Nervous System DiseasesSelenoprotein PBlood-Nerve BarrierNeurologic ExaminationBrainSelenomethionineBrain InjuriesBrain DiseasesDisease Models, AnimalNerve DegenerationNeurodegenerative DiseasesNeuroprotective AgentsNeuronsBehavior, AnimalMice, KnockoutMice, Inbred C57BLAnalysis of VarianceMagnetic Resonance ImagingSpinal CordTime FactorsTreatment OutcomeRats, Sprague-DawleyErectile DysfunctionVentricular Dysfunction, LeftMutationCells, CulturedVentricular DysfunctionSexual Dysfunction, PhysiologicalSexual Dysfunctions, PsychologicalEndothelium, VascularVentricular Dysfunction, RightOxidative StressPrimary Graft DysfunctionPenile ErectionVasodilationDiastoleAutonomic Nervous System DiseasesMitochondriaMyocardiumHeart FailureMyocardial ContractionEchocardiographyMultiple Organ FailureCardiomyopathiesVasodilator AgentsImpotence, VasculogenicMitochondrial DiseasesNitric OxideCognition DisordersSystoleBiological MarkersVentricular Function, LeftPenisStroke VolumeReactive Oxygen SpeciesHeartHeart Failure, DiastolicNitric Oxide Synthase Type IIIKidney DiseasesHemodynamicsSeverity of Illness IndexRisk FactorsBlood PressureProspective StudiesVascular DiseasesVentricular RemodelingAcetylcholineEchocardiography, DopplerCase-Control StudiesAgingMice, TransgenicRats, WistarMyocytes, CardiacSulfonesSphincter of Oddi DysfunctionNeuropsychological TestsHeart DiseasesEndothelial CellsMicrocirculationFollow-Up StudiesHypertensionChronic DiseaseKidneyDose-Response Relationship, DrugSignal TransductionBrachial ArteryNatriuretic Peptide, BrainDiabetes Mellitus, ExperimentalSepsisSuperoxidesPhosphodiesterase 5 InhibitorsNitroprussideApoptosisCoronary CirculationInflammationRetrospective StudiesHeart VentriclesHeart RateRenal InsufficiencyPredictive Value of Tests