Neuronal communication cell communication. Medical search. Frequent questions

In this webinar, Dr. P. Joel Ross (The Hospital for Sick Children, Toronto) describes how patient-specific iPS cell-derived neurons can be functionally characterized and used to identify neurodevelopmental disorder-associated neuronal phenotypes. (stemcell.com)
The communication mechanisms deployed by plants aren't a more primitive version of animal neurons, however, as they boast their own unique communication systems. (upi.com)
The L1CAM gene provides instructions for producing the L1 cell adhesion molecule protein (shortened to L1 protein), which is found on the surface of nerve cells (neurons) throughout the nervous system. (medlineplus.gov)
This positioning allows the L1 protein to attach (bind) to other proteins, including other L1 proteins, on neighboring neurons to help these cells stick to one another (cell-cell adhesion). (medlineplus.gov)
The protein also plays a role in the formation of the protective sheath (myelin) that surrounds certain neurons and the formation of junctions between nerve cells (synapses), where cell-to-cell communication occurs. (medlineplus.gov)
Cell assemblies and central pattern generators (CPGs) are related types of neuronal networks: both consist of interacting groups of neurons whose collective activities lead to defined functional outputs. (degruyter.com)
Consequently, the intrinsic properties and pairwise interactions of their constituent neurons can be characterized, including analyses of their communication via gap junctions, action potential-gated synapses or graded synapses. (degruyter.com)
It is likely that constituent neurons in a cell assembly can be spread over large territories, intermixed with many other neurons ( Wallace and Kerr, 2010 ). (degruyter.com)
Researchers also treated an extensively tested line of neuronal cells with Rhosin, along with nerve growth factor, a protein that is important to the growth and survival of neurons. (cincinnatichildrens.org)
Neurites are young or early stage extensions from neurons required for neuronal communications. (cincinnatichildrens.org)
Transplantation of neural progenitor cells (NPC) is a promising therapeutic strategy for replacing neurons lost after spinal cord injury, but significant challenges remain regarding neuronal integration and functional connectivity. (jneurosci.org)
Here we tested the ability of graft-derived neurons to reestablish connectivity by forming neuronal relays between injured dorsal column (DC) sensory axons and the denervated dorsal column nuclei (DCN). (jneurosci.org)
To get a good handle on the extent of simultaneous neuronal activity, he and his former postdoctoral fellow, Dr. Longnian Lin, first developed a technique to record the activity of up to 200 mouse neurons, rather than the 20 to 30 previously possible. (sciencedaily.com)
In neurons, most proteins are synthesized in the cell body and must be transported through thin structures over long distances where normal diffusion is insufficient. (nature.com)
Hybrid in composition and function between the two hitherto known types of brain cells - neurons and glial cells - these cells of a new order are found in several brain regions from mice to humans. (myscience.ch)
The two main families of cells that make up the brain - neurons and glial cells - were secretly hiding a hybrid cell, halfway between these two categories. (myscience.ch)
Some of these glial cells, known as astrocytes, intimately surround synapses, the points of contact where neurotransmitters are released to transmit information between neurons. (myscience.ch)
These are cells that modulate neuronal activity, controlling the level of communication and excitation of neurons", explains Roberta de Ceglia, researcher at the University of Lausanne and first author of the study. (myscience.ch)
Toni N ., Song H., Ming GL "Tangential migration of neuronal precursors of glutamatergic neurons in the adult mammalian brain", PNAS 2015 July 13. (chuv.ch)
Cam kinase-Gr is also evident in the axons of granule cells and present to a lesser extent in the cytoplasm and dendrites of these neurons. (epa.gov)
H5N1, for example, could easily infiltrate nerve cells in the brain and kill them, and it appeared to especially target the dopamine-producing neurons in the substantia nigra. (the-scientist.com)
Researchers say psychedelic drugs actually help neurons in the brain sprout new dendrites, which look like branches on a tree, to increase communication between cells. (cbs58.com)
These drugs can increase neuronal outgrowth, they can increase this branching of neurons, they can increase synapses. (cbs58.com)
Genes carry the fundamental information to build and maintain cells, including neurons. (edu.au)
Brain microdialysis is used to determine the factors/neurotransmitters that are released from neurons in the course of neuronal communication. (edu.au)
Brain function depends on the active communication between nerve cells, known as neurons. (technologynetworks.com)
These proteins are present, along with AMPA receptors, in the 'granule' cells, which are neurons that receive signals from areas outside of the hippocampus. (technologynetworks.com)
however, we present a new co-culture system in which neurons and astrocytes are independently generated from human embryonic stem cells and combined in co-cultures. (lu.se)
Implantable electrodes for long term monitoring and interaction with multiple neurons have the potential to provide such information but will only be useful if truly biocompatible, i.e. if they themselves do not cause significant tissue reactions such as inflammation, neuronal loss and glial encapsulation. (lu.se)
Ongoing work aims at investigating the impact of different types of nanostructured ultraflexible leads on nearby neurons and glia cells in the brain and recording properties. (lu.se)

Consistent with other studies, genes identified by disrupted protein interactions are expressed early in development and in excitatory and inhibitory neuronal lineages. (springer.com)
The interaction of a variety of excitatory and inhibitory neuronal systems influence the activity of the PMC, which by default attempts to trigger the voiding reflex. (medscape.com)

We here argue that electrical coupling - in addition to chemical synapses - may therefore contribute to the formation of at least some cell assemblies in adult animals. (degruyter.com)
They comprise intricate branching processes that envelop synapses and facilitate bidirectional communication. (news-medical.net)
We have identified a subgroup of astrocytes that respond to selective stimulation by rapidly releasing glutamate from spatially delimited areas of these cells reminiscent of synapses", says Andrea Volterra, Honorary Professor at the University of Lausanne, Visiting Faculty at the Wyss Center and co-director of the study. (myscience.ch)
Sanchez-Pascual I., O'Laoi R., El M'Ghari I., Kocher-Braissant J., Ellisman MH, Toni N . "Fine processes of Nestin-GFP positive radial glia-like stem cells in the adult dentate gyrus ensheathe local synapses and vasculature. (chuv.ch)
Microglia then consume neuronal synapses, the major points of communication between brain cells. (northdenvernews.com)

NMDA receptors are essentially small pores on cell membranes that let ions in and increase neuronal activity and communication. (sciencedaily.com)

Using inferred gene co-expression for three neuronal cell types-excitatory, inhibitory, and neural progenitor-we implicate several hundred genes in risk (FDR \(\le \hspace{0.17em}\) 0.05), ~ 60% novel, with characteristics of genuine ASD genes. (springer.com)
Across cell types, these genes affect neuronal morphogenesis and neuronal communication, while neural progenitor cells show strong enrichment for development of the limbic system. (springer.com)
Kenwrick S, Watkins A, De Angelis E. Neural cell recognition molecule L1: relating biological complexity to human disease mutations. (medlineplus.gov)
These findings provide the first evidence for the ability of NPC to form a neuronal relay by extending active axons across the injured spinal cord to the intended target establishing a critical step for neural repair with stem cells. (jneurosci.org)
Sandström J., Eggermann E., Charvet I., Roux A., Toni N ., Greggio C., Broyer A., Monnet-Tschudi F., Stoppini L. "Development and characterization of a human embryonic stem cell-derived 3D neural tissue model for neurotoxicity testing. (chuv.ch)
Gebara E., Bonaguidi M., Beckervordersandforth R., Sultan S., Udry F., Gijs P., Lie C., Ming G., Song H., Toni N . "Morpho-functional characterization of adult neural hippocampal stem cells reveals two morphotypes of radial glia-like cells. (chuv.ch)
Braun S., Moss J., Toni N. , Jessberger S. "Programming hippocampal neural stem/progenitor cells into oligodendrocytes enhances remyelination in the adult brain after injury" Cell Reports , 2015 Jun 23;11(11):1679-85. (chuv.ch)
Activation of neuronal genes via LINE-1 elements upon global DNA demethylation in human neural progenitors ", Nature Communications, 2020). (lu.se)
Per Ludvik Brattås (Jakobsson group) " TRIM28 Controls a Gene Regulatory Network Based on Endogenous Retroviruses in Human Neural Progenitor Cells " (Cell 2017). (lu.se)
Regarding animal models in ASD, many studies focus on gene expression, cortical neuronal migration and cell maturation, and neural network deficits. (bvsalud.org)

For genes encoding the disrupted interactions, we evaluate their expression patterns across developing brains and within specific cell types, using both bulk and inferred cell-type-specific brain transcriptomes. (springer.com)
Their gene expression during brain development and within cell types highlights how they relate to ASD. (springer.com)
Using the newly released and larger ASC dataset, we confirm these observations and take them in several new directions: (1) By defining a set of genes encoding these disrupted protein interactors in ASD subjects and another for their siblings, we evaluate their expression patterns in developing brain from fetal to early postnatal development and within general cell types of brain tissue. (springer.com)
It is likely that the L1CAM gene mutations that cause these features contribute to disruption of the normal migration and function of nerve cells in the brain and intestine, leading to hydrocephalus and Hirschsprung disease. (medlineplus.gov)
Coronal section of rat brain triple-labeled with fluoromyelin (green), DiI (red), and TO-PRO3 (blue) which stain for myelin, blood vessels, and cell bodies, respectively. (cellimagelibrary.org)
Astrocytes are specialized glial cells ubiquitously distributed throughout the spinal cord and brain. (news-medical.net)
Astrocytes are a heterogeneous population of cells with distinguishing functional and morphological characteristics and are specialized to their different brain regions and locations. (news-medical.net)
8 Astrocytes interact with blood vessels, pericytes, and epithelial cells to organize CNS flow and modulate the blood-brain barrier (BBB). (news-medical.net)
Rat primary astrocytes were isolated from different brain regions (cortex, cerebellum, and hippocampus) and grown in vitro to demonstrate the utilization of live-cell analysis for monitoring and comparing the diversity of cultured astroglia phenotypes. (news-medical.net)
Temporal monitoring of brain region astroglia revealed differences in cell growth and morphology. (news-medical.net)
The myelin sheaths of nerve cells in the human brain are lamellar membranes surrounding the neuronal axons. (mytum.de)
My doctoral research focuses on human stem cells derived neuronal models, such as brain organoids. (theconversation.com)
The identification of the molecular machinery required for the rapid release of neurotransmitters has led to the discovery of a new type of functional cell in the brain. (myscience.ch)
A research team from the University of Lausanne and the Wyss Center has discovered a new type of cell essential to brain function. (myscience.ch)
Inside the brain, interleukin-1 beta turns normally supportive microglial cells predatory. (northdenvernews.com)
The results were startling, he says: some viruses weren't blocked from entering the brain by the blood-brain barrier-a semipermeable layer of cells that separates the central nervous system from the body's circulation. (the-scientist.com)
1 And while the H1N1 flu strain couldn't cross the blood-brain barrier, it still caused central nervous system immune cells called microglia to flow into the substantia nigra and the hippocampus, causing inflammation and cell death in the area. (the-scientist.com)
Treatment typically involves selective serotonin reuptake inhibitors, or SSRIs, which boost levels of serotonin available to brain cells. (cbs58.com)
That's different from neurogenesis, which is the development of brand new brain cells, typically from stem cells in the body. (cbs58.com)
Proteins are essential for developing and maintaining neuronal structure and can function as transmitters, receptors, modulators and mediators in the brain. (edu.au)
Staining of brain slices or cells, previously fixed, is essential to examine neuronal morphology and connectivity. (edu.au)
Some compounds can serve as biochemical precursors of neuromediators, others may prevent oxidative damage to brain cells or provide them with a source of energy. (brainblogger.com)
These molecules, which have similar counterparts in humans, affect the connections between nerve cells and influence the transmission of nerve signals into the hippocampus, an area of the brain that plays a significant role in learning processes and the creation of memories. (technologynetworks.com)
A TBI can cause brain-cell death and tissue degeneration, potentially leading to many negative clinical symptoms for the patient, depending on the severity of the injury. (asbmb.org)
Brain Communications , 5 (3), 1-16. (lu.se)
The module provides students with basic knowledge of neuroanatomy, brain development and change, cellular function and communication, and basic brain functions, such as sensory processing, perception, motor function and motivation. (lu.se)
A cis-acting structural variation at the ZNF558 locus controls a gene regulatory network in human brain development", Cell Stem Cell, 2022. (lu.se)
Cognitive control of micturition is achieved by communication from a number of brain structures to the periaqueductal gray matter, which then exerts control over the pontine micturition center to suppress or trigger a voiding reflex. (medscape.com)

By identifying a new cell type with the characteristics of an astrocyte and expressing the molecular machinery required for synaptic transmission, neuroscientists from the Department of Basic Neuroscience in the Faculty of Biology and Medicine at the University of Lausanne (UNIL) and the Wyss Center for Bio and Neuroengineering in Geneva have put an end to years of controversy. (myscience.ch)
Thanks to the precision of single-cell transcriptomics techniques, we were able to identify transcripts of VGLUT proteins, responsible for filling neuronal vesicles to release glutamate, in cells with an astrocyte profile. (myscience.ch)
Overall, our data indicates that astrocyte alterations precede neuronal impairments and could potentially trigger neuronal network changes, indicating the important and specific role of astrocytes in disease development. (lu.se)

The Lund Stem Cell Center Article of the Year Award (2022 & 2023) ceremony will take place on Friday, 21 September during the SCC Annual Retreat 2023. (lu.se)
m6A-driven SF3B1 translation control steers splicing to direct genome integrity and leukemogenesis", Molecular Cell, 2023. (lu.se)

A mixed population of neuronal and glial restricted precursors (NRP/GRP) derived from the embryonic spinal cord of alkaline phosphatase (AP) transgenic rats were grafted acutely into a DC lesion at C1. (jneurosci.org)

Extracellular vesicles (EVs), including exosomes, are membranous particles released by cells into the extracellular space. (mdpi.com)
Proper transport of vesicles and their cargo to specific locations in the cell is critical in building and maintaining synaptic machinery as well as modulating synaptic plasticity 8 . (nature.com)
Moreover, we detected in these same cells other proteins crucial to the function of glutamatergic vesicles", explains Ludovic Telley, assistant professor at the University of Lausanne and co-director of the study. (myscience.ch)

Some findings showed critical genes, which modulate several aspects of verbal communication. (bvsalud.org)

This allows the monitoring and measuring of cell behaviors and phenotypes in a non-perturbing manner, over prolonged periods in real-time. (news-medical.net)
The Incucyte ® Live-Cell Analysis System delivers flexible kinetic quantification of biological phenotypes to monitor growth, motility, morphology, and cellular function. (news-medical.net)

Next, the neuroscientists investigated whether these hybrid cells were functional, i.e. capable of releasing glutamate at a rate comparable to that of synaptic transmission. (myscience.ch)
Moreover, this release of glutamate influences synaptic transmission and controls neuronal circuits. (myscience.ch)

I am using human pluripotent stem cells that carry either trisomy 21 or the fmr1 mutation to study the development of the cerebral cortex in vitro. (wisc.edu)
Here, we have generated a CHMP2B-mutated human embryonic stem cell line using genome editing with the purpose to create a human in vitro FTD disease model. (lu.se)

Plants don't have a central nervous system, but to communicate, their cells rely on proteins that look a lot like the glutamate receptors used by the neuronal cells of animals. (upi.com)
Unlike glutamate receptors in animals, which are found on the outside of cells, GLRs are most common on structures inside the walls of plant cells. (upi.com)
Others can accelerate neuronal communication through increased release of certain neuromediators or through agonistic effects on the receptors of these neuromediators. (brainblogger.com)
The researchers discovered, among other things, that both proteins promote the transportation of glutamate receptors to the cell surface. (technologynetworks.com)
However, the number of receptors and thus the signal reception can be altered by neuronal activity. (technologynetworks.com)

The number of mitochondria in a cell can vary widely by organism , tissue , and cell type. (wikipedia.org)
Less is known regarding its critical role in neuronal physiology, neuronal metabolism, tissue homeostasis, and the control of gene expression in the central nervous system in healthy and diseased states. (mdpi.com)
Their results showed therapeutic promise, with observed reductions in cell death and tissue degeneration when silencing calpain-1. (asbmb.org)
Approach: Three key research areas (cancer research, autoimmune disease, and tissue and cell engineering) are considered to support the need for label-free microscopy to characterize heterogeneity and dynamics within biological systems. (bvsalud.org)

These results lend further support for a functional role of rhythmic neuronal synchronization in attentional stimulus selection. (jneurosci.org)
First is to argue that cell assemblies and CPGs form parts of a single conceptual spectrum, which we denote as 'functional networks' - recognizing that CPG outputs repeat stereotypically over time, while cell assembly behavior may be less repetitive, more flexible, and prone to modification. (degruyter.com)
Spinal cord injury (SCI) is characterized by cell death and loss of connectivity with permanent functional deficits. (jneurosci.org)
This article discusses how a combination of live-cell analysis methods deliver the required flexibility to allow these highly dynamic astrocytic models to be characterized, via quantification of their growth, motility, morphology, and functional analysis. (news-medical.net)
As an example, if a synaptic protein is synthesized in the cell body, it may need to be transported the entire length of the axon (which could be over 1 meter in a human) to reach its functional target. (nature.com)
And without this functional machinery, the study shows that long-term potentiation, a neuronal process involved in the mechanisms of memorization, is impaired and that the mice's memory is impacted. (myscience.ch)
The platform integrates single-cell sequencing, bioinformatics, functional and anatomical circuit mapping and organoids. (worldpharmanews.com)

Scientists have developed a small-molecule-inhibiting drug that in early laboratory cell tests stopped breast cancer cells from spreading and also promoted the growth of early nerve cells called neurites. (cincinnatichildrens.org)
After conducting a series of laboratory cell tests to verify the targeting and binding capabilities of Rhosin to RhoA, the researchers then tested the candidate drug's impact on cultured breast cancer cells and nerve cells. (cincinnatichildrens.org)
Rhosin worked with nerve growth factor in a dose-dependent way to promote the proliferation of branching neurites from the neuronal cells. (cincinnatichildrens.org)
The new approach can map, for example, the myelin sheaths of nerve cells, and can provide valuable information for research on multiple sclerosis and Alzheimer's disease. (mytum.de)
This gap is bridged by 'neurotransmitters', which carry nerve signals from one cell to the next. (technologynetworks.com)
This triggers an electrical impulse in the receptor-bearing cell and thus the nerve signal has moved on one neuron further. (technologynetworks.com)
This means they influence how receptive the nerve cell is to incoming signals,' says von Engelhardt. (technologynetworks.com)

The myelin layers are important to the central nervous system as they ensure the rapid and uninterrupted communication of signals along the neuronal axons. (mytum.de)
We can see the myelin sheaths of the neuronal axons and we can distinguish the layers which have a thickness of 17.6 nanometers", details Prof. Robert Feidenhans'l from the Niels-Bohr-Institute in Copenhagen. (mytum.de)

In a new study, published this week in the journal Science , researchers present a new model to describe how glutamate receptor-like proteins, or GLR proteins, function in plant cells. (upi.com)
Calcium ions are also essential to neuronal function in animals. (upi.com)
What's more, glutamate is much more important to neuronal function in animals than it is to communication among plant cells. (upi.com)
Historically, astrocytes have been considered supporters of neuronal function, but increasing evidence suggests that they directly contribute to and support neuronal activity. (news-medical.net)
Investigating the mechanisms of neuronal transport is critical in understanding neuronal function. (nature.com)
Biochemical and molecular aspects of cellular function, interactions and communication including cell cycle, apoptosis, cancer, neuronal transmission and the signal transduction pathways that integrate them. (sfu.ca)
Topics covered include cell structure and function, DNA replication and the flow of genetic information, enzyme function, metabolism and physiology of microorganisms, plants, and animals. (sfu.ca)
Phosphoinositide 3-kinase (PI3K) signaling contributes to a variety of processes, mediating many aspects of cellular function, including nutrient uptake, anabolic reactions, cell growth, proliferation, and survival. (mdpi.com)
The aim of the present work is to review cumulative evidence regarding the participation of PI3K pathways in neuronal function, focusing on their role in neuronal metabolism and transcriptional regulation of genes involved in neuronal maintenance and plasticity or on the expression of pathological hallmarks associated with neurodegeneration. (mdpi.com)
Based on its subcellular distribution, Cam kinase-Gr provides particular neuronal populations with a coordinated CA(2+)-signalling pathway which may regulate several aspects of neuronal function. (epa.gov)

The ancestor may have bequeathed both lineages with similar biochemical communication tools. (upi.com)

Cell lines are fundamental to gain detailed information about disease-related pathways on a cellular level. (edu.au)

Published 15 August 2022 Läs här om ett samarbete mellan lundaforskarna Johan Jakobsson och Malin Parmar som har lett till en ny metod för att studera åldersrelaterade hjärnsjukdomar. (lu.se)

Sozzi E, Nilsson F, Kajtez J, Parmar M, Fiorenzano A. Generation of Human Ventral Midbrain Organoids Derived from Pluripotent Stem Cells . (lu.se)

The object of our study aimed to review and to correlate genes involved in ASD and those related to ultrasonic communication in animal model studies of language-based social behavior at the PubMed database. (bvsalud.org)

The granule cell enriched Ca(2+)/calmodulin dependent protein kinase (Cam kinase-Gr) may serve as a calcium activated switch involved in neuronal communication. (epa.gov)
Enzyme immunoreactivity is prominent in the nuclei of granule cells where it is preferentially associated with regions of dispersed chromatin. (epa.gov)

Cell Stem Cell 2018 Apr 18. (chuv.ch)
Nicola Guzzi (Bellodi group) " Pseudouridylation of tRNA - Derived Fragments Steers Translational Control in Stem Cells " (Cell 2018). (lu.se)

It is so well regulated that it allows cells to encode information," José Feijó, a professor of cell biology and molecular genetics at the University of Maryland, said in a news release. (upi.com)
Communications biology , 5 (1), 173. (wisc.edu)
The use of real-time, live-cell analysis provides new possibilities and cell biology workflows. (news-medical.net)
Molecular Biology of the Cell , 7th edition. (sfu.ca)

Some cells in some multicellular organisms lack mitochondria (for example, mature mammalian red blood cells ). (wikipedia.org)

Mitochondria are an essential part of cell metabolism - any disruption in their interworking can lead to a host of cell issues. (asbmb.org)

Their observations suggest "cornichon" proteins help ferry GLRs from place to place and regulate the protein's activity in each cell. (upi.com)
With the help of cornichon proteins, GLRs work to control the concentration and flow of calcium ions in plant cells. (upi.com)
Other mutations change single protein building blocks (amino acids) in the L1 protein, impairing the protein's ability to interact with other proteins at the cell surface or preventing the protein from reaching the cell surface where it is needed. (medlineplus.gov)
The cells were co-transduced with 5 fluorescent proteins and with Lent. (cellimagelibrary.org)
Effective intracellular transport of proteins and organelles is critical in cells and is especially important for ensuring proper neuron functionality. (nature.com)
Proteins are essential for every process within a cell as well as cell-cell communication, including neurotransmission. (edu.au)
Human cell lines and primary cell culture (e.g. hippocampal cells from mutant mice) are a primary focus in our laboratory to study the role and interactions of disease-related proteins. (edu.au)

Stem Cells , 2016 Apr 34(4) 997-1010. (chuv.ch)

Most of these genes can be markers of communication deficits. (bvsalud.org)

In breast cancer for example, increased RhoA activity makes the cancer cells more invasive and causes them to spread, while a deficiency of RhoA suppresses cancer growth and progression. (cincinnatichildrens.org)
Neuroscientists study chemosensory processing by establishing chemical cues and the corresponding behavioral responses to record large-scale neuronal activity. (phys.org)

Autism spectrum disorder (ASD) manifests in early childhood and is characterized by qualitative abnormalities in social interactions, markedly aberrant communication skills, and restricted repetitive behaviors, interests, and activities (RRBs). (medscape.com)

Attention inside the receptive field of the recorded neuronal population enhanced gamma-band synchronization and strongly reduced α-band (9-11 Hz) synchronization in the prestimulus period. (jneurosci.org)

Stem cell reports , 17 (6), 1366-1379. (wisc.edu)
Stem Cell Res Ther. (lu.se)

To support them in this task, glial cells perform a series of structural, energetic and immune functions, as well as stabilizing physiological constants. (myscience.ch)

[20] This finding has led to general acceptance of the endosymbiotic hypothesis - that free-living prokaryotic ancestors of modern mitochondria permanently fused with eukaryotic cells in the distant past, evolving such that modern animals, plants, fungi, and other eukaryotes are able to respire to generate cellular energy . (wikipedia.org)

With this approach, we have identified alterations in the endolysosomal system of FTD astrocytes, a higher capacity of astrocytes to uptake and respond to glutamate, and a neuronal network hyperactivity as well as excessive synchronization. (lu.se)

Induced pluripotent stem (iPS) cell-based models hold great potential for the study of human neurological disease and disorders. (stemcell.com)

However, very few studies directly link animal oral communication and gene expression in cortical areas of language. (bvsalud.org)

Each plant cell has its own immune system, for example. (upi.com)
These include released circulating peptides and metabolites, immune factors and direct neuronal innervation. (worldpharmanews.com)

CellexalVR: A virtual reality platform to visualize and analyze single-cell omics data", iScience, 2021. (lu.se)

Communications on Pure and Applied Mathematics (2020) 73 (1): 3. (mit.edu)

Electrical coupling is also known to be important in the development of hippocampal and neocortical principal cell networks. (degruyter.com)

In tests on a human breast cancer cells, Rhosin inhibited cell growth and the formation of mammary spheres in a dose dependent manner, acting specifically on RhoA molecular targets without disrupting other critical cellular processes. (cincinnatichildrens.org)
Researchers have used 3D cell culture models in the past decade to translate molecular targets during drug discovery processes to thereby transition from an existing predominantly 2D culture environment. (phys.org)
One therapeutic approach involves targeting the molecular pathway that controls cell death. (asbmb.org)

Calcium concentration is one of the most important parameters inside all cells. (upi.com)
Put another way, calcium is the lingua franca of cell communication. (upi.com)

Scientists watched the protein's behavior inside the pollen cells of thale cress, Arabidopsis thaliana , a weed often used as a research model. (upi.com)
The number, diversity, and complexity of astroglia cells have increased significantly with evolution, and research from several groups implies that gender differences exist. (news-medical.net)
Using this data, it is possible to see the potential that live-cell analysis provides to the research of such dynamic and heterogeneous cell types. (news-medical.net)
Make that nest inaccessible by covering it with glass, for example, and the cells and mouse become disinterested, they showed in research published March 2007 in Proceedings of the National Academy of Sciences. (sciencedaily.com)
The research team succeeded in demonstrating this by suppressing VGLUT expression by these hybrid cells. (myscience.ch)
Lab on a Chip publishes full research papers, technical notes, urgent communications, critical and tutorial reviews, and mini-reviews. (phys.org)

Such precise synchronization could enhance the postsynaptic impact of cells carrying behaviorally relevant information. (jneurosci.org)

The L1 protein spans the cell membrane, with one end of the protein inside the cell and the other end projecting from the outer surface of the cell. (medlineplus.gov)
Mitochondria have a double membrane structure and use aerobic respiration to generate adenosine triphosphate (ATP), which is used throughout the cell as a source of chemical energy . (wikipedia.org)
One of the key elements for this cell-type specific information transfer is the adaptive changes in spike threshold, i.e. the membrane potential at which action potentials are generated. (ru.nl)

In addition to supplying cellular energy, mitochondria are involved in other tasks, such as signaling , cellular differentiation , and cell death , as well as maintaining control of the cell cycle and cell growth . (wikipedia.org)

Cortex, Hippocampus, and Cerebellum astroglia were seeded in 96-well plates at 2,000 cells/well. (news-medical.net)

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