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  • drug
  • Oocytes were cultured in the presence of 10 μg/ml nocodazole from 3 to 5 h after GVBD and fixed 2 h after removal of the drug (A). Oocytes were cultured in the presence of 10 μg/ml nocodazole from 6 to 8 h after GVBD and fixed 15 (B) and 30 min (C) after removal of the drug. (nih.gov)
  • model
  • Nocodazole reversibly inhibited 20-30% of the tubular accumulation of two model organic anions, p-aminohippurate and fluorescein (FL), by winter flounder tubular masses. (mysciencework.com)
  • To confirm the feasibility of using this model, we treated labeled zebrafish with nocodazole and demonstrated that it could disrupt mitochondrial transport. (frontiersin.org)
  • cells
  • Incubation with the endocytic trafficking blocker, nocodazole, led to an increase in hERG activity at 37 degrees C, but not at 30 degrees C. CONCLUSION: Our results are consistent with the concept that maintenance of cells at reduced temperature can be used to boost the functional expression of difficult-to-express membrane proteins and improve the quality of assays for medium to high-throughput compound screening. (epfl.ch)