Novel bumped kinase inhibitors target proteins inhibitor protein. Medical search. Frequent questions

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Anatomy13

Cell Line, Tumor Cell Line Cells, Cultured Mitochondria, Heart Submitochondrial Particles Tumor Cells, Cultured Cell Nucleus HeLa Cells Cytosol Fibroblasts Liver 3T3 Cells COS Cells

Organisms9

Cattle Eleusine Rats, Sprague-Dawley Rabbits Escherichia coli Tenebrio Mice, Knockout Mice, Inbred C57BL Streptomycetaceae

Diseases2

Angioedema Leukemia, Myelogenous, Chronic, BCR-ABL Positive

Chemicals and Drugs168

Small Molecule Libraries Protein Inhibitors of Activated STAT Protein Kinase Inhibitors Phosphatidylethanolamine Binding Protein Protein Kinases Enzyme Inhibitors Phosphatidylinositol 3-Kinases Protein-Serine-Threonine Kinases 5-Lipoxygenase-Activating Protein Inhibitors Proteins Protein Kinase C Protein-Tyrosine Kinases SUMO-1 Protein src-Family Kinases Small Ubiquitin-Related Modifier Proteins Carrier Proteins Cyclin-Dependent Kinase Inhibitor p27 Cyclin-Dependent Kinases Calcium-Calmodulin-Dependent Protein Kinases Intracellular Signaling Peptides and Proteins Cyclin-Dependent Kinase Inhibitor p21 Cyclic AMP-Dependent Protein Kinases p38 Mitogen-Activated Protein Kinases Pyrimidines Mitogen-Activated Protein Kinase 1 Recombinant Proteins Cholesterol Ester Transfer Proteins Phosphoprotein Phosphatases Proton-Translocating ATPases Recombinant Fusion Proteins Mitogen-Activated Protein Kinase 3 Mitogen-Activated Protein Kinase Kinases Protein Phosphatase 1 JNK Mitogen-Activated Protein Kinases Adenosine Triphosphate Proto-Oncogene Proteins Quinolines Indoles Cell Cycle Proteins RNA, Messenger Mitogen-Activated Protein Kinases Calcium Protease Inhibitors Aurovertins p21-Activated Kinases Piperazines Benzamides DNA-Binding Proteins Cyclic AMP Receptor Protein-Tyrosine Kinases Plant Proteins Antineoplastic Agents Cyclins rho-Associated Kinases CDC2 Protein Kinase Trypsin Inhibitors Isoenzymes Phosphoproteins Transcription Factors Quinazolines MAP Kinase Kinase Kinases Receptor, Epidermal Growth Factor Pyrroles Aurora Kinases Androgen-Binding Protein Extracellular Signal-Regulated MAP Kinases Complement C1 Inactivator Proteins Phosphotransferases (Alcohol Group Acceptor)Proto-Oncogene Proteins c-akt Pyridines Staurosporine Chromones Nuclear Proteins Creatine Kinase MAP Kinase Kinase 1 Genistein Casein Kinase II Ribosomal Protein S6 Kinases Androstadienes Morpholines CDC2-CDC28 Kinases Casein Kinases Peptides eIF-2 Kinase DNA Primers Cysteine Proteinase Inhibitors Tyrosine NF-kappa B Tumor Suppressor Proteins Cyclin-Dependent Kinase Inhibitor Proteins Pyruvate Kinase Ubiquitin-Protein Ligases Flavonoids RNA, Small Interfering MAP Kinase Kinase 4 DNA, Complementary Calcium-Binding Proteins 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine Peptide Fragments Trypsin Thymidine Kinase Cyclin-Dependent Kinase Inhibitor p57 Glycogen Synthase Kinase 3 1-Phosphatidylinositol 4-Kinase I-kappa B Proteins Cystatins I-kappa B Kinase Myosin-Light-Chain Kinase Membrane Proteins Macromolecular Substances Protein Kinase C-delta Diacylglycerol Kinase Molecular Chaperones Cyclin-Dependent Kinase 2 Microtubule-Associated Proteins Alpha-Globulins Protein Kinase C-alpha Tetradecanoylphorbol Acetate Aurora Kinase A Adenosine Triphosphatases Focal Adhesion Kinase 1 Thiazoles Ubiquitins Trans-Activators Tyrphostins Serine Proto-Oncogene Proteins c-abl Calmodulin Imidazoles AMP-Activated Protein Kinases Janus Kinase 2 Nitriles Focal Adhesion Protein-Tyrosine Kinases STAT3 Transcription Factor Fusion Proteins, bcr-abl TOR Serine-Threonine Kinases Isoquinolines Ribosomal Protein S6 Kinases, 90-kDa Ovomucin Pertussis Toxin Placental Hormones Cysteine Endopeptidases Ribonuclease, Pancreatic Lipoxygenase Inhibitors Calcium-Calmodulin-Dependent Protein Kinase Type 2 STAT1 Transcription Factor Bacterial Proteins MAP Kinase Kinase 2 Ligases 5-Lipoxygenase-Activating Proteins MAP Kinase Kinase Kinase 1 Cyclin-Dependent Kinase Inhibitor p16 Glycoproteins Adenosine Kinase Uracil-DNA Glycosidase Myosin-Light-Chain Phosphatase Phosphotyrosine Aurora Kinase B Cyclic GMP-Dependent Protein Kinases Proto-Oncogene Proteins c-raf Carbazoles Adaptor Proteins, Signal Transducing Endo-1,4-beta Xylanases DNA Sulfonamides Nerve Tissue Proteins Protein Kinase C-epsilon Cyclin-Dependent Kinase Inhibitor p18

Analytical, Diagnostic and Therapeutic Techniques and Equipment17

Models, Molecular Blotting, Western Transfection Electrophoresis, Polyacrylamide Gel Two-Hybrid System Techniques Models, Biological Cloning, Molecular Sequence Alignment Crystallography, X-Ray Reverse Transcriptase Polymerase Chain Reaction Drug Design Precipitin Tests Mutagenesis, Site-Directed Immunoblotting Chromatography, Gel Chromatography, High Pressure Liquid Immunohistochemistry

Phenomena and Processes42

Protein Binding Amino Acid Sequence Phosphorylation MAP Kinase Signaling System Signal Transduction Kinetics Binding Sites Enzyme Activation Protein Structure, Tertiary Sumoylation Mutation Apoptosis Transfection Sequence Homology, Amino Acid Base Sequence Substrate Specificity Protein Conformation Dose-Response Relationship, Drug Cell Proliferation Cell Cycle Gene Expression Regulation Molecular Weight Transcription, Genetic Time Factors Cell Division Structure-Activity Relationship Protein Processing, Post-Translational Up-Regulation Promoter Regions, Genetic Plasmids G1 Phase Protein Structure, Secondary Drug Resistance, Neoplasm Hydrogen-Ion Concentration Gene Expression Hot Temperature Transcriptional Activation Cell Survival Down-Regulation Protein Transport Dimerization Gene Expression Regulation, Enzymologic

Disciplines and Occupations2

Drug Design Immunohistochemistry

Information Science3

Molecular Sequence Data Amino Acid Sequence Base Sequence

Health Care1

Hot Temperature

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Information Science Health Care

Small Molecule Libraries Protein Inhibitors of Activated STAT Protein Kinase Inhibitors Phosphatidylethanolamine Binding Protein Protein Kinases Enzyme Inhibitors Phosphatidylinositol 3-Kinases Protein-Serine-Threonine Kinases 5-Lipoxygenase-Activating Protein Inhibitors Protein Binding Molecular Sequence Data Amino Acid Sequence Phosphorylation Proteins MAP Kinase Signaling System Signal Transduction Protein Kinase C Protein-Tyrosine Kinases SUMO-1 Protein src-Family Kinases Small Ubiquitin-Related Modifier Proteins Carrier Proteins Cyclin-Dependent Kinase Inhibitor p27 Kinetics Cyclin-Dependent Kinases Calcium-Calmodulin-Dependent Protein Kinases Intracellular Signaling Peptides and Proteins Binding Sites Cyclin-Dependent Kinase Inhibitor p21 Enzyme Activation Protein Structure, Tertiary Cyclic AMP-Dependent Protein Kinases Cell Line, Tumor Sumoylation Cell Line Cattle Models, Molecular Cells, Cultured Blotting, Western p38 Mitogen-Activated Protein Kinases Mutation Pyrimidines Apoptosis Mitogen-Activated Protein Kinase 1 Transfection Recombinant Proteins Cholesterol Ester Transfer Proteins Sequence Homology, Amino Acid Base Sequence Phosphoprotein Phosphatases Proton-Translocating ATPases Substrate Specificity Recombinant Fusion Proteins Mitochondria, Heart Protein Conformation Dose-Response Relationship, Drug Mitogen-Activated Protein Kinase 3 Mitogen-Activated Protein Kinase Kinases Protein Phosphatase 1 JNK Mitogen-Activated Protein Kinases Adenosine Triphosphate Submitochondrial Particles Proto-Oncogene Proteins Quinolines Indoles Cell Cycle Proteins Electrophoresis, Polyacrylamide Gel RNA, Messenger Mitogen-Activated Protein Kinases Calcium Eleusine Protease Inhibitors Tumor Cells, Cultured Aurovertins p21-Activated Kinases Angioedema Piperazines Benzamides DNA-Binding Proteins Cell Proliferation Two-Hybrid System Techniques Cyclic AMP Cell Cycle Receptor Protein-Tyrosine Kinases Models, Biological Plant Proteins Antineoplastic Agents Cyclins rho-Associated Kinases Gene Expression Regulation CDC2 Protein Kinase Trypsin Inhibitors Cloning, Molecular Molecular Weight Isoenzymes Transcription, Genetic Phosphoproteins Transcription Factors Quinazolines MAP Kinase Kinase Kinases

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