cloning Legalization and Legitimazation Acts of 2003" (e.g. (lifeissues.net)
from nationalreview.com Let's call it "stealth human-cloning legalization. (cbc-network.org)

Following the specification of the compartments, an asym-metric cell signal is transmitted at the interface between the two cell populations. (biologists.com)

A number of celltypes come from mesenchymal stem cells, includingchondrocytes, which produce cartilage. (cellmedicine.com)
Comparative analysis of human induced pluripotent stem cell-derived mesenchymal stem cells and umbilical cord mesenchymal stem cells. (reprocell.com)

Those were spindle removal, donor cell fusion, and cytoplast activation. (news-medical.net)

Differentiation of stem cells is known be triggered by various growth factors and regulatory molecules. (justia.com)
The use of human telomerase reverse transcriptase-immortalized bone marrow mesenchymal stromal cells (hTERT-BMSCs) as vehicles to deliver antinociceptive galanin (GAL) molecules into pain-processing centers represents a novel cell therapy strategy for pain management. (hindawi.com)
The use of cell lines as "biological minipumps" to chronically deliver antinociceptive molecules into the pain-processing centers of the spinal cord represents a newly developed technique for the treatment of pain [ 3 ]. (hindawi.com)

Before the first occurs, all of the chromosomes are duplicated just as they are in body cell reproduction, but what happens next is different: the two duplicated strands remain attached to each other as the members of each chromosome pair move alongside each other. (learner.org)

Induced Pluripotent Stem Cells (iPSCs) are cells derived from non-pluripotent cells, such as adult somatic cells, that are genetically manipulated so as to return to an undifferentiated, pluripotent state. (asu.edu)
Research on iPSCs, initiated by Shinya Yamanaka in 2006 and extended by James Thompson in 2007, has so far revealed the same properties as embryonic stem cells (ESCs), making their discovery potentially very beneficial for scientists and ethicists alike. (asu.edu)
The recent development of induced pluripotent stem cells (iPSCs) and related technologies has caught the attention of scientists, activists, politicians, and ethicists alike. (asu.edu)
IPSCs gained immediate international attention for their apparent similarity to embryonic stem cells after their successful creation in 2006 by Shinya Yamanaka and in 2007 by James Thompson and others. (asu.edu)
The advent of iPSCs has opened up the possibility to graft patient-specific cells which most likely would circumvent the need for immunosuppression. (lu.se)

Till's work with stem cells in bone marrow, which produces the body's blood cells, helped form the field of modern hematology, a medical discipline that focuses on diseases related to the blood. (asu.edu)
Long before the controversy emerged over human embryonic stem cells, scientists and doctors began using first-generation stem cells from adult bone marrow. (eppc.org)

These cells have been sought after as potential therapies for diseases ranging from heart disease to Parkinson's to cancer. (news-medical.net)
Because the early stem cells have the ability to become any one of the hundreds of different kinds of human cells, scientists are working on research using these cells with the aim of creating therapies to treat a variety of diseases. (jewishvaluesonline.org)
We now see a patent landscape where stem cell technologies and related therapies can, with very few exceptions, be protected via patents, provided the appropriate form of claim wording is used. (schlich.co.uk)
The data presented in this thesis may serve as valuable resources to help optimize future cell replacement therapies for patients suffering from PD. (lu.se)

Cloning is commonly used to amplify DNA fragments containing whole genes, but it can also be used to amplify any DNA sequence such as promoters, non-coding sequences and randomly fragmented DNA. (wikipedia.org)

Beyond this scientific interest, the commercial concern in animal cloning focuses on replicating large numbers of genetically identical animals, especially those derived from a progenitor that has been modified genetically. (who.int)
Adult stem cells can be used to accelerate bone or tendon healing , and they can induce cartilage progenitor cells to produce a better matrix and repair cartilage damage . (thefutureofthings.com)
The first part of the thesis (Paper I, II, III) shows the development and improvement of a hESC-based system of for virus-mediated direct reprogramming of human glial progenitor cells into both induced dopaminergic neurons (iDANs) and GABAergic interneurons. (lu.se)

It was clear that a definitive experiment required the replacement of a zygote nucleus by a somatic cell nucleus, asking whether the somatic nucleus could functionally replace the zygote nucleus by eliciting normal development of the enucleated recipient egg ( Fig. 1 )? (biologists.com)

Coined by Herbert J. Webber, the term clone derives from the Ancient Greek word κλών (klōn), twig, which is the process whereby a new plant is created from a twig. (wikipedia.org)
The process of differentiation in stem cells involves selective development of immature cells to committed and fully mature cells of various lineages. (justia.com)
It is critical that this orderly and precise process happens every time a body cell divides. (learner.org)
After that first body cell forms, body cell reproduction is the process by which animals grow and develop, and by which new cells are produced and worn-out cells replaced. (learner.org)
In an elegant process called meiosis, each sex cell receives one member of each chromosome pair-23 total. (learner.org)
The process involves two cell divisions. (learner.org)
Somatic cells are cells that have gone through the differentiation process and are not germ cells. (asu.edu)
This continuous process allows a population of cells to increase in number or maintain its numbers. (cellmedicine.com)
Differentiation -The process whereby an unspecialized early embryonic cell acquires the features of a specialized cell such as a heart, liver, or muscle cell. (cellmedicine.com)
Schematic diagram of the somatic cloning process. (biomedcentral.com)
The technology of stem cell induced-gamete production will greatly simplify the generation process, and consequently improve the generation efficiency of genetically modified animals. (bvsalud.org)
A comparable process of short range interaction between dorsal and ventral cells leads to formation of a growth control center at the D/V compartment boundary. (biologists.com)
This process requires a signal between dorsal and ventral cells which leads to localized expression of a signaling molecule at the compart-ment boundary. (biologists.com)

Using a genetically engineered mouse model, we generated mammary-specific Dusp4 -deleted primary epithelial cells to investigate the necessary conditions in which DUSP4 loss may drive breast cancer oncogenesis. (biomedcentral.com)

Scientists have used cloning technology to transform human skin cells into embryonic stem cells, an experiment that may revive the controversy over human cloning. (nationalrighttolifenews.org)
The method described on Wednesday by Oregon State University scientists in the journal Cell, would not likely be able to create human clones, said Shoukhrat Mitalipov, senior scientist at the Oregon National Primate Research Center. (nationalrighttolifenews.org)
But they are also less equipped to produce every cell type of the body and less able to reproduce themselves indefinitely, which makes them less appealing to scientists interested in basic research. (eppc.org)
In July 2005, for example, scientists announced that they had engineered adult mouse stem cells into usable mouse eggs, a technique that might one day allow for the creation of human eggs from ordinary human cells. (eppc.org)

The stem cells in storage at Hwang's laboratories at the university were all derived from the fertility clinic MizMedi's blastocysts, which were generated by in vitro fertilization . (blogspot.com)
Cell culture -Growth of cells in vitro on an artificial medium for experimental research. (cellmedicine.com)
Embryonic stem cell line -Embryonic stem cells, which have been cultured under in vitro conditions that allow proliferation without differentiation for months to years. (cellmedicine.com)
Cells are collected from donor (a) and cultured in vitro (b). (biomedcentral.com)
As a result, an integrative (both cell-level and multicellular) view is essential, and current regulations need to be revisited (see Supplementary Fig. 1 overviewing the Comprehensive in Vitro Pro-arrhythmia Assay 5 Concept). (nature.com)

Only two of Hwang's 11 claimed stem-cell lines existed when he submitted his 2005 paper to the journal, Science, the university said on Dec. 23. (blogspot.com)

In animal cloning, researchers remove the nucleus - the part of the cell that contains the DNA - from a fertilized egg and replace it with the nucleus of a somatic cell, e.g. a skin cell. (innovativegenomics.org)
The stem cells could be studied in the laboratory to help researchers understand what goes wrong in diseases like these. (eurostemcell.org)
The researchers stopped well short of creating a human clone. (nationalrighttolifenews.org)
US researchers have reported a breakthrough in stem cell research, describing how they have turned human skin cells into embryonic stem cells for the first time. (nationalrighttolifenews.org)

Retrieved on December 04, 2023 from https://www.news-medical.net/life-sciences/Cloning-Human-Cells.aspx. (news-medical.net)
Stability of Imprinting and Differentiation Capacity in Naïve Human Cells Induced by Chemical Inhibition of CDK8 and CDK19. (axonmedchem.com)

In the nucleus of each body cell, DNA is organized into chromosomes, which exist as chromosome pairs - with each member of a pair carrying the same set of genes. (learner.org)
Cells end up being different from one another because different genes within the genome direct their development. (learner.org)
The very important question to be addressed at that time was whether all cell types in the body have the same set of genes. (biologists.com)
DUSP4 alterations lead to hyperactivation of MAPK signaling in many cancers, including breast cancer, which often harbor mutations in cell cycle checkpoint genes, particularly in TP53. (biomedcentral.com)
Interestingly, replication stress in Brca2-null cells activates p53 and the expression of its target genes, including senescence-inducing Ink4/Arf. (biomedcentral.com)
Variation of DNA methylation on the IRX1/2 genes is responsible for the neural differentiation propensity in human induced pluripotent stem cells. (reprocell.com)
B)The use of BACs reduces the frequency with which specific genes will be cut within the coding region by restriction enzymes and divided up among two or more clones. (easynotecards.com)
After epidermal injury, barrier repair requires activation of many wound response genes in epidermal cells surrounding wound sites. (sdbonline.org)

In terms of chromosome pairs, all animals of the same type are alike - that is, their body cells contain the same number and arrangement of chromosomes. (learner.org)
Then, each chromosome is passed to each daughter cell. (learner.org)

Pancreatic Differentiation of Stem Cells Reveals Pathogenesis of a Syndrome of Ketosis-Prone Diabetes. (reprocell.com)
First, we utilized single cell sequencing to dissect the differentiation of stem cells to midbrain dopaminergic neurons. (lu.se)

Anatomy63

Organisms18

Diseases16

Chemicals and Drugs46

Analytical, Diagnostic and Therapeutic Techniques and Equipment41

Phenomena and Processes82

Disciplines and Occupations1

Technology, Industry, Agriculture2

Information Science3

Embryos31

Embryo32

SCNT16

Reproductive10

Therapeutic15

Organism14

Creation of cloned human1

Genetic12

Organisms9

Tissues20

Tissue20

Oocyte4

Humans5

Dolly4

Transplantation5

Identical to the donor1

Asexual1

Gene7

Molecular8

Embryonic stem-cel5

Differentiate6

Procedure2

Fetal1

METHODS6

Developmental2

Species6

Tadpoles2

Epigenetic1

Egg's2

Genomes2

Gestation2

Adult cell6

Legalization3

Populations1

Mesenchymal stem2

Donor cell1

Molecules3

Occurs1

IPSCs5

Bone marrow2

Therapies4

Commonly1

Progenitor3

Zygote1

Process13

Epithelial1

Scientists4

Vitro5

Stem-cell lines1

Researchers4

Human Cells2

Genes8

Chromosome2

Differentiation of stem cells2