• This category includes pneumonia, bronchitis, bacteremia, and meningitis caused by any one of the 83 serotypes of Streptococcus pneumoniae . (nationalacademies.org)
  • Pneumococcal pneumonia is the most common form of community-acquired pneumonia in the elderly, accounting for up to 60 percent of cases 14 , 34 , 35 , 36 , 37 , 52 and for up to 20 percent of nosocomial pneumonias. (nationalacademies.org)
  • 10 , 52 Pneumococcal bacteremia, which is more easily proven than pneumococcal pneumonia, occurs in up to one-quarter of cases of pneumococcal pneumonia. (nationalacademies.org)
  • 26 , 32 Although pneumococcal pneumonia does not result in permanent lung damage, complications from bacteremia and meningitis are common and can damage other organ systems. (nationalacademies.org)
  • Despite this long-held view, there is some debate about the role of appropriate outcome in serious infections, in particular with nosocomial pneumonia. (karger.com)
  • Zyvox (linezolid) has received Federal Drug Administration approval for treatment of Vancomycin Resistant Enterococcus (VRE) infections, nosocomial pneumonia, community-acquired pneumonia, and various skin/skin structure infections. (ny.gov)
  • Quinupristin-dalfopristin has been shown to be effective in the management of documented severe infections caused by vancomycin-resistant E. faecium , nosocomial pneumonia, and infections related to the use of intravascular catheters. (aafp.org)
  • This class of antibiotics is an important addition to the options available for the treatment of severe infections caused by gram-positive organisms, including nosocomial pneumonia and infections related to the use of intravascular catheters. (aafp.org)
  • Colonization of airway does predispose to Nosocomial Pneumonia--23 per cent colonized develop pneumonia versus 4 per cent not colonized. (revolutionpharmd.com)
  • In 1960's, outbreaks of Nosocomial Pneumonia were related to contaminated respiratory therapy equipment. (revolutionpharmd.com)
  • Hospital-acquired pneumonia (HAP) was the second most common nosocomial infection and the leading cause of death in critical illness patients. (researchsquare.com)
  • Streptococcus pneumoniae has become a leading cause of bacteremia, pneumonia, meningitis, and otitis media in the United States. (cdc.gov)
  • Nosocomial pneumonia caused by Staphylococcus aureus (methicillin-susceptible and -resistant strains) or Streptococcus pneumoniae (including multi-drug resistant strains). (com.bd)
  • Community-acquired pneumonia caused by Streptococcus pneumoniae (including multi-drug resistant strains) including cases with concurrent bacteremia or Staphylococcus aureus (methicillin-susceptible strains only). (com.bd)
  • P seudomonas aeruginosa is an opportunistic P. aeruginosa infections are often resistant to pathogen that often causes nosocomial infections treatment, 4 and carbapenem use has been strongly as- (e.g. pneumonia, bacteraemia and urinary sociated with resistance. (who.int)
  • I specifically addressed only cellulitis, acute bacterial sinusitis, community-acquired pneumonia, nosocomial pneumonia / ventilator-associated pneumonia , complicated urinary tract infections, and complicated intra-abdominal infections. (medscape.com)
  • Methicillin-resistant Staphylococcus aureus (MRSA) remains an important nosocomial pathogen, although the organism has increasingly been recognized as a significant cause of community-acquired infection around the world. (canada.ca)
  • Continued surveillance of ITU patients and occasional environmental sampling has proved to be important in preventing and controlling subsequent outbreaks of infection by this increasingly important nosocomial pathogen. (microbiologyresearch.org)
  • Xanthomonas maltophilia has emerged as an important nosocomial pathogen, particularly in immunocompromised patients. (northwestern.edu)
  • Streptococcus pneumoniae can be a nosocomial pathogen in elderly, debilitated patients. (elsevierpure.com)
  • Khomeini Hospital was reviewed to identify patients who had nosocomial bacteraemia between 1 May 1999 and 31 May 2001 and identify the pathogen responsible and its resisitance to antibiotics. (who.int)
  • Pseudomonas aeruginosa is an opportunistic pathogen that often causes nosocomial infections resistant to treatment. (who.int)
  • Vancomycin-Resistant Enterococcus faecium infections including cases with concurrent bacteremia. (com.bd)
  • The incidence of nosocomial bacteraemia in PIVC was one of the several catheter-related complications that were tested. (medgadget.com)
  • Incidence rates and density rates are reported for nosocomial infections, hospital onset bacteremia, urinary tract infection, device associate, and procedure associated infections. (navy.mil)
  • Nosocomial infection (NI) incidence is related to severity of underlying disease , i.e. patients with a 50 per cent chance of death in 1 year have a 40 per cent chance of NI, whereas a patient with a non-fatal illness have only a 3 per cent chance of NI. (revolutionpharmd.com)
  • In five years we studied 56 episodes of pneumococcal bacteremia. (elsevierpure.com)
  • The mortality directly related to the pneumococcal bacteremia was also higher (52% vs 39%), but not significantly. (elsevierpure.com)
  • Mixed pneumococcal bacteremia with gram-negative bacilli was more frequent in nosocomial infections. (elsevierpure.com)
  • Population-based studies have shown that the elderly sustain the highest pneumococcal bacteremia rates of any population group-50 per 100,000 persons over the age of 65, 36 , 37 which is more than three times greater than the rates for younger persons. (nationalacademies.org)
  • Death rates from pneumococcal bacteremia range from 20 to 80 percent, increasing with age and complications. (nationalacademies.org)
  • The studies in regard to nosocomial pneumonias are not as conclusive as those with bacteremias. (karger.com)
  • Historically, isolates resistant to oxacillin (commonly referred to as MRSA) were resistant to most agents other than vancomycin, but these isolates were limited to nosocomial infections. (medscape.com)
  • According to data from the National Nosocomial Infection Surveillance System (1989 to 1993), 1 the percentage of nosocomial enterococcal isolates that are resistant to vancomycin (Vancocin) has increased from 0.3 percent to 8 percent. (aafp.org)
  • Complications occur when the salmonella bacteria make their way into the bloodstream ( bacteremia ). (yourdictionary.com)
  • Not only are nosocomial infec- nurses disinfect skin with 70% alcohol fol- tions increasing, they are more frequently lowed by 2% povidone-iodine before col- being caused by pathogenic bacteria that lecting blood samples. (who.int)
  • Blot S, Vandewoude K, De Bacquer D, Colardyn F: Nosocomial bacteremia caused by antibiotic-resistant gram-negative bacteria in critically ill patients: Clinical outcome and length of hospitalization. (karger.com)
  • Serratia species appear to be common environmental organisms, and this helps to explain the large number of nosocomial infections due to these bacteria. (scienceopen.com)
  • Epidemics of nosocomial urinary tract infection caused by multiply resistant gram-negative bacilli: Epidemiology and control. (cdc.gov)
  • The clinical significance of positive blood cultures in the 1990s: A prospective comprehensive evaluation of the microbiology, epidemiology, and outcome of bacteremia and fungemia in adults. (cdc.gov)
  • The CNISP is a collaborative effort involving hospitals across the country participating as members of the Canadian Hospital Epidemiology Committee (a sub-committee of the Association of Medical Microbiology and Infectious Diseases Canada), and the Nosocomial and Occupational Infections Section, Public Health Agency of Canada. (canada.ca)
  • Enterobacter and Serratia can cause bacterial infection of the blood ( bacteremia ), particularly in patients with weakened immune systems. (yourdictionary.com)
  • [ 42 , 43 ] S aureus endocarditis may require a prolonged course of antibiotics, although recent studies suggest it may be possible to switch many patients with endocarditis or complicated bacteremia to oral therapy after an initial course of 10 to 14 days of IV antimicrobial therapy. (medscape.com)
  • [ 55 ] The addition of daptomycin to cefazolin or cloxacillin did not result in improved outcomes in patients with MSSA bacteremia. (medscape.com)
  • The urinary tract is the most common site of nosocomial infection, accounting for more than 40% of the total number reported by acute-care hospitals and affecting an estimated 600,000 patients per year (1). (cdc.gov)
  • Infection was associated with bacteremia in 13% of the patients. (canada.ca)
  • Adult patients with monomicrobial 3GCRE bacteraemia receiving carbapenems within 24 h were included at two hospitals in Thailand. (altmetric.com)
  • Empirical carbapenems were prescribed in 427/1032 (41%) patients with 3GCRE bacteraemia, of whom 221 received ertapenem and 206 received class 2 carbapenems. (altmetric.com)
  • Since many nosocomial infections are caused by multiply antibiotic-resistant strains of S. marcescens, this increases the danger to hospitalized patients, and hospital personnel should be vigilant in preventing nosocomial outbreaks due to this organism. (scienceopen.com)
  • Approximately 5 per cent of all patients develop a nosocomial infection as a result of being hospitalized, with an average resultant stay in-hospital of 13 days longer than controls. (revolutionpharmd.com)
  • In this retrospective analysis, the clinical and epidemiologic factors as well as the response to therapy in patients with xanthomonas bacteremia are examined. (northwestern.edu)
  • During a 6-year period, 24 patients had bacteremia with this organism. (northwestern.edu)
  • Results: One hundred thirty-one (21.7%) patients acquired at least one nosocomial infection following cardiac surgery. (wustl.edu)
  • Identification of morbidity and mortality risk factors for AB bacteremia in emergency department (ED) patients may provide ways to improve the clinical outcomes of these patients. (hku.hk)
  • METHODS: The records for 51 patients with AB bacteremia and 51 patients without AB infection were collected and matched in a retrospective case-control study between 2013 and 2015 in a single-center ED. Risk factors were analyzed by Chi-square and multivariate logistic regression statistical models. (hku.hk)
  • The presence of a CVC was associated with higher morbidity and mortality in patients with AB bacteremia. (hku.hk)
  • Avoiding CVC insertions may improve outcomes in ED patients with AB bacteremia. (hku.hk)
  • A critical finding of our metaanalysis is that the number of deaths was 2-fold higher among patients with bacteremia caused by CRE than among patients with bacteremia caused by CSE. (cdc.gov)
  • However, a significant difference in death rates was not detected between the 2 compared groups in studies reporting on patients with undetermined infections, patients with infections other than bacteremia, or patients among whom the percentage of bacteremia cases was low. (cdc.gov)
  • Therefore, it could be suggested that the higher rate of death among patients with CRE infections, compared with CSE infections, is due to the higher rate of death among patients with bacteremia caused by CRE. (cdc.gov)
  • Treatment of methicillin-susceptible S aureus (MSSA) bacteremia with cefazolin has been shown to improve survival rates and decrease toxicity in comparison to antistaphylococcal penicillins. (medscape.com)
  • We conducted a GWAS to identify common variants associated with acquisition of S. aureus bacteremia (SAB) resulting from healthcare contact. (biomedcentral.com)
  • In September 1999, the U.S. Food and Drug Administration labeled quinupristin-dalfopristin (Synercid) for use in the treatment of serious or life-threatening infections associated with vancomycin-resistant Enterococcus faecium bacteremia and complicated skin and skin structure infections caused by methicillin-susceptible Staphylococcus aureus and Streptococcus pyogenes (group A streptococcus). (aafp.org)
  • Saint S. Clinical and economic consequences of nosocomial catheter-related bacteriuria. (cdc.gov)
  • We reviewed electronic medical records of the 1102 inpatients with COVID-19, and excluded inpatients with incomplete records on admission, or co-infection before admission, or nosocomial infections less than 48 hours after admission, or secondary urinary tract infections. (researchsquare.com)
  • Study objective: To evaluate the relationship between nosocomial infections and clinical out comes following cardiac surgery, and to identify risk factors for the development of nosocomial infections in this patient population. (wustl.edu)
  • Conclusions: Nosocomial infections, which are common following cardiac surgery, are associated with prolonged lengths of hospitalization, the development of multiorgan dysfunction, and increased hospital mortality. (wustl.edu)
  • These data suggest potential interventions for the prevention of nosocomial infections following cardiac surgery that could substantially improve patient outcomes and decrease medical care costs. (wustl.edu)
  • Nosocomial infections are a prevalent cause of death and complications in critically ill children. (sccm.org)
  • however, nosocomial bacteraemia was less frequent in NICUs with low neonatal consultant provision (odds ratio 0.65, 95% CI 0.43-0.98). (nih.gov)
  • X. maltophilia bacteremia is an important cause of morbidity and mortality, and antibiotic therapy should be based on in vitro susceptibility. (northwestern.edu)
  • Primary outcomes were hospital mortality, mortality or cerebral damage, and nosocomial bacteraemia. (nih.gov)
  • In bacteremia, data are most persuasive that appropriate and timely therapy significantly influences outcomes. (karger.com)
  • Muder RR, Brennen C, Wagener MM, Goetz AM. Bacteremia in a long-term-care facility: A five-year prospective study of 163 consecutive episodes. (cdc.gov)
  • In a study of 296 consecutive MRSA bacteremia episodes, several factors were predictive of high vancomycin MIC, including age older than 50 years, prior vancomycin exposure, history of MRSA bacteremia, history of chronic liver disease, and presence of a nontunneled catheter. (medscape.com)
  • In a small study (40 subjects) with MRSA bacteremia, the combination of ceftaroline plus daptomycin was found to have lower in-hospital mortality rate as compared to vancomycin or daptomycin monotherapy. (medscape.com)
  • Examples are bacteremia and meningitis, especially severe in children with health conditions that increase their susceptibility to infection. (yourdictionary.com)
  • Two days later, on we report the case of a patient with no- day 8 of her hospitalization, the patient sensitive to ceftriaxone, meropenem, socomial rotavirus-associated gastro- showed deterioration of clinical signs, amikacin, ciprofloxacin, but resistant to enteritis complicated by Enterobacter with lethargy, fever (39 °C), tachy- amoxicillin-clavulanic acid and cefuro- cloacae bacteraemia who was treated cardia (170 beats/min. (who.int)
  • and body tempera- based on the presence of leukocytosis, ative bacteraemia as a complication ture 36.4 °C. Neurological examina- thrombocytopaenia, metabolic acido- of rotavirus-associated gastroenteritis tion showed developmental delay, mild sis, increased serum CRP level, pro- has been reported in healthy children hypotonia and increased leg muscle longed PT, PTT and increased level of (2) . (who.int)
  • In burns, the region below the eschar can become heavily infiltrated with organisms, serving as a focus for subsequent bacteremia-an often lethal complication. (msdmanuals.com)
  • Leibovici L, Paul M, Poznanski O, et al: Monotherapy versus beta-lactam-aminoglycoside combination treatment for gram-negative bacteremia: A prospective, observational study. (karger.com)
  • We describe the clinical and microbiological characteristics of GPAC bacteraemia. (lu.se)
  • GPAC-bacteraemia is a condition with significant mortality mainly affecting elderly persons with comorbidities. (lu.se)
  • The phylogenetic landscape and nosocomial spread of the multidrug-resistant opportunist Stenotrophomonas maltophilia. (applied-maths.com)
  • Towards optimizing carbapenem selection in stewardship strategies: a prospective propensity score-matched study of ertapenem versus class 2 carbapenems for empirical treatment of third-generation cephalosporin-resistant Enterobacterales bacteraemia. (altmetric.com)
  • Enterococci, leading causes of nosocomial bacteremia, surgical wound infection, and urinary tract infection, are becoming resistant to many, and sometimes all standard therapies. (cdc.gov)
  • Sensitivity analyses were consistent regardless of aetiological pathogens, septic shock, source of infection, nosocomial acquisition, lactate levels or albumin levels. (altmetric.com)
  • Surveillance for MRSA in sentinel Canadian hospitals participating in the Canadian Nosocomial Infection Surveillance Program (CNISP) has been ongoing since its inception in January 1995. (canada.ca)
  • Hospital-Onset MRSA Bacteremia Rates Are Significantly Correlated With Sociodemographic Factors: A Step Toward Risk Adjustment. (duke.edu)
  • Conclusions: GPAC bacteraemia is much more common than previously reported. (lu.se)
  • Main outcome measures: Occurrence of nosocomial infections, multiorgan dysfunction, hospital mortality, and risk factors for the acquisition of nosocomial infections. (wustl.edu)
  • Methods: A retrospective population-based study of GPAC bacteraemia 2012-2016 in southern Sweden was performed. (lu.se)
  • Bacteremia is not necessary for the development of septic shock. (atsu.edu)
  • The enteric Gram-negative bacteraemia in the ABON® immunochromatographic blood culture of the patient at the time infants with rotavirus infection who test (Abon Biopharm Ltd). of clinical deterioration (on day 8) were treated with corticosteroids for yielded E. cloaca . (who.int)
  • Weinstein JW, Mazon D, Pantelick E, Reagan-Cirincione P, Dembry LM, Hierholzer WJ,Jr. A decade of prevalence surveys in a tertiary-care center: Trends in nosocomial infection rates, device utilization, and patient acuity. (cdc.gov)
  • Noskin, GA & Grohmann, SM 1992, ' Xanthomonas maltophilia bacteremia: An analysis of factors influencing outcome ', Infectious Diseases in Clinical Practice , vol. 1, no. 4, pp. 230-236. (northwestern.edu)
  • There was no difference in outcome on the basis of sex, age, underlying disease, polymicrobial bacteremia, total leukocyte count, or absolute neutrophil count. (northwestern.edu)