• The most common soft-tissue primary malignant tumors are fibrosarcomas (desmoids, neurofibrosarcomas) and malignant fibrous histiocytomas. (msdmanuals.com)
  • The p53 (a tumor suppressor gene in the normal population) genome on 17p in neurofibrosarcoma patients is mutated, increasing the probability of cancer. (wikipedia.org)
  • The most conclusive test for a patient with a potential neurofibrosarcoma is a tumor biopsy (taking a sample of cells directly from the tumor itself). (wikipedia.org)
  • For patients who have neurofibrosarcomas in an extremity, if the tumor is vascularized (has its own blood supply) and has many nerves going through it and/or around it, amputation of the extremity may be necessary. (wikipedia.org)
  • Histologically, the mass was identified as a peripheral nerve sheath tumor (neurofibrosarcoma). (avma.org)
  • Peripheral Nerve Sheath Tumor Two years ago, Sheena was diagnosed with neurofibrosarcoma, or peripheral nerve. (askavetquestion.com)
  • In 50/50 Anna Kenrick plays Katherine McKay, a young, inexperienced therapist who is assigned to help Joseph Gordon-Levitt deal the fact he has schwannoma neurofibrosarcoma and presumably the fact that no matter how many great Christopher Nolan or Rian Johnson films he appears in, we'll all always think of him as the kid in Third Rock From The Sun. (prairiesmokepress.com)
  • There is no well-known cause of neurofibrosarcoma, however, certain genetic mutations are held responsible for the development of these tumours. (withoutaribbon.org)
  • Soft tissue sarcomas have been linked within families, so it is hypothesized that neurofibrosarcoma may be genetic, although researchers still do not know the exact cause of the disease. (wikipedia.org)
  • A neurofibrosarcoma is a type of connective tissue (tissues that bind, separate, or support other tissues or organs) cancer that surrounds the nerves, these tissue cells receive the signals from the brain and stimulate the movements. (withoutaribbon.org)
  • Neurofibrosarcoma is rare cancer, meaning it is not as well known as other forms of cancer. (withoutaribbon.org)
  • If you suffer from rare cancer such as Neurofibrosarcoma, we can help and support you through your journey thanks to the generous donations we receive. (withoutaribbon.org)
  • Treatment for neurofibrosarcoma is similar to that of other cancers. (wikipedia.org)
  • In some instances, the oncologist may choose chemotherapy drugs when treating a patient with neurofibrosarcoma, usually in conjunction with surgery. (wikipedia.org)
  • The neurofibrosarcoma showed low AgNOR count as compared to other soft tissues sarcomas. (aleijten.com)
  • since p53 is inactivated in neurofibrosarcoma patients, they are much more susceptible to developing tumors. (wikipedia.org)
  • Although I will focus on how the genetic abnormalities and the formation of NF1 neurofibromas are interrelated- with a less intense discussion of neurofibrosarcomas- I also wish to emphasize that the NF1 phenotype entails much more than tumors of the central and peripheral nervous systems and, conversely, that NF1 neurofibromas cannot be explained solely in terms of NF1 mutations and abnormal function of neurofibromin. (medscape.com)
  • These findings suggest that methylation of some tumour-related genes may play a significant role in the tumourigenesis of neurofibromas/neurofibrosarcomas. (nih.gov)
  • For patients who have neurofibrosarcomas in an extremity, if the tumor is vascularized (has its own blood supply) and has many nerves going through it and/or around it, amputation of the extremity may be necessary. (wikipedia.org)
  • The p53 (a tumor suppressor gene in the normal population) genome on 17p in neurofibrosarcoma patients is mutated, increasing the probability of cancer. (wikipedia.org)
  • Peripheral and central nervous system neoplasms occur frequently, especially OPTIC NERVE GLIOMA and NEUROFIBROSARCOMA. (edu.au)
  • Soft tissue sarcomas have been linked within families, so it is hypothesized that neurofibrosarcoma may be genetic, although researchers still do not know the exact cause of the disease. (wikipedia.org)
  • Treatment for neurofibrosarcoma is similar to that of other cancers. (wikipedia.org)