Tumor Suppressor Protein p53Genes, Tumor SuppressorTumor Suppressor ProteinsCell Line, TumorProto-Oncogene Proteins c-mdm2ApoptosisGene Expression Regulation, NeoplasticVon Hippel-Lindau Tumor Suppressor ProteinTumor Cells, CulturedCyclin-Dependent Kinase Inhibitor p21TransfectionPromoter Regions, GeneticProtein BindingNuclear ProteinsTumor Suppressor Protein p14ARFMutationLoss of HeterozygosityDNA MethylationGenes, p53Molecular Sequence DataCell ProliferationDown-RegulationCell LineTranscription FactorsGene SilencingCyclinsBase SequenceDNA-Binding ProteinsRetinoblastoma ProteinRNA, MessengerProto-Oncogene ProteinsDNA DamageTranscriptional ActivationCell CycleSignal TransductionAmino Acid SequenceGene DeletionNeoplasm ProteinsMice, NudeCell Cycle ProteinsTranscription, GeneticUbiquitin-Protein LigasesPhosphorylationBinding SitesReverse Transcriptase Polymerase Chain ReactionBlotting, WesternCell DivisionOncogene Proteins, ViralProtein Structure, TertiaryAdenovirus E1B ProteinsNeoplasmsHeLa CellsFibroblastsUbiquitinsUltraviolet RaysNeurofibromin 2DNAGene Expression RegulationCell Growth ProcessesAdenomatous Polyposis Coli ProteinAntigens, Polyomavirus Transformingbcl-2-Associated X ProteinChromosome MappingCell Transformation, NeoplasticCells, CulturedPrecipitin TestsRecombinant Fusion ProteinsProteasome Endopeptidase ComplexCyclin-Dependent Kinase Inhibitor p16Consensus SequenceLung NeoplasmsTumor Markers, BiologicalCell NucleusSpodopteraGenes, SuppressorTrans-ActivatorsPTEN PhosphohydrolaseDNA PrimersRNA, Small InterferingProteinsRecombinant ProteinsProto-Oncogene Proteins c-bcl-2AcetylationPapillomaviridaeMice, KnockoutE2F Transcription FactorsLigasesCell SurvivalCarrier ProteinsRepressor ProteinsProtein-Serine-Threonine KinasesModels, BiologicalSerineRetinoblastoma-Like Protein p107E2F1 Transcription FactorImmunohistochemistryRetinoblastoma-Like Protein p130Transcription Factor DP1Breast NeoplasmsRNA Interference