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Cell Line COS Cells Cell Line, Tumor Cells, Cultured Cell Membrane HeLa Cells 3T3 Cells NIH 3T3 Cells Fibroblasts Melanocytes HEK293 Cells Cytoskeleton Cell Nucleus Tumor Cells, Cultured Cell Line, Transformed

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Escherichia coli Saccharomyces cerevisiae Mice, Transgenic Cercopithecus aethiops Mice, Inbred C57BL Cricetinae Drosophila melanogaster Drosophila Mice, Mutant Strains Mice, Knockout Caenorhabditis elegans

Diseases19

Leukemia, Myelomonocytic, Juvenile Melanoma Nevus, Pigmented Skin Neoplasms Leukemia, Myelomonocytic, Chronic Cell Transformation, Neoplastic Neurocutaneous Syndromes Syndrome Genetic Predisposition to Disease Noonan Syndrome Melanosis Leukemia, Myeloid, Acute Retinitis Pigmentosa Genetic Diseases, X-Linked Hyperpigmentation Disease Models, Animal Colorectal Neoplasms Lung Neoplasms Abnormalities, Multiple

Chemicals and Drugs93

ras Proteins Proto-Oncogene Proteins B-raf ras GTPase-Activating Proteins Proto-Oncogene Proteins p21(ras)p120 GTPase Activating Protein GTP Phosphohydrolases GTPase-Activating Proteins Neurofibromin 1 Proteins Membrane Proteins Oncogene Protein p21(ras)Guanosine Triphosphate rho GTP-Binding Proteins Monomeric GTP-Binding Proteins rab GTP-Binding Proteins GTP-Binding Proteins Guanine Nucleotide Exchange Factors Guanosine Diphosphate Codon rac1 GTP-Binding Protein Proto-Oncogene Proteins Proto-Oncogene Proteins c-raf Codon, Nonsense DNA Primers rac GTP-Binding Proteins DNA-Binding Proteins Mutant Proteins Recombinant Fusion Proteins rhoA GTP-Binding Protein Transcription Factors Carrier Proteins Dynamins raf Kinases Saccharomyces cerevisiae Proteins Recombinant Proteins ras Guanine Nucleotide Exchange Factors rap GTP-Binding Proteins Bacterial Proteins Nuclear Proteins Fungal Proteins Protein-Serine-Threonine Kinases DNA, Neoplasm Phosphatidylinositol 3-Kinases ran GTP-Binding Protein DNA ral GTP-Binding Proteins rap1 GTP-Binding Proteins GTP Phosphohydrolase-Linked Elongation Factors RNA, Messenger Drosophila Proteins Actins Dynamin I fms-Like Tyrosine Kinase 3 Eye Proteins DNA, Mitochondrial ADP-Ribosylation Factors Tumor Suppressor Protein p53 Mitogen-Activated Protein Kinase Kinases Cell Cycle Proteins DNA, Complementary Phosphoric Monoester Hydrolases Cytoskeletal Proteins Protein Kinase Inhibitors Adaptor Proteins, Signal Transducing Repressor Proteins MAP Kinase Kinase 1 Escherichia coli Proteins Neoplasm Proteins rab1 GTP-Binding Proteins ral Guanine Nucleotide Exchange Factor Intracellular Signaling Peptides and Proteins Receptor, Epidermal Growth Factor Vesicular Transport Proteins Nerve Tissue Proteins ras-GRF1 Dynamin II Guanine Nucleotide Dissociation Inhibitors Extracellular Signal-Regulated MAP Kinases RGS Proteins Mitogen-Activated Protein Kinases Mutagens Tumor Suppressor Proteins Phosphoproteins cdc42 GTP-Binding Protein, Saccharomyces cerevisiae Trans-Activators Protein-Tyrosine Kinases Ethylnitrosourea RNA Splice Sites Enzyme Inhibitors Caenorhabditis elegans Proteins Aspartic Acid Adenosine Triphosphatases Proto-Oncogene Proteins c-kit

Analytical, Diagnostic and Therapeutic Techniques and Equipment29

DNA Mutational Analysis Prognosis Pedigree Amino Acid Substitution Polymerase Chain Reaction Mutagenesis, Site-Directed Sequence Analysis, DNA Models, Molecular Transfection Cloning, Molecular Sequence Alignment Genetic Testing Chromosome Mapping Genetic Complementation Test Models, Biological Models, Genetic Blotting, Western Mutagenesis, Insertional Heterozygote Detection Genetic Association Studies Two-Hybrid System Techniques Reverse Transcriptase Polymerase Chain Reaction Crosses, Genetic Restriction Mapping Disease Models, Animal Microscopy, Fluorescence Immunohistochemistry Crystallography, X-Ray Immunoblotting

Phenomena and Processes87

Genes, ras Mutation Point Mutation Mutation, Missense Amino Acid Sequence Signal Transduction Frameshift Mutation Gene Frequency Germ-Line Mutation Mutation Rate Base Sequence Amino Acid Substitution Exons Heterozygote Alleles Protein Structure, Tertiary Polymorphism, Single-Stranded Conformational Protein Binding Mutagenesis Phenotype Sequence Homology, Amino Acid Genotype Genes, Dominant Codon Homozygote Binding Sites Codon, Nonsense Transfection Sequence Deletion Suppression, Genetic Genes, Recessive Enzyme Activation Gene Deletion Phosphorylation Kinetics Plasmids Protein Transport Genes, p53 Transcription, Genetic Protein Conformation Founder Effect Promoter Regions, Genetic Structure-Activity Relationship Genetic Linkage Genes, Lethal Genetic Predisposition to Disease MAP Kinase Signaling System Gene Expression Regulation Hydrolysis Consanguinity Oncogenes Conserved Sequence Genes, Fungal Genes, Suppressor Mutagenesis, Insertional Gene Dosage Gene Expression Regulation, Neoplastic Polymorphism, Genetic Temperature Gene Expression Exome Genes, BRCA1 Protein Structure, Secondary Genetic Variation Introns Amino Acid Motifs Genes, Bacterial Lipoylation Cell Division Cell Proliferation Mosaicism Recombination, Genetic Genes Apoptosis Microsatellite Repeats Drug Resistance, Viral Evolution, Molecular Time Factors Polymorphism, Restriction Fragment Length Penetrance Ultraviolet Rays RNA Splicing INDEL Mutation Genes, BRCA2 Endocytosis RNA Splice Sites Selection, Genetic

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Pathology, Molecular Immunohistochemistry

Information Science3

Molecular Sequence Data Amino Acid Sequence Base Sequence

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Health Care5

Genetic Testing Temperature Family Health Age of Onset Ultraviolet Rays

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ras Proteins Proto-Oncogene Proteins B-raf Genes, ras ras GTPase-Activating Proteins Proto-Oncogene Proteins p21(ras)p120 GTPase Activating Protein Leukemia, Myelomonocytic, Juvenile GTP Phosphohydrolases Mutation GTPase-Activating Proteins Melanoma Nevus, Pigmented Skin Neoplasms Pathology, Molecular Neurofibromin 1 DNA Mutational Analysis Point Mutation Mutation, Missense Proteins Molecular Sequence Data Amino Acid Sequence Signal Transduction Frameshift Mutation Membrane Proteins Oncogene Protein p21(ras)Gene Frequency Germ-Line Mutation Mutation Rate Prognosis Pedigree Base Sequence Amino Acid Substitution Guanosine Triphosphate Exons Polymerase Chain Reaction rho GTP-Binding Proteins Heterozygote Alleles Monomeric GTP-Binding Proteins Mutagenesis, Site-Directed Protein Structure, Tertiary Polymorphism, Single-Stranded Conformational rab GTP-Binding Proteins GTP-Binding Proteins Protein Binding Cell Line Mutagenesis Sequence Analysis, DNA Guanine Nucleotide Exchange Factors Phenotype Sequence Homology, Amino Acid Genotype Genes, Dominant Guanosine Diphosphate Codon Homozygote Binding Sites rac1 GTP-Binding Protein Proto-Oncogene Proteins Escherichia coli Models, Molecular Proto-Oncogene Proteins c-raf Codon, Nonsense Leukemia, Myelomonocytic, Chronic DNA Primers Saccharomyces cerevisiae Transfection rac GTP-Binding Proteins Sequence Deletion Suppression, Genetic Genes, Recessive Cell Transformation, Neoplastic Cloning, Molecular DNA-Binding Proteins Mutant Proteins Recombinant Fusion Proteins Enzyme Activation Sequence Alignment rhoA GTP-Binding Protein Gene Deletion Genetic Testing Transcription Factors Phosphorylation Carrier Proteins Dynamins raf Kinases Saccharomyces cerevisiae Proteins Neurocutaneous Syndromes Recombinant Proteins COS Cells Chromosome Mapping Kinetics Genetic Complementation Test ras Guanine Nucleotide Exchange Factors rap GTP-Binding Proteins Plasmids Protein Transport Cell Line, Tumor Bacterial Proteins Nuclear Proteins

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