• various neuropeptides
  • We employ genetic, molecular, anatomical, viral, optogenetic and behavioral approaches to study the effects of addressed axonal release of various neuropeptides within the distinct brain regions controlling stress and fear responses, maternal and social behavior. (dkfz.de)
  • Proliferation
  • The dentate gyrus is significantly involved in cell proliferation, a process modulated by various internal factors including Neuropeptide Y. Reduction or elimination of NPY released by interneurons decreased cell growth in this brain area. (wikipedia.org)
  • human
  • Furthermore, our group uses animal models of psychiatric diseases, including anxiety disorders and autism, to study the possible contribution of neuropeptides to the pathogenesis of the respective human diseases. (dkfz.de)
  • Human neuropeptide Y (hNPY) was synthesized in a conventional manner by assembling seven peptide fragments followed by reduction of the Met(O) residue with phenylthiotrimethylsilane and subsequent deprotection with 1 M trimethylsilyl trifluoromethanesulfonate (TMSOTf)-thioanisole in trifluoroacetic acid (TFA). (biomedsearch.com)
  • In contrast with rat and cow brains, the human brain contains larger amounts of neuropeptide K. Dornan WA, Vink KL, Malen P, Short K, Struthers W, Barrett C (August 1993). (wikipedia.org)