• Non-aspirin NSAIDs are licensed for the relief of pain and inflammation arising from rheumatic disease. (bris.ac.uk)
  • OBJECTIVES: To determine whether there is a difference in the relative efficacy of individual non-steroidal anti-inflammatory drugs (NSAIDs) when used in the management of osteoarthritis (OA) of the knee. (bris.ac.uk)
  • The MeSH heading "osteoarthritis" was combined with the generic names of the 17 non-aspirin NSAIDs licensed in the UK for the management of OA in general practice. (bris.ac.uk)
  • The search of Embase used the term "osteoarthritis" if present in the abstract, title or keywords, and was combined with the generic names of the 17 non-aspirin NSAIDs, only if they were mentioned in the title, abstract or keywords. (bris.ac.uk)
  • SELECTION CRITERIA: All double blind, randomised controlled trials, in the English language, comparing the efficacy of two non-aspirin NSAIDs in the management of osteoarthritis of the knee, were selected. (bris.ac.uk)
  • Studies which compared one "trial" NSAID with one "reference" NSAID were included provided they were non-aspirin NSAIDs available in the UK and were licensed for the treatment of OA by general practitioners. (bris.ac.uk)
  • Aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs) are used for osteoid osteoma. (medscape.com)
  • If the laboratory data support the clinical diagnosis, symptomatic treatment with aspirin or non-steroidal anti-inflammatory drugs (NSAIDs) with gastroprotection should be initiated. (escardio.org)
  • Colchicine is recommended first-line therapy as an adjunct to aspirin/NSAIDs. (escardio.org)
  • Low-dose corticosteroids should be considered in cases of contraindications/failure of aspirin/NSAIDs and colchicine, and when an infectious cause has been excluded, or when there is a specific indication such as autoimmune disease. (escardio.org)
  • The major risk factors associated with poor prognosis in acute pericarditis include high fever, subacute course, evidence of large pericardial effusion, cardiac tamponade and failure to respond within seven days to non-steroidal anti-inflammatory drugs (NSAIDs). (escardio.org)
  • An example of acute gastritis is stomach upset that may follow the use of alcohol or certain medications such as aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs). (emedicinehealth.com)
  • The Cox1/2 inhibitors are included in the umbrella term non-steroidal anti-inflammatory drugs (NSAIDs) In addition to these drugs, cortisone-based steroids could be candidates to address inflammaging, although they have, in addition to their anti-inflammatory effects also immune-suppressive activities. (springer.com)
  • On the other hand, a systematic review concluded that there was no evidence for clinical benefits from the use of NSAIDs or steroidal drugs in the treatment of patients with dementia [ 11 ]. (springer.com)
  • non-steroidal anti-inflammatories (NSAIDs) such as aspirin - to reduce pain and inflammation. (heartfoundation.org.nz)
  • Examples are acetaminophen and nonsteroidal anti-inflammatory drugs (NSAIDs), like aspirin and ibuprofen. (mdanderson.org)
  • The most common treatment for menstrual pain is the use of nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen and aspirin. (alive.com)
  • Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) are helpful to reduce inflammation and sciatic nerve pain. (indiasurgerytour.com)
  • NSAIDs include aspirin and ibuprofen. (indiasurgerytour.com)
  • Januvia may also interact with digoxin , probenecid, nonsteroidal anti-inflammatory drugs ( NSAIDs ), aspirin or other salicylates, sulfa drugs, monoamine oxidase inhibitors (MAOIs), or beta-blockers. (rxlist.com)
  • As such, don't use aspirin if you're allergic to other NSAIDs, such as ibuprofen and naproxen . (healthline.com)
  • Treatment includes supportive care of symptoms, but the use of aspirin and non-steroidal anti-inflammatory drugs (NSAIDs) must be avoided since they increase the risk of bleeding. (iamat.org)
  • These drugs are all called nonsteroidal anti-inflammatory drugs (NSAIDs). (health.am)
  • Acetaminophen is the drug of choice for patients who have a documented hypersensitivity to aspirin or NSAIDs, who have a history of upper gastrointestinal (GI) tract disease, or who are on anticoagulants. (medscape.com)
  • NSAIDs have analgesic, anti-inflammatory, and antipyretic activities. (medscape.com)
  • For patients with high GI risk and high cardiovascular risks requiring concomitant aspirin and NSAIDs, the guidelines are very conflicting. (medscape.com)
  • The study enrolled 514 H. pylori-negative patients who presented with upper GI bleeding, were on NSAIDs and required concomitant aspirin. (medscape.com)
  • NSAIDs are a group of chemically dissimilar agents, other than steroids, commonly used to treat a variety of conditions because of their analgesic, anti-inflammatory, and antipyretic properties. (cdc.gov)
  • Take a nonsteroidal anti-inflammatory drug (NSAID). (medlineplus.gov)
  • Aspirin is the most widely prescribed nonsteroidal anti-inflammatory drug (NSAID) worldwide. (hindawi.com)
  • Other common ulcer risks include smoking cigarettes, drinking a lot of alcohol, or regularly using NSAID pain relievers like aspirin and ibuprofen. (mountsinai.org)
  • Growing evidence over the past decade suggests that people who take a regular dose of aspirin or other non-steroidal anti-inflammatory drug (NSAID) are significantly less susceptible to colorectal cancer , breast cancer and a number of other malignancies . (ucsf.edu)
  • The mainstay of treatment is non-steroidal anti-inflammatory (NSAID) medication- i.e. (rxmed.com)
  • Aspirin is a nonsteroidal anti-inflammatory drug ( NSAID ). (healthline.com)
  • This includes aspirin, any other type of non-steroidal anti-inflammatory drug (NSAID) , or vitamin E. (alberta.ca)
  • Colchicine combined with non-steroidal anti-inflammatory drug (NSAID) or acetylsalicylic acid (aspirin) were prescribed to 39/54 (72%) patients. (bvsalud.org)
  • NEW YORK (Reuters Health) - For patients with a history of upper GI bleeding while taking a non-steroidal anti-inflammatory drug (NSAID) and aspirin who need to continue both drugs, celecoxib with a proton-pump inhibitor (PPI) is "the preferred treatment" to reduce the risk of recurrent GI bleeding, researchers advise based on results of the CONCERN study. (medscape.com)
  • The CONCERN study tested whether the COX-2 selective NSAID celecoxib plus a PPI is superior to the non-selective NSAID naproxen plus a PPI for prevention of recurrent ulcer bleeding in concomitant users of aspirin with previous GI bleeding. (medscape.com)
  • WITHDRAWN: Non-aspirin, non-steroidal anti-inflammatory drugs for treating osteoarthritis of the knee. (bris.ac.uk)
  • you are allergic to a family of drugs known as salicylates (which include aspirin). (mydr.com.au)
  • A previously unidentifiable type of low-grade inflammation may explain why common anti-inflammatory drugs such as aspirin have shown promise against some types of cancer - even when patients don't display typical signs of inflammation. (ucsf.edu)
  • Targets for potential anti-inflammatory drugs are, among others, the pathways of the classical lipid-mediators of inflammation. (springer.com)
  • The medication segmented is sub segmented into analgesics and non-steroidal anti-inflammatory drugs, and others. (medgadget.com)
  • The non-steroidal anti-inflammatory drugs sub segment, by medication, is further segmented into aspirin, ibuprofen, naproxen sodium and naproxen, and others. (medgadget.com)
  • Non-steroidal anti-inflammatory drugs like ibuprofen and aspirin should be avoided as they can increase the risk of bleeding. (globalissues.org)
  • Drugs like ibuprofen, aspirin, and naproxen reduce pain and swelling. (aaos.org)
  • If you've been diagnosed with psoriatic arthritis, your physician may give you aspirin, ibuprofen or prescription drugs. (health.am)
  • Treatment of Pain Nonopioid and opioid analgesics are the main drugs used to treat pain. (msdmanuals.com)
  • Aspirin and other nonsteroidal anti-inflammatory drugs, non-steroidal should be avoided until dengue can be discarded to reduce the risk of hemorrhage.When traveling to countries where the Zika virus or other viruses transmitted by mosquitoes have been reported, the recommendation is to use insect repellent, long sleeves and pants, and stay in places with air conditioning or window and door fitted with insect screens. (bvsalud.org)
  • One of the effective strategies currently used in these cases is structured to evaluate the painful condition through a 3-D approach which establish a differential diagnosis, definitive treatment, and rational use of drugs, based on the most appropriate scientific evidence available in the literature. (bvsalud.org)
  • The effective strategy for managing the endodontic pain is based in the pain assessment through a 3-D approach that consists of establishing the differential diagnosis, definitive treatment, and rational use of drugs 13 . (bvsalud.org)
  • Regular use of aspirin and other non-steroidal anti-inflammatory drugs and breast cancer risk for women at familial or genetic risk: a cohort study. (cdc.gov)
  • Medication history is important because discontinuation of anti-inflammatory medications often precipitates a reaction. (medscape.com)
  • Your care team may recommend non-drug treatments for managing your cancer pain in addition to your pain medication. (mdanderson.org)
  • These treatments may help your medicines work better and relieve other symptoms, but they should not be used instead of medication. (mdanderson.org)
  • Chronic sciatica may require a muscle relaxant and/or anti-depressant medication. (indiasurgerytour.com)
  • We begin with nonsurgical approaches, such as oral anti-inflammatory medications, ice and heat application, and physical therapy. (ucsfhealth.org)
  • Medical treatment for gastritis include medications to decrease the acid in the stomach and antibiotics against the organism causing gastritis. (emedicinehealth.com)
  • Certain anti-seizure and anti-depressant medications are effective in blocking pain messages sent to the brain. (indiasurgerytour.com)
  • Both Januvia and Onglyza may interact with other anti-diabetic medications. (rxlist.com)
  • Although Januvia by itself usually does not cause low blood sugar ( hypoglycemia ), low blood sugar may occur if Januvia is prescribed with other anti-diabetic medications. (rxlist.com)
  • Low blood sugar may occur if this drug is prescribed with other anti-diabetes medications. (rxlist.com)
  • People can react differently to different medications, so it can be normal to try a number of treatment options to see what works for you. (ra.com)
  • Thus, medications with a combination of analgesic and anti-inflammatory properties become more desirable, at least in theory. (medscape.com)
  • The real-world insights from XALIA confirm the positive benefit-risk profile of rivaroxaban for the treatment of deep vein thrombosis that was observed in the Phase 3 EINSTEIN-DVT study, signalling that the medicine is performing as expected in patients that physicians typically see in everyday clinical practice. (jnj.com)
  • XALIA - which included approximately 5,000 patients from 21 countries 1 - evaluated the safety and effectiveness of XARELTO ® , taken once daily, for the treatment of DVT in routine clinical practice as compared to standard anticoagulation. (jnj.com)
  • Patients without signs and symptoms of systemic inflammatory disease can be managed as outpatients with empiric anti-inflammatories and short-term follow-up after one week to assess the response to treatment. (escardio.org)
  • Prophylaxis and chronic treatment of asthma in patients 2 years of age and older ( 1.1 ). (nih.gov)
  • Patients with known aspirin sensitivity should continue to avoid aspirin or non-steroidal anti-inflammatory agents while taking montelukast sodium ( 5.3 ). (nih.gov)
  • Susvimo (ranibizumab injection) is a vascular endothelial growth factor (VEGF) inhibitor indicated for the treatment of patients with Neovascular (wet) Age-related Macular Degeneration (AMD) who have previously responded to at least two intravitreal injections of a VEGF inhibitor. (rxlist.com)
  • For dying patients, comfort measures, including nonspecific treatment or a short sequential trial of empiric treatments, often serve patients better than an exhaustive diagnostic evaluation. (msdmanuals.com)
  • Patients and physicians must recognize that all pain can be relieved by an appropriately potent drug at sufficient dosage, although aggressive treatment may also cause sedation or confusion. (msdmanuals.com)
  • However, patients stable on low dose aspirin (upto 300mg/day) for at least 3 month prior to enrolment will be eligible. (who.int)
  • All patients resumed aspirin 80 mg once daily. (medscape.com)
  • Twenty-one (8%) patients in the celecoxib group and 17 (7%) in the naproxen group had adverse events leading to discontinuation of treatment. (medscape.com)
  • Our findings have shown that among these high risk patients, naproxen plus aspirin should be avoided despite co-therapy with a PPI. (medscape.com)
  • Home treatment does not relieve the symptoms. (medlineplus.gov)
  • A variety of treatments exist to remove fibroids and relieve symptoms. (healthywomen.org)
  • If you learn you have fibroids but aren't experiencing symptoms, you usually won't need treatment. (healthywomen.org)
  • If you're experiencing symptoms despite being on treatment, you should bring it up. (ra.com)
  • It concluded that topical aspirin helped reduce some symptoms, but not the accompanying itch. (healthline.com)
  • If symptoms start to get worse 1 to 3 days after the treatment, call your doctor. (alberta.ca)
  • The treatment of symptoms can include rest, fluid intake, antipyretics and analgesics. (bvsalud.org)
  • Notwithstanding, most of the pain symptoms is related to the alterations in the pulp and periapical tissue, and endodontic treatment is generally indicated 24 . (bvsalud.org)
  • As a precaution, avoid using any form of aspirin during pregnancy and breastfeeding , unless your doctor tells you to for certain medical conditions . (healthline.com)
  • This relationship is mysterious, because most of the cancers that aspirin appears to prevent typically show no overt signs of inflammation. (ucsf.edu)
  • Topical or intralesional corticosteroids are most commonly used for treatment of LSC. (jcadonline.com)
  • Treatment with non-steroidal anti-inflammatory and colchicine is usually effective but corticosteroids are sometimes required. (bvsalud.org)
  • Bone Tumors: Diagnosis, Treatment and Prognosis. (medscape.com)
  • Find out what causes pericarditis and learn about its diagnosis and treatment. (heartfoundation.org.nz)
  • The Global Osteoarthritis Market is segmented on the basis of type, diagnosis, treatment, and end users. (medgadget.com)
  • From diagnosis to treatment, our experts provide the care and support you need, when you need it. (mskcc.org)
  • The emergency cases resulting from orofacial pain require immediate attention of the dentist, and the clinician must be apt to identify the evolution, analyze the clinical features, and establish the differential diagnosis and treatment planning capable of relieving the patient's pain 20 . (bvsalud.org)
  • If the pain continues after 6 to 12 months of rest and treatment, surgery may be recommended. (medlineplus.gov)
  • Surgical treatment generally works well to reduce pain and restore range of motion. (ucsfhealth.org)
  • Since each patient's cancer pain is unique, treatment plans for pain management should be tailored the individual's needs. (mdanderson.org)
  • It is important to have your pain evaluated so your care team can provide the best methods for treatment. (mdanderson.org)
  • You should call your doctor if your heel pain does not get better after two or three weeks of home treatment. (mountsinai.org)
  • Your treatment will depend on the cause of your heel pain. (mountsinai.org)
  • Keeping in mind that each person is unique in terms of underlying cause, most often menstrual pain can be due to stagnation of qi or blood in the body, so the goal of treatment is to relieve stagnation and promote their smooth flow. (alive.com)
  • Acupuncture treatments involve inserting small needles into the skin at certain points, known as energy meridians, in order to relieve pain. (alive.com)
  • Acute or chronic sciatic nerve pain may require more aggressive types of non-surgical treatment. (indiasurgerytour.com)
  • If pain persists, it is important to seek proper medical treatment. (aaos.org)
  • The primary treatment of Sever's disease is to rest the foot (stop the sport) until the pain goes away. (aaos.org)
  • Can have initial anti-inflammatory effects, and can inhibit pain transmitters in the brain. (pulled-muscle.com)
  • You might primarily know of aspirin as a pain reliever. (healthline.com)
  • The goals of treatment include pain alleviation and improvement of functional status. (medscape.com)
  • Unfortunately, he developed chest pain eight months after the treatment initiation. (bvsalud.org)
  • We then stopped the stimulant and changed his treatment to atomoxetine, after which he no longer had chest pain. (bvsalud.org)
  • Instead, a combination of celecoxib, aspirin and PPI is the preferred treatment if pain cannot be relieved by simple analgesics," said Dr. Chan and Dr. Kyaw. (medscape.com)
  • Pain management in endodontics includes important aspects for its control and prevention, such as reducing anxiety and preoperative pain, control of intra-operative pain and the treatment of postoperative pain. (bvsalud.org)
  • This is despite scientific advances in improving treatment outcomes and understanding the pathogenesis [IOM 2000]. (cdc.gov)
  • MESALAZINE 1.2 TAKEDA is an anti-inflammatory drug used for the treatment of ulcerative colitis. (mydr.com.au)
  • on the right, parainflammation nearly disappears from the tumor after treatment with a non-steroidal anti-inflammatory drug similar to aspirin. (ucsf.edu)
  • Treatment within the previous 3 months with any drug known to have a well defined potential for hepatotoxicity. (who.int)
  • Anti-inflammatory and analgesic effects of homeopathic remedies based on Bryonia were demonstrated in animal studies [28] . (researchgate.net)
  • Diclofenac is one of a series of phenylacetic acids that have demonstrated anti-inflammatory and analgesic properties in pharmacologic studies. (medscape.com)
  • Bacteriostatic, immune modulating, anti-inflammatory and analgetic effects of homeopathic mono-preparations Aconitum D4, Phytolacca D1, Bryonia D and D4, Lachesis D8, Mercurius solubilis D4 were investigated in a study on fifty cows with acute mastitis. (researchgate.net)
  • You may have also read about various home remedies that some may use for acne treatment, one of which is topical aspirin . (healthline.com)
  • There's currently no evidence of anti-inflammatory benefits from using topical aspirin for acne. (healthline.com)
  • Topical aspirin isn't recommended as a form of acne treatment. (healthline.com)
  • The most common side effects of using topical aspirin are skin dryness and irritation. (healthline.com)
  • You may also be more prone to these effects if you apply topical aspirin often. (healthline.com)
  • If your psoriasis is mild or moderate, your physician probably will give you topical treatments first. (health.am)
  • Topical treatments are ointments, gels or lotions that may contain steroids or coal tar. (health.am)
  • Objectives: The study objective was to evaluate the effectiveness of homeopathic medicines for the prevention and treatment of migraine in children. (researchgate.net)
  • Preventive treatment during this time consisted of homeopathic medicines in 98% of cases (mean=2.6 medicines/patient). (researchgate.net)
  • Conclusions: The results of this study demonstrate the interest of homeopathic medicines for the prevention and treatment of migraine attacks in children. (researchgate.net)
  • Learn about a treatment option for moderate to severe RA and talk to your rheumatologist to see if it could be right for you. (ra.com)
  • It is a common, safe and very effective treatment for moderate to severe psoriasis. (health.am)
  • To avoid irritating an ulcer a person can try eliminating certain substances from their diet such as caffeine, alcohol, aspirin, and avoid smoking. (mountsinai.org)
  • Treatment depends on the clinical picture, the experience of the treating physician, and the availability of ancillary services. (medscape.com)
  • As part of our mission to eliminate cancer, MD Anderson researchers conduct hundreds of clinical trials to test new treatments for both common and rare cancers. (mdanderson.org)
  • It's a well-known treatment for mild acne, although the American Academy of Dermatology (AAD) notes that clinical trials demonstrating its effectiveness are limited. (healthline.com)
  • Because one symptom can have many causes and may respond differently to treatment as the patient's condition deteriorates, the clinical team must monitor and reevaluate the situation frequently. (msdmanuals.com)
  • This is why more and more women are looking for safe and effective natural treatments to help relieve painful periods. (alive.com)
  • Early treatment for psoriatic arthritis, for example, can prevent your joints from becoming more painful. (health.am)
  • They are also used for treatment of headaches, fever, dental and other common painful conditions. (cdc.gov)
  • The incidence of small intestinal injury caused by low-dose aspirin (LDA) is high, but the pathogenesis and intervention measures of it have not been elucidated. (hindawi.com)
  • Low-dose aspirin (LDA) is widely used in the primary and secondary prevention and treatment of cardiovascular and cerebrovascular diseases. (hindawi.com)
  • If you are taking the highest daily dose of 4.8g/day, you should be evaluated after 8 weeks of treatment. (mydr.com.au)
  • Females of reproductive potential should use effective contraception during treatment with Susvimo and for at least 12 months after the last dose of Susvimo. (rxlist.com)
  • The FDA approved a submicron low-dose product (Zorvolex) for osteoarthritis that allows treatment at a lower dose than the diclofenac sodium and potassium salts. (medscape.com)
  • Treatment of inverse psoriasis can be difficult and requires a different approach to the more common cutaneous forms of the disease due to the sensitivity of skin in the susceptible areas. (jcadonline.com)
  • Any acne treatments you put on your face, including aspirin, can increase your skin's sensitivity to the sun's ultraviolet (UV) rays. (healthline.com)
  • Your doctor may change your diabetes treatment during pregnancy. (rxlist.com)
  • Simple analgesics are now accepted as the appropriate first line pharmacological treatment of uncomplicated OA. (bris.ac.uk)
  • In the early to mid-1980s, histamine 2 (H2)-receptor antagonists were the most commonly prescribed agents for treatment of GERD. (medscape.com)
  • Consequently, anti-inflammatory interventions have been proposed for treatment and/or prevention of age-related diseases [ 8 ]. (springer.com)
  • Therefore, it is necessary to further investigate the potential mechanism of LDA-related small intestinal injury to promote the prevention and treatment of this type of injury. (hindawi.com)
  • For more advice on COVID-19 prevention and treatment, visit our coronavirus hub . (medicalnewstoday.com)
  • The aim of another study was to assess the efficacy of homeopathic remedies for the prevention and treatment of migraine in children [28] . (researchgate.net)
  • The results of this study showed the efficacy of homeopathic preparations for the prevention and treatment of migraine attacks in children [28] . (researchgate.net)
  • Evaluate the risks and benefits of continuing treatment with montelukast sodium if such events occur ( 5.4 and 6.2 ). (nih.gov)
  • Prompt treatment is important to prevent gout from turning chronic. (healthline.com)
  • We sought to evaluate the efficacy and safety of intradermal injection of botulinum toxin A in the treatment of localized recalcitrant chronic pruritus in lichen simplex, inverse psoriasis, post-burn itching, lichen planus (hypertrophic), and postherpetic neuralgia. (jcadonline.com)
  • Although an effective treatment approach is to stop taking aspirin, aspirin withdrawal greatly increases the risks of cardiovascular and cerebrovascular complications and mortality. (hindawi.com)
  • While there is no cure, many different treatments can clear psoriasis for periods of time. (health.am)
  • On average, every 37 seconds someone in the Western world dies from a venous blood clot, so it is important we understand the effectiveness and safety of available treatment options for these potentially life-threatening blood clots," said XALIA principal investigator Professor Alexander G. G. Turpie, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada. (jnj.com)
  • In line with this idea, montelukast treatment restored learning and memory in aged rats, involving a reduction in neuroinflammation, but also a re-activation of neurogenesis as well as a restoration of the blood-brain-barrier integrity [ 14 ]. (springer.com)
  • Effect of genetic polymorphisms on Alzheimer's disease treatment outcomes: an update. (cdc.gov)
  • Whenever possible, complete surgical excision is the treatment of choice for primary tumors (except multiple myeloma). (medscape.com)
  • Octagam is an immune globulin intravenous (human), 5% liquid, indicated for treatment of primary humoral immunodeficiency (PI) (1). (nih.gov)
  • Non-steroidal anti-inflammatories are another common method of recovery. (pulled-muscle.com)
  • While there is currently no specific treatment for dengue, early detection and appropriate healthcare for case management can significantly reduce mortality. (globalissues.org)
  • The treatment plan your doctor recommends will depend on the stage and severity of your gout. (healthline.com)
  • The AAD recommends taking aspirin orally to reduce skin swelling related to conditions like sunburn . (healthline.com)
  • As with the treatment of any disorder, a carefully taken patient history and a carefully made physical examination are of paramount importance. (medscape.com)
  • The Johns Hopkins Sinus Center provides state-of-the-art evaluation and treatment for a variety of nose and sinus conditions, including environmental allergies, nasal obstruction, nasal tumor and related disorders. (hopkinsmedicine.org)
  • As with other arthritic conditions, initial treatment of shoulder arthritis is usually nonsurgical. (ucsfhealth.org)
  • Botulinum toxin has also been used experimentally in the treatment of many other dermatological conditions with positive results, including persistent facial flushing, gustatory sweating, anal fissures, familial benign pemphigus, dyshidrotic eczema, and surgical wound closures. (jcadonline.com)
  • It's important to talk to your doctor or dermatologist before applying aspirin on your acne - especially if you're using other types of topicals or if you have any underlying health conditions. (healthline.com)