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  • compound
  • The most active were 2-cyclopentylamino- N 6 -cyclopentyladenosine (compound NA42) and 2-cyclopentylamino- N 6 -cyclopentyladenine (compound NA134), with the nucleobase an order of magnitude more potent than the nucleoside, at 26 ± 4 nM. (asm.org)
  • archaea
  • The BAT family consists of 5 TMS proteins from bacteria and archaea. (tcdb.org)
  • These proteins are derived from phylogenetically divergent bacteria and archaea, and B. subtilis, E. coli, S. coelicolor and A. fulgidus have multiple paralogues. (tcdb.org)
  • Peptides
  • In this study, we designed and characterized IL-22 derived peptides at protein interface regions: several sequences revealed able to interfere with the protein complex with IC50 in the micromolar range as evaluated through Surface Plasmon Resonance (SPR) experiments. (cnr.it)
  • Synthesis of small molecules, modified peptides and nucleobase-decorated peptides. (cnr.it)
  • amino acids
  • A splice variant (SLC43A3_2), encoding a protein with 13 additional amino acids in the first extracellular loop, is also expressed but its function is unknown. (aspetjournals.org)
  • compounds
  • One group of heterocyclic nitrogen compounds, the nucleobases and their degradation products, has been identified in several soils as representing on average 3% of total nitrogen ( Cortez and Schnitzer, 1979 ). (plantcell.org)
  • It appears plausible that, to use these compounds as nitrogen source, specialized transport mechanisms are present in plants. (plantcell.org)
  • mechanism
  • All of these are linked through an expanding network for development and application of existing and novel technologies to study structure, function, ligand recognition, molecular mechanism, dynamics and multidimensional relationships of membrane proteins, other drug targets and molecular markers of health and disease. (openmedscience.com)
  • The drugs transported are generally cationic, and a simple cation antiport mechanism involving the conserved Glu-14 has been proposed ( Yerushalmi and Schuldiner, 2000 ). (tcdb.org)
  • translocation
  • By coupling the inward transport of Na + down its electrochemical gradient to the translocation of I - against its electrochemical gradient, NIS avidly concentrates I - in the thyroid. (pnas.org)
  • expression
  • Protein Expression and Purification, 5 (2). (kent.ac.uk)
  • Protons are cosubstrates in allantoin transport by AtUPS1, as demonstrated by expression in Xenopus laevis oocytes. (plantcell.org)
  • Further studies are required to clarify the nature of this inhibition, but the COS-1 expression system appears to be a useful tool for the possible identification of important regulatory proteins. (kent.ac.uk)
  • "Global analysis of protein expression in yeast. (tcdb.org)
  • However, diet composition affected OXPHOS in the skeletal muscle to a greater extent than in the liver: most of genes upregulated under starvation presented higher expression among fish fed a high carbohydrate/low protein diet. (biomedcentral.com)
  • Our findings indicate that the expression of coenzyme Q-binding protein (COQ10), cytochrome c oxidase subunit 6A2 (COX6A2) and ADP/ATP translocase 3 (SLC25A6) in the liver, and cytochrome c oxidase subunit 5B isoform 1 (COX5B1) in the liver and the skeletal muscle, are sensitive markers of the nutritional condition that may be relevant to assess the effect of changes in the feeding regime and diet composition on fish farming. (biomedcentral.com)
  • Expression proteo-mic studies are screening for differences in protein patterns between tumor and control tissues. (americorpshealth.biz)
  • biochemical
  • Hons) degree in Biomedical Chemistry and a Ph.D. in Chemistry, industrial experience and extensive academic research, teaching, supervisory, publishing, refereeing and organisational experience in structure-function studies of membrane proteins and other drug targets using a wide range of chemical, biochemical, biophysical, molecular imaging and computational techniques. (openmedscience.com)
  • Antibody
  • If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production , custom recombinant protein production or custom antibody production . (mybiosource.com)
  • structural
  • The reciprocal opening and closing of these cavities is synchronized by the inverted repeat helices 3 and 8, providing the structural basis of the alternating access model for membrane transport. (ku.dk)
  • recognition
  • We propose an additional role for PRRs in which they act upon CO protein to promote flowering, directly coupling information on light exposure to the timekeeper and allowing recognition of LDs. (labome.org)
  • allantoin
  • Transport of 14 C-labeled allantoin by AtUPS1 in yeast exhibited saturation kinetics ( K m ∼ 52 μM), was dependent on Glc and a proton gradient, and was stimulated by acidic pH. (plantcell.org)
  • AtUPS1 transports uric acid and xanthine, besides allantoin, but not adenine. (plantcell.org)
  • Genes
  • Transfecting COS-1 cells with opossum kidney cDNA fractions resulted in similar to 70% inhibition of hypoxanthine influx suggesting the possible presence of genes within the library that act as apparent inhibitors of hypoxanthine transport. (kent.ac.uk)