The 2018 Nucleic Acids Research database issue features several papers from NCBI staff that cover the status and future of databases including CCDS, ClinVar, GenBank and RefSeq. (nih.gov)
Curation1
They include Bioinformatics, an official journal of ISCB, Database: The Journal of Biological Databases and Curation, and Nucleic Acids Research, among many others. (iscb.org)
Genome4
Databases in the area of nucleic acids include 3DIV for visualisation of data on genome 3D structure and RNArchitecture, a hierarchical classification of RNA families. (nih.gov)
We developed this relational database to provide researchers an integrated resource for analyzing papillomavirus genome sequences. (nih.gov)
The new NCBI Assembly database provides statistics, update history and links to sequences for eukaryotic genome assemblies including assemblies for previous genome builds. (nih.gov)
Assemblies are also linked through the Genome database main page or from a Genome record for a eukaryotic species as shown in Figure 1 . (nih.gov)
Protein4
Protein databases include the established SMART, ELM and MEROPS while GPCRdb and the newcomer STCRDab cover families of biomedical interest. (nih.gov)
The HLA-B gene has many possible variations, that result in the production of proteins that differ by changes in at least one protein building block (amino acid). (medlineplus.gov)
Our working knowledge of biological databases-such as the databases offered through the National Center for Biotechnology Information (NCBI), Universal Protein Resource (UniProt), Kyoto Encyclopedia of Genes and Genomes (KEGG), and Gene Ontology (GO) -can help you extend the scope of your dataset. (nih.gov)
NrichD database: sequence databases enriched with computationally designed protein-like sequences aid in remote homology detection. (ncbs.res.in)
Proteins3
Several projects to generate stable trajectory databases have been developed for proteins, but no equivalence exists in the nucleic acids world. (ub.es)
The Transporter Classification Database (or TCDB ) is an International Union of Biochemistry and Molecular Biology (IUBMB)-approved classification system for membrane transport proteins , including ion channels . (wikipedia.org)
Expression of genes occurs through transcription - the assembly of continuous, single stranded, messenger ribonucleic acid (mRNA) copies of exons, which are translated into proteins. (ddw-online.com)
Issue7
The entire Database Issue is freely available online on the Nucleic Acids Research website (https://academic.oup.com/nar). (nih.gov)
Read about NCBI resources in 2020 Nucleic Acids Research database issue (links) NCBI Insights, Feb 5, 2020. (cdc.gov)
Research5
The National Center for Biotechnology Information (NCBI), a division of the U.S. National Library of Medicine, provides access to scientific and biomedical databases, software tools for analyzing molecular data, and performs research in computational biology. (nih.gov)
Describes the NCBI databases and search engines in depth, and provides technical details about how the databases work or how they can be leveraged for bioinformatics research on a larger scale. (nih.gov)
We can help develop scientific databases necessary for research analysis. (nih.gov)
WikiPathways: a multifaceted pathway database bridging metabolomics to other omics research. (crossref.org)
Biological2
Individual crystal structure databases cater for users in specific chemical, molecular-biological, or related disciplines by covering super- or subsets of these categories. (wikipedia.org)
BIOBASE is a leading provider of manually-curated biological databases, software and services for the life sciences. (iscb.org)
Nucleotide2
The DNA Data Bank of Japan (DDBJ, http://www.ddbj.nig.ac.jp) provides a nucleotide sequence archive database and accompanying database tools for sequence submission, entry retrieval and annotation analysis. (nih.gov)
GRSDB2 and GRS_UTRdb: Databases of Quadruplex Forming G-rich Sequences in pre-mRNAs and mRNAs. (ramapo.edu)
Sequencing1
B efore discussing specific areas of drug discovery and development that we anticipate will be profoundly impacted by Generation II (or NextGen) sequencing, we first review current knowledge of nucleic acid variation, its functional correlates, and the current technical capabilities of Generation II sequencers. (ddw-online.com)
Relational database2
Newer versions are built on the relational database model and support the Crystallographic Information File (CIF) as a universal data exchange format. (wikipedia.org)
Newer versions of crystallographic databases are built on the relational database model, which enables efficient cross-referencing of tables. (wikipedia.org)
Molecular3
The NAR online Molecular Biology Database Collection has been updated, reviewing 138 entries, adding 88 new resources and eliminating 47 discontinued URLs, bringing the current total to 1737 databases. (nih.gov)
The Molecular Biology Database Collection" Web page [April 10, 2006: This link was removed because it is no longer valid. (nih.gov)
Initially we proposed data warehouse (DW) schemas which are able to integrate molecular descriptors from different databases and relate them with VS experimental data [ 6 ]. (hindawi.com)
Chemistry1
The ChEBI reference database and ontology for biologically relevant chemistry: enhancements for 2013. (crossref.org)
Resources1
However, they often lack the resources or skills to analyze data in the context of multi-dimensional databases associated with metagenomic analysis. (nih.gov)
Analysis4
Crystallographic databases differ in access and usage rights and offer varying degrees of search and analysis capacity. (wikipedia.org)
The database is based on the combination of two NoSQL engines, Cassandra for storing trajectories and MongoDB to store analysis results and simulation metadata. (ub.es)
The Ribosomal Database Project: improved alignments and new tools for rRNA analysis. (nih.gov)
The Ribosomal Database Project (RDP) provides researchers with quality-controlled bacterial and archaeal small subunit rRNA alignments and analysis tools. (nih.gov)
Biomedical1
Creating the next generation of human mtDNA control region sequence database for biomedical and forensic science / John Crews. (nih.gov)
Crystal structures of crystalline material are typically determined from X-ray or neutron single-crystal diffraction data and stored in crystal structure databases. (wikipedia.org)
They are routinely identified by comparing reflection intensities and lattice spacings from X-ray powder diffraction data with entries in powder-diffraction fingerprinting databases. (wikipedia.org)
Cross-referencing serves to derive additional data or enhance the search capacity of the database. (wikipedia.org)
Data exchange among crystallographic databases, structure visualization software, and structure refinement programs has been facilitated by the emergence of the Crystallographic Information File (CIF) format. (wikipedia.org)
Website2
CIFs may be accessible directly from the publisher's website, crystallographic databases, or both. (wikipedia.org)
These workshops provide hands-on experience exploring practical examples using tools and databases on the NCBI website. (nih.gov)
Researchers1
To assist HA researchers conducting genotyping analyses, we have developed a listing of F8 mutations including those listed in existing locus-specific databases as well as those identified in patient populations and reported in the literature. (cdc.gov)
Article1
In this article, we describe these new functions of the DDBJ databases and support tools. (nih.gov)
Structure4
A crystallographic database is a database specifically designed to store information about the structure of molecules and crystals. (wikipedia.org)
They are stored in crystal structure databases specializing in nanocrystals and can be identified by comparing zone axis subsets in lattice-fringe fingerprint plots with entries in a lattice-fringe fingerprinting database. (wikipedia.org)
As of 2008, more than 700,000 crystal structures had been published and stored in crystal structure databases. (wikipedia.org)
We elaborated protocols for two common conformer generation use cases and applied them to both programs: (i) high-throughput settings for processing large databases and (ii) high-quality settings for binding site exploration or lead structure refinement. (acs.org)
Assembly4
The database contains the placement of each scaffold in the assembly along with the name and sequence accession and version for each chromosome and scaffold. (nih.gov)
The database also organizes and provides assembly descriptive items such as assembly names and synonyms, as well as statistical reports including scaffold counts and weighted scaffold and contig length medians (N50). (nih.gov)
The Assembly Help documentation provides more detailed information on using the Assembly Database. (nih.gov)