Concentrated H2SO4 is such a strong acid, that it will protonate any compound containing a heteroatom with lone pair e- along with alkenes and alkynes. (studylib.net)
Cyclopropanation of Alkenes2
During this work, we investigated the synthesis of these units in enantioenriched form via the Rh(II)-catalyzed cyclopropanation of alkenes using di-acceptor diazo compounds as substrates. (umontreal.ca)
Following the initial development of a method for the catalytic asymmetric cyclopropanation of alkenes using nitro diazoketones, many experimental studies on the mechanism of stereoinduction in this reaction were performed. (umontreal.ca)
Compounds2
An operationally simple and entirely green protocol for heteropoly acid catalyst conjugate addition of indoles and pyrrole to unsaturated carbonyl compounds and nitro-alkene in water was investigated. (sharif.edu)
The nitronate anion can react under basic conditions with saturated carbonyl compounds or with electron poor alkenes leading to the nitroaldol (Henry) reaction or to the Michael reaction, respectively, with the formation of di- or polyfunctionalized nitroderivatives. (designer-drug.com)
Derivatives1
ii, for the Michael reaction) low yields, the efficiency with a restricted class of electrophilic olefins, the need of ultrasound, and/or the demand of a large excess of nitro compound that, for valuable nitro derivatives, is a serious economic drawback. (designer-drug.com)
Alkanes1
The volatile hydrocarbon fraction of gasoline, which consists primarily of short-chain (C4-C5) alkanes and alkenes and some aromatics, partitions to the atmosphere where photochemical oxidation is the main removal process. (cdc.gov)
Ketones1
this seems not to be a problem since the main uses are the conversion into alfa-nitro ketones 2,3,5,16 or conjugated nitroalkenes, 5,17 in which at least one stereogenic centre is lost. (designer-drug.com)
Amino2
While nitro and amino alkenes are common in pharmaceuticals, pesticides, and munitions, their environmental fates are not well known. (bvsalud.org)
Vinyl nitro groups substantially decrease the reactivity, while amino groups have the opposite effect. (bvsalud.org)
Reaction5
A nitroalkene, or nitro olefin, is a functional group combining the functionality of its constituent parts, an alkene and nitro group, while displaying its own chemical properties through alkene activation, making the functional group useful in specialty reactions such as the Michael reaction or Diels-Alder additions. (wikipedia.org)
reaction: see text] A novel binaphthyl-derived amine thiourea organocatalyst has been developed and demonstrated to efficiently catalyze Michael addition reactions (using as low as 1 mol % loading) of diketones to nitroalkenes with remarkably high enantioselectivities. (unboundmedicine.com)
In connection with our interest in the application of heterogeneous catalysis for fine chemicals preparation 13 with particular interest in the organicinorganic hybrid materials, 14 we planned to find a new heterogeneous catalyst able to promote both (i) the Henry reaction and (ii) the Michael reaction of nitroalkanes to electron-poor alkenes under solventless conditions. (designer-drug.com)
it should be noted that the very mild reaction conditions prevent typical side reactions such as the retro-aldol reaction 5,6 or the dehydration of the 2-nitro alcohol into nitroalkene. (designer-drug.com)
Several 2-nitroalkyl polysaccharide ethers (from pullulan (1), guar (2), agarose (3), inulin (4), cellulose (5), Na-α-polyglucuronate (6) and hydroxyethyl cellulose (7)) were synthesized by reaction with 2-nitro-1-alkenes (2-nitro-1-propene and 2-nitro-1-butene) formed in situ from 2-nitroalkyl acetates. (tno.nl)
Reactions2
Ozone is a ubiquitous atmospheric oxidant for alkenes, but the synergistic effects of nitrogen-containing groups on the reactions have not been measured. (bvsalud.org)
H O H2SO4 + H C R O + C R R water insoluble R water soluble In other cases, such as alkenes, protonation leads to reactions that produce the brown color that is often observed. (studylib.net)
Michael1
N or S mustards, Michael reactive acceptors, and halo alkenes primary halides. (smitherspira.com)
Poor1
By contrast, the α, β-disubstituted nitroalkene, (E) -2-nitro-1-phenylpropene, was reduced with a moderate yield of 56 % and poor enantioselectivity (16 % ee for (S) -2-nitro-1-phenylpropane). (microbiologyresearch.org)
Hydrocarbons1
The physical state depends on molecular mass: like the corresponding saturated hydrocarbons, the simplest alkenes, ethene, propene, and butene are gases at room temperature. (everipedia.org)
Synthesis3
Practical synthesis of allylic amines via nickle-catalysed multicomponent coupling of alkenes, aldehydes, and amides. (nankai.edu.cn)
Synthesis of Tricyclic [1,2-α]Indoles via Nickle-Catalyzed Intramolecular Imine-Alkene Coupling. (nankai.edu.cn)
298] Stereoselective Alkylation of Chiral Nitro Imine and Nitro Hydrazone Dianions, Synthesis of Enantiomerically Enriched 3-Substituted 1-Nitrocyclohexenes (with J. J. Ares) J. Org Chem , 2008 , 73 , 9647-9656. (illinois.edu)
Alkylation1
Stereoselective Alkylation of Chiral alpha-Nitro Ketoimine Dianions. (illinois.edu)
Olefin2
A nitroalkene, or nitro olefin, is a functional group combining the functionality of its constituent parts, an alkene and nitro group, while displaying its own chemical properties through alkene activation, making the functional group useful in specialty reactions such as the Michael reaction or Diels-Alder additions. (wikipedia.org)
[1] The words alkene and olefin are often used interchangeably (see nomenclature section below). (everipedia.org)
Carbon -car1
In organic chemistry, an alkene is an unsaturated hydrocarbon that contains at least one carbon -carbon double bond. (everipedia.org)
Metathesis1
Finally, artificial metalloenzymes based on the streptavidin-biotin system have now been applied to asymmetric imine reduction, dihydroxylation and alkene metathesis. (york.ac.uk)
Imine1
alpha-Nitro Keto Hydrazone and Keto Imine Dianions. (illinois.edu)
Isomers2
As a consequence, substituted alkenes may exist as one of two isomers, called cis or trans isomers. (everipedia.org)
In this reaction two alkenes and are treated with a transition metal that acts as a catalyst, giving a mixture of alkenes (including Z/E isomers). (quimicaorganica.org)
Organic1
The simplest alkene, ethylene (C2H4), with the International Union of Pure and Applied Chemistry (IUPAC) name ethene , is the organic compound produced on the largest scale industrially. (everipedia.org)
Asymmetric2
Recent Advances in Nickle-Catalyzed Asymmetric Hydrofunctionalization of Alkenes. (nankai.edu.cn)
In reductase biotransformations, ene reductases of the Old Yellow Enzyme family have been applied to the asymmetric reduction of Baylis-Hillman adducts and also shown, in some cases, to catalyse oxazete formation in the transformation of nitro-alkenes. (york.ac.uk)
Acid3
Fatty acid nitroalkenes inhibit the inflammatory response to bleomycin-mediated lung injury. (nih.gov)
Fatty acid nitroalkenes are reversibly-reactive electrophiles, endogenously detectable at nM concentrations, displaying anti-inflammatory actions. (nih.gov)
Nitroalkenes like 9- or 10-nitro-octadec-9-enoic acid (e.g. nitro-oleic acid, OA-NO2) pleiotropically suppress cardiovascular inflammatory responses, with pulmonary responses less well defined. (nih.gov)
Transition1
As seen above, the endo transition state leads to the nitro group being opposite the CH 2 bridge - for more information about endo and exo see this page . (chemtube3d.com)
Occur1
For bridged alkenes, Bredt's rule states that a double bond cannot occur at the bridgehead of a bridged ring system unless the rings are large enough. (everipedia.org)
Complex1
More complex alkenes may be named with the E - Z notation for molecules with three or four different substituents (side groups). (everipedia.org)