• The widespread administration of the Haemophilus influenzae type b vaccine has led to the predominance of non-typable H. influenzae (NTHi). (biomedcentral.com)
  • However, the occurrence of invasive NTHi infection based on gynecologic diseases is still rare. (biomedcentral.com)
  • With the high uptake in the uterus with 67 Ga scintigraphy, she was diagnosed with invasive NTHi infection. (biomedcentral.com)
  • Although NTHi bacteremia consequent to a microabscess in adenomyosis is rare, this case emphasizes the need to consider the uterus as a potential source of infection in patients with underlying gynecological diseases, including an invasive NTHi infection with no known primary focus. (biomedcentral.com)
  • In Japan, a recent nationwide population-based surveillance study revealed that NTHi and H. influenzae type f became the predominant isolates associated with invasive H. influenzae infection after the introduction of the Hib vaccine [ 10 ]. (biomedcentral.com)
  • While previous reports have established the urogenital tract as a potential cause of invasive H. influenzae infection, no reports have described a specific association of NTHi infection with adenomyoma. (biomedcentral.com)
  • Here, we report a case of invasive NTHi infection associated with a massive adenomyosis in an immunocompetent Japanese woman. (biomedcentral.com)
  • In our proposed project, you would investigate expression regulation in clinically significant bacterium non-typeable Haemophilus influenzae (NTHi). (lu.se)
  • In a new study, the derivatives proved to be effective at clearing a type of bacteria called Nontypeable Haemophilus influenzae (NTHi), which often plagues people with inflammatory diseases like chronic obstructive pulmonary disease (COPD). (futurity.org)
  • Anti-inflammatory drugs are the most common treatment, but, because they suppress the immune system, can put people with the disease at risk for secondary infections, most commonly NTHi bacterial infections. (futurity.org)
  • Researchers tested the effectiveness of an inhalable omega-3 derivative to prevent NTHi lung infections in mice. (futurity.org)
  • We show increase in invasive nontypeable Haemophilus influenzae (NTHi) infection from 2017-2018 among HIV-infected men who have sex with men in metropolitan Atlanta, Georgia. (robertpetit.com)
  • Airways inflammation in type-2 low asthma or COPD is potentially driven by persistent bacterial colonization of the lower airways by bacteria such as non-encapsulated Haemophilus influenzae (NTHi). (ox.ac.uk)
  • We studied NTHi infection of primary human bronchial epithelial cells (PBECs), primary nasal epithelial cells (NECs) and epithelial cell lines from upper and lower airways. (ox.ac.uk)
  • We found NTHi was internalized within PBECs at 6 h, but live intracellular infection did not persist at 24 h. (ox.ac.uk)
  • Currently, non-encapsulated H. influenzae , also called non-typeable H. influenzae (NTHi), is responsible for the majority of cases of otitis media, sinusitis, and pneumonia in patients that have already been immunized with the vaccine. (statpearls.com)
  • They can also help to differentiate true NTHi from Haemophilus haemolyticus and from those H. influenzae strains that possess a complete or partial capsule focus. (statpearls.com)
  • The majority of invasive H. influenzae disease is now caused by non-typeable H. influenzae (NTHi) in all age groups in the US. (statpearls.com)
  • Although non-typeable Haemophilus influenzae (NTHi) is less likely to be a fatal bacterium, invasive NTHi infection has been reported to increase worldwide. (bvsalud.org)
  • This study presents a case of sudden death of a child with invasive NTHi infection and underlying immunoglobulin G2 (IgG2) deficiency. (bvsalud.org)
  • IgG2 subclass deficiency contributed to the development of invasive NTHi infection. (bvsalud.org)
  • The invasive NTHi infection might present a risk of sudden death, particularly for immunocompromised children. (bvsalud.org)
  • Nontypeable Haemophilus influenzae (NTHI) may play a role as an infectious trigger in the pathogenesis of chronic obstructive pulmonary disease (COPD). (nih.gov)
  • NTHI infection in lung tissues obtained from COPD patients and controls was studied in vivo and using an in vitro model. (nih.gov)
  • We show for the first time the expression of the TGF pseudoreceptor BAMBI in the human lung, which is upregulated in response to NTHI infection in COPD lung tissue in vivo and in vitro. (nih.gov)
  • Haemophilus influenzae (NTHi) and Moraxella catarrhalis vaccine are two other common bacteria that cause ear and sinus infections. (ascentist.com)
  • Recently, the National Institutes of Health has issued a license for the first clinical trials for a nontypeable Haemophilus influenzae (NTHi) vaccine. (ascentist.com)
  • Non-typeable Haemophilus influenzae (NTHi) significantly contribute to human disease including chronic obstructive pulmonary disorder (COPD). (findaphd.com)
  • Nontypeable Haemophilus influenzae (NTHI), a common colonizer of lungs of patients with chronic obstructive pulmonary disease (COPD), can enhance expression of the cellular receptor intercellular adhesion molecule 1 (ICAM-1), which in turn can be used by major group human rhinoviruses (HRVs) for attachment. (maastrichtuniversity.nl)
  • Interestingly, release of IL-6 and IL-8 after RSV, but not HRV, infection was synergistically increased in hi-NTHI-pretreated BEAS-2B cells. (maastrichtuniversity.nl)
  • Furthermore, hi-NTHI pretreatment may enhance the inflammatory response to RSV infection, suggesting that preexisting bacterial infections might exaggerate inflammation during secondary viral infection. (maastrichtuniversity.nl)
  • Although H. influenzae type b (Hib) is a notoriously virulent serotype of this species [ 4 ], the introduction of routine conjugate Hib vaccination led to a decrease in the number of cases of Hib infection [ 5 ]. (biomedcentral.com)
  • Phylogenetic Structure and Comparative Genomics of Multi-National Invasive Haemophilus influenzae Serotype a Isolates. (cdc.gov)
  • Evaluating a Cluster and the Overall Trend of Invasive Haemophilus influenzae Serotype b in Alaska 2005-2019. (cdc.gov)
  • Genomic Diversity of Haemophilus influenzae Serotype a in an Outbreak Community, Alaska 2018. (cdc.gov)
  • H. influenzae serotype a (Hia) increasingly noted as a cause of severe, invasive infection. (hopkinsguides.com)
  • Most bacterial infections produce clinical signs of infection in the mother, but infections may not be evident if the membranes rupture shortly after inoculation, similar to drainage of an abscess. (medscape.com)
  • Here, we review emerging mechanisms into why COPD patients are susceptible to chronic bacterial infections and highlight dysregulated inflammation and production of reactive oxygen species (ROS) as central causes. (frontiersin.org)
  • Our biggest concern with patients who have COPD is bacterial infections, which often put their lives at risk," says Richard Phipps, professor of environmental medicine and director of the lung biology and disease program at the University of Rochester Medical Center. (futurity.org)
  • Next to viral infection, also bacterial infections can be involved in the development of acute exacerbations. (biomedcentral.com)
  • It is a common cause of a variety of invasive and non-invasive bacterial infections. (statpearls.com)
  • Haemophilus influenzae type b (Hib) vaccine, click here . (wikidoc.org)
  • The Hib conjugate vaccine is effective for protection against capsular polysaccharide type 'b' and has decreased the rate of Hib infections to a greater extent. (statpearls.com)
  • Current H. influenzae vaccines target only H. influenzae type b, which was believed to be the cause of 95 percent of all H. influenzae infections in the pre-vaccine era. (nvic.org)
  • Prior to the introduction of the Hib vaccine in the mid-1980's, H. influenzae type b was responsible for most cases of meningitis, a serious infection of the membranes that cover the spinal cord and brain, which is the most common clinical presentation of invasive disease. (nvic.org)
  • Following the introduction of the Hib vaccine, the burden of invasive H. influenzae disease has shifted from children to adults, and most particularly seniors over the age of 65. (nvic.org)
  • NVIC encourages you to become fully informed about Haemophilus Influenzae Type B (Hib) and the Hib vaccine by reading all sections in the Table of Contents, which contain many links and resources such as the manufacturer product information inserts, and to speak with one or more trusted health care professionals before making a vaccination decision for yourself or your child. (nvic.org)
  • Nasopharyngeal carriage of otitis media pathogens in infants receiving 10-valent non-typeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV10), 13-valent pneumococcal conjugate vaccine (PCV13) or a mixed primary schedule of both vaccines: A randomised controlled trial. (edu.au)
  • Acute lower respiratory infections in Indigenous infants in Australia's Northern Territory across three eras of pneumococcal conjugate vaccine use (2006-15): a population-based cohort study. (edu.au)
  • Interchangeability, immunogenicity and safety of a combined 10-valent pneumococcal Haemophilus influenzae protein D conjugate vaccine (Synflorix) and 13-valent-PCV (Prevenar13) schedule at 1-2-4-6 months: PREVIX_COMBO, a 3-arm randomised controlled trial. (edu.au)
  • Otitis media outcomes of a combined 10-valent pneumococcal Haemophilus influenzae protein D conjugate vaccine and 13-valent pneumococcal conjugate vaccine schedule at 1-2-4-6 months: PREVIX_COMBO, a 3-arm randomised controlled trial. (edu.au)
  • We examined quantitative and functional antibody response to COVID-19 vaccination in infection-naive subjects with and without sarcoidosis.MethodsOur prospective cohort study recruited 14 subjects with biopsy-proven sarcoidosis and 27 age-sex matched controls who underwent a two-shot series of the BNT162b2 mRNA vaccine at the University of Illinois at Chicago. (journaltocs.ac.uk)
  • Haemophilus influenzae b vaccine in the binding protein (PBP) is also of concern cultured on chocolate agar + polyvita- industrialized world and the decreased as it relates to 20% of non-encapsulated min supplement + bacitracin (Bio-rad, incidence of invasive diseases [1], Hae- strains isolated in Europe [9]. (who.int)
  • Kastrin T , Paragi M , Kolman J , Cizman M , Kraigher A , Gubina M , Characterisation of invasive Haemophilus influenzae isolates in Slovenia, 1993-2008. (cdc.gov)
  • Infection experiments were performed with two different clinical isolates. (nih.gov)
  • Haemophilus influenzae type b (Hib) is bacteria that commonly cause bacterial meningitis and pneumonia and the leading cause of other invasive diseases as septic arthritis (joint infection), epiglottitis (infection and swelling of the epiglottis) and cellulites (rapidly progressing skin infection which usually involves face, head, or neck). (who.int)
  • Overview of Pneumonia Pneumonia is acute inflammation of the lungs caused by infection. (msdmanuals.com)
  • While often used as a synonym for pneumonia , the rubric of lower respiratory tract infection can also be applied to other types of infection including lung abscess , acute bronchitis , and emphysema . (bionity.com)
  • There are a number of acute and chronic infections that can affect the lower respiratory tract, the focus of this paper is to look at the two most common infections, Bronchitis and Pneumonia, as identified by the Therapeutic guidelines. (bionity.com)
  • 4] H influenzae and M catarrhalis are of increasing importance in both community acquired pneumonia (CAP) and acute exacerbation of chronic bronchitis (AECB) while the importance of S pneumoniae is declining. (bionity.com)
  • Pneumonia is a serious infection of the small bronchioles and alveoli that can involve the pleura. (bionity.com)
  • HIV appears to be a risk factor for developing invasive disease due to H. influenzae type b, especially bacteremic pneumonia. (hopkinsguides.com)
  • The sensitivity of Gram stain and culture probably ~50% in pts with H. influenzae pneumonia. (hopkinsguides.com)
  • H. influenzae responsible for 3-40% of HIV-related bacterial pneumonia. (hopkinsguides.com)
  • and nontypeable H. influenzae invasive illness, while most commonly associated with infections such as conjunctivitis, otitis media, sinusitis, and pneumonia, still has the potential to cause serious invasive H. influenzae disease. (nvic.org)
  • One of the most common and potentially serious bacteria to cause ear and sinus infections and pneumonia and meningitis is the pneumococcus. (ascentist.com)
  • INTRODUCTION - Community-acquired pneumonia (CAP) is defined as an acute infection of the pulmonary parenchyma in a patient who has acquired the infection in the community, as distinguished from hospital-acquired (nosocomial) pneumonia. (medilib.ir)
  • Pathological inflammation is worsened by chronic bacterial lung infections and susceptibility to recurrent acute exacerbations of COPD (AECOPD), typically caused by viral and/or bacterial respiratory pathogens. (frontiersin.org)
  • Another major consequence of susceptibility to infection is that people with underlying severe disease frequently develop acute exacerbations of COPD (AECOPD). (frontiersin.org)
  • Introduction: Primary antibody deficiencies (PAD) are inborn defects of the immune system that result in increased susceptibility to infections. (bvsalud.org)
  • This study suggests that E-cigarette vapour has the potential to increase susceptibility to pneumococcal infection. (ersjournals.com)
  • To assess antibioticstrategies, here we measured the antibiotic susceptibility of Pnc and Haemophilus influenzae (Hi) isolated fromnasopharyngeal flora in infants with acute otitis media in the 13-valent PCV (PCV13) era in France. (medicinelakex1.com)
  • Haemophilus influenzae strains in north Lebanon in both invasive and non-invasive disease and to determine the susceptibility pattern and the mechanism of resistance to -lactams [-lactamase-producing strains and -lactamase-negative ampicillin resistant (BLNAR) strains]. (who.int)
  • They can also cause many other types of serious infections such as meningitis, epiglottitis, cellulitis, septic arthritis, and even empyema and bacteremia. (statpearls.com)
  • The first attempts at treatment, which resulted in only modest reductions in the high mortality rate of Haemophilus influenzae type b (Hib) meningitis, involved the administration of antisera generated by intrathecal inoculation of horses. (medscape.com)
  • to evaluate the efficiency of the standard influenzae may produce various clinical phenotypic identification by comparing Capsular typing syndromes including meningitis [4]. (who.int)
  • H.influenzae is a gram-negative , cocco-bacillary , facultatively anaerobic pathogenic bacterium that can cause infections in people of all ages ranging from mild, such as an ear infection, to severe, such as a bloodstream infection. (wikidoc.org)
  • Haemophilus influenzae is a pleomorphic gram-negative coccobacillus. (cdc.gov)
  • Test results on body fluids from various sites of infection that reveal small, gram-negative, pleomorphic coccobacilli with polymorphonuclear cells are strong evidence of infection. (medscape.com)
  • Haemophilus influenzae is a bacteria characterized as a small, facultatively anaerobic, pleomorphic, and capnophilic gram-negative coccobacillus of the family Pasteurellaceae. (statpearls.com)
  • Haemophilus influenzae is characterized as a small (0.3 micrometer to 1 micrometer), facultatively anaerobic, pleomorphic, and capnophilic gram-negative coccobacillus of the family Pasteurellaceae . (statpearls.com)
  • Otitis media and acute bronchitis due to H. influenzae are generally caused by nontypeable strains. (who.int)
  • Nontypeable strains are rare causes of serious infection among children but are a common cause of ear infections in children and bronchitis in adults. (who.int)
  • Infection with influenza B on the other hand did not affect cytokine production in BEAS-2B cells exposed to the different bacterial strains. (biomedcentral.com)
  • Among the bacterial species that are frequently detected during such episodes are strains of non-typeable (NT) Haemophilus influenzae , Pseudomonas aeruginosa and Streptococcus pneumoniae [ 1 ]. (biomedcentral.com)
  • Haemophilus influenzae can be divided into typeable and non-typeable strains. (bvsalud.org)
  • Non-typeable H. influenzae strains more common now than type b. (hopkinsguides.com)
  • Other Haemophilus strains ( H. aphrophilus, now called Aggregatibacter aphrophilus ) occasional cause of infection in HIV. (hopkinsguides.com)
  • Strains type a and type f increasingly identified as causing severe H. influenzae infection. (hopkinsguides.com)
  • Most infections (about two-thirds) caused by non-typeable strains. (hopkinsguides.com)
  • Strains that do not have a polysaccharide capsule are referred to as nontypeable. (nvic.org)
  • These diseases are most a Gram stain was performed for the Lebanon, while the most recent Middle often caused by non-encapsulated strains suspect colony and the identification of East data concerning the prevalence were or non-typeable Haemophilus influenzae each isolate was completed using Rapid from 2007 [10]. (who.int)
  • Çevik is Associate Editor of the Elsevier journal Clinical Microbiology and Infection. (wikipedia.org)
  • Clinical Microbiology and Infection. (wikipedia.org)
  • Frontiers in Cellular and Infection Microbiology , 12. (lu.se)
  • Elizabeth Briere] Haemophilus influenza, or Hi, are bacteria that can cause a variety of infections in children and adults. (cdc.gov)
  • Nontypeable H. influenzae commonly causes ear infections in children and bronchitis in adults, but can also cause invasive disease. (cdc.gov)
  • The epidemiology and estimated etiology of pathogens detected from the upper respiratory tract of adults with severe acute respiratory infections in multiple countries, 2014-2015. (cdc.gov)
  • However, H. influenzae type b remains rare, so immunization unwarranted in adults, including HIV+ pts. (hopkinsguides.com)
  • adults, especially seniors over the age of 65, have become more susceptible to the infection. (nvic.org)
  • A 2011 published study on H. influenzae infections in Utah found that between 1998 and 2008, over 50 percent of H. influenzae infections and 67 percent of H. influenzae related deaths occurred in adults over the age of 65. (nvic.org)
  • A 2011 published study found that between 1998 and 2008, 51 percent of invasive H. influenzae cases involved adults over the age of 65. (nvic.org)
  • Nontypeable H. influenzae also cause 30% to 52% of episodes of acute otitis media and sinusitis in children. (cdc.gov)
  • Can non-typeable Haemophilus influenzae carriage surveillance data infer antimicrobial resistance associated with otitis media? (edu.au)
  • Researchers continue to look for help for children and parents of children who suffer from the most common type of ear infection, called middle ear infection or otitis media (OM). (ascentist.com)
  • This underlying chronic infection leaves COPD patients particularly vulnerable to acute viral infections, which further destabilize host immunity to bacteria. (frontiersin.org)
  • Vaccines to prevent viral infections like the flu that can eventually lead to ear infections should be considered for children with recurring ear infections. (ascentist.com)
  • Wakabayashi H , Oda H , Yamauchi K , Abe F . Lactoferrin for prevention of common viral infections. (microbiologyresearch.org)
  • pericardiatis (infection of the sac covering the heart) and Osteomyelitis (bone infection) are less common forms of invasive disease. (who.int)
  • While invasive disease caused by H. influenzae type b (Hib) has decreased, invasive disease by non-b and nontypeable H. influenzae have increased. (nvic.org)
  • Previous studies suggest that upregulation of PAFR is a biologically plausible mechanism for the association between inhalation of toxins and vulnerability to pneumococcal infection. (ersjournals.com)
  • Despite ongoing efforts to reduce AECOPD rates with inhaled corticosteroids, COPD patients remain at heightened risk of developing serious lung infections/AECOPD, frequently leading to hospitalization and infection-dependent delirium. (frontiersin.org)
  • Evidence that long-term exposure to atmospheric particulates decreases the body's defences against bacterial and viral pathogens appear sufficient, particularly by altering the response of bronchial epithelial cells via inflammatory processes and endothelial dysfunction, and exacerbating the conditions of chronically ill patients, particularly those with COPD and asthma [8-14], and children with acute respiratory infections [15]. (bmj.com)
  • Infections of the respiratory tract are a major risk to patients with chronic respiratory diseases, such as chronic obstructive pulmonary diseases (COPD). (biomedcentral.com)
  • The majority of acute exacerbations of COPD (AECOPD) is associated with an acute respiratory infection, with viral and/or bacterial pathogens being detected in more than half of all exacerbations [ 1 , 2 ]. (biomedcentral.com)
  • Transcriptome arrays showed no significant changes of TGF-beta receptors 1 and 2 and Smad-3 expression, whereas a strong expression of BAMBI with upregulation after in vitro infection of COPD lung tissue was demonstrated. (nih.gov)
  • Furthemore, M. catarrhalis is the second most common bacterial cause of exacerbations of chronic obstructive pulmonary disease (COPD) after H. influenzae [ 10 ]. (biomedcentral.com)
  • COPD is among the top five causes of death worldwide and infections with M. catarrhalis cause 2-4 million exacerbations of COPD per annum in the United States alone [ 7 , 11 ]. (biomedcentral.com)
  • It is important to use appropriate antibiotic selection based on the infecting organism and to ensure this therapy changes with the evolving nature of these infections and the emerging resistance to conventional therapies. (bionity.com)
  • 6] Most often it is caused by viral infection and hence antibiotic therapy is not indicated in immunocompetent individuals. (bionity.com)
  • H. influenzae may be either encapsulated (typeable) or unencapsulated (nontypeable). (cdc.gov)
  • Non-b but typeable (i.e., a, c, d, e, and f) H. influenzae (hereto after referred to as non-b H. influenzae ) can cause disease similar to Hib infections. (cdc.gov)
  • Up to 80% may be carriers of non-typeable H. influenzae . (hopkinsguides.com)
  • and can be either encapsulated (typeable) or unencapsulated (nontypeable). (nvic.org)
  • Typeable H. influenzae contain a polysaccharide capsule and are identified and labeled with letters a through f . (nvic.org)
  • The spread and clinical impact of ST14CC-PBP3 type IIb/A, a clonal group of non-typeable Haemophilus influenzae with chromosomally mediated beta-lactam resistance - a prospective observational study. (blogspot.com)
  • Compounds derived from omega-3 fatty acids-like those found in salmon or sardines-might be the key to helping the body fight lung infections, a new study suggests. (futurity.org)
  • We here investigated if pre-exposure to bacteria alters the response of lung epithelial cells to subsequent viral infection. (biomedcentral.com)
  • The journal's scope extends to research on lung infections and diagnosis, inflammation and immunity, microbial pathogenesis and viral-bacterial interactions. (biomedcentral.com)
  • However, physical proximity between the patient and the ultrasound operator is a limitation in the current pandemic context, emphasising the need to implement specific infection prevention and control measures.Availability of qualified staff adequately trained to perform lung ultrasound remains a major barrier to lung ultrasound utilisation. (journaltocs.ac.uk)
  • Tracking bacterial evolution during chronic infection provides insights into how host selection pressures shape bacterial genomes. (unavarra.es)
  • This tolerance often links biofilms with persistent and chronic infection, and provides ideal conditions for the acquisition or evolution of AMR. (southampton.ac.uk)
  • There are no vaccines for non-b and nontypeable H. influenzae . (cdc.gov)
  • Before Hib vaccines became available, infections occurred nearly exclusively in children under the age of five, with the majority of infections occurring in children younger than eighteen months. (nvic.org)
  • Hib vaccines target only H. influenzae type b and offers no protection against any other type of H. influenzae infection. (nvic.org)
  • Working with the International Severe Acute Respiratory and emerging Infection Consortium (ISARIC), Çevik has looked to transfer clinical studies related to coronavirus disease to developing countries. (wikipedia.org)
  • After 24 hours of incubation at 37 °C, otic resistance of clinical H. influenzae in and children. (who.int)
  • Bronchial epithelial cells (BEAS-2B cells and primary bronchial epithelial cells) were exposed to heat-inactivated Haemophilus influenzae , Pseudomonas aeruginosa or Streptococcus pneumoniae and subsequently infected with respiratory syncytial virus (RSV), type 2 human adenovirus or influenza B. Levels of pro-inflammatory cytokines, viral replication and expression of pattern recognition receptors were determined in culture supernatants and/or cell lysates. (biomedcentral.com)
  • The most familiar and predominant form is H. influenzae type b (Hib), which infects mostly children and immunocompromised individuals. (statpearls.com)
  • Type f strain also increasingly recognized as a cause of severe infection, though less common than Hia. (hopkinsguides.com)
  • What is Haemophilus Influenza Type B (HIB)? (nvic.org)
  • H. influenzae type b (Hib) is transmitted by direct contact with respiratory secretions and enters the body through the upper respiratory tract. (nvic.org)
  • A diagnosis of H. influenzae , including H. influenzae type b, is made by the laboratory testing of bodily fluids such as blood and spinal fluid. (nvic.org)
  • Oral lactoferrin prevents body weight loss and increases cytokine responses during herpes simplex virus type 1 infection of mice. (microbiologyresearch.org)
  • Sinusitis Sinusitis is inflammation of the paranasal sinuses due to viral, bacterial, or fungal infections or allergic reactions. (msdmanuals.com)
  • These superstars of the diet world are normally broken down to form molecules that help turn off inflammation after an infection or injury. (futurity.org)
  • Some of H. influenzae have a polysaccharide capsule depending upon which they are classified into 6 distinct groups designated as serotypes a, b, c, d, e, and f. (statpearls.com)
  • Nontypeable H. influenzae now cause the majority of invasive H. influenzae disease in all age groups. (cdc.gov)
  • The mother may be febrile or have other signs of infection, depending on the integrity of her host defenses, the responsible organism, and other considerations. (medscape.com)
  • For microbiologic aspects of the causative organism(s), see Haemophilus influenzae . (wikidoc.org)
  • The organism appears to spread contiguously from its colonizing position in the respiratory tract to the infection site. (msdmanuals.com)
  • The other capsular types are less common causes of infection. (statpearls.com)
  • Our group is interested in the research of clinically relevant bacterial species that mainly cause upper and lower airway infections and their interactions with the host. (lu.se)
  • H. influenzae is the most notable species, but a notable decline in past decades has been achieved due to active childhood immunization ( Hib ). (hopkinsguides.com)
  • The virus infections spread readily within the team, most commonly within the same sport discipline. (bmj.com)
  • Epidemiological studies suggest that inhalation of toxins increases the risk of airway bacterial infection. (ersjournals.com)
  • If the mother has a bloodstream infection, the microorganism can readily cross the few cell layers that separate the maternal from the fetal circulation at the villous pools of the placenta. (medscape.com)
  • However, the likelihood of hematogenous transmission is increased if the mother has continuous bloodstream infection with a relatively large quantity of microorganisms. (medscape.com)
  • These infections can range from mild ear infections to severe diseases, like bloodstream infections. (wikidoc.org)
  • We report the transmission dynamics of MRSA among hospitalized patients with bloodstream infections. (robertpetit.com)
  • The incubation period (time between exposure and first symptoms) of H. influenzae disease is not certain but could be as short as 7 days. (wikidoc.org)
  • Acute bronchitis can be defined as acute bacterial or viral infection of the larger airways in healthy patients with no history of recurrent disease. (bionity.com)
  • Disease caused by H. influenzae can affect many organ systems. (cdc.gov)
  • People ≥65 years of age with invasive H. influenzae disease (Hib, non-b, and nontypeable) have higher case-fatality ratios than children. (cdc.gov)
  • See the H. influenzae surveillance page for information on disease trends since 1999. (cdc.gov)
  • For guidelines on treatment and chemoprophylaxis for invasive Hib disease, see the H. influenzae chapter of the Red Book external icon . (cdc.gov)
  • CDC recommends chemoprophylaxis for close contacts of Hib cases, but does not have guidelines for other types of H. influenzae disease. (cdc.gov)
  • Death rates from H. influenzae disease were also found to be significantly higher among seniors over age 65, with 67 percent of infections resulting in death. (nvic.org)
  • BackgroundIndividuals with sarcoidosis are at higher risk for infection owing to underlying disease pathogenesis and need for immunosuppressive treatment. (journaltocs.ac.uk)
  • One such lipoprotein, OmpP4, is homologous to the outer membrane lipoprotein e (P4) of H. influenzae . (biomedcentral.com)
  • Infection of amniotic fluid often involves ascending pathogens from the birth canal but may result from hematogenous seeding or direct introduction during pelvic examination, amniocentesis, placement of intrauterine catheters, or other invasive procedures. (medscape.com)
  • Appropriate clearance of pathogens and response to pollutants is required to prevent overwhelming infection, while preventing tissue damage and maintaining efficient gas exchange. (biomedcentral.com)