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  • axonal growth
  • Title: Sip1 downstream Effector ninein controls neocortical axonal growth, ipsilateral branching, and microtubule growth and stability. (nih.gov)
  • nocodazole
  • Consequently, after depolymerization with nocodazole, microtubules did not regrow at the centrosome at later stages of development. (uni-muenchen.de)
  • We assayed microtubule regrowth following nocodazole washout in human fibroblasts and CHO-K1 cells adhered to fibronectin in either normal serum-free medium or the serum-free, growth-promoting medium, CCM1, which contains IGF1 and androgen, as well as other nutrients. (biologists.org)
  • cell
  • While the centrosome is necessary for cell cycle progression and neurogenesis, neuronal differentiation requires sophisticated architectural changes that may be incompatible with a large microtubule network emanating from a focal point. (uni-muenchen.de)
  • The results indicate that integrin-mediated adhesion is not sufficient to promote rapid microtubule regrowth in either cell type. (biologists.org)
  • The centrosome controls the number and distribution of microtubules--a major element of the cell cytoskeleton--and hence influences many impo. (worldcat.org)
  • May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2 (PubMed:16824950). (genecards.org)
  • We have shown that duplication of the centrosome, the microtubule organizing center of animal cells, is dependent on the cell cycle kinase cdk2, and on cell cycle-specific proteolysis. (stanford.edu)
  • In cell biology , the centrosome is an organelle that is the main place where cell microtubules are organized. (wikipedia.org)