Cell AgingCell NucleusCyclin-Dependent Kinase Inhibitor p16Telomerebeta-GalactosidaseAging, PrematureCyclin-Dependent Kinase Inhibitor p21TelomeraseBiological ProcessesTumor Suppressor Protein p53AgingTelomere ShorteningCells, CulturedFibroblastsCell ProliferationDNA DamageSignal TransductionOxidative StressRetinoblastoma ProteinReactive Oxygen SpeciesApoptosisCell Line, TumorNucleus AccumbensCell CycleEndothelial CellsThalamic NucleiSolitary NucleusGene Expression RegulationTOR Serine-Threonine KinasesTime FactorsCell LineRNA InterferenceUp-RegulationCell DivisionRNA, Small InterferingCochlear NucleusHistonesPhenotypeDown-RegulationBlotting, WesternRaphe NucleiActive Transport, Cell NucleusStem CellsCerebellar NucleiSeptal NucleiDNA-Binding Proteinsp38 Mitogen-Activated Protein KinasesPlant LeavesMice, Inbred C57BLArcuate NucleusCaudate NucleusCell Cycle ProteinsParaventricular Hypothalamic NucleusReverse Transcriptase Polymerase Chain ReactionImmunohistochemistryMice, KnockoutRNA, MessengerTransfectionEndothelium, VascularCell DifferentiationDose-Response Relationship, DrugFlow CytometryGene Expression Regulation, NeoplasticAtherosclerosisSuprachiasmatic NucleusRed NucleusTrigeminal NucleiBiological MarkersSubthalamic NucleusSupraoptic NucleusEnzyme ActivationCytoplasmNuclear ProteinsPhosphorylationNeuronsGene Expression Regulation, PlantCell Nucleus ShapeRats, Sprague-DawleyMolecular Sequence DataOlivary NucleusEthylenesChlorophyllMutationArabidopsisTranscription FactorsCell Transformation, NeoplasticTrigeminal Nucleus, SpinalModels, BiologicalTumor Suppressor Protein p14ARFVentral Thalamic NucleiBrain StemLongevityCell Cycle CheckpointsTumor Suppressor ProteinsIntralaminar Thalamic NucleiPlant ProteinsMicroinjectionsArabidopsis ProteinsBasal Nucleus of MeynertAmino Acid Sequence