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  • induce
  • The seminar will study the competition between transcription factors by TF competition ChIP and investigate the finding that a cell fate determination factor must stay longer to induce reprogramming than it was previously considered. (edu.pk)
  • Yet, it is becoming increasingly clear that the reprogramming process, including retroviral transduction with potent oncogenes like c-Myc and long-term cultivation, may induce genetic instability. (semanticscholar.org)
  • Gurdon
  • Professor Sir John Gurdon is an English developmental biologist, best known for his pioneering research in nuclear transplantation and cloning. (cam.ac.uk)
  • Professor Sir Gurdon went to Christ Church, Oxford to study classics, before switching to zoology and completing a DPhil degree studying nuclear transplantation in a frog species of the genus Xenopus. (cam.ac.uk)
  • Cellular
  • Here we describe a novel property of the Epstein-Barr virus (EBV) nuclear antigen-1 (EBNA1) that may underlie the capacity of the virus to promote a global remodeling of chromatin architecture and cellular transcription. (ovid.com)
  • tissue
  • The idea of taking a mature cell and removing its identity (nuclear reprogramming) so that it can then become any kind of cell, holds great promise for repairing damaged tissue or replacing bone marrow after chemotherapy. (blogspot.ca)
  • research
  • A group from the Spanish National Cancer Research Centre (CNIO), headed by researcher Ralph P. Schneider, from the Telomeres and Telomerase Group led by MarĂ­a A. Blasco, publishes this week an article in Nature Communications on the discovery of a new gene called TRF1 that is essential for nuclear reprogramming. (cnio.es)