Novel coronavirus sars. Medical search. Frequent questions

Today, in a follow up to a SARS-like virus recently treated in the UK, the World Health Organization reports that no new cases due to infection with this novel coronavirus have been accounted for. (medicalnewstoday.com)
National Health Authorities can contact the laboratories that are performing the tests for the novel coronavirus infection of patients under examination. (medicalnewstoday.com)
Application of this assay will aid in diagnosing SARS-CoV infection. (nih.gov)
From the initial infection to the widespread impact on daily life, Understanding Coronaviruses examines the intricacies of SARS -CoV-2 and COVID -19 and how they compare to previous viruses and pandemics. (lernerbooks.com)
Epidemiology and clinical characteristics of human coronaviruses OC43, 229E, NL63, and HKU1: a study of hospitalized children with acute respiratory tract infection in Guangzhou, China. (eurosurveillance.org)
However, the effects of anti-seasonal CoV immunity on SARS-CoV-2 infection susceptibility and COVID-19 mRNA vaccinations are unclear. (news-medical.net)
With at least six previous exposures to various types of coronaviruses, researchers are exploring if antibodies created during earlier infection with coronaviruses can help to fight off SARS-CoV-2 infection. (scienceboard.net)
Effective prophylaxis and antiviral therapies are urgently needed in the event of reemergence of the highly contagious and often fatal severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) infection. (nih.gov)
Among vaccinated individuals without prior COVID-19 infection, SARS-COV-2 anti-spike IgG demonstrated a weak positive relationship between both HCoV-229E (r = 0.11) and HCoV-NL63 (r = 0.12). (frontiersin.org)
Previous studies have also shown that COVID-19 infections also result in significant protection against subsequent SARS-CoV-2 re-infection ( 3 - 5 ). (frontiersin.org)
Given the similarities between SARS-CoV-2 and HCoV's, and that exposure to HCoV's in the general population is common (at least prior to nonpharmaceutical interventions implemented during the COVID-19 pandemic), investigations into the potential correlation of HCoV's and SARS-COV-2 antibodies (through vaccination or previous COVID-19 infection) may provide further insight into their contribution to SARS-COV-2 immunity ( 1 , 9 - 11 ). (frontiersin.org)
Middle East respiratory syndrome is a coronavirus infection that causes severe flu-like symptoms. (msdmanuals.com)
Along with bats, the authors note that pangolins, as well as certain species of cat, civet, and weasels found in this region are readily susceptible to SARS-CoV-2 infection, and might represent intermediary hosts for transmission to humans. (sflorg.com)
Species above the threshold are vulnerable to letting the coronavirus enter the cell while those below have significantly lower or no risk for infection. (scitechdaily.com)
Five species - humans, cats, ferrets, civets, and dogs - have had documented cases of infection by SARS-CoV-2. (scitechdaily.com)
Considering both binding affinity and the codon adaptation index, the researchers conclude that humans, followed by ferrets, cats, civets, and dogs are the most susceptible animals to infection by coronavirus. (scitechdaily.com)
Case reports and rare case series have demonstrated variable placental pathology in the setting of maternal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. (allenpress.com)
A retrospective study of 7 placentas from mothers with active SARS-CoV-2 infection and placental infection as demonstrated by RNA in situ hybridization was conducted. (allenpress.com)
A total of 5 of the 8 neonates (including the stillbirth) tested negative for SARS-CoV-2, and all were negative for neonatal infection. (allenpress.com)
All placentas were positive for SARS-CoV-2 infection by RNA in situ hybridization and demonstrated variable degrees of histiocytic intervillositis, perivillous fibrin deposition, and trophoblast necrosis. (allenpress.com)
7 Despite the critical role that the placenta plays in mediating these consequences, few publications have described the histopathologic features of placental SARS-CoV-2 infection. (allenpress.com)
13 - 17 These early studies were largely retrospective reviews of placentas from all SARS-CoV-2-infected mothers, irrespective of active placental infection (ie, no confirmation of SARS-CoV-2 infection in the placental parenchyma). (allenpress.com)
A new claim is that the potentially deadly infection is a "man-made" combination of parts of the HIV-1 virus and the SARS virus. (aap.com.au)
Title : Inhibition of SARS Coronavirus Infection In Vitro with Clinically Approved Antiviral Drugs Personal Author(s) : Tan, Emily L.C.;Ooi, Eng Eong;Lin, Chin-Yo;Tan, Hwee Cheng;Ling, Ai Ee;Lim, Bing;Stanton, Lawrence W. (cdc.gov)
Currently, no effective drug exists to treat SARS-CoV infection. (cdc.gov)
Once a person has been infected by a coronavirus, the infection can spread to a healthy person (person-to-person transmission). (medlineplus.gov)
At this time, there is no specific treatment for coronavirus infection except for SARS-CoV-2. (medlineplus.gov)
For a coronavirus infection not due to SARS-CoV-2, medicines are given only to ease your symptoms. (medlineplus.gov)
Self-reported vaccination status and coronavirus disease 2019 (COVID-19) infection were recorded. (kcl.ac.uk)
Results: Of the 960 women, 196 (20.4%) were SARS-CoV-2 seropositive from previous infection. (kcl.ac.uk)
Conclusions: This cross-sectional study demonstrates high rates of asymptomatic SARS-CoV-2 infection with women of black ethnic backgrounds having higher infection risk and lower vaccine uptake. (kcl.ac.uk)
Epidemiology of Novel Coronavirus SARS-CoV-2 & Infection Prevention: How Is the Virus Transmitted? (vumedi.com)
SARS-CoV-2 uncertainty exists regarding whether its emergence into human populations appears to be a zoonotic infection or related to release from a laboratory studying the virus. (hopkinsguides.com)
The coronavirus disease 2019 (COVID-19) is a contagious respiratory tract infection caused by the betacoronavirus SARS-CoV-2. (academic-accelerator.com)
Severe acute respiratory syndrome (SARS) is a serious, potentially life-threatening viral infection caused by a previously unrecognized virus from the Coronaviridae family, the SARS-associated coronavirus (SARS-CoV). (medscape.com)
World map of severe acute respiratory syndrome (SARS) distribution from the 2002-2003 outbreak infection. (medscape.com)
An infected medical doc- spread of SARS infection. (who.int)
SARS infection out of China on 21 Febru- their close contacts and then the disease ary 2003 to Hong Kong. (who.int)

It also reported zero false-positives in 41 samples taken from healthy people before the pandemic started as well as 18 samples taken from individuals infected with four other widely circulating coronaviruses. (sciencedaily.com)
While many scientists believed influenza would cause the next great pandemic, no one was prepared for the new strain of coronavirus that appeared in 2019. (lernerbooks.com)
In the midst of the growing global coronavirus disease (COVID-19) pandemic, it's time we all made the connection between eating animals and major disease outbreaks around the world. (peta.org.uk)
The new coronavirus pandemic is thought to have originated at a "wet market" in the Chinese city of Wuhan in late 2019. (peta.org.uk)
The SARS pandemic started in China and resulted in an outbreak of deadly pneumonia that killed 774 people. (peta.org.uk)
The discovery described in the journal Nature Communications , along with the recent detection of the closest ancestors of SARS-CoV-2 known to date in cave-dwelling bats in Laos, indicates that SARS-CoV-2-related viruses that cause COVID-19 have a much wider geographic distribution than previously reported and further supports the hypothesis that the pandemic originated via spillover of a bat-borne virus. (sflorg.com)
Understanding SARS-CoV-2 infectivity across different species can better inform public health measures, helping reduce human contact with other susceptible animals and avoiding the potential prolongation of the COVID-19 pandemic. (scitechdaily.com)
The authors of the study say that the findings are further evidence that the transnational nature of the wildlife trade can facilitate coronavirus and other viral transmission and amplification along the trade chain, providing further evidence that pandemic and epidemic prevention must also be focused on pathogen spillover from wildlife. (wcs.org)
Simple Summary Nucleocapsid protein is one of the essential proteins for viral replication including the coronavirus SARS-CoV-2, which causes coronavirus disease 2019 (COVID-19) pneumonia leading to the ongoing pandemic. (academic-accelerator.com)
The COVID-19 pandemic caused by the coronavirus SARS-CoV-2 has become a serious challenge for medicine and science. (academic-accelerator.com)
Background: Coronavirus disease 2019 (COVID-19) has emerged as a pandemic for more than 2 years. (lu.se)

On January 2020, the discovery of a new coronavirus was announced (SARS-CoV-2). (pasteur.fr)
Surveillance microbiologique à l'AP-HM Point en semaine 7 (du 10 au 16 Février 2020). (eurosurveillance.org)
Reference: "Engineering human ACE2 to optimize binding to the spike protein of SARS coronavirus 2" by Kui K. Chan, Danielle Dorosky, Preeti Sharma, Shawn A. Abbasi, John M. Dye, David M. Kranz, Andrew S. Herbert and Erik Procko, 4 August 2020, Science . (scitechdaily.com)
In 2020, viruses of the SARS-CoV-2 sublineage, one exhibiting strong sequence similarity to SARS-CoV-2 in the receptor biding domain, were detected in distinct groups of pangolins seized during anti-smuggling operations in southeast China. (sflorg.com)
According to the WHO, since June 2020, 214 human cases of COVID-19 have been identified in Denmark with SARS-CoV-2 variants associated with farmed minks, including 12 cases with a unique variant, reported on November 5. (scitechdaily.com)
In addition to testing pangolins for SARS-CoV-2 related coronaviruses, the authors reviewed media reports of pangolin trafficking cases involving Viet Nam between 2016 and 2020. (wcs.org)
2020 clinical practice guidelines from the SIAARTI Airway Research Group and the European Airway Management Society on coronavirus disease 2019 (COVID-19)-related airway management. (medscape.com)
2020 interim clinical guidance by the Belgium Task Force for supportive care and antiviral/immunologic therapy for adults with suspected or confirmed coronavirus disease 2019 (COVID-19). (medscape.com)
2020 clinical practice guidelines from the Centers for Disease Control and Prevention on the collection, handling, and testing of specimens for the diagnosis of coronavirus disease 2019 (COVID-19). (medscape.com)
In March 2020, Hologic received Emergency Use Authorization for its first COVID-19 test, the Panther Fusion® SARS-CoV-2 assay. (hologic.com)

On April 14, 2003, the Centers for Disease Control and Prevention (CDC) announced the completion of the full-length genetic sequencing of the genome of the SARS-associated coronavirus (SARS-CoV). (cdc.gov)
This fact, together with the reappearance of the SARS-associated coronavirus (SARS-CoV) in China in late 2003, makes it clear that rapid and reliable diagnostic tools are essential for accurate disease reporting and subsequent disease management. (cdc.gov)
Here we examine the disease potential of a SARS-like virus, SHC014-CoV, which is currently circulating in Chinese horseshoe bat populations 1 . (nature.com)
This coronavirus is the agent responsible for the new infectious respiratory disease called Covid-19. (pasteur.fr)
Coronavirus disease 2019 (COVID-19) Situation Report - 36. (eurosurveillance.org)
Middle East respiratory syndrome (MERS) is another disease caused by a coronavirus. (peta.org.uk)
Severe acute respiratory syndrome (SARS) is a disease caused by a coronavirus that originated in wild animals - bats and civet cats - and was transmitted to humans. (peta.org.uk)
They also investigated the impact of pre-existing immune levels against seasonal CoV S on the immune protection conferred by messenger ribonucleic acid (mRNA) coronavirus disease 2019 (COVID-19) vaccinations. (news-medical.net)
More recently, MERS-CoV and SARS-CoV have emerged and caused severe disease in humans. (scienceboard.net)
Our findings highlight sites at which the SARS-CoV-2 response appears to be shaped by previous coronavirus exposures, and which have potential to raise broadly-neutralizing antibodies," said senior author, John Altin, PhD, assistant professor in TGen's infectious disease branch. (scienceboard.net)
This research could be a crucial step in helping scientists develop approaches to predict, by genome analysis alone, the severity of future coronavirus disease outbreaks and detect animal coronaviruses that have the potential to infect humans. (nih.gov)
In this work, we set out to identify genomic features unique to those coronaviruses that cause severe disease in humans," said Dr. Eugene Koonin, an NIH Distinguished Investigator in the intramural research program of NLM's National Center for Biotechnology Information, and the lead author of the study. (nih.gov)
These features are found in all three high-fatality coronaviruses and their closest relatives that infect animals, such as bats, but not in four other human coronaviruses that cause non-fatal disease. (nih.gov)
Finding these features in animal coronavirus isolates could predict the jump to humans and the severity of disease caused by such isolates. (nih.gov)
Title : CDC lab analysis suggests new coronavirus may cause SARS Corporate Authors(s) : Centers for Disease Control and Prevention (U.S.);United States. (cdc.gov)
Vaccines have been introduced which generate robust immune responses against SARS-CoV-2 and also provide effective protection particularly against the development of severe disease ( 1 , 2 ). (frontiersin.org)
Said the study's lead author, Nguyen Thi Thanh Nga of WCS's Viet Nam Program: "We know that SARS-like coronaviruses (SARS-CoV-2 and SARS-CoV-1) can cause serious disease in humans. (wcs.org)
Severe acute respiratory syndrome (SARS) is an infectious disease caused by a newly identified human coronavirus (SARS-CoV). (cdc.gov)
A vaccine (or vaccines) against SARS-CoV-2 would help develop community immunity against the virus and thus prevent the spread and recurrence of the disease at the population level. (canada.ca)
Canada, more specifically Toronto, Ontario (yellow), is the fifth-ranked area, although community transmission of SARS now appears to be contained, according to the US Centers for Disease Control and Prevention. (medscape.com)
SUMMARY Severe acute respiratory syndrome (SARS), the first severe new infectious disease of this millennium, caused widespread public disruption. (who.int)
SARS virus could hide in some animal or vere acute respiratory syndrome (SARS), environmental reservoir and resurface the first severe and easily transmissible when conditions again become favourable new infectious disease of the new millenni- for spread to humans. (who.int)
The Centers for Disease Control and Pre- able progress was achieved in the following vention (CDC) defines a "suspected case" months in understanding its epidemiology of SARS as a person with onset of fever and clinical features. (who.int)
Coronavirus disease 2019 or (COVID-19) was a mere that resulted in over 6.4 million deaths [3]. (who.int)

Investors are bracing for economic fallout from the spread of a new coronavirus that first emerged in the Chinese city of Wuhan. (cnbc.com)
But the new coronavirus - believed to have originated in Wuhan city - has struck China at a time when its economy has grown larger and established greater connections with the world . (cnbc.com)
There have been numerous online claims that the Wuhan Institute of Virology is connected to the coronavirus outbreak. (aap.com.au)
With the threat of the Wuhan coronavirus already in Singapore, people have started to reminisce how dark that time was for the whole island, especially when quarantine was put in place. (alvinology.com)
Here's a Reddit thread where Singaporeans both young and old reminisce about the SARS outbreak in light of the Wuhan coronavirus. (alvinology.com)
Circulating viruses similar to the Wuhan (ancestor strain) of SARS-CoV-2 has not yet been conclusively demonstrated in an intermediary animal reservoir. (hopkinsguides.com)

Some animal coronaviruses evolve (mutate) and are passed from animals to humans. (medlineplus.gov)

This virus resembles other serious human coronavirus types MERS and SARS in that all belong to the "beta" subgrouping of virus. (medicinenet.com)
The CDC notes that MERS and SARS both began as infections in bats before mutating to infect humans. (medicinenet.com)
However the link between bats and viruses, including coronaviruses such as MERS and SARS, has been documented before and since the 2010 study. (aap.com.au)

SARS -CoV-2, the virus that causes COVID -19, has infiltrated every country and put global public health and the economy at risk. (lernerbooks.com)
The full genomes of all human coronaviruses were aligned to identify regions (red) that might code for lethal differences in the virus that causes COVID-19 as well as SARS and MERS. (nih.gov)
A team of researchers from the National Library of Medicine (NLM), part of the National Institutes of Health, identified genomic features of SARS-CoV-2, the virus that causes COVID-19, and other high-fatality coronaviruses that distinguish them from other members of the coronavirus family. (nih.gov)
SARS-CoV-2 , the coronavirus that causes COVID-19, binds to a receptor called ACE2, which plays a number of roles in regulating blood pressure, blood volume, and inflammation. (scitechdaily.com)

Two strains of the virus have caused outbreaks of severe respiratory diseases in humans: severe acute respiratory syndrome coronavirus 1 (SARS-CoV or SARS-CoV-1), which caused the 2002-2004 outbreak of severe acute respiratory syndrome (SARS), and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is causing the ongoing pandemic of COVID-19. (wikipedia.org)
Some analysts said the impact could be more severe than the 2003 SARS outbreak, which wiped out 0.5 to 1 percentage points of China's growth that year, according to various estimates. (cnbc.com)
As authorities in China race to contain the spread of a new coronavirus that has killed hundreds, investors are bracing for global economic fallout that some analysts said could be more severe than the SARS outbreak in 2003. (cnbc.com)
As with the SARS outbreak 17 years ago, the spread of the new coronavirus is likely to first hit consumer spending. (cnbc.com)
was identified in 2003 as the cause of an outbreak of severe acute respiratory syndrome (SARS) that began in China near the end of 2002. (msdmanuals.com)
The "2002 to 2003 outbreak" refers to SARS, which affected 26 countries in that period . (aap.com.au)
When the March 2003 outbreak of the Severe Acute Respiratory Syndrome or SARS coronavirus hit Singapore thanks to Esther Mok in Tan Tock Seng hospital, most of our readers were much younger. (alvinology.com)
What was the SARS outbreak like when you were younger? (alvinology.com)
Since the 2002-2003 outbreak of SARS, which initially began in the Guangdong province of southern China but eventually involved more than 8000 persons worldwide (see the image below), global efforts have virtually eradicated SARS as a threat. (medscape.com)
Dr Nabarro says that leaders in South Asia have moved rapidly to try and contain the outbreak because they remember the damage caused by Severe Acute Respiratory Syndrome (SARS) in 2002. (imperial.ac.uk)

SARS patients' typical initial symptoms include fever, cough, and headache, similar to many acute viral respiratory infections. (cdc.gov)
These coronaviruses that cause severe respiratory infections are transmitted from animals to humans (zoonotic pathogens). (msdmanuals.com)
Coronaviruses are a large family of viruses that range from the common cold to serious infections such as Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS), according to the World Health Organisation (WHO). (aap.com.au)
In the past few decades, there has been rapid spread of numerous severe viral infections, including human immunodeficiency virus (HIV), influenza A, severe acute respiratory syndrome (SARS), Ebola and Zika. (canada.ca)
Mild coronavirus infections, such as the common cold, will go away in a few days with rest and self care at home . (medlineplus.gov)
Severe coronavirus infections may require hospitalization and breathing support. (medlineplus.gov)
Coronavirus for common human respiratory coronavirus infections. (hopkinsguides.com)

Severe acute respiratory syndrome-related coronavirus (SARSr-CoV or SARS-CoV) is a species of virus consisting of many known strains phylogenetically related to severe acute respiratory syndrome coronavirus 1 (SARS-CoV-1) that have been shown to possess the capability to infect humans, bats, and certain other mammals. (wikipedia.org)
Only recently have strains of SARS-related coronavirus been observed to have evolved into having been able to make the cross-species jump from bats to humans, as in the case of the strains SARS-CoV-1 and SARS-CoV-2. (wikipedia.org)
The emergence of severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome (MERS)-CoV underscores the threat of cross-species transmission events leading to outbreaks in humans. (nature.com)
While many kinds of coronavirus infect animals, there are only seven known types that infect humans. (medicinenet.com)
The type of coronavirus that infects humans was first identified in the 1960s. (medicinenet.com)
The latest coronavirus discovered that infects humans is known as COVID-19, as it was first identified in 2019. (medicinenet.com)
Like other types of coronavirus, it began in other animals before being transmitted to humans. (peta.org.uk)
A second library consisted of 244,000 peptides covering the full proteomes of all viruses known to infect humans, including endemic seasonal coronaviruses (HCoV-229E, HCoV-OC43, HCoV-NL63, HCoV-HKU1), SARS-CoV, and MERS-CoV. (scienceboard.net)
Coronaviruses that cause harmless colds in humans were discovered more than 50 years ago. (phys.org)
We were able to identify several features that are not found in less virulent coronaviruses and that could be relevant for pathogenicity in humans. (nih.gov)
He also is exploring how the decoy receptor bonds to other coronaviruses with the potential to become future pandemics if they cross from bats to humans. (scitechdaily.com)
However, 7 types of coronaviruses are known to cause illness in humans. (msdmanuals.com)
Southeast Asia hosts a high diversity of wildlife and an extensive wildlife trade that puts humans in direct contact with wild hosts of SARS-like coronaviruses. (sflorg.com)
The binding affinity for the ACE2 receptors with the spike protein of SARS-CoV-2 across eight different species compared to humans (the blue baseline). (scitechdaily.com)
There are many other coronaviruses circulating in animals, but they haven't spread to humans. (medlineplus.gov)
Currently, there is no evidence to suggest that SARS-CoV-2 can infect aquatic food animals (e.g. finfish, crustaceans, mol uscs, amphibians) and therefore these animals do not play an epidemiological role in spreading COVID-19 to humans. (who.int)

The genome of SARS-CoV is 29,727 nucleotides in length, and the genome organization is similar to that of other coronaviruses. (cdc.gov)
10 genome equivalents of SARS-CoV. (cdc.gov)
To improve the ability to detect SARS-CoV safely and reduce the risk of eliciting false-negative results caused by genome sequence variations, we established three individual real-time RT-PCR assays. (cdc.gov)
SARSr-CoV is similar to other coronaviruses in that its genome expression starts with translation by the host cell's ribosomes of its initial two large overlapping open reading frames (ORFs), 1a and 1b, both of which produce polyproteins. (wikipedia.org)
A phylogenetic tree based on whole-genome sequences of SARS-CoV-1 and related coronaviruses is: A phylogenetic tree based on whole-genome sequences of SARS-CoV-2 and related coronaviruses is: The morphology of the SARS-related coronavirus is characteristic of the coronavirus family as a whole. (wikipedia.org)
Being an experienced coronavirologist, I knew that one has to inspect the special regions of the SARS genome when trying to understand this virus," he says. (phys.org)
Using integrated comparative genomics and machine learning techniques, the researchers compared the genome of the SARS-CoV-2 virus against the genomes of other members of the coronavirus family and identified protein features that are unique to SARS-CoV-2 and two other coronavirus strains with high fatality rates, SARS-CoV and MERS-CoV. (nih.gov)
We quantified variation explained by regions of the CoV genome across different CoV viruses including, SARS-CoV-2, Middle East respiratory syndrome coronavirus (MERS-CoV), other severe acute respiratory syndrome coronavirus SARS-CoV (SARS-related), and bat-derived severe acute respiratory syndrome (SARS)-like coronaviruses (Bat-SL-CoV). (academic-accelerator.com)

Such genomic regions and their protein products might be linked to the extraordinary pathogenicity of SARS coronavirus and its cousin, the COVID-19 virus SARS-CoV-2. (phys.org)
This crisis prompts an urgent need to understand the evolutionary history and genomic features that contribute to the rampant spread of SARS-CoV-2. (nih.gov)
Retrieve, view, and download SARS coronavirus genomic and protein sequences. (nih.gov)

When it emerged in 2002/2003, the SARS coronavirus was the first coronavirus found to cause severe pneumonia in infected people. (phys.org)
SARS for SARS-CoV-1 virus has not been known to circulate since 2002-2003. (hopkinsguides.com)

Persons interested in viewing published GenBank information on SARS-CoV (Urbani strain) sequences may do so at the website of the National Center for Biotechnology Information, National Library of Medicine www.ncbi.nlm.nih.gov . (cdc.gov)
The accession number for the sequence of SARS-CoV (Urbani strain) is AY278741. (cdc.gov)
In WIV1, three of these residues vary from the epidemic SARS-CoV Urbani strain, but they were not expected to alter binding to ACE2 ( Supplementary Fig. 1a,b and Supplementary Table 1 ). (nature.com)
After 21 days of booster vaccinations, mice were intranasally transduced with non-replicating adenovirus-expressing hACE2 (human angiotensin-converting enzyme 2) followed by SARS-CoV-2 wild-type (wt) Washington-1 strain challenge after five days. (news-medical.net)
Further, using adjusted log-log multiple regression, we modeled the association between each strain of HCoV and SARS-CoV-2 antibodies. (frontiersin.org)
5 million people have been infected with the strain of coronavirus SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus-2) globally. (academic-accelerator.com)

Bats are reservoir species for numerous viruses including coronaviruses. (pasteur.fr)

several strains have been identified in Himalayan palm civets, which were likely ancestors of SARS-CoV-1. (wikipedia.org)
The results indicate that group 2b viruses encoding the SHC014 spike in a wild-type backbone can efficiently use multiple orthologs of the SARS receptor human angiotensin converting enzyme II (ACE2), replicate efficiently in primary human airway cells and achieve in vitro titers equivalent to epidemic strains of SARS-CoV. (nature.com)
To do this, they used epitope-level assays that have the potential to provide additional information about immune cross-reactivity between other coronavirus strains and SARS-CoV-2. (scienceboard.net)
They compared SARS-CoV-2 reactivity profiles with patterns of peptides from the second constructed peptide library which included endemic human coronavirus strains. (scienceboard.net)

In a recent study posted to the bioRxiv * preprint server, researchers investigated whether immunity against seasonal human coronavirus (CoV) spike (S) proteins of HKU1, OC43, NL63, or 229E could protect against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in vitro . (news-medical.net)
Researchers have hypothesized that anti-seasonal CoV immunity could partially protect against COVID-19 and that SARS-CoV-2 vaccinations induce back-boosting effects against the seasonal β-CoV S proteins. (news-medical.net)
Mice were vaccinated with NL63, 229E, OC43, HKU1, and SARS-CoV-2 S proteins in prime-boost regimens. (news-medical.net)
The first library the researchers constructed was focused on SARS-CoV-2 and contained 2,107 peptides representing spike and nucleocapsid proteins with an average of 38 peptides covering each amino acid position. (scienceboard.net)
They detected significantly more SARS-CoV-2 peptides enriched in convalescent samples compared to controls for both spike and nucleocapsid proteins. (scienceboard.net)
Coronavirus researchers led by Professor Rolf Hilgenfeld of the University of Luebeck and PD Dr. Albrecht von Brunn of the Ludwig-Maximilian Universitaet (LMU) in Munich have discovered how SARS viruses enhance the production of viral proteins in infected cells, so that many new copies of the virus can be generated. (phys.org)
However, in cells infected with SARS-CoV or SARS-CoV-2, the messenger RNA molecules that code for host proteins are selectively destroyed by a viral protein named Nsp1. (phys.org)
Interaction studies of this kind between coronavirus proteins and proteins of the infected human cell will help us understand how the viruses change key functions of the cell to their own benefit," says Hilgenfeld. (phys.org)
The more efficient the process, the better the coronavirus can create the proteins it needs to replicate. (scitechdaily.com)
Methods: Blood samples were tested for IgG antibodies against SARS-CoV-2 nucleocapsid (N) and spike (S) proteins. (kcl.ac.uk)

Many detection methods have been used or reported for the diagnosis and/or surveillance of SARS-CoV-2. (biorxiv.org)
Testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was confirmed through molecular detection by real-time polymerase chain reaction, serologic testing for IgM and electron microscope examination of lung samples. (lu.se)
Conclusions: The detection of SARS-CoV-2 in postmortem examination can be an incidental or contributory finding which highlights the value of autopsy examination to determine the exact cause of death in controversial cases. (lu.se)

Diagnostic tests may not be available for all kinds of coronavirus. (medlineplus.gov)

These assays-the first tools to detect SARS-CoV in patients with SARS-were based on the short stretches of viral sequence identified as the RNA-directed RNA polymerase of a new microbe. (cdc.gov)
Mice were euthanized after three days and five days of SARS-CoV-2 to obtain their pulmonary tissues for viral load quantification by classic plaque assays, and their antibody titers were determined. (news-medical.net)
Jian Lei et al, The SARS‐unique domain (SUD) of SARS‐CoV and SARS‐CoV‐2 interacts with human Paip1 to enhance viral RNA translation, The EMBO Journal (2021). (phys.org)
These data suggest that the 80R human monoclonal antibody may be a useful viral entry inhibitor for the emergency prophylaxis and treatment of SARS, and that the ACE2-binding site of S1 could be an attractive target for subunit vaccine and drug development. (nih.gov)
The Efficacy Assessment of Disinfecting Substances Alternative to Alcohol for Use Against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) (Ministry of Economy, Trade and Industry) has judged virucidal efficacy of disinfecting substances against SARS-CoV-2 on the basis of the criterion set at a 99.99% or more reduction in viral titer. (nichia.co.jp)

The emergence of SARS-CoV heralded a new era in the cross-species transmission of severe respiratory illness with globalization leading to rapid spread around the world and massive economic impact 3 , 4 . (nature.com)
Coronaviruses are a large family of viruses that cause respiratory illness ranging in severity from the common cold to fatal pneumonia. (msdmanuals.com)

Researchers from Northern Arizona University (NAU) and the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, conducted a study that sought to understand how coronaviruses stimulate the human immune system and conduct a deeper dive on the inner workings of the antibody response. (scienceboard.net)
The researchers used a synthetic biology approach called PepSeq to resolve antibody responses to a range of human-infecting coronaviruses. (scienceboard.net)
The data generated using PepSeq allowed for broad characterization of the antibody response in individuals recently infected with SARS-CoV-2 compared with those of individuals exposed only to previous coronaviruses that now are widespread in human populations," said lead author, Jason Ladner, PhD, an assistant professor at NAU's Pathogen and Microbiome Institute, in a statement. (scienceboard.net)
The team identified antibody reactivity against 229 SARS-CoV-2 peptides in convalescent and 95 SARS-CoV-2 peptides in negative control samples. (scienceboard.net)
We have identified eight recombinant human single-chain variable region fragments (scFvs) against the S1 domain of spike (S) protein of the SARS-CoV from two nonimmune human antibody libraries. (nih.gov)
Are higher antibody levels against seasonal human coronaviruses associated with a more robust humoral immune response after SARS-CoV-2 vaccination? (frontiersin.org)
SARS-CoV-2 antibody titres were highest among double-vaccinated, infected women. (kcl.ac.uk)

The N166 epitope, while not correlated to any endemic coronaviruses, what highly conserved with SARS-CoV peptides in the analysis. (scienceboard.net)
The SARS-CoV-2 belongs to the coronavirus family, which also includes common endemic coronaviruses (HCoVs). (frontiersin.org)
Serological studies have documented evidence of antibodies to other human endemic coronaviruses (HCoV's), which include leading causes of the "common cold" ( 8 ). (frontiersin.org)

The researchers hypothesized that cross-reactivity of antibodies can be explained by exposure to conserved protein regions of related endemic human coronaviruses. (scienceboard.net)
In particular, the insertions in the spike protein are predicted, from protein structure analysis, to facilitate the recognition of the coronavirus receptors on human cells and the subsequent penetration of the virus into those cells. (nih.gov)
One scFv 80R efficiently neutralized SARS-CoV and inhibited syncytia formation between cells expressing the S protein and those expressing the SARS-CoV receptor angiotensin-converting enzyme 2 (ACE2). (nih.gov)
In blue, the human ACE2 protein and in grey, the coronavirus spike protein. (scitechdaily.com)
We have identified mutations on the S-protein that dramatically reduce the capacity of SARS-CoV-2 to enter into the cell, protecting the host from catching COVID-19 ," says Javier Delgado, researcher at the CRG and first author of the study. (scitechdaily.com)
Coronavirus (SARX-CoV) membrane protein is fused to a His-tag. (enzolifesciences.com)

There are many different coronaviruses. (msdmanuals.com)

Is There a Vaccine for COVID-19 (SARS-CoV-2)? (medicinenet.com)
So far, no vaccine has been developed for the newly discovered coronavirus. (medicinenet.com)
Further, mice were vaccinated 21 days post-boost with a SARS-CoV-2 S-encoded LNP (lipid nanoparticle)-formulated and nucleoside-modified mRNA vaccine encoding the SARS-CoV-2 S. An unvaccinated control group was added for comparative evaluation. (news-medical.net)
Anti-HCoV-229E and HCoV-NL63 antibodies were unaffected by vaccination, and higher levels were associated with significantly higher COVID-19 vaccine-induced SARS-COV-2 antibodies. (frontiersin.org)

Recently, a new coronavirus was identified as the suspected causative agent of an increased number of atypical pneumonia cases reported from Hong Kong, Singapore, Vietnam, and Canada ( 1 - 4 ). (cdc.gov)
Some coronaviruses cause severe illness that can lead to pneumonia, and even death. (medlineplus.gov)
Severe acute respiratory syndrome (SARS) is a serious form of pneumonia . (medlineplus.gov)
[ 11 , 12 ] The CDC recommends that patients suspected of or confirmed as having SARS receive the same treatment that would be administered if they had any serious, community-acquired pneumonia. (medscape.com)
Guangdong cases to be consistent with the chest radiographic findings of pneumonia, definition of SARS after its team was per- acute respiratory distress syndrome mitted on 2 April 2003 to visit the province. (who.int)

The SARSr-CoV species is a member of the genus Betacoronavirus and of the subgenus Sarbecovirus (SARS Betacoronavirus). (wikipedia.org)
SARS-related coronavirus is a member of the genus Betacoronavirus (group 2) and monotypic of the subgenus Sarbecovirus (subgroup B). Sarbecoviruses, unlike embecoviruses or alphacoronaviruses, have only one papain-like proteinase (PLpro) instead of two in the open reading frame ORF1ab. (wikipedia.org)
The HR2 epitope is highly conserved between SARS-CoV-2, SARS-CoV, and HCoV-OC43 (all members of the betacoronavirus genera), but not with HCoV-229E which is an alphacoronavirus. (scienceboard.net)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a betacoronavirus in the sarbecovirus family, has caused significant global morbidity and mortality. (frontiersin.org)
Origin is uncertain, although bats are implicated as this virus is closely related by genetic analysis to bat SARS -like coronavirus (genus Betacoronavirus , subgenus Sarbecovirus ). (hopkinsguides.com)
SARS-CoV-2 belongs to the family Coronaviridae and genus Betacoronavirus . (who.int)

SARS-CoV-2 S vaccination induced high reactivity for the homologous S with little cross-reactivity for HKU-1 and OC43 but no α-CoV S reactivity. (news-medical.net)

With the end of the federal COVID-19 Public Health Emergency (PHE) on May 11, 2023, CDC will no longer receive data needed to publish Community Transmission levels for SARS-CoV-2. (cdc.gov)

What Are the Symptoms of Coronavirus COVID-19 (SARS-CoV-2)? (medicinenet.com)
Many researchers hypothesize that the host of symptoms associated with COVID-19 may stem from the coronavirus binding to ACE2 and keeping it from doing its job. (scitechdaily.com)
The fear over any symptoms associated with SARS made going out in public difficult for anyone. (alvinology.com)
Laboratories can use the Panther Fusion system to test a single patient sample for SARS-CoV-2 and other respiratory viruses that can cause similar symptoms, increasing efficiency and clinical insight. (hologic.com)
Exposure to MERS-CoV, SARS-CoV, and SARS-CoV-2 can cause severe symptoms. (medlineplus.gov)
There are four common Coronaviruses that circulate and cause typical symptoms of the common cold in addition to two more severe Coronaviruses that cause SARS and MERS. (cdc.gov)

Bats serve as the main host reservoir species for the SARS-related coronaviruses like SARS-CoV-1 and SARS-CoV-2. (wikipedia.org)
A team of scientists have identified coronaviruses closely related to SARS-CoV-2 from two bats sampled in Cambodia more than a decade ago. (sflorg.com)
The study found bats "may be candidates as the natural host" of the SARS coronavirus. (aap.com.au)
And a January 2019 paper also examined how bats are able to harbour many types of coronavirus. (aap.com.au)
Many coronaviruses originate in bats, which can infect other animals. (medlineplus.gov)

Subsequent publications demonstrated that this new coronavirus was detectable in patients with severe acute respiratory syndrome (SARS) ( 5 , 6 ), classified according to the World Health Organization's case definition ( 7 ). (cdc.gov)
SARS, which stands for severe acute respiratory syndrome, first emerged in China's Guangdong province before spreading to other countries. (cnbc.com)
A real-time reverse transcription-polymerase chain reaction (RT-PCR) assay was developed to rapidly detect the severe acute respiratory syndrome-associated coronavirus (SARS-CoV). (nih.gov)
It is caused by the SARS-CoV-2 virus (severe acute respiratory syndrome coronavirus 2). (medlineplus.gov)
Objective: To determine severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seroprevalence in pregnancy in an inner-city setting and assess associations with demographic factors and vaccination timing. (kcl.ac.uk)
Testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was confirmed through. (lu.se)

Recently, the sequence variations of SARS-CoV during the first epidemic phases in China in 2003 were reported. (cdc.gov)
In addition, the sequence analysis of isolates from recent SARS patients in China in 2004 has shown that 98.8%-99.4% of the 3,768 bases of S gene, 99% of 658 bases of M gene, and 99% of 1,068 bases of N gene are isogenous with those submitted to public databases, which date back to the first epidemic in spring 2003 ( 14 ). (cdc.gov)
The SARS-related coronavirus was one of several viruses identified by the World Health Organization (WHO) in 2016 as a likely cause of a future epidemic in a new plan developed after the Ebola epidemic for urgent research and development before and during an epidemic towards diagnostic tests, vaccines and medicines. (wikipedia.org)
Here are five charts that show how China's economy has changed since the SARS epidemic. (cnbc.com)
All you want to know about SARS-CoV-2, the Covid-19 epidemic and the research projects conducted at the Institut Pasteur is on this webpage. (pasteur.fr)
More than three years after the start of the COVID-19 epidemic, mathematical modeling is still providing us with valuable insights, as shown in a recent study on household transmission of SARS-CoV-2 by the Hong Kong University School of Public Health and the Institut Pasteur/Université Paris Cité. (pasteur.fr)
During the SARS epidemic, 348 people were killed in China and nearly 800 died worldwide. (michaelsavage.com)
One Reddit user said that while for some people it was "business as usual," the taxi drivers were the ones most hit by the SARS epidemic. (alvinology.com)

Initial results show the test can distinguish between antibodies produced in response to SARS-CoV-2 and four other coronaviruses with 100-percent accuracy. (sciencedaily.com)
Can antibodies to seasonal coronaviruses protect against SARS-CoV-2? (scienceboard.net)
We further demonstrate that these cross-reactive antibodies preferentially bind to endemic coronavirus peptides, suggesting that the response to SARS-CoV-2 at these regions may be constrained by previous coronavirus exposure. (scienceboard.net)
We created scatter plots and performed correlation analysis to estimate the extent of the linear relationship between HCoVs and SARS-CoV-2 anti-spike antibodies. (frontiersin.org)
From the adjusted log-log multiple regression model, higher HCoV-229E and HCoV-NL63 anti-spike IgG antibodies were associated with increased SARS-COV-2 anti-spike IgG antibodies. (frontiersin.org)

The sequence data confirmed that SARS-CoV is a previously unrecognized coronavirus. (cdc.gov)

The SARS-related coronavirus is an enveloped, positive-sense, single-stranded RNA virus. (wikipedia.org)
Using the SARS-CoV reverse genetics system 2 , we generated and characterized a chimeric virus expressing the spike of bat coronavirus SHC014 in a mouse-adapted SARS-CoV backbone. (nature.com)
Scientists believe that there is a subset of individuals with SARS-CoV-2 who are three times more likely to spread the virus to other individuals than the average person. (pasteur.fr)
The official name of the virus is SARS-CoV-2. (medicinenet.com)
The virus that causes it was named SARS-CoV-2. (medicinenet.com)
The coronavirus is an RNA virus. (medicinenet.com)
Mit einer derartigen antiviralen Wirkung hatte die Erstautorin der Studie, Rayhane Nchioua, nicht gerechnet: „Wir waren schon überrascht, wie effektiv dieser zelluläre Faktor SARS-CoV-2 hemmt und hoffen, dass unsere Ergebnisse helfen werden, Immuntherapien gegen dieses Virus zu verbessern", sagt die Doktorandin am Institut für Molekulare Virologie des Universitätsklinikums Ulm. (idw-online.de)
Bei SARS-CoV-2 treten sie offenbar gehäuft in einigen Bereichen auf, die für die Vermehrung des Virus unentbehrlich sind. (idw-online.de)
By analyzing how these interacted with the coronavirus, he found a combination of three mutations that made a receptor that bound to the virus 50 times more strongly, making it a much more attractive target for the virus. (scitechdaily.com)
Las condiciones ambientales influyen en el proceso de inactivación del virus, que se verá acelerado al aumentar la temperatura y la humedad relativa. (univadis.es)
realizar con esmero una buena higiene de manos tras tocar superficies y con una solución que contenga al menos un 60% de alcohol reduce e inactiva al virus en la piel en 15 segundos. (univadis.es)
Este ARNm tiene instrucciones para producir una proteína de superficie que el virus SARS-CoV-2 utiliza para entrar en las células. (univadis.es)
El sistema inmunitario de la persona receptora, tras reconocer esta proteína como extraña, produce anticuerpos y activa los linfocitos T, lo que la protegerá cuando entre en contacto con el virus SARS-CoV-2. (univadis.es)
En este proceso no está involucrado ningún virus vivo ni material genético que altere el núcleo de las células. (univadis.es)
De wetenschappelijke gemeenschap vecht tegen de tijd voor de productie van een vaccin, maar het is moeilijk om een veilig en effectief product op de markt te brengen zo snel als het virus zich verspreidt. (kanker-actueel.nl)
Considering the severity of the health crisis that SARS-CoV-2 has caused worldwide, and with so little known about the virus, our focus should be drawn towards approaches that can bring better development outcomes in a relatively short period of time. (canada.ca)
MARLBOROUGH, Mass.--(BUSINESS WIRE)-- Hologic, Inc. (Nasdaq: HOLX) announced today that it plans to launch a new Aptima® molecular assay to detect the SARS-CoV-2 virus that will run on its market-leading Panther® system. (hologic.com)
The latest virus, SARS-CoV-2, is also suspected to originate from animals. (medlineplus.gov)
1 While the existence, transmissibility, treatment, and potential impact of severe acute respiratory coronavirus SARS-CoV-2 were real questions since the virus was first recognized in December, 2019,2 much of the media coverage was driven by global public health concerns and international/national political posturing. (academic-accelerator.com)
Aquatic food animals and their products, like any other surface, may potential y become contaminated with SARS-CoV-2, especial y when handled by people who are infected with the virus. (who.int)

however, there are important differences in the 14 residues that bind human ACE2, the receptor for SARS-CoV, including the five that are critical for host range: Y442, L472, N479, T487 and Y491 (ref. 7 ). (nature.com)
The identified features correspond with the high fatality rate of these coronaviruses, as well as their ability to move from animal to human hosts. (nih.gov)
Common human coronaviruses cause mild to moderate illnesses, such as the common cold . (medlineplus.gov)
Human coronaviruses that cause the common cold spread from person-to-person. (medlineplus.gov)

Recently, nested and real-time reverse transcription-polymerase chain reaction (RT-PCR) assays to detect SARS-CoV have been published ( 5 , 8 ). (cdc.gov)
The real-time RT-PCR assay was more sensitive than a conventional RT-PCR assay or culture isolation and proved suitable to detect SARS-CoV in clinical specimens. (nih.gov)
With the goal of improving sensitivity and accommodate various application settings, we developed a multiplex-PCR-based method comprised of 172 pairs of specific primers, and demonstrated its efficiency to detect SARS-CoV-2 at low copy numbers. (biorxiv.org)

However, the genomes of RNA viruses, including those of coronaviruses, tend to vary over time and with location ( 9 - 12 ). (cdc.gov)
Comparisons of the RNA genomes of innocuous coronaviruses with those of the SARS coronavirus permitted researchers to identify a region that only occurred in the latter, and was called the "SARS-unique domain" (SUD). (phys.org)

We hypothesized that immunity to HCoVs would be associated with stronger immunogenicity from SARS-CoV-2 vaccines. (frontiersin.org)
SARS-CoV-2 ferritin nanoparticle vaccines elicit broad SARS coronavirus immunogenicity. (bvsalud.org)

Subsequently, sequences from several SARS-CoV isolates were determined, and all of these sequences were closely related, as would be expected during the clustered outbreaks in 2003. (cdc.gov)

In the present study, researchers evaluated the immune protective effects of anti-seasonal CoV S immunity against COVID-19-causing SARS-CoV-2 in mice and whether the pre-existing immune levels to seasonal CoVs impacted the immune protection conferred by SARS-CoV-2 vaccinations. (news-medical.net)
In total the researchers analyzed 55 COVID-19 convalescent and 69 SARS-CoV-2-negative blood samples using the PepSeq libraries. (scienceboard.net)
This innovative research is critical to improve researchers' understanding of SARS-CoV-2 and aid in the response to COVID-19," said NLM Director Patricia Flatley Brennan, R.N., Ph.D. "Predictions made through this analysis can inform possible targets for diagnostics and interventions. (nih.gov)
The researchers also tested the different species 'codon adaptation index' - which is how efficient the coronavirus is at commandeering a cell's machinery once it has entered. (scitechdaily.com)

Stocks Recovered From the Ebola and SARs Scares… Will They Recover From Coronavirus? (gainspainscapital.com)
Is coronavirus worse than Ebola or SARS? (gainspainscapital.com)

Pre-existing seasonal CoV S immunity provided negligible immune protection against SARS-CoV-2 but did not show any negative effects on vaccination-induced anti-SARS-CoV-2 immunity. (news-medical.net)
However, there are likely other processes which impact an individual's immune protection to SARS-COV-2, including past exposures and pre-existing immunity to other similar viruses ( 1 , 6 , 7 ). (frontiersin.org)

OC43 vaccination induced robust anti-OC43 S activity, lower activity for HKU-1 S and SARS-CoV-2, and negligible activity for α-CoVs. (news-medical.net)
HKU1 S vaccination led to strong activity for the homologous S and lesser titers for SARS-CoV-2 S and OC43. (news-medical.net)
Samples were tested for anti-spike IgG against SARS-CoV-2, HCoV-229E, HCoV-HKU1, HCoV-NL63, and HCoV-OC43 antigens. (frontiersin.org)

Next week, Hologic expects to begin distributing a Research Use Only (RUO) version of its Aptima SARS-CoV-2 test to hospital, public health and reference laboratories certified under the Clinical Laboratory Improvement Amendments (CLIA) to perform high complexity tests. (hologic.com)
The clinical course of SARS generally follows a typical pattern. (medscape.com)
High-resolution computed tomography (HRCT) scanning is controversial in the evaluation of SARS but may be considered when SARS is a strong clinical possibility despite normal chest radiographs. (medscape.com)

Notably, coronaviruses other than SARS-CoV and SARS-CoV-2 do not use this mechanism, which may therefore provide a possible explanation for the much higher pathogenicity of the SARS viruses. (phys.org)

The finding suggests that SARS-CoV-2 related viruses likely circulate via multiple Rhinolophus species. (sflorg.com)

The coronavirus is a big family of pathogens. (medicinenet.com)
So obviously from the standpoint of this presentation, as you know we have reviewed the over 4,000 patents that have been issued around SARS coronavirus and we have done a very comprehensive review of the financing of all of the manipulations of coronavirus which t gave rise to SARS as a subclade of the Beta coronavirus family. (flutrackers.com)
This study confirms the presence of coronaviruses in the SARS-CoV family in trafficked pangolins in Viet Nam. (wcs.org)
Coronaviruses are a family of viruses. (medlineplus.gov)
It is from the same family of viruses as SARS-CoV, which is why they have similar names. (medlineplus.gov)

If I look at the past history of the way coronaviruses behave, then I have to come to a logical conclusion that they are very species-specific and a coronavirus does not just jump from an animal to a person. (earthfiles.com)

Although ACE2 binds to SARS-CoV-2, it is not optimized for that purpose, which means that subtle mutations to the receptor could make it bind more strongly. (scitechdaily.com)

To characterize the placental pathologic features of SARS-CoV-2-infected placentas, irrespective of fetal-maternal transmission, and to examine the frequency of C4d activation in such cases. (allenpress.com)

Anatomy3

Organisms18

Diseases7

Chemicals and Drugs10

Phenomena and Processes5

Information Science4

Health Care2

Geographicals3

Infection38

Pandemic11

202010

Disease24

Wuhan6

Animal coronaviruses1

MERS and SARS3

Causes COVID-194

Outbreak10

Infections7

Humans16

Genome8

Genomic3

20022

Strain6

Viruses including cor1

Strains4

Proteins10

Detection3

Kinds of coronavirus1

Viral5

Respiratory illness2

Antibody7

Endemic coronaviruses3

Protein6

Different coronaviruses1

Vaccine4

Pneumonia5

Betacoronavirus6

Cross-reactivity1

20231

Symptoms6

Bats5

Severe Acute Re6

Epidemic8

Antibodies5

Previously unrecognized1

Virus20

Human4

Detect3

Genomes2

Vaccines2

Outbreaks1

Researchers4

Ebola2

Immunity2

OC433

Clinical3

Pathogenicity1

Circulate1

Family5

Species1

Receptor1

Transmission1