DiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and ProcessesHealth Care
Breakthrough PainAdministration, BuccalFentanylAnalgesics, OpioidLabor PainPainAnalgesia, EpiduralPain MeasurementNasal SpraysDouble-Blind MethodNeoplasmsChronic DiseasePain, PostoperativeChronic PainPain ManagementPain ThresholdPain, IntractableRadionuclide GeneratorsLow Back PainBack PainAnesthetics, IntravenousAbdominal PainNeck PainTreatment OutcomeTime FactorsMorphineEpisode of CareAdministration, CutaneousAerosolsPelvic PainFacial PainPain PerceptionBupivacaine
VisceralAcute or chronicOpioidPatient'sCloselyAssessmentHealthcarePatientsCombinationDrugTreatment of PainManagementTherapyFrequentlyRiskCitrateIntrathecal2020OpioidsIncidenceReducesPainfulDrugsSpinalSensoryAssessmentDisordersManageCancer patientsRelativeDefinitionMedicalExpertReliefTransferResponsibleReviewPreventTreatment
Visceral1
  • The almost immediate onset of fentanyl reduces visceral discomfort and even nausea during the procedure. (wikipedia.org)
Acute or chronic2
Opioid6
  • Fentanyl, also spelled fentanil, is a highly potent synthetic piperidine opioid drug primarily used as an analgesic. (wikipedia.org)
  • Fentanyl works by activating mu-opioid receptors. (wikipedia.org)
  • Fentanyl continues to fuel an epidemic of synthetic opioid drug overdose deaths in the United States. (wikipedia.org)
  • Fentanyl is the most commonly used intrathecal opioid because its lipophilic profile allows a quick onset of action (5-10 min) and intermediate duration of action (60-120 min). (wikipedia.org)
  • Nonopioid and opioid analgesics are the main drugs used to treat pain. (msdmanuals.com)
  • Patients with cancer or noncancer pain requiring chronic therapy are monitored closely to optimize treatment and to minimize the likelihood of complications of opioid use, including misuse or abuse. (tri-kobe.org)
Patient's2
  • These interventions include counseling to refocus a patient's thoughts from the effects and limitations of pain to the development of personal coping strategies and may include counseling to help patients and their family work together to manage pain. (msdmanuals.com)
  • Regular screening to ensure that the patient's pain is recognized early. (tri-kobe.org)
Closely1
  • In obstetrics, the dose must be closely regulated in order to prevent large amounts of transfer from mother to fetus. (wikipedia.org)
Assessment1
  • Refer to the Pain Assessment section of this summary for more information. (tri-kobe.org)
Healthcare1
  • This course is designed for physicians, physician assistants, nurses, social workers, and other members of the healthcare team seeking to enhance their knowledge of pain management. (netce.com)
Patients5
  • Because fentanyl is 50 to 100 times more potent than morphine, its primary clinical utility is in pain management for cancer patients and those recovering from painful surgical operations. (wikipedia.org)
  • Cognitive-behavioral interventions may reduce pain and pain-related disability and help patients cope. (msdmanuals.com)
  • Overview of Pain Pain is the most common reason patients seek medical care. (msdmanuals.com)
  • Pain is one of the most common symptoms in cancer patients and often has a negative impact on patients' functional status and quality of life. (tri-kobe.org)
  • [ 3 ] Pain is commonly experienced by cancer patients. (tri-kobe.org)
Combination1
Drug5
  • Since 2018, fentanyl and its analogues have been responsible for most drug overdose deaths in the United States, causing over 71,238 deaths in 2021. (wikipedia.org)
  • Fentanyl constitutes the majority of all drug overdose deaths in the United States since it overtook heroin in 2018. (wikipedia.org)
  • Balancing this medication and titrating the drug based on expected stimuli and the person's responses can result in stable blood pressure and heart rate throughout a procedure and a faster emergence from anesthesia with minimal pain. (wikipedia.org)
  • At high doses, the drug may act on the fetus to cause postnatal respiratory distress. (wikipedia.org)
  • This effect appears to vary by specific drug, as well as by dose and duration. (msdmanuals.com)
Treatment of Pain1
  • This PDQ cancer information summary for health professionals provides comprehensive, peer-reviewed, evidence-based information about the pathophysiology and treatment of pain. (tri-kobe.org)
Management1
  • The goal of the following summary is to provide evidence-based, up-to-date, and practical information on the management of cancer pain. (tri-kobe.org)
Therapy1
  • Antidepressants, antiseizure drugs, and other central nervous system (CNS)-active drugs may also be used for chronic or neuropathic pain and are first-line therapy for some conditions. (msdmanuals.com)
Frequently2
  • Because pain is frequently encountered in the palliative and hospice care environments, a knowledge of appropriate diagnosis and alleviation is vital to all members of the interdisciplinary team. (netce.com)
  • Acute pain is frequently associated with anxiety. (msdmanuals.com)
Risk1
Citrate3
Intrathecal3
  • Fentanyl is the most commonly used intrathecal opioid because its lipophilic profile allows a quick onset of action (5-10 min) and intermediate duration of action (60-120 min). (wikipedia.org)
  • INTERVENTIONS: Combined spinal-epidural labor analgesia was initiated with intrathecal fentanyl and epidural analgesia was maintained using continuous epidural infusion with patient-controlled epidural boluses. (bvsalud.org)
  • Also, differences in the initiation of epidural analgesia such as combined spinal-epidural (CSE) (medications given into the intrathecal space in addition to the epidural space) compared to epidural only, and medications used (types and doses of LA or opioids) may not have been accounted for in previous reviews. (bvsalud.org)
20202
  • The United States National Forensic Laboratory estimates fentanyl reports by federal, state, and local forensic laboratories increased from 4,697 reports in 2014 to 117,045 reports in 2020. (wikipedia.org)
  • In 2020, the International Association for the Study of Pain (IASP) revised its definition of pain for the first time since 1979 to the following: "an unpleasant sensory and emotional experience associated with, or resembling that associated with, actual or potential tissue damage" (IASP, 2020). (nursingce.com)
Opioids1
  • It will also discuss the core aspects of prescribing opioids for pain, including best-practice opioid prescribing guidelines, proper monitoring of patients on long-term opioid therapy, and the clinical features of opioid misuse/OUD. (nursingce.com)
Incidence3
  • The superior method of delivering epidural medications would result in lower incidence of pain requiring anaesthesiologist intervention (breakthrough pain). (bvsalud.org)
  • Our prior systematic review suggested that AMB reduces the incidence of breakthrough pain compared to BI with no significant difference in the incidence of caesarean delivery or instrumental delivery, duration of labour analgesia, and LA consumption. (bvsalud.org)
  • Donovan M, Dillon P, McGuire L. Incidence and characteristics of pain in a sample of medical-surgical inpatients. (medscape.org)
Reduces1
  • The almost immediate onset of fentanyl reduces visceral discomfort and even nausea during the procedure. (wikipedia.org)
Painful2
  • Because fentanyl is 50 to 100 times more potent than morphine, its primary clinical utility is in pain management for cancer patients and those recovering from painful surgical operations. (wikipedia.org)
  • Fundamentally, pain is felt when sensory nerve endings called nociceptors (or pain receptors) come in contact with a noxious (painful) stimulus. (nursingce.com)
Drugs3
  • Fentanyl is often mixed, cut, or ingested alongside other drugs, including cocaine and heroin. (wikipedia.org)
  • Fentanyl has been reported in pill form, including pills mimicking pharmaceutical drugs such as oxycodone. (wikipedia.org)
  • Antidepressants, antiseizure drugs, and other central nervous system (CNS)-active drugs may also be used for chronic or neuropathic pain and are first-line therapy for some conditions. (msdmanuals.com)
Spinal2
  • Spinal administration of hyperbaric bupivacaine with fentanyl may be the optimal combination. (wikipedia.org)
  • Fentanyl is sometimes given intrathecally as part of spinal anesthesia or epidurally for epidural anaesthesia and analgesia. (wikipedia.org)
Sensory2
  • Pain has sensory and emotional components and is often classified as acute or chronic. (msdmanuals.com)
  • BACKGROUND: Epidural analgesia is often used for pain relief during labour and childbirth, and involves administration of local anaesthetics (LA) into the epidural space resulting in sensory blockade of the abdomen, pelvis, and perineum. (bvsalud.org)
Assessment2
  • Consensus panel recommendations for the assessment and management of breakthrough pain: Part I Assessment. (medscape.org)
  • A prospective multicenter assessment of the Edmonton staging system for cancer pain. (medscape.org)
Disorders1
  • Chemical pain is associated with inflammatory disorders, and thermal pain is due to excessive heat or cold exposure. (nursingce.com)
Manage2
  • These interventions include counseling to refocus a patient's thoughts from the effects and limitations of pain to the development of personal coping strategies and may include counseling to help patients and their family work together to manage pain. (msdmanuals.com)
  • J Pain Symptom Manage. (medscape.org)
Cancer patients1
  • A survey of pain-related hospitalizations, emergency department visits, and physician office visits reported by cancer patients with and without history of breakthrough pain. (medscape.org)
Relative1
  • It is widely used in obstetrical anesthesia because of its short time to action peak (about 5 minutes), the rapid termination of its effect after a single dose, and the occurrence of relative cardiovascular stability. (wikipedia.org)
Definition1
  • Breakthrough pain: definition, prevalence and characteristics. (medscape.org)
Medical2
  • Fentanyl was first synthesized by Paul Janssen in 1959 and was approved for medical use in the United States in 1968. (wikipedia.org)
  • Hwang SS, Chang VT, Kasimis B. Cancer breakthrough pain characteristics and responses to treatment at a VA medical center. (medscape.org)
Expert1
  • Episodic (breakthrough) pain: consensus conference of an expert working group of the European Association for Palliative Care. (medscape.org)
Relief1
  • For pain relief after surgery, use can decrease the amount of inhalational anesthetic needed for emergence from anesthesia. (wikipedia.org)
Transfer1
  • In obstetrics, the dose must be closely regulated in order to prevent large amounts of transfer from mother to fetus. (wikipedia.org)
Responsible2
  • Since 2018, fentanyl and its analogues have been responsible for most drug overdose deaths in the United States, causing over 71,238 deaths in 2021. (wikipedia.org)
  • Neurons are messengers in the body responsible for connecting, receiving, and processing pain. (nursingce.com)
Review1
  • Breakthrough pain in malignant and non-malignant diseases: a review of prevalence, characteristics and mechanisms. (medscape.org)
Prevent1
  • The purpose of pain is to prevent tissue damage and protect the body while healing, although its etiology is complex and multifaceted. (nursingce.com)
Treatment3
  • The treatment of cancer pain. (medscape.org)
  • Peteet J, Tay V, Cohen G, MacIntyre J. Pain characteristics and treatment in an outpatient cancer population. (medscape.org)
  • Cancer-related pain: a pan-European survey of prevalence, treatment, and patient attitudes. (medscape.org)