• Rapid immunoprecipitation mass spectrometry of endogenous protein (RIME) is a method that allows the study of protein complexes, in particular chromatin and transcription factor complexes, in a rapid and robust manner by mass spectrometry (MS). The method can be used in parallel with chromatin immunoprecipitation-sequencing (ChIP-seq) experiments to provide information on both the cistrome and interactome for a given protein. (nature.com)
  • Dunham, W.H., Mullin, M. & Gingras, A.C. Affinity-purification coupled to mass spectrometry: basic principles and strategies. (nature.com)
  • Kocher, T. & Superti-Furga, G. Mass spectrometry-based functional proteomics: from molecular machines to protein networks. (nature.com)
  • Affinity purification-mass spectrometry and network analysis to understand protein-protein interactions. (nature.com)
  • Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. (nature.com)
  • Babu, M., Krogan, N.J., Awrey, D.E., Emili, A. & Greenblatt, J.F. Systematic characterization of the protein interaction network and protein complexes in Saccharomyces cerevisiae using tandem affinity purification and mass spectrometry. (nature.com)
  • Accelerator mass spectrometry (AMS) is a form of mass spectrometry that accelerates ions to extraordinarily high kinetic energies before mass analysis. (wikipedia.org)
  • The special strength of AMS among the different methods of mass spectrometry is its ability to separate a rare isotope from an abundant neighboring mass ("abundance sensitivity", e.g. 14C from 12C). (wikipedia.org)
  • An analytical method based on a desalting step and quantification with liquid chromatography coupled to mass spectrometry was therefore developed. (hal.science)
  • The headspace vapors are analyzed using GC-mass spectrometry (MS), which provides a detection sensitivity of between 1 and 5 nM (0.056 and 0.28 g/L) acrolein in urine. (cdc.gov)
  • We established an efficient approach, crosslinking of segmentally isotope-labeled RNA and tandem mass spectrometry (CLIR-MS/MS), to localize protein-RNA interactions simultaneously at amino acid and nucleotide resolution. (nih.gov)
  • Mass spectrometry is used to determine the molecular mass, the elemental composition, structure and sometimes amount of chemical species in a sample by ionizing the analyte molecules and observing their behavior in electric and magnetic fields. (newworldencyclopedia.org)
  • Examples of this include ICP-MS (Inductively-Coupled Plasma - Mass Spectrometry), where volatilization of a sample occurs in the first step, and measuring of the concentration occurs in the second. (newworldencyclopedia.org)
  • Similar considerations as for AMS evolve for the young but growing technique of highly selective laser based mass spectrometry, which utilizes the isobaric and isotopic selective properties of resonant step-wise optical ionization processes. (psi.ch)
  • Here we used an affinity-purification mass spectrometry-based (AP-MS) approach to identify novel and particularly intracellular sGAG-interacting proteins in human bone marrow stromal cells (hBMSC). (degruyter.com)
  • A new multi-isotope plutonium standard for isotopic ratio measurements with Accelerator Mass Spectrometry (AMS) was created by gravimetric mixing of different single-isotope standards provided by IRMM (Pu-239, Pu-240, Pu-242, Pu-244). (uni-koeln.de)
  • Additionally, the material was characterized using a Neptune MC-ICPMS (multi-collector inductively coupled plasma mass spectrometry) at the joint Cologne-Bonn isotope facility. (uni-koeln.de)
  • Ultraperformance liquid chromatography/quadrupole time-of-flight mass spectrometry revealed 10 metabolites. (aspetjournals.org)
  • Department of Mass Spectrometry is involved in environmental and nuclear medicine studies. (edu.pl)
  • The latest update of MALDI-TOF mass spectrometry database includes M. conceptionense , but we did not find this species among the top matches. (cdc.gov)
  • Therefore, using a combination of 16S rRNA/rpoB gene sequencing and MALDI-TOF mass spectrometry, we identified the isolate as M. senegalense . (cdc.gov)
  • Gel-based protein separation was performed on saliva, followed by identification of proteins using Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS). Totally, 326 proteins were identified in the salivary samples, among which 101 were found to be specific for ruptured ectopic pregnancy (EPR). (bvsalud.org)
  • We utilize accelerator mass spectrometry ( 14 C-AMS) to study the impact of mid-century nuclear weapons tests. (lu.se)
  • All analyses are based on Accelerator Mass Spectrometry (AMS). (lu.se)
  • [ 11-13 ] By contrast, we discovered, using laser capture microdissection and mass spectrometry, that keratin 17 (K17) could predict the overall survival of patients with cervical squamous cell carcinoma more accurately than grade, stage, or any other clinicopathologic features. (medscape.com)
  • Thanks to the high energy of the ions, these can be separated by methods borrowed from nuclear physics, like degrader foils and gas-filled magnets. (wikipedia.org)
  • Exotic radionuclides such as for instance 44 Ti, 60 Fe, 26 Al, 10 Be and many others are of great interest in several research domains like astrophysics, nuclear medicine, geophysics, fundamental nuclear physics or radioactive beam facilities. (psi.ch)
  • Providing rare radionuclide samples in sufficient amount for such facilities would open new possibilities for studies in the field of fundamental nuclear physics. (psi.ch)
  • Positron emission tomography (PET) is an important development in this field of the application of nuclear physics to medicine. (psi.ch)
  • A key in this endeavor is the understanding of the underlying nuclear physics of unstable nuclei that span the entire range from the proton drip line to the neutron drip line. (cern.ch)
  • Imagine helping with nuclear physics experiments in the Edwards Accelerator Laboratory. (ohio.edu)
  • The 10th Latin American Symposium on Nuclear Physics and Applications will be held on December 1-6, 2013 in Montevideo, Uruguay. (sissa.it)
  • During year 2017 and 2018 researchers from Lund University (Medical Radiation Physics, Malmö, and Nuclear Physics, Lund) performed extensive measurements of the radiation environment around ESS prior to start of operation. (lu.se)
  • The Nuclear medicine unit of the Medical radiation physics research group, Malmö, Lund university has a long tradition of performing biokinetic studies and producing dosimetric models. (lu.se)
  • ELSE NUCLEAR, thanks to collaborations with universities and international research centres, achieved important results in developing highly specialized spectrometry systems for gamma and neutron radiation. (elsenuclear.com)
  • Up to date, ELSE NUCLEAR supplied gamma and neutron spectrometry systems to research facilities, steel foundries, nuclear power plants, and particle accelerator facilities. (elsenuclear.com)
  • HERMES systems are portable, easily deployable units designed to perform field measurements of gamma radiation or gamma spectrometry analysis, for applications such as radiation monitoring, geology research, laboratory analysis, environmental survey, etc. (elsenuclear.com)
  • Inline gamma-spectrometry of fission product elements after rapid high-pressure ion chromatographic separation. (ornl.gov)
  • To address the limitations of existing methodologies and in accordance with the directives of the Nuclear Safety Authority (ASN), the proposed doctoral research aims to develop an innovative and efficient non-destructive radiological characterization methodology using machine learning algorithms (artificial intelligence) for automated analysis of in-situ gamma spectrometry measurements with a highly resolved Germanium detector. (cea.fr)
  • The doctoral candidate will work within a team with extensive experience in the development and in situ implementation of non-destructive radiological characterization techniques (alpha and gamma imaging techniques, alpha, beta, and gamma spectrometry techniques). (cea.fr)
  • To estimate the possibility to return to an affected area, the spatial distribution of deposition density of the radionuclides within the area has to be evaluated using mobile gamma spectrometry. (lu.se)
  • In radiological emergencies involving lost radioactive sources, mobile gamma spectrometry equipment is used to survey the area where the source is. (lu.se)
  • Thus, the aim of this thesis was to investigate the feasibility of a Bayesian‑based approach for mobile gamma spectrometry applications in radiological emergencies. (lu.se)
  • Despite the shown potential of Bayesian methods in mobile gamma spectrometry within this thesis, further investigations are needed to validate the findings discussed. (lu.se)
  • Nuclear magnetic resonance imaging showed inflamed fistulous tracts. (cdc.gov)
  • Nuclear magnetic resonance imaging showed bone impairment and new fistulous tracts. (cdc.gov)
  • The single sphere neutron spectrometer (SP2) is a unique tool that allows performing active neutron spectrometry measurements by employing a single device instead of the usual multi-sphere Bonner spectrometers. (elsenuclear.com)
  • The devices designed so far provide fast and reliable spectrometry measurements in a wide range of conditions. (elsenuclear.com)
  • Our joint efforts focus on isotopes 3 H and 14 C near nuclear power plants. (lu.se)
  • This is a large nuclear particle accelerator based on the principle of a Tandem van de Graaff Accelerator operating at 0.2 to many million volts with two stages operating in tandem to accelerate the particles. (wikipedia.org)
  • These sources include nuclear power plants, research laboratories, and accelerator facilities. (lu.se)
  • The Qproteome Nuclear Protein Kit is designed for specific enrichment of nuclear proteins from cultured mammalian cells. (qiagen.com)
  • A high-salt buffer allows dissociation of nuclear binding proteins (such as transcription factors) and their removal by diffusion from the nuclei. (qiagen.com)
  • Understanding the radiological inventory of a nuclear installation is paramount to ensure the control of safety and criticality risks throughout the facility's lifespan, as well as to manage the radiological impact on both human health and the environment. (cea.fr)
  • First Responders should use a NIOSH-certified Chemical, Biological, Radiological, Nuclear (CBRN) Self Contained Breathing Apparatus (SCBA) with a Level A protective suit. (cdc.gov)
  • Flame emission and atomic absorption spectrometry (FES and AAS). (chipsbooks.com)
  • The characterization methodology developed as a result of this project holds significant potential for industrial applications, particularly in the field of nuclear facility decontamination and dismantling. (cea.fr)
  • The Qproteome Nuclear Protein Kit is intended for molecular biology applications. (qiagen.com)
  • Indiana University researchers have reported the first definitive evidence for a new molecular structure with potential applications to the safe storage of nuclear waste and reduction of chemicals that contaminate water and trigger large fish kills. (labmanager.com)
  • Nuclear medicine (NM) / molecular imaging (MI) is a medical speciality that uses radioactive tracers of nanogram levels, in order to diagnose, confirm or exclude various pathologies and diseases in the body or for staging of malignancies and follow-up after therapy. (lu.se)
  • Radioactive beam facilities are a tool for studying basic nuclear reactions. (psi.ch)
  • RBS is performed at Triangle Universities Nuclear Laboratory (TUNL) to better understand the targets that are used in experiments. (aps.org)
  • [ 14 ] Subsequent work in our laboratory demonstrated that K17 serves as a nuclear shuttle of p27KIP1, resulting in sustained cell cycle progression. (medscape.com)
  • The desired profile is a candidate with an engineering school or Master's degree (M2) background and strong knowledge in nuclear instrumentation and measurement, particularly in the physical phenomena related to the interactions of ionizing radiation with matter. (cea.fr)
  • New approaches in systemic radioisotope therapy require radionuclides that have different nuclear properties in comparison to those used for diagnostics. (psi.ch)
  • The analytical method was successfully applied to real nuclear effluents, with a limit of quantification of 2.6 × 10−5 mol L−1. (hal.science)
  • The overall conclusion of the thesis is that Bayesian methods can be successfully applied to mobile spectrometry data. (lu.se)
  • Thanks to the high energy of the ions, these detectors can provide additional identification of background isobars by nuclear-charge determination. (wikipedia.org)
  • The need for speed - Burnup determination of spent nuclear fuel. (ornl.gov)
  • ISO 16795:2004 covers the determination of Gd 2 O 3 in sintered fuel pellets, by X-ray fluorescence spectrometry using the Gd L-alpha line. (iso.org)
  • Rutherford backscattering spectrometry (RBS) is a technique used to characterize solids via surface- layer analysis. (aps.org)
  • Marie Sydoff, "Quantification methods for clinical studies in nuclear medicine - Applications in AMS, PET/CT and SPECT/CT", 2013, (PhD Thesis). (lu.se)
  • During the dismantling of a nuclear facility, decontamination operations are necessary to reclassify areas from nuclear waste zones to conventional waste zones. (cea.fr)
  • Is the Subject Area "Nuclear decontamination" applicable to this article? (plos.org)
  • Analytical Report for Nuclear Regulatory Commission High Burnup Fuel Specimens. (ornl.gov)
  • Nuclear Analytical and Chemical Isotopics Laboratories Sample Analytical Plan for the Sister Rod Spent Nuclear Fuel Specimens. (ornl.gov)
  • Due to their ion-extraction properties, the molecules could potentially be used to remove sulfate ions from the process used to transform nuclear waste into storable solids-a method called vitrification, which is harmed by these ions-as well as to extract harmful phosphate ions from the environment. (labmanager.com)
  • Nuclear technology and the use of radiation sources have been extensively adopted in the modern world. (lu.se)
  • Martin Andersson, "Radiation dose to patients in diagnostic nuclear medicine. (lu.se)
  • Sigrid Leide Svegborn, "Radiation exposure of the patient in diagnostic nuclear medicine. (lu.se)
  • The measurement of gluconate is required in the framework of nuclear waste management. (hal.science)
  • Also, any isobaric background is drastically suppressed by means of nuclear measurement techniques which are involved. (psi.ch)
  • The approach was tested on polypyrimidine tract binding protein 1 and U1 small nuclear RNP. (nih.gov)
  • The Qproteome Nuclear Protein Kit delivers a nucleic acid binding protein fraction suitable for a wide range of activity assays. (qiagen.com)
  • In healthy individuals, cryopyrin and apoptosis-associated speck-like protein (ASC) interact via the oligomerization of ASC to induce both apoptosis and activate nuclear factor (NF)-kappa B. (medscape.com)
  • Few of the most known are accidents in Chernobyl and Fukushima nuclear power plants. (lu.se)
  • The ultimate goal is to establish real-time three-dimensional maps of contaminant distribution within contaminated civil engineering structures of nuclear facilities. (cea.fr)
  • Traditionally, the purpose of these symposia is the dissemination of major theoretical and experimental advances in nuclear science, with emphasis on research topics carried out by Latin American groups or in collaborations involving institutions from Latin America. (sissa.it)