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  • various neuropeptides
  • We employ genetic, molecular, anatomical, viral, optogenetic and behavioral approaches to study the effects of addressed axonal release of various neuropeptides within the distinct brain regions controlling stress and fear responses, maternal and social behavior. (dkfz.de)
  • pharmacology
  • We attempt to highlight what is known about these two key gonadal neuropeptides, how their actions differ from their hypothalamic counterparts, and how we might learn from comparative studies of them and other gonadal neuropeptides in terms of pharmacology, reproductive physiology and evolutionary biology. (frontiersin.org)
  • molecular
  • Our laboratory is focused on the dissection of the mechanisms of neuropeptide action in the brain, from molecular via anatomical to the whole organism level. (dkfz.de)
  • bind
  • Further, our knowledge of the control of these gonadal neuropeptides by peripheral hormones that bind to the gonads, and which themselves are under regulation by true neuropeptide systems from the hypothalamus, is relatively meager. (frontiersin.org)
  • pharmacological
  • This article focuses on "neuropeptides" in the gonads of vertebrates, with special emphasis on what we can learn from pharmacological experiments on gonadal tissue and then apply to our understanding of an animal's ecology in the wild. (frontiersin.org)
  • Proliferation
  • The dentate gyrus is significantly involved in cell proliferation, a process modulated by various internal factors including Neuropeptide Y. Reduction or elimination of NPY released by interneurons decreased cell growth in this brain area. (wikipedia.org)
  • human
  • Furthermore, our group uses animal models of psychiatric diseases, including anxiety disorders and autism, to study the possible contribution of neuropeptides to the pathogenesis of the respective human diseases. (dkfz.de)
  • In contrast with rat and cow brains, the human brain contains larger amounts of neuropeptide K. Dornan WA, Vink KL, Malen P, Short K, Struthers W, Barrett C (August 1993). (wikipedia.org)