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  • inhibits
  • Competition for the binding sites of enzymes that participate in essential biosynthetic processes and subsequent incorporation of these biomolecules into nucleic acids , inhibits their normal tumor cell function and triggers apoptosis , or the cell death process. (wikipedia.org)
  • similar
  • In the case of normal ALT the investigators do not know if the natural history in co-infected patients is similar than the mono-infected patients, and also the response of the treatment. (clinicaltrials.gov)
  • commonly
  • Antimetabolites, particularly mitomycin C (MMC), are commonly used in America and Japan as an addition to trabeculectomy , a surgical procedure to treat glaucoma . (wikipedia.org)
  • organs
  • Although this agent is one of the most successful in the treatment of cancer, it produces major toxicities to normal cells and organs at the concentrations necessary for effective treatment of malignancies. (medscape.com)
  • different
  • However, since they are slightly different that the normal bases after they are incorporated into the DNA, the DNA production is halted and the cell dies. (wikipedia.org)
  • damage
  • Repair of DNA damage is a normal and vital process in the cell. (lls.org)
  • We conclude that normal cells and mice can be protected against chemotherapy-dependent damage by reducing circulating IGF-I levels and by a mechanism that involves downregulation of proto-oncogene signals. (aacrjournals.org)
  • production
  • A precondition for normal absorption of thiamin is sufficient production of stomach hydrochloric acid. (dsm.com)