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Outbreak of Nipah virusKeralaIndiaSungai Nipah2018Fruit batsBatsHenipavirusCases of Nipah virus1998Centers for Diseas1999MalaysiaInfection with Nipah virusGlycoproteinAnti-Nipah virusPigsDeadlyPteropusAntibodiesCase of Nipah virusSymptoms of Nipah virusTreatment for Nipah virusKozhikodeSupportive careDiseaseParamyxoviridaeVaccinesPathogenGenusFlying foxesPathogens2019ParamyxovirusDiscovered in Australia in 1994People infected with Nipah virusSpread of the Nipah virusVirologyRecombinantEpidemicDiseasesSource of Nipah virusVaccine for Nipah virusPresence of Nipah virusSevereIsolationMeaslesInflammation of the brainPreventionMonoclonalInfectsDiagnosisNeurological
Outbreak of Nipah virus12
Kerala50
  • International SOS is currently monitoring the situation in Kerala closely, following the confirmation of a Nipah virus case. (internationalsos.com)
  • Nipah virus has so far claimed 10 lives in Kozhikode and Malappuram districts in north Kerala while the condition of two undergoing treatment is said to be critical. (indiatimes.com)
  • A year after two north Kerala districts were hit by Nipah claiming 17 lives, the disease resurfaced in the state with a 23-year-old student here confirmed to be infected with the potentially deadly virus. (sify.com)
  • Earlier, blood samples examined at two virology institutes--Manipal Institute of Virology and Kerala Institute of Virology and Infectious Diseases--had indicated Nipah. (sify.com)
  • NEW DELHI (Reuters) - The deadly brain-damaging Nipah virus has resurfaced in Kerala a year after it killed 17 people, state officials said on Tuesday. (reuters.com)
  • Kerala Health Minister K.K. Shailaja told reporters that four other people had Nipah-like symptoms. (reuters.com)
  • FILE PHOTO: Doctors and relatives wearing protective gear carry the body of a victim, who lost his battle against the brain-damaging Nipah virus, during his funeral at a burial ground in Kozhikode, in the southern Indian state of Kerala, India, May 24, 2018. (reuters.com)
  • Nipah virus has now hit Kerala. (financialexpress.com)
  • In the wake of deaths of several people in Kerala in the past fortnight due to 'Nipah' virus, the state health department has been put on high alert. (financialexpress.com)
  • In a tweet, Union Health Minister Jagat Prakash Nadda today said, "Reviewed the situation of deaths related to Nipah virus in Kerala with Secretary Health. (financialexpress.com)
  • The Nipah virus has so far claimed 11 lives in Kerala, including three members of a family and eight others who showed similar symptoms in Kozhikode and Malappuram. (financialexpress.com)
  • According to updates from the Office of Chief Minister of Kerala, CM Pinarayi Vijayan has informed that the Government is closely monitoring the spread of the Nipah virus. (financialexpress.com)
  • Two others have tested positive for Nipah and are considered critically ill, and more than three dozen people have been put into quarantine since the outbreak began in Kerala, according to BBC News. (ndtv.com)
  • But the virus's spread - and the rapidly rising death toll - have prompted concern in the outbreak's epicenter, Kozhikode, a coastal city in Kerala, where people have been "swarming" hospitals with fevers and other illnesses to ensure they do not have the virus, a local government official told Reuters. (ndtv.com)
  • Gulf News reported that Kerala "is in a state of panic after many cases of the killer Nipah virus were detected. (ndtv.com)
  • WHO has been informed about Nipah virus cases being reported in a family from a village in Kozhikode district of Kerala," he said. (ndtv.com)
  • Even when the final green signal came from Kerala health authorities that the fear of the spread has been contained, the source of the virus outbreak was yet to be ascertained. (ndtv.com)
  • The newest virus outbreak struck the tropical coast of Kerala, India this May. (internationalsos.com)
  • Health officials in the state of Kerala are on high alert after tests on animals thought to be carriers for the Nipah virus, including bats, cattle, goats and pigs, showed no sign of the disease. (rt.com)
  • According to the reports, ten people have lost their lives to the Nipah virus in northern Kerala districts of Kozhikode and Malappuram. (biospectrumasia.com)
  • With so many number of cases already reported in Kerala, the virus is currently a major threat to human health. (biospectrumasia.com)
  • In view of the rising number of cases and reported deaths due to Nipah Virus in Kozhikode, Kerala, J P Nadda, Union Minister of Health and Family Welfare has assured all support to the Kerala Government and has directed a multi-disciplinary Central team from National Centre for Disease Control to immediately visit the district, and assist the State and closely monitor the situation. (biospectrumasia.com)
  • As per the statement given by KK Shylaja, health minister of Kerala, "10 deaths were due to the nipha virus and that the World Health Organisation (WHO) has been informed about the outbreak of the virus in Kerala. (biospectrumasia.com)
  • Talking about the current situation of the disease in state, Pinarayi Vijayan, Chief Minister of Kerala said, "The state government was taking all steps to control Nipah virus. (biospectrumasia.com)
  • The Union Minister for Health & Family Welfare, J P Nadda is closely monitoring the situation arising out of reported cases and deaths due to Nipah Virus in Kerala. (biospectrumasia.com)
  • The number of deaths from the contagious Nipah virus infection in Kerala may have touched 14 with two more reported on Tuesday even as state and central health agencies stepped up efforts to contain the spread of the deadly virus. (hindustantimes.com)
  • Both patients are from Kerala and one of them had recently met with one of the people infected with Nipah virus in Kerala, according to reports from Mangaluru. (hindustantimes.com)
  • Kerala CM Pinarayi Vijayan on Monday said although Nipah-related deaths have been reported only in Kozhikode, the entire state has been put on alert, and private hospitals have been asked to not deny treatment to any patient with suspected symptoms. (indianexpress.com)
  • Kerala Health Services director Dr R L Saritha said, "So far three cases have been virologically confirmed as caused by Nipah. (indianexpress.com)
  • The fluid samples of a jawan, who died here days after returning from his hometown in Kerala, has tested 'negative' for Nipah virus infection, a defence official said today. (financialexpress.com)
  • There is currently an outbreak of Nipah in India in a new location, where the death toll has risen to 10 in India's southern state of Kerala. (globenewswire.com)
  • Kerala Health Minister KK Shailaja who has been leading from the front, the state's fightback against the virus said no new cases have been reported in the state. (indiatimes.com)
  • Union Health Minister Harsh Vardhan who is also monitoring the situation in the state confirmed that no new case of Nipah virus infection has been reported in Kerala. (indiatimes.com)
  • Kerala Health Minister said the state was able to act in such swift manner as they were anticipating the relapse of the deadly virus. (indiatimes.com)
  • Last year, the virus killed 17 people in Kerala. (passporthealthusa.com)
  • DUBAI/MUMBAI (Reuters) - The United Arab Emirates (UAE) has banned imports of fresh vegetables and fruits from the southern Indian state of Kerala where 13 people have died due to an outbreak of the rare brain-damaging Nipah virus, the Gulf state said on Tuesday. (physiciansweekly.com)
  • As many as 16 people lost their lives in Kerala due to the outbreak of the virus in May. (aninews.in)
  • Nipah virus infection is a severe endemic that has recently hit the city, Kochikode, Kerala. (yashodahospitals.com)
  • Though, the disease may not be an immediate threat for states other than Kerala, it is still important for us all to be aware about the ways to prevent and manage Nipah virus infections and its symptoms. (yashodahospitals.com)
  • The current endemic in Kerala is an infectious sequel of similarly serious Nipah outbreaks in several districts of West Bengal from 2001 to 2008. (yashodahospitals.com)
  • The Kerala health department is on a high alert as the deadly Nipah virus has caused a public health scare. (avivaindia.com)
  • Scientists have launched a multi-agency effort to contain the Nipah virus outbreak in Kerala, which has claimed six lives so far, including that of two brothers and a nursing assistant who treated them, officials told The Indian Express. (echarcha.com)
  • As of June 6, Nipah virus had claimed 16 lives out of 18 laboratory-confirmed cases in Kerala, a case fatality rate of 88.9 percent. (cdc.gov)
  • The death toll due to Nipah rose to 13 in Kerala, with one more person succumbing to the deadly virus here on Sunday. (deccanherald.com)
  • As samples of insectivores bats tested negative for the virus, the Kerala Animal Husbandry Department and the Pune based National Virology Institute (NVI) are jointly collecting samples of fruit-eating bats to be sent for expert tests. (deccanherald.com)
  • H1N1 In Rajasthan: Can The Nipah Outbreak In Kerala Offer Lessons? (eurasiareview.com)
  • In India, there have been three known outbreaks of Nipah, the latest in Kerala during which 21 of the 23 people affected with the virus died. (eurasiareview.com)
  • Out of 23 cases of Nipah in Kerala - the index case, 18 confirmed cases, and four probable cases - all 22 contracted the virus in hospital settings, where the index case or primary cases sought care. (eurasiareview.com)
  • Given the scale and spread of H1N1 in Rajasthan, its seasonal character as well as low mortality rates, similar levels of isolation of cases, contact tracing, and enforcement of hospital infection control practices as was seen during the Nipah outbreak in Kerala may not be warranted, nor will that be practical in Rajasthan. (eurasiareview.com)
  • This is the first detection in Kerala of the Nipah virus which has a high fatality rate and spreads mainly through bats, pigs and other animals. (udaipurkiran.in)
India29
Sungai Nipah11
20185
Fruit bats33
Bats46
Henipavirus16
Cases of Nipah virus4
199816
Centers for Diseas5
  • Adapted from Nipah virus distribution map, Centers for Disease Control and Prevention ( www.cdc.gov/vhf/nipah/outbreaks/distribution-map.html ). (asm.org)
  • The U.S. National Institutes of Health and U.S. Centers for Disease Control and Prevention both classify the Nipah virus and the Hendra virus as biothreat agents. (drugs.com)
  • Since the virus is a biosafety level 4 pathogen, TSRI researchers can only look at parts of it but not the entire virus, so the scientists are collaborating with the Centers for Disease Control and Prevention to look at the role of this structure in infection. (healthcanal.com)
  • The Nipah virus has been classified by the Centers for Disease Control and Prevention as a Category C agent. (blogspot.com)
  • According to Centers for Disease Control and Prevention, infection with Nipah virus is associated with encephalitis (inflammation of the brain). (technologytimes.pk)
199910
Malaysia7
Infection with Nipah virus3
Glycoprotein14
Anti-Nipah virus2
Pigs19
Deadly13
Pteropus3
  • Given the relatedness of NiV to Hendra virus , bat species were quickly singled out for investigation and flying foxes of the genus Pteropus were subsequently identified as the reservoir for NiV ( Distribution Map ). (cdc.gov)
  • Host del virus murciélagos frugívoros de la familia Pteropodidae, que pertenece al género Pteropus. (gentaur.com)
  • Pteropus rufus, Eidolon dupreanum )11 and Ghana ( Eidolon helvum )12 indicating a wide geographic distribution of the viruses. (who.int)
Antibodies4
Case of Nipah virus2
Symptoms of Nipah virus2
Treatment for Nipah virus2
Kozhikode7
  • According to state government figures, the Nipah virus had claimed 17 lives -- 14 in Kozhikode and three in neighbouring Malappuram in May last year. (sify.com)
  • A statewide alert has been given to remain vigilant, although the virus has been reported only in Kozhikode. (financialexpress.com)
  • Hospital staff wears safety masks as a precautionary measure at the Kozhikode Medical College where patients infected with the Nipah virus are being treated. (hindustantimes.com)
  • With three more suspected Nipah virus-related deaths reported over the last 24 hours in Kerala's Kozhikode district, where three deaths have already been confirmed, the entire state has been put on high alert, even as the Centre launched a multi-agency effort to contain the outbreak. (indianexpress.com)
  • A team from the National Centre for Disease Control, led by its director Dr Sujith Kumar Singh, on Monday visited the medical college in Kozhikode and affected areas to help the state tackle Nipah-induced fever. (indianexpress.com)
  • A statement from Kerala's Health Minister K K Shylaja said a task force has been constituted and a special intensive care unit and isolation ward have been arranged at Kozhikode medical college to address suspected Nipah cases. (indianexpress.com)
  • Apart from the six deaths, officials said, at least eight others are undergoing treatment in Kozhikode for complications linked to the virus. (echarcha.com)
Supportive care4
Disease18
  • Virus isolation attempts and real time polymerase chain reaction (RT-PCR) from throat and nasal swabs, cerebrospinal fluid, urine, and blood should be performed in the early stages of disease. (cdc.gov)
  • Nipah virus (NiV) infection is a disease associated with encephalitis, also known as inflammation of the brain. (financialexpress.com)
  • There is currently no treatment or preventative vaccine to treat the virus but the World Health Organization has listed Nipah as a 'Blueprint priority disease' for urgent research in February, due to its "potential to cause a public health emergency and the absence of efficacious drugs and/or vaccines" 5 . (internationalsos.com)
  • Nipah virus disease is a disease caused by a dangerous virus. (wikipedia.org)
  • Virus can also be identified by examining the tissues of persons who died of the disease. (wikipedia.org)
  • There are currently no approved vaccines for prevention of infection and disease caused by Nipah and Hendra for use by people or livestock," corresponding author Christopher Broder, a professor of microbiology at the Uniformed Services University in Bethesda, Md., said in a university news release. (drugs.com)
  • Nipah virus, a bat-borne paramyxovirus found throughout South and South East Asia, has been identified by WHO as an emerging infectious disease that may cause severe epidemics in the near future. (eurekalert.org)
  • With a case fatality of >70% and no available treatment or vaccines, Nipah virus was identified by the World Health Organization as an emerging infectious disease that may cause major epidemics if the pathogen evolves to become more transmissible, leading the organization to prioritize it for research to prevent future health emergencies. (eurekalert.org)
  • The statistics are frightening - more than 80 per cent of horses that contract the Hendra virus die, and four out of seven people who have contracted the disease from horses have died. (pearltrees.com)
  • The models are derived by homology modeling with the known structure of the F protein of Newcastle disease virus . (nih.gov)
  • It is, according to Dr. Jonathan Epstein, who's been studying Nipah for 15 years, " the worst disease no one has ever heard of . (ecohealthalliance.org)
  • FMD is the most worrying disease because of the severe impact of new strains of the virus on cattle and pig production. (pighealth.com)
  • In addition to acute infection, these viruses cause asymptomatic infection in up to 60% of exposed people, and may lead to late-onset disease or relapse of encephalitis years after initial infection , as well as persistent or delayed neurological sequelae. (prolekare.cz)
  • The ordinary differential equation (ODE) model describes experimental results for human monocyte derived dendritic cells (DCs) infected by individual Nipah virus immune antagonists (P, V, and W) expressed in recombinant Newcastle disease viruses. (mssm.edu)
  • Although no specific treatment can destroy the virus once the disease has become established, many types of encephalitis can be prevented by immunization. (thefreedictionary.com)
  • Antioxidant treatment ameliorates respiratory syncytial virus-induced disease and lung inflammation. (microbiologyresearch.org)
  • Nipah virus is an emerging infectious disease of public health importance. (cdc.gov)
  • Nipah Virus Infection (NiV) is an emerging infectious disease of public health importance in the South-East Asia Region. (who.int)
Paramyxoviridae1
Vaccines5
Pathogen3
  • Nipah is on the WHO's research and development "priority pathogen" list alongside Ebola, Zika, MERS, Lassa and Crimean-Congo haemorrhagic fever. (reuters.com)
  • Less than one year later, scientists at MCVR used those skills, including NGS, to detect Nipah virus as the pathogen responsible for the outbreak and identified the exact strain of the virus. (cdc.gov)
  • Nipah Virus is the most dangerous pathogen. (ekincare.com)
Genus2
Flying foxes1
Pathogens4
  • EcoHealth Alliance has been studying Nipah virus for 15 years and our experts advised WHO as they developed their list of the ten most important pathogens. (ecohealthalliance.org)
  • Nipah virus and Hendra virus are RNA viruses in the family of paramyxoviruses, making them distant cousins of human pathogens such as measles, mumps, respiratory syncytial, and Newcastle viruses. (miragenews.com)
  • MCVR's ongoing partnerships with Kerala's state health services and private sector partners, beginning with pandemic Influenza A/H1N1 in 2009, as well as its work under GHSA with international partners like CDC on detection of emerging pathogens, were crucial in detecting the Nipah virus infection so quickly," said Dr. Arunkumar Govindakarnavar, who serves as the head of MCVR. (cdc.gov)
  • Nipah virus (NiV) is one of the pathogens in the WHO R&D (Research and Development) Blueprint list of epidemic threats needing urgent R&D attention. (technologytimes.pk)
20191
Paramyxovirus3
Discovered in Australia in 19942
People infected with Nipah virus1
  • The first people infected with Nipah virus are believed to have been pig farm workers living near Ipoh, Malaysia's third biggest city, in January 1997. (www.csiro.au)
Spread of the Nipah virus1
  • The spread of the Nipah virus illustrates a problem due to trends in livestock production -- large-scale production and international commerce. (drugster.info)
Virology5
  • The results of blood samples of the student, which were tested at the National Institute of Virology in Pune, have confirmed Nipah, state Health minister K K Shailaja said here. (sify.com)
  • National Institute of Virology has confirmed from the studies on blood samples that three out of the four deaths attributed to fever was caused by the virus. (financialexpress.com)
  • The researchers, led by Dr. Heinz Feldmann, chief of the Rocky Mountain Laboratories' Laboratory of Virology, conducted their research on live Nipah virus in a high-security facility in Hamilton, Mont. (drugs.com)
  • A day later, he was dead - but not before his doctors noticed his symptoms were consistent with encephalitis.Recognizing the potential danger, they immediately sent samples from the patient to the Manipal Centre for Virus Research (MCVR), followed by the National Institute of Virology (NIV) in Pune, where laboratory tests identified the cause of death as Nipah virus. (cdc.gov)
  • The Virus Research Diagnostic Laboratory at Manipal Hospital and the National Institute of Virology are geared up to meet any diagnostic challenges that may arise. (udaipurkiran.in)
Recombinant8
  • In this study, we established a system that enabled the rescue of replicating NiVs from a cloned DNA by cotransfection of a constructed full-length cDNA clone and supporting plasmids coding virus nucleoprotein, phosphoprotein, and polymerase with the infection of the recombinant vaccinia virus, MVAGKT7, expressing T7 RNA polymerase. (pnas.org)
  • Since the vaccine is only a recombinant piece of the virus, it can be produced by itself and purified. (drugs.com)
  • This work now provides key evidence that a simple and safe recombinant vaccine against Nipah virus is possible," study co-author Thomas Geisbert, professor in the department of microbiology and immunology at the University of Texas Medical Branch and the Galveston National Laboratory, said in the news release. (drugs.com)
  • Since the vaccine is just a recombinant piece of the virus, it is a type of vaccine known as a subunit, thus making it extremely safe to use," Dr. Bossart said. (globenewswire.com)
  • The present invention provides a recombinant matrix protein of Nipah virus containing matrix protein of nipah virus which includes at least ine His tag and MYC epitope. (upm.edu.my)
  • Further, the present invention also provides a recombinant plasmid including recombinant matrix protein of Nipah virus. (upm.edu.my)
  • There is also provided a pharmaceutical composition comprising a therapeutically affective amount of recombinant matrix protein of Nipah virus. (upm.edu.my)
  • Also provided is a diagnostic reagent comprising an effective amount of recombinant matrix protein matrix of Nipah virus. (upm.edu.my)
Epidemic5
Diseases7
Source of Nipah virus2
  • Now a days various messages on social media warns Pakistani nation to avoid chicken consumption, because its source of Nipah virus. (technologytimes.pk)
  • For any layperson it is confusing and debatable either chicken is source of Nipah virus or not, mostly said no its fake news, chicken is safe its not the cause of spread, other said avoid the chicken consumption because, prevention is better than cure. (technologytimes.pk)
Vaccine for Nipah virus2
Presence of Nipah virus1
  • Dr Sanjeev Singh, medical director at the institute, said that Atifa comes from Perambra taluk of Kohhikode, where presence of Nipah virus has been confirmed, and was admitted as a precautionary measure when she also developed symptoms of fever after her fiance succumbed to the virus. (indianexpress.com)
Severe5
Isolation3
  • The study showed in particular that adult cases with respiratory symptoms transmitted the virus to more individuals than other cases, and might therefore be targeted for interventions when the isolation of all suspected Nipah cases is not possible. (eurekalert.org)
  • As explained by Birgit Nikolay, first author of the study, « the results of this study help identify patients that should be targeted for interventions such as isolation measures if resources are insufficient to cover all suspected Nipah cases. (eurekalert.org)
  • enzyme-linked immunosorbent assay (ELISA) -polymerase chain reaction (PCR) assay -virus isolation by cell culture. (ind91.com)
Measles2
  • In our empirical force field-based simulations, characteristic structures and helicities of α-MoREs reveal the co-existence of partially structured and disordered conformations, as in the case of the well characterized cognate measles virus (MeV) α-MoRE. (nih.gov)
  • It was surprising to us that this structure is so similar to those from measles and mumps viruses, even though they are only 5 to 26% identical in sequence," Bruhn said. (healthcanal.com)
Inflammation of the brain4
Prevention3
Monoclonal2
Infects2
Diagnosis2
Neurological2