Nucleus cell size. Medical search. Frequent questions

Given its fundamental and universal functional roles in protecting the DNA and regulating the exchange of information and control machinery between genome and cytoplasm, one might ask the question: why are there so many ways to build and remodel a nucleus? (europa.eu)
Histologically, ALCL is characterized by sheets of large pleomorphic cells with abundant cytoplasm, horseshoe- or wreath-shaped nuclei, and multiple prominent nucleoli. (medscape.com)
plump polyhedral nevus cells: Abundant cytoplasm is filled with pigment and has a small round to oval nucleus with bland appearance. (aao.org)
slender spindle nevus cells (Fig 12-16): The cytoplasm contains scant pigment and a small, dark, elongated nucleus. (aao.org)
balloon cells: Abundant, foamy cytoplasm lacks pigment and has a bland nucleus. (aao.org)
Histologically, a melanocytoma is composed of large polyhedral cells with small round to oval nuclei and abundant cytoplasm. (aao.org)
Epithelioid melanoma cells resemble epithelium because of their abundant eosinophilic cytoplasm and enlarged round to oval nuclei. (aao.org)
Note the balloon cells (arrowheads) with abundant foamy cytoplasm. (aao.org)
The cell body, also called the soma, contains the neuron's nucleus and most of its cytoplasm, along with molecular machinery for building and transporting proteins critical to the cell's function. (brainfacts.org)
This 96-well plate has images of cytoplasm to nucleus translocation of the transcription factor NFκB in MCF7 (human breast adenocarcinoma cell line) and A549 (human alveolar basal epithelial) cells in response to TNFα concentration. (broadinstitute.org)
Histologically, the lesions exhibit a lobular growth pattern and are composed of cellular nodules with the classic appearance of SFT, patternless distribution of both oval and spindle shaped cells with uniform spindled nuclei and scant cytoplasm in a variably collagenous stroma and branched, often thick walled, hemangiopericytoma-like vessels ( Ann Diagn Pathol 2018;34:142 ) admixed with adipocyte rich lobules ( Arch Pathol Lab Med 1999;123:941 ). (pathologyoutlines.com)
For this reason they are not included in the daughter cells' nuclei, thus remaining in the cytoplasm of interphase cells [5, 10, 16, 35]. (bvsalud.org)

The mitochondria of the myofibrils were numerous, spherical, small in size and regularly arranged between the myofibrils. (bmj.com)
Mitochondria are known as the powerhouse of a cell because they are responsible for generating energy in the form of adenosine triphosphate (ATP). (annique.com)
Sometimes Mitochondria don't work as well as they should due to another disease or condition in the cell - this is called Mitochondrial dysfunction. (annique.com)
Positively charged molecules are usually cell membrane permeable and accumulate in mitochondria. (dojindo.com)
Mitochondria exist in most eukaryotic cells and play a very important role in oxidative metabolism by generating ATP as an energy source. (dojindo.com)
The average number of mitochondria per cell is from 100 to 2,000. (dojindo.com)
Although the typical size is about 0.5-2 mm, the shape, abundance, and location of mitochondria vary by cell type, cell cycle, and cell viability.Therefore, visualization of mitochondra is important. (dojindo.com)
MitoRed and Rh123 readily pass through cell membranes and accumulate in mitochondria. (dojindo.com)
Loading controls can be general whole cell proteins or specific markers for subcellular fractions (e.g. nucleus, mitochondria, membrane). (novusbio.com)
Genes are contained in chromosomes in the cell nucleus and mitochondria. (msdmanuals.com)
DNA (deoxyribonucleic acid) is the cell's genetic material, contained in chromosomes within the cell nucleus and mitochondria. (msdmanuals.com)

PL: nuclei) is a membrane-bound organelle found in eukaryotic cells. (wikipedia.org)
Eukaryotic cells usually have a single nucleus, but a few cell types, such as mammalian red blood cells, have no nuclei, and a few others including osteoclasts have many. (wikipedia.org)
In eukaryotic cells the genetic material is surrounded by a membrane system called the nuclear envelope (NE). (brookes.ac.uk)
The Nuclear Envelope is a hallmark of eukaryotic cells. (brookes.ac.uk)

However, in most cases there are specific features that may aid in differentiating small reactive from non-reactive lymphocytes including the round shape of the nucleus, the absence of visible nucleoli and the presence of fine clumped chromatin. (cytojournal.com)
Large cell lymphoma and leukemia cells tend to have large size nuclei, less mature chromatin, and visible nucleoli with and without cytoplasmic vacuoles. (cytojournal.com)
Spindle-A melanoma cells have slender, elongated nuclei with small nucleoli. (aao.org)
Their nuclei have a conspicuous nuclear membrane, very coarse chromatin, and large nucleoli. (aao.org)
The tumor cells appeared spindled with normochromatic, small nuclei and indistinct nucleoli (Figure 7 ). (upmc.edu)

Electron microscopy demonstrated a poorly differentiated mesenchymal tumor with a multifocal giant cell component and evidence of neurosecretory-granules. (hindawi.com)
ALCL was recognized in 1985, when tumor cells consistently demonstrated labeling by the monoclonal antibody Ki-1, a marker later shown to recognize the CD30 antigen. (medscape.com)
When this type of tumor grows to a significant size, it may extend beyond its site of origin (ie, from the choroid to the ciliary body and vice versa). (aao.org)
however, a tumor consisting entirely of spindle-A cells is considered a nevus. (aao.org)
The tumor contained variably sized cystic spaces including large dilated ones filled with blood (Figure 6 ). (upmc.edu)
The tumor cells were focally embedded in a myxochondroid and osteoid-like matrix (Figures 8 and 9 ) with scattered areas of dystrophic calcification (Figure 8 ). (upmc.edu)
The tumor was penetrated by capillary-sized vessels and intermixed with scattered osteoclast-like giant cells (Figure 11 ). (upmc.edu)
Clear cell type renal cell carcinoma is a malignant tumor that can metastasize to many locations, but unusually spreads to thyroid. (scirp.org)
Clear cell renal carcinoma (CCRC) is a tumor with great metastatic capacity, although the presence of metastases in the thyroid gland is very uncommon. (scirp.org)
Intraoperatively, a large cervical tumor was observed with greater size of the right lobe, measuring approximately 12 × 10 cm and moving the trachea to the left. (scirp.org)
Medulloblastoma is defined by the World Health Organization (WHO) as "an embryonal neuroepithelial tumor arising in the cerebellum or dorsal brainstem, presenting mainly in childhood and consisting of densely packed small round undifferentiated cells with mild to moderate nuclear pleomorphism and high mitotic count. (medscape.com)
Objective: To investigate the cytomorphological and immunocytochemical features of tumor cells in the ascites of ovarian plasmacytoma (SOC). (bvsalud.org)

In spindle-B melanoma cells, coarse, granular chromatin and plump, large nuclei are seen. (aao.org)

FISH is targeted toward specific abnormalities, and results can be evaluated in an automated fashion on interphase nuclei, allowing for examination of more cells than a traditional karyotype. (medscape.com)

The Pap test is a cervical cancer prevention test that tracks preneoplastic changes in cervical epithelial cells. (mdpi.com)
The duct (clear zone at center) is lined by highly polarized epithelial cells with dark nuclei at the base. (cellimagelibrary.org)

Nucleus with chromosomes, DNA molecule (double helix), telomere and gene (length of DNA that codes for a specific protein). (istockphoto.com)
The genes within these chromosomes are structured in such a way to promote cell function. (wikipedia.org)
Although the interior of the nucleus does not contain any membrane-bound subcompartments, a number of nuclear bodies exist, made up of unique proteins, RNA molecules, and particular parts of the chromosomes. (wikipedia.org)
In vascular plants, the principal generation phase is the large, dominant, nutritionally-independent sporophyte , which is diploid with two sets of chromosomes per cell . (newworldencyclopedia.org)
In non-vascular plants, the principal generation phase is often the gametophyte , which is haploid with one set of chromosomes per cell. (newworldencyclopedia.org)
In humans, somatic (nongerm) cell nuclei normally have 46 chromosomes in 23 pairs. (msdmanuals.com)
A karyotype illustrates the full set of chromosomes in a person's cells. (msdmanuals.com)
Germ cells (egg and sperm) divide through meiosis, which reduces the number of chromosomes to 23-half the number in somatic cells. (msdmanuals.com)
Except for certain cells (for example, sperm and egg cells and red blood cells), the cell nucleus contains 23 pairs of chromosomes. (msdmanuals.com)
Such structures are a result of chromosome fragments or entire acentric chromosomes which are lost during a cell division. (bvsalud.org)

Accurate results of cell nuclei segmentation are often adapted to a variety of applications such as the detection of cancerous cell nuclei and the observation of overlapping cellular events occurring during wound healing process in the human body. (hindawi.com)
A cell nuclei segmentation algorithm incorporating unsupervised color clustering, morphological operations, and local thresholding has been proposed to distinguish the cancerous and noncancerous areas in histologically stained images and then segment the clustered cell nuclei [ 3 ]. (hindawi.com)
We will test if causing nuclei to become bigger confers cancerous growth on those cells, and conversely, if shrinking cancer cell nuclei reduces severity of the disease by slowing cell growth and metastatic potential. (uwyo.edu)

However, as the result of recent advancements in microscopic imaging technology and computational image processing techniques [ 1 ], there has been significant growth of research towards translational computational systems that can detect, analyze, classify, and quantify cell nuclei from microscopic images. (hindawi.com)
Finally, we describe deep-learning methods well-suited for 3D analysis of nuclei and classify them according to their level of usability for biologists. (brookes.ac.uk)

A nucleus may have a complex internal structure, with several types of neurons arranged in clumps (subnuclei) or layers. (wikipedia.org)
Despite having no brain or neurons and being just one giant goopy cell, these slime molds keep defying our expectations. (sciencefriday.com)
Neurons come in many shapes and sizes, but most have some basic features. (brainfacts.org)
Dendrites, the arms extending from the cell body, receive signals from other neurons at junctions called synapses. (brainfacts.org)
Neurons come in a broad range of shapes and sizes, but all of them have a cell body , dendrites , and an axon . (brainfacts.org)
Dendrites are branched projections that extend from the cell body and collect incoming signals from other neurons. (brainfacts.org)
Neurons are associated with support cells called glia . (brainfacts.org)
These cells (neurons) communicate with each other releasing neurotransmitters into the gaps or synapses between the nerve cells. (drug-addiction-support.org)
There are two types of cells that comprises the nervous system-glial cells (often called glia) and nerve cells (often called neurons). (drug-addiction-support.org)
Neurons are the cells that communicate with other cells. (drug-addiction-support.org)

Clifford Brangwynne (left), assistant professor of chemical and biological engineering, worked with postdoctoral researcher Ming-Tzo Wei and interdisciplinary collaborators to develop a method for looking at watery structures inside cells. (princeton.edu)
The cell body contains structures such as the nucleus. (brainfacts.org)
His research has focused specifically on autophagy activity, which is an intracellular degradation process that allows cells to recycle damaged components to generate energy and provide building blocks to create new cellular structures. (annique.com)
Various activities and structures of a cell can be targeted for staining with fluorescent compounds (Fig. 1). (dojindo.com)
CT scan images were also obtained to evaluate size and relation with other structures ( Figure 2 ). (scirp.org)

The nucleus contains nearly all of the cell's DNA, surrounded by a network of fibrous intermediate filaments called the nuclear matrix, and is enveloped in a double membrane called the nuclear envelope. (wikipedia.org)
14 Embedded within the inner membrane, various proteins bind the intermediate filaments that give the nucleus its structure. (wikipedia.org)
Every eukaryote has a nucleus, a double lipid membrane-bound compartment that encapsulates the genome, but almost every nucleus is different - in shape, size, molecular composition, spatial organisation, and dynamics through the cell cycle. (europa.eu)
Anaplastic large cell lymphomas (ALCLs) are distinguished from other lymphomas by their anaplastic cytology and constant membrane expression of the CD30 antigen (an activation marker for B or T cells). (medscape.com)
Since it has an amine-reactive succinimidyl group, fluorescein derived from CFSE can covalently bond to proteins or other amino groups in the cell or on the cell membrane. (dojindo.com)

In addition, cytoplasmic vacuoles are not uncommon in large cell lymphomas involving body cavities. (cytojournal.com)
The cytoplasmic melanin content in melanoma cells can vary considerably. (aao.org)
Also, DM induced histopathological alterations such as cytoplasmic vacuolization and degeneration in nuclei, congestion, an enlargement of the blood vessels and lymphocytes infiltration in the liver. (scialert.net)

Having multiple nuclei seems to make it easier for bigger cells to properly manage their relatively large cellular bodies. (listverse.com)

The nucleus maintains the integrity of genes and controls the activities of the cell by regulating gene expression. (wikipedia.org)
The bacterial cell is able to control many protein-coding genes (green lines at bottom) with relatively few controls (yellow and purple lines). (creation.com)
The genes in cells carry the hereditary information that is received from a person's parents. (cancer.gov)
The EMD and LMNA genes provide instructions for making proteins that are components of the nuclear envelope, which surrounds the nucleus in cells. (medlineplus.gov)
The nuclear envelope regulates the movement of molecules into and out of the nucleus, and researchers believe it may play a role in regulating the activity of certain genes. (medlineplus.gov)
Twenty-two of the pairs, chromosome numbers 1 to 22, the autosomes, are normally homologous (identical in size, shape, and position and number of genes). (msdmanuals.com)

Similar systems regulate cell growth in humans and frogs, and frog research has informed a variety of human diseases, including cancer. (uwyo.edu)
Discoveries about nuclear size control in frogs will thus also hold true in humans, producing useful and important information for the cancer community. (uwyo.edu)
Part of the work in the Levy lab is focused on translating our findings about nuclear size control in frogs to humans. (uwyo.edu)

Knockout Validated Western Blot showing lysates of HeLa parental cell line and LC3B knockout HeLa cell line (KO) untreated (-) or treated (+) with 50 uM Chloroquine. (novusbio.com)
A specific band was detected for LC3B at a molecular weight of approximately 15 kDa in the parental HeLa cell line, but is not detectable in the knockout cell line. (novusbio.com)

The primary tasks involved in the analysis of histologically stained tissue sections are cell nuclei counting, detecting abnormal cell nuclei, and the presence of antigens within the target cells. (hindawi.com)
Sixty percent of cases express 1 or more T-cell antigens (CD3 + , CD43, or CD45RO). (medscape.com)

plump fusiform dendritic nevus cells: Morphology is intermediate between that of plump polyhedral and slender spindle. (aao.org)
Numerous dendritic cells (DCs) with euchromatic nuclei, and multiple and long dendrites, were seen among the myofibrils. (bmj.com)

We aimed for addressing the role of FasL expression in human intervertebral disc degeneration (IDD) and immune privilege in terms of the interaction between NP cells and immunocytes via the FasL-Fas machinery. (medsci.org)
In the treated group, the muscle fibres had a relatively uniform size with occasional fibres showing partial degeneration. (bmj.com)

This size selectively allows the passage of small water-soluble molecules while preventing larger molecules, such as nucleic acids and larger proteins, from inappropriately entering or exiting the nucleus. (wikipedia.org)
I'm using cell and molecular biology techniques, biochemistry as well as microscopy to characterise the plant SUN proteins. (brookes.ac.uk)
This includes finding out what other proteins the SUNs bind to and what functions they have during cell division. (brookes.ac.uk)
The most commonly stained cell components are cell membranes, proteins, and nucleotides. (dojindo.com)
These compounds are neutral molecules that pass through cell membranes and covalently conjugate with cell proteins. (dojindo.com)

The cell nucleus contains nearly all of the cell's genome. (wikipedia.org)
The previously proposed distinction between 'holoploid' (C) and 'monoploid' (Cx) genome size covers the most frequent states of plant and animal nuclear genomes. (cas.cz)
Each eukaryotic cell contains a nucleus that houses its genome. (europa.eu)

Effect of downsampling (2x2, 8x8, 16x16, 32x32) on a normalized nuclei image from the KDSB18 dataset (left to right, respectively). (medium.com)

This is an important question because nuclei in cancer cells are usually inappropriately enlarged, a change that pathologists use to diagnose and stage disease. (uwyo.edu)

Variation in adipocyte size and multivacuolated small cells with nuclear scalloping (lipoblast-like cells) may be evident focally ( Arch Pathol Lab Med 1999;123:941 ). (pathologyoutlines.com)
The interstitial nuclei of the human anterior hypothalamus: an investigation of sexual variation in volume and cell size, number and density. (bvsalud.org)

Despite their close apposition around much of the nucleus, the two membranes differ substantially in shape and contents. (wikipedia.org)
The vertebrate brain contains hundreds of nuclei, which vary in shape and size. (wikipedia.org)
A change in the size or shape of the breast. (cancer.gov)
However, many questions remain about how its shape and size are regulated during development, in different tissues or during disease and aging. (brookes.ac.uk)
They are usually found beside the main nucleus and are similar in shape, color, and chromatinic body distribution [14]. (bvsalud.org)

A nucleus in anatomy is a brain structure (plural = nuclei). (wikipedia.org)

small glial cells only have about a few hundred, with large Purkinje cells having around 20,000. (wikipedia.org)

for example, the quantification of total cells and abnormal cells was performed through manual hand counting. (hindawi.com)
While some techniques only perform the task of cell nuclei segmentation and quantification, techniques that are capable of further detecting and classifying abnormal tumors (cell nuclei) that cause various types of cancer have also been proposed. (hindawi.com)
Lobular carcinoma in situ (abnormal cells found in one of the lobes or sections of the breast), which sometimes occurs in women, has not been seen in men. (cancer.gov)
The myofibrils had a relatively similar diameter comparable to that of normal muscle .The degenerated areas were small in size with occasional foci showing loss of banding pattern, and abnormal short bands with thick and hazy Z-lines. (bmj.com)

649 Together, these membranes serve to separate the cell's genetic material from the rest of the cell contents, and allow the nucleus to maintain an environment distinct from the rest of the cell. (wikipedia.org)

In general, hematolymphoid cells manifest as dyshesive cells in cytological specimens. (cytojournal.com)

Non-vascular plants lack these and are restricted to relatively small sizes. (newworldencyclopedia.org)
Small neutral molecules and positively charged molecules can pass through viable cell membranes and remain inside of cells, depending on their reactivity or hydrophilicity. (dojindo.com)
Choosing a loading control that is close in size, but still large or small enough to be easily distinguished from your target protein is crucial. (novusbio.com)
The immunohistochemical study was negative for Thyroid Transcription Factor 1 (TTF-1), although it was not valued for vimentin, cytokeratin 8 and CD10 because of the small size of the lesion that did not allow an adequate study ( Figure 3 ). (scirp.org)
Furthermore, these collaborative research efforts span the widest possible range in terms of company size, from small-size high-tech companies, over mid-size companies with a strong local base, to large, multinational enterprises. (lu.se)

Figure 12-16 Spindle-cell choroidal nevus (between arrows) is composed of slender spindle-shaped cells with thin, homogeneously staining nuclei. (aao.org)

Negatively charged molecules cannot pass through viable cell membranes. (dojindo.com)
Ester can pass through viable cell membranes, where it is hydrolyzed by cellular esterases into a negatively charged molecule under physiological conditions. (dojindo.com)
CFSE is also an ester compound that passes through viable cell membranes. (dojindo.com)
Cell membranes of viable cells are impermeable to these fluorescent dyes,except for the Hoechst dyes, and these dyes can therefore be used as fluorescent indicators of dead cells. (dojindo.com)
Hoechst dyes are positively charged under physiological conditions and can pass through viable cell membranes. (dojindo.com)

The virus, tentatively named Ryukyu virus 1 (RV1), caused apparent CPE on primary kidney cells derived from a Ryukyu flying fox and on our established bat kidney T1 (BKT1) cells, which were derived from the kidney of a horseshoe bat ( Rhinolophus ferrumequinum ) and transformed with expression plasmid DNA encoding the large T antigen of replication origin-defective simian virus 40. (cdc.gov)

The size of the nucleus is correlated to the size of the cell, and this ratio is reported across a range of cell types and species. (wikipedia.org)
Factors were identified that determine nuclear size in two different size frog species. (uwyo.edu)
Nuclei of trophozoites are visible in formalin-fixed material but are usually not sufficiently distinctive for species identification. (cdc.gov)
With the permission of the governor of Okinawa, we caught 1 adult male bat of this species and used its spleen and kidneys to establish primary cell cultures. (cdc.gov)

The segmentation and quantification of cell nuclei are two very significant tasks in the analysis of histological images. (hindawi.com)
In this paper, an automated entropy-based thresholding system for segmentation and quantification of cell nuclei from histologically stained images has been presented. (hindawi.com)
Adapting to robust automated image processing techniques for primary tasks such as cell nuclei segmentation and quantification will not only prove to be time efficient for pathologists, but these techniques will also be capable of producing consistent results. (hindawi.com)
In recent years, numerous image processing techniques have been proposed for cell nuclei segmentation [ 2 ]. (hindawi.com)
K-means clustering is implemented as unsupervised color clustering technique for cell nuclei segmentation in [ 4 ]. (hindawi.com)
Another technique that uses contour detection and contour optimization combined with local gradient information and color deconvolution has been used to detect the optimal threshold values for nuclei segmentation [ 5 ]. (hindawi.com)
Entropic-based thresholding methods for cell nuclei segmentation are proposed by Wang and Gudla et al. (hindawi.com)
An adaptive-attention-window-(AAW-) based cell nuclei segmentation technique that exploits quadtree decomposition is proposed by Ko et al. (hindawi.com)
Nuclei images with their respective segmentation masks. (medium.com)

This ulcerated nodule of localized primary cutaneous CD30+ anaplastic large cell lymphoma is relatively nonspecific in appearance. (medscape.com)
Histologic subtypes of medulloblastoma include: (1) desmoplastic/nodular type, (2) medulloblastoma with extensive nodularity, and (3) large-cell/anaplastic medulloblastoma. (medscape.com)

The effectiveness of the proposed system was tested over 21 histologically stained images containing approximately 1800 cell nuclei, and the overall performance of the algorithm was found to be promising, with high accuracy and precision values. (hindawi.com)
Histologically, posterior uveal melanomas are composed of spindle cells and/or epithelioid melanoma cells (Figs 12-17, 12-18, 12-19). (aao.org)

1 Department of Cell and Developmental Biology and Department of Bioengineering, University of Pennsylvania, 421 Curie Blvd, Philadelphia, PA 19104, USA. (nih.gov)
Bringing together comparative genomics, phylogenetics, quantitative cell biology and experimental evolution in multiple microbial model systems drawn from across the eukaryotic tree, we set out to elucidate the genomic, biophysical and evolutionary factors that determine nuclear dynamics and remodelling - karyodynamics - within the context of cellular architecture and function. (europa.eu)
I am a senior lecturer in Cell Bilogy and a member of the plant biology group. (brookes.ac.uk)
Previous to this I completed my BSc in Cell and Human Biology here at Oxford Brookes University. (brookes.ac.uk)
For a century, the nucleus has been the focus of extensive investigations in cell biology. (brookes.ac.uk)
In the same issue of Science , a second research team from the Shanghai Institute of Biochemistry and Cell Biology reported similar results using a different method for tracking the origins of new liver cells. (nih.gov)

These large molecules must be actively transported into the nucleus instead. (wikipedia.org)
Understanding the molecules and mechanisms that regulate nuclear size in cancer cells will offer novel approaches to cancer diagnosis and treatment that target nuclear size, as well as identify new cancer susceptibility factors associated with altered nuclear size that could aid in prevention. (uwyo.edu)
This liquid scaffolding lets molecules only of certain sizes easily diffuse in and out of the structure, enabling them to perform their vital tasks. (princeton.edu)
At right: An artist's impression of a tighter zoom into the P granule, revealing its structure that it is permeable to molecules only of certain sizes, shown in red. (princeton.edu)
Covalently conjugated molecules can stay in the cell for several weeks. (dojindo.com)
Calcein and BCECF can be converted into electrically neutral molecules by the addition of acetyl or acetoxymethyl groups to their phenolic OH or carboxylic groups, which allows them to freely permeate into the cell. (dojindo.com)

Usually evenly distributed and uniform in size. (cdc.gov)
The majority of adipocytes are uniform, round, univacuolar cells with peripherally located, compressed nuclei. (pathologyoutlines.com)

Bone marrow examination showed the proliferation of hematopoietic cells were active, mainly granulocytes, and immature granulocytes increased. (frontiersin.org)
However, the presence of nevus cells contiguous with a choroidal melanoma on histologic examination provides evidence that melanomas may arise from choroidal nevi. (aao.org)

12 In human cells, the diameter of the nucleus is approximately six micrometres (µm). (wikipedia.org)

FCM analysis found that human NP cells with increased FasL expression resulted in significantly increased apoptosis ratio of macrophages and CD8 + T cells. (medsci.org)

The authors make insights into the regulation of nuclear growth that potentially explain the widely reported correlation between nucleus size and cell size. (nih.gov)
We examined the correlation between nuclear deformation and cell functions such as cell proliferation, transfection and extracellular matrix protein type I collagen production. (cdc.gov)

Researchers speculate that changes in EMD or LMNA could weaken the structure of the nuclear envelope in cells that undergo a lot of mechanical stress, such as skeletal and cardiac muscle cells, making these cells more fragile. (medlineplus.gov)

Some studies have suggested that stem cells can produce new liver cells. (nih.gov)
Zhu and his team found that normal hepatocytes-not stem cells-in zone 2 did the bulk of the work of normal liver maintenance. (nih.gov)

In large cell lymphoma and leukemia cells involvement of body fluid this concept becomes less challenging. (cytojournal.com)
Large cells generally have large nuclei, while smaller cells have smaller nuclei. (uwyo.edu)
We presently know very little about what causes large nuclear size or what the consequences are for the cancer patient. (uwyo.edu)
Diffuse large B-cell lymphoma is the most common histologic subtype of NHL, with ENKTL of the large bowel being less frequent ( 4 ). (frontiersin.org)
However, unlike with plastics, the team's results indicated that the "mesh size," or average size of the gaps between units, is relatively large, three to eight nanometers (billionths of a meter). (princeton.edu)
We expose the case of a patient with clear cell type renal cell carcinoma, thyroid metastasis with a previously known bone metastasis of renal origin and large goiter with compressive symptoms. (scirp.org)

Few DCs, with heterochromatic nuclei, and few and short dendrites appeared between the myofibrils. (bmj.com)

The NMDA receptor has been implicated in many instances of neural plasticity, including estrogen-induced morphological changes of hippocampal pyramidal cells. (jneurosci.org)

Differentiating between low-grade lymphoma and reactive lymphocytes is often difficult by morphology alone as reactive lymphoid cells may acquire activation morphology from being exposed to different cytokines within the body fluid. (cytojournal.com)

Thus, current methods to apply nanotopography to regulate cell behavior are basically empirical. (cdc.gov)
Our study delineated the relationships between focal adhesions, nucleus and cell function and highlighted that the nanotopography could regulate cell phenotype and function by modulating nuclear deformation. (cdc.gov)

Reporting in Developmental Cell, Hara and Merten (2015) apply the use of microfabrication and in vitro analysis in cell-free extracts to the old problem of nuclear size control. (nih.gov)
Another focus of our lab is to analyze early frog development when fertilized frog eggs undergo developmental cell divisions that result in reduced cell and nuclear size. (uwyo.edu)

These results suggest that androgen affects the size of SNB motoneurons by influencing their expression of the NMDA receptor, and therefore the response of the motoneurons to endogenous glutamate. (jneurosci.org)
Specifically, we want to determine how nuclear size affects cancer cell growth by directly altering nuclear size in human cells grown in a dish. (uwyo.edu)
We will determine what factors regulate these changes in nuclear size and how altering nuclear size in frog embryos affects their development. (uwyo.edu)
Although nanotopography has been shown to be a potent modulator of cell behavior, it is unclear how the nanotopographical cue, through focal adhesions, affects the nucleus, eventually influencing cell phenotype and function. (cdc.gov)

A popular technique in the realm of image processing known as region growing is combined with a graph-cuts-based algorithm that incorporates Laplacian of Gaussian (LoG) filtering to detect cell nuclei [ 8 ]. (hindawi.com)
tetrazolium salts detect dehydrogenase activity of viable cells. (dojindo.com)
Fluorescent staining using CTC is another method used to detect viable bacterial cells. (dojindo.com)
In addition, because the probe size is much smaller than the resolution provided by the banding pattern in karyotype, FISH can detect cryptic abnormalities not revealed by conventional karyotype. (medscape.com)

The evolution of this vascular tissue allowed for an early dominance of these plants on land (first appearing 430 million years ago, during the Silurian period), giving them the ability to transport water and dissolved minerals through specialized strands of elongated cells that run from the plant root to the tips of the leaves . (newworldencyclopedia.org)
Further work identified a specific cell-signaling pathway that appeared to drive zone 2 liver cells to repopulate damaged tissue. (nih.gov)

HGPIN is characterized by architecturally benign prostatic acini and ducts lined with atypical cells whose morphologic, histochemical, immunohistochemical, and genetic changes are similar to those of prostate cancer. (medscape.com)

The overall goal of this research is to elucidate how nuclear size is regulated during embryogenesis as well as the function of proper nuclear size control in cell growth and development. (uwyo.edu)

The size of bacteria and viruses. (mathgoodies.com)
Bacteria: occasionally red blood cells. (cdc.gov)

Male breast cancer is a disease in which malignant (cancer) cells form in the tissues of the breast. (cancer.gov)
Vascular plants have water-carrying tissues, enabling the plants to become a larger size. (newworldencyclopedia.org)
Depending on the size and location of the nevus, it may exert nonspecific effects on adjacent ocular tissues. (aao.org)

Anatomy23

Organisms1

Analytical, Diagnostic and Therapeutic Techniques and Equipment1

Phenomena and Processes6

Information Science1

Health Care1

Cytoplasm12

Mitochondria11

Eukaryotic cells4

Nucleoli5

Tumor12

Chromatin1

Interphase1

Epithelial2

Chromosomes10

Cancerous3

Classify2

Neurons10

Structures5

Membrane5

Cytoplasmic3

Bodies1

Genes6

Humans3

HeLa2

Antigens2

Dendritic2

Degeneration2

Proteins5

Genome3

Dataset1

Inappropriately1

Variation2

Shape5

Anatomy1

Glial1

Abnormal4

Cell's genetic material1

Specimens1

Small5

Arrows1

Membranes5

Horseshoe1

Species4

Segmentation9

Anaplastic2

Histologically2

Biology6

Molecules6

Uniform2

Examination2

Diameter1

Significantly1

Correlation2

Cardiac1

Stem2

Large6

Dendrites1

Morphological1

Morphology1

Regulate cell2

Developmental Cell2

Affects4

Detect4

Tissue2

Immunohistochemical1

Nuclear size control1

Bacteria2

Tissues3