• cortical neurons
  • In this study, oxygen-glucose deprivation/reoxygenation (OGD/R) in primary cortical neurons and unilateral ligation of the common carotid artery (CCL) in 7-day-old postnatal Sprague Dawley (SD) rats followed by exposure to a hypoxic environment were used to mimic an HIBD episode. (springer.com)
  • motor neuron
  • An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria. (springer.com)
  • onset
  • Amyotrophic lateral sclerosis (ALS) is a fatal, adult-onset neurodegenerative disease in which motor neurons (MNs) are selectively lost. (jneurosci.org)
  • diseases
  • Catalpol is being studied for its neuroprotective effects, with potential applications in Alzheimer and Parkinson diseases, as well as in ischemia and other conditions associated with aging. (drugs.com)